Alnylam Pharmaceuticals Ratios and Metrics

Market cap in millions BRL. Fiscal year is January - December.

Millions BRL. Fiscal year is Jan - Dec.

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Mar '26 Mar 16, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Market Cap	218,807	279,694	161,656	127,937	156,484	108,290
Market Cap Growth	18.23%	73.02%	26.36%	-18.24%	44.51%	34.68%
Enterprise Value	219,126	270,791	154,003	121,691	151,627	100,434
PE Ratio	126.62	170.67	-107.94	-54.38	-25.55	-23.55
Forward PE	31.42	60.03	-	-	-	-
PS Ratio	10.70	14.17	13.53	13.17	28.39	24.14
PB Ratio	50.34	66.70	453.50	-109.13	-186.13	34.65
P/TBV Ratio	14.24	67.86	447.73	-108.36	-182.78	34.15
P/FCF Ratio	85.36	113.11	-714.37	574.04	-48.02	-28.38
P/OCF Ratio	75.80	100.44	-3660.27	231.17	-54.41	-31.76
EV/Sales Ratio	11.16	13.72	12.89	12.53	27.51	22.39
EV/EBITDA Ratio	65.64	91.46	-241.10	-100.40	-38.53	-28.59
EV/EBIT Ratio	82.66	101.61	-163.86	-81.16	-36.35	-26.67
EV/FCF Ratio	85.48	109.51	-680.55	546.02	-46.53	-26.32
Debt / Equity Ratio	1.56	1.56	18.69	-5.73	-8.08	1.63
Debt / EBITDA Ratio	2.29	2.29	-10.78	-5.72	-1.78	-1.51
Debt / FCF Ratio	2.75	2.75	-30.43	31.12	-2.15	-1.39
Net Debt / Equity Ratio	-2.07	-2.07	-20.84	5.14	5.51	-2.44
Net Debt / EBITDA Ratio	-2.92	-2.92	11.63	4.97	1.18	2.17
Net Debt / FCF Ratio	-3.50	-3.50	32.84	-27.03	1.42	2.00
Asset Turnover	0.81	0.81	0.56	0.50	0.29	0.24
Inventory Turnover	8.46	8.46	3.86	2.85	1.57	1.73
Quick Ratio	2.51	2.51	2.61	2.86	3.16	3.79
Current Ratio	2.76	2.76	2.78	3.08	3.51	4.04
Return on Equity (ROE)	131.93%	73.28%	362.29%	232.40%	-526.14%	-106.31%
Return on Assets (ROA)	10.58%	10.58%	-3.23%	-7.77%	-21.92%	-20.12%
Return on Invested Capital (ROIC)	63.85%	63.85%	-20.29%	-43.01%	-108.72%	-76.10%
Return on Capital Employed (ROCE)	15.31%	15.31%	-5.98%	-10.01%	-27.42%	-24.57%
Earnings Yield	0.79%	0.59%	-0.93%	-1.84%	-3.91%	-4.25%
FCF Yield	1.17%	0.88%	-0.14%	0.17%	-2.08%	-3.52%
Buyback Yield / Dilution	-0.47%	-0.47%	-1.00%	-0.61%	-0.88%	-1.21%

Updated Dec 31, 2025. Data Source: Fiscal.ai. Standard template. Financial Sources.