Ionis Pharmaceuticals, Inc. (IONS)

NASDAQ: IONS · IEX Real-Time Price · USD
37.31
-0.31 (-0.82%)
May 17, 2024, 4:00 PM EDT - Market closed
-0.82%
Market Cap 5.42B
Revenue (ttm) 776.62M
Net Income (ttm) -384.77M
Shares Out 145.97M
EPS (ttm) -2.67
PE Ratio n/a
Forward PE 90.91
Dividend n/a
Ex-Dividend Date n/a
Volume 994,682
Open 37.55
Previous Close 37.62
Day's Range 36.56 - 37.66
52-Week Range 36.37 - 54.44
Beta 0.41
Analysts Buy
Price Target 59.36 (+59.1%)
Earnings Date May 7, 2024

About IONS

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an antisense injection for the treatment of polyneuropathy caused by hereditary transthyretin amyloidosis in adults; and WAYLIVRA, an antisense medicine for treatment for familial chylomicronemia syndrome (FCS) and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen ... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date May 17, 1991
Employees 927
Stock Exchange NASDAQ
Ticker Symbol IONS
Full Company Profile

Financial Performance

In 2023, IONS's revenue was $787.65 million, an increase of 34.10% compared to the previous year's $587.37 million. Losses were -$366.29 million, 35.8% more than in 2022.

Financial Statements

Analyst Forecast

According to 12 analysts, the average rating for IONS stock is "Buy." The 12-month stock price forecast is $59.36, which is an increase of 59.10% from the latest price.

Price Target
$59.36
(59.10% upside)
Analyst Consensus: Buy
Stock Forecasts

News

Biogen and Ionis Pharma shares slide as they end development of ALS treatment

The stocks of Biogen Inc. and Ionis Pharmaceuticals Inc. were lower Thursday, after the partners said they were terminating development of a treatment for the fatal disease Amyotrophic Lateral Scleros...

Other symbols: BIIB
2 days ago - Market Watch

Biogen, Ionis to discontinue development of ALS drug

Biogen and Ionis Pharmaceuticals said on Thursday they will terminate the development of their experimental treatment for amyotrophic lateral sclerosis (ALS) after failing to show improvement in patie...

Other symbols: BIIB
2 days ago - Reuters

Ionis and Biogen Announce Topline Phase 1/2 Study Results of Investigational Drug in Amyotrophic Lateral Sclerosis

Development of BIIB105, an investigational antisense oligonucleotide for amyotrophic lateral sclerosis (ALS), will be discontinued based on data from the Phase 1/2 ALSpire study Biogen and Ionis conti...

Other symbols: BIIB
2 days ago - PRNewsWire

Ionis announces positive topline results from Phase 1/2a trial of ION582 for Angelman syndrome

ION582 demonstrated consistent improvements across multiple functional domains in Angelman syndrome patients ION582 was safe and well tolerated at all dose levels Ionis plans to move ION582 into pivot...

2 days ago - PRNewsWire

Ionis to host 2024 virtual Annual Meeting of Stockholders

CARLSBAD, Calif. , May 15, 2024 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will conduct its 2024 virtual Annual Meeting of Stockholders followed by a ge...

3 days ago - PRNewsWire

Ionis reports first quarter 2024 financial results

WAINUA TM  launch on track; EU and Canada approval decisions expected this year Olezarsen NDA submitted to FDA for FCS; preparing EU regulatory submission Positive Phase 3 donidalorsen data for HAE; p...

11 days ago - PRNewsWire

Ionis Publishes 2023 Corporate Responsibility Report

Established new corporate responsibility strategic pillars and actionable goals Received approval for two Ionis-discovered medicines in 2023, and continued to advance a broad pipeline poised to bring ...

23 days ago - PRNewsWire

Ionis to hold first quarter 2024 financial results webcast

Webcast scheduled for Tuesday, May 7 at 11:30 a.m. Eastern Time CARLSBAD, Calif.

25 days ago - PRNewsWire

Ionis presents positive results from Phase 3 Balance study of olezarsen for familial chylomicronemia syndrome

–         Olezarsen met the primary endpoint with statistically significant reduction of fasting triglycerides and showed substantial, clinically meaningful reduction in acute pancreatitis events – – ...

5 weeks ago - PRNewsWire

Ionis to present at upcoming investor conferences

CARLSBAD, Calif. , April 1, 2024 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will participate in fireside chats at the following investor conferences: 23...

