Ionis Pharmaceuticals, Inc. (LON:0JDI)

Ionis Pharmaceuticals Statistics

Total Valuation

LON:0JDI has a market cap or net worth of GBP 7.16 billion. The enterprise value is 6.93 billion.

Market Cap	7.16B
Enterprise Value	6.93B

Important Dates

The next estimated earnings date is Wednesday, November 5, 2025.

Earnings Date	Nov 5, 2025
Ex-Dividend Date	n/a

Share Statistics

Current Share Class	159.39M
Shares Outstanding	n/a
Shares Change (YoY)	+7.95%
Shares Change (QoQ)	+14.87%
Owned by Insiders (%)	n/a
Owned by Institutions (%)	n/a
Float	158.05M

Valuation Ratios

PE Ratio	n/a
Forward PE	n/a
PS Ratio	10.39
PB Ratio	15.53
P/TBV Ratio	15.53
P/FCF Ratio	n/a
P/OCF Ratio	n/a
PEG Ratio	n/a

Enterprise Valuation

EV / Earnings	-35.42
EV / Sales	9.99
EV / EBITDA	n/a
EV / EBIT	n/a
EV / FCF	-32.76

Financial Position

The company has a current ratio of 2.87, with a Debt / Equity ratio of 3.14.

Current Ratio	2.87
Quick Ratio	2.61
Debt / Equity	3.14
Debt / EBITDA	n/a
Debt / FCF	-6.84
Interest Coverage	-2.92

Financial Efficiency

Return on equity (ROE) is -59.91% and return on invested capital (ROIC) is -6.85%.

Return on Equity (ROE)	-59.91%
Return on Assets (ROA)	-5.87%
Return on Invested Capital (ROIC)	-6.85%
Return on Capital Employed (ROCE)	-12.77%
Revenue Per Employee	644,586
Profits Per Employee	-183,135
Employee Count	1,069
Asset Turnover	0.33
Inventory Turnover	48.06

Taxes

Income Tax	-4.54M
Effective Tax Rate	n/a

Stock Price Statistics

The stock price has increased by +49.67% in the last 52 weeks.

Beta (5Y)	n/a
52-Week Price Change	+49.67%
50-Day Moving Average	46.13
200-Day Moving Average	36.76
Relative Strength Index (RSI)	69.93
Average Volume (20 Days)	2,870

Short Selling Information

Short Interest	n/a
Short Previous Month	n/a
Short % of Shares Out	n/a
Short % of Float	n/a
Short Ratio (days to cover)	4.28

Income Statement

In the last 12 months, LON:0JDI had revenue of GBP 689.06 million and -195.77 million in losses. Loss per share was -1.26.

Revenue	689.06M
Gross Profit	36.54M
Operating Income	-194.53M
Pretax Income	-200.31M
Net Income	-195.77M
EBITDA	-186.25M
EBIT	-194.53M
Loss Per Share	-1.26

Balance Sheet

The company has 1.67 billion in cash and 1.45 billion in debt, giving a net cash position of 225.52 million.

Cash & Cash Equivalents	1.67B
Total Debt	1.45B
Net Cash	225.52M
Net Cash Per Share	n/a
Equity (Book Value)	461.10M
Book Value Per Share	2.90
Working Capital	1.23B

Cash Flow

In the last 12 months, operating cash flow was -168.29 million and capital expenditures -43.38 million, giving a free cash flow of -211.67 million.

Operating Cash Flow	-168.29M
Capital Expenditures	-43.38M
Free Cash Flow	-211.67M
FCF Per Share	n/a

Margins

Gross margin is 5.30%, with operating and profit margins of -28.23% and -28.41%.

Gross Margin	5.30%
Operating Margin	-28.23%
Pretax Margin	-29.07%
Profit Margin	-28.41%
EBITDA Margin	-27.03%
EBIT Margin	-28.23%
FCF Margin	n/a

Dividends & Yields

LON:0JDI does not appear to pay any dividends at this time.

Dividend Per Share	n/a
Dividend Yield	n/a
Dividend Growth (YoY)	n/a
Years of Dividend Growth	n/a
Payout Ratio	n/a
Buyback Yield	-7.95%
Shareholder Yield	n/a
Earnings Yield	-2.73%
FCF Yield	-2.96%

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value	n/a
Lynch Upside	n/a
Graham Number	n/a
Graham Upside	n/a

Stock Splits

This stock does not have any record of stock splits.

Last Split Date	n/a
Split Type	n/a
Split Ratio	n/a

Scores

LON:0JDI has an Altman Z-Score of 1.11 and a Piotroski F-Score of 4. A Z-score under 3 suggests an increased risk of bankruptcy.

Altman Z-Score	1.11
Piotroski F-Score	4