Alnylam Pharmaceuticals, Inc. (LON:0HD2)
London flag London · Delayed Price · Currency is GBP · Price in USD
340.30
+2.36 (0.70%)
At close: Feb 20, 2026

Alnylam Pharmaceuticals Company Description

Alnylam Pharmaceuticals, Inc. discovers, develops, manufactures, and commercializes therapeutics based on ribonucleic acid interference in the United States, Europe, and internationally.

The company offers ONPATTRO for hereditary transthyretin-mediated (hATTR) amyloidosis; AMVUTTRA for ATTR and hATTR amyloidosis; Leqvio for hypercholesterolemia; Qfitlia for hemophilia A or B; GIVLAARI for acute hepatic porphyria; and OXLUMO for primary hyperoxaluria type 1.

It also develops a range of products in Phase 3 trial, such as Nucresiran for ATTR amyloidosis; Zilebesiran for hypertension; Cemdisiran for myasthenia gravis, paroxysmal nocturnal hemoglobinuria, and geographic atrophy; and Elebsiran for hepatitis D virus infections.

In addition, the company is developing various products in Phase 2 trial, including Rapirosiran for metabolic dysfunction-associated steatohepatitis; ALN-ANG3 for diabetic kidney disease; ALN-4324 for type 2 diabetes mellitus; Mivelsiran for cerebral amyloid angiopathy, as well as in Phase 1 trial for Alzheimer’s disease; and ALN-6400 for bleeding disorders.

Further, it develops a range of products in Phase 1 trial, such as ALN-2232 for obesity and weight management; ALN-PNP for non-alcoholic fatty liver disease; ALN-APOC3 for dyslipidemia; ALN-CIDEB for metabolic dysfunction-associated steatohepatitis; ALN-HTT02 for Huntington’s disease; ALN-5288 for Alzheimer’s disease; ALN-SOD for SOD1 amyotrophic lateral sclerosis; ALN-SNCA for Parkinson’s disease; AG-236 for polycythemia vera; ALN-CFB for paroxysmal nocturnal hemoglobinuria; ALN-BCAT for hepatocellular carcinoma; and ALN-4285, ALN-4915, and ALN-F1202 for healthy volunteers.

The company has collaborations with Regeneron Pharmaceuticals, Inc.; Roche Holding AG; Sanofi S.A.; Novartis AG; PeptiDream, Inc; Dicerna Pharmaceuticals, Inc.; and Ionis Pharmaceuticals, Inc. Alnylam Pharmaceuticals, Inc. was founded in 2002 and is headquartered in Cambridge, Massachusetts.

Alnylam Pharmaceuticals, Inc.
CountryUnited States
Founded2002
IndustryMedical - Pharmaceuticals
SectorHealthcare
Employees2,500
CEOYvonne Greenstreet

Contact Details

Address:
675 West Kendall Street
Cambridge, Massachusetts 02142
United States
Phone617 551 8200
Websitealnylam.com

Stock Details

Ticker Symbol0HD2
ExchangeLondon Stock Exchange
Stock TypeCommon Stock
Fiscal YearJanuary - December
Reporting CurrencyUSD
ISIN NumberUS02043Q1076
SIC Code2836

Key Executives

NamePosition
Dr. Yvonne L. Greenstreet M.B.A., M.D.Chief Executive Officer and Director
Dr. Phillip A. Sharp Ph.D.Co-Founder, Member of the Scientific Advisory Board
Jeffrey V. Poulton M.B.A.Chief Financial Officer and Executive Vice President
Dr. Kevin Joseph Fitzgerald Ph.D.Executive Vice President, Chief Scientific Officer and Head of Early Research and Early Development
Dr. Pushkal P. Garg M.D.Chief Research and Development Officer
Tolga Tanguler M.B.A.Executive Vice President and Chief Commercial Officer
Timothy J. MainesChief Technical Operations and Quality Officer
Piyush Sharma J.D.Chief Ethics and Compliance Officer
Bryan Andrew Supran J.D.Chief Legal Officer
Christine Regan AkincChief Corporate Communications Officer