6 weeks ago - PRNewsWire

Ionis to hold olezarsen Phase 3 data webcast

Webcast scheduled for Monday, April 8 at 10:00 a.m. Eastern Time CARLSBAD, Calif.

7 weeks ago - PRNewsWire

Positive olezarsen Phase 3 data in familial chylomicronemia syndrome to be presented at 2024 American College of Cardiology (ACC) annual meeting

–  First presentation of pivotal results showing significant reduction in triglycerides and substantial reduction in acute pancreatitis events in patients with rare, life-threatening disease, for whic...

7 weeks ago - PRNewsWire

Ionis Pharma's fatty liver disease drug succeeds in mid-stage trial

Ionis Pharmaceuticals said on Wednesday its experimental drug to treat a type of fatty liver disease met the main goal of a mid-stage trial.

2 months ago - Reuters

Ionis announces positive results from Phase 2 study of ION224, an investigational medicine demonstrating clinical efficacy in the treatment of NASH/MASH

Significant improvement in steatohepatitis with > 2 point improvement in NAS score without worsening fibrosis, the primary endpoint of the study Achieved key secondary endpoint of MASH resolution with...

2 months ago - PRNewsWire

Ionis announces new chief global product strategy officer to lead next phase of commercial growth

Kyle Jenne  rejoins company to lead commercial strategy Onaiza Cadoret-Manier departing for new career opportunity With broad commercial capabilities in place, Ionis ready to execute on its first inde...

2 months ago - PRNewsWire

Ionis reports fourth quarter and full year 2023 financial results

WAINUA™  approved with launch underway; on track for EU and Canada approval decisions this year Positive Phase 3 olezarsen and donidalorsen data, preparing regulatory submissions for FCS and HAE, resp...

3 months ago - PRNewsWire

Olezarsen receives Orphan Drug designation from U.S. FDA for familial chylomicronemia syndrome

CARLSBAD, Calif. , Feb. 15, 2024 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) announced today that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug designation to the ...

3 months ago - PRNewsWire

Eplontersen granted U.S. FDA Fast Track designation for patients with transthyretin-mediated amyloid cardiomyopathy

CARLSBAD, Calif. , Feb. 8, 2024 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) announced today that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to Ionis ...

3 months ago - PRNewsWire

Ionis to hold fourth quarter and full year 2023 financial results webcast

Webcast scheduled for Wednesday, February 21 at 11:30 a.m. Eastern Time CARLSBAD, Calif.

3 months ago - PRNewsWire

Vect-Horus Enters Exclusive License Agreement with Ionis Pharmaceuticals to Advance Systemic Delivery of RNA-Targeted Medicines for Neurological Diseases

MARSEILLE, France--(BUSINESS WIRE)--Vect-Horus announced it has entered into a global license agreement with Ionis Pharmaceuticals, Inc. (Nasdaq: IONS).

3 months ago - Business Wire

Ionis Pharma's genetic disease drug succeeds in late-stage study

Ionis Pharmaceuticals said on Monday its therapy for the treatment of a rare genetic disease met the main goal in a late-stage trial.

4 months ago - Reuters

Ionis announces positive topline results from Phase 3 OASIS-HAE study of investigational donidalorsen in patients with hereditary angioedema

Donidalorsen met the primary endpoint with a statistically significant reduction in the rate of HAE attacks in patients treated every 4 weeks or patients treated every 8 weeks  Donidalorsen demonstrat...

4 months ago - PRNewsWire

Ionis poised for continued momentum in 2024 with product launches and key advances in robust pipeline of investigational medicines for serious diseases

– Numerous value-driving commercial, regulatory and pipeline milestones anticipated – CARLSBAD, Calif. , Jan. 8, 2024 /PRNewswire/ -- Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced highlig...

4 months ago - PRNewsWire

Ionis Pharmaceuticals, AstraZeneca get FDA approval for rare genetic disease treatment

Ionis Pharmaceuticals IONS, +1.61% and AstraZeneca's AZN, +0.79% Wainua has been approved by the U.S. Food and Drug Administration for treating a symptom of a rare genetic disease.

Other symbols: AZN
5 months ago - Market Watch

WAINUA™ (eplontersen) granted regulatory approval in the U.S. for the treatment of adults with polyneuropathy of hereditary transthyretin-mediated amyloidosis

U.S. FDA approval based on Phase 3 NEURO-TTRansform results showing WAINUA demonstrated consistent and sustained benefit halting neuropathy disease progression and improving neuropathy impairment and ...

5 months ago - PRNewsWire