Alnylam Pharmaceuticals, Inc. (LON: 0HD2)
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238.33
-6.27 (-2.56%)
Dec 23, 2024, 6:17 PM BST

Alnylam Pharmaceuticals Company Description

Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing, and commercializing novel therapeutics based on ribonucleic acid interference.

Its marketed products include ONPATTRO (patisiran) for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults; AMVUTTRA for the treatment of hATTR amyloidosis with polyneuropathy in adults; GIVLAARI for the treatment of adults with acute hepatic porphyria; and OXLUMO for the treatment of primary hyperoxaluria type 1.

In addition, the company develops patisiran for the treatment of transthyretin amyloidosis, or ATTR amyloidosis, with cardiomyopathy; cemdisiran to treat complement-mediated diseases; Belcesiran for the treatment of alpha-1 liver disease; Elebsiran to treat chronic HBV infection; Zilebesiran to treat hypertension; ALN-APP to treat Alzheimer’s disease and cerebral amyloid angiopathy; and ALN-HSD to treat NASH.

Further, it offers Fitusiran for the treatment of hemophilia, Inclisiran to treat hypercholesterolemia, lumasiran for the treatment of advanced PH1, and vutrisiran for the treatment of ATTR amyloidosis, which is in phase 3 clinical trial.

Alnylam Pharmaceuticals, Inc. has strategic collaborations with Regeneron Pharmaceuticals, Inc. to discover, develop, and commercialize RNAi therapeutics for a range of diseases by addressing therapeutic targets expressed in the eye and CNS; and Roche to develop pharmaceutical products containing zilebesiran.

It also has license and collaboration agreements with Novartis AG; Vir Biotechnology, Inc.; Dicerna Pharmaceuticals, Inc.; Ionis Pharmaceuticals, Inc.; and PeptiDream, Inc. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts.

Alnylam Pharmaceuticals, Inc.
Country United States
Founded 2002
Industry Medical - Pharmaceuticals
Sector Healthcare
Employees 2,100
CEO Yvonne Greenstreet

Contact Details

Address:
675 West Kendall Street
Cambridge, Delaware 02142
United States
Phone 617 551 8200
Website alnylam.com

Stock Details

Ticker Symbol 0HD2
Exchange London Stock Exchange
Fiscal Year January - December
Reporting Currency USD
ISIN Number US02043Q1076
SIC Code 2836

Key Executives

Name Position
Yvonne Greenstreet Chief Executive Officer
Jeffrey Poulton Chief Financial Officer