Ionis Pharmaceuticals, Inc. (LON:0JDI)

Ionis Pharmaceuticals Statistics

Total Valuation

LON:0JDI has a market cap or net worth of GBP 8.81 billion. The enterprise value is 8.76 billion.

Market Cap	8.81B
Enterprise Value	8.76B

Important Dates

The next estimated earnings date is Wednesday, April 29, 2026.

Earnings Date	Apr 29, 2026
Ex-Dividend Date	n/a

Share Statistics

Current Share Class	165.19M
Shares Outstanding	n/a
Shares Change (YoY)	+7.02%
Shares Change (QoQ)	+1.40%
Owned by Insiders (%)	0.77%
Owned by Institutions (%)	103.97%
Float	163.85M

Valuation Ratios

PE Ratio	n/a
Forward PE	n/a
PS Ratio	12.57
PB Ratio	24.25
P/TBV Ratio	24.25
P/FCF Ratio	n/a
P/OCF Ratio	n/a
PEG Ratio	n/a

Enterprise Valuation

EV / Earnings	-30.92
EV / Sales	12.42
EV / EBITDA	n/a
EV / EBIT	n/a
EV / FCF	-36.85

Financial Position

The company has a current ratio of 3.83, with a Debt / Equity ratio of 5.35.

Current Ratio	3.83
Quick Ratio	3.51
Debt / Equity	5.35
Debt / EBITDA	n/a
Debt / FCF	-8.17
Interest Coverage	-4.22

Financial Efficiency

Return on equity (ROE) is -70.80% and return on invested capital (ROIC) is -90.05%.

Return on Equity (ROE)	-70.80%
Return on Assets (ROA)	-7.31%
Return on Invested Capital (ROIC)	-90.05%
Return on Capital Employed (ROCE)	-13.92%
Weighted Average Cost of Capital (WACC)	5.62%
Revenue Per Employee	500,126
Profits Per Employee	-202,119
Employee Count	1,402
Asset Turnover	0.29
Inventory Turnover	82.58

Taxes

In the past 12 months, LON:0JDI has paid 1.33 million in taxes.

Income Tax	1.33M
Effective Tax Rate	n/a

Stock Price Statistics

The stock price has increased by +105.80% in the last 52 weeks. The beta is 0.36, so LON:0JDI's price volatility has been lower than the market average.

Beta (5Y)	0.36
52-Week Price Change	+105.80%
50-Day Moving Average	79.99
200-Day Moving Average	63.93
Relative Strength Index (RSI)	33.12
Average Volume (20 Days)	510

Short Selling Information

Short Interest	n/a
Short Previous Month	n/a
Short % of Shares Out	n/a
Short % of Float	n/a
Short Ratio (days to cover)	6.92

Income Statement

In the last 12 months, LON:0JDI had revenue of GBP 701.18 million and -283.37 million in losses. Loss per share was -1.77.

Revenue	701.18M
Gross Profit	9.05M
Operating Income	-283.59M
Pretax Income	-282.04M
Net Income	-283.37M
EBITDA	-274.34M
EBIT	-283.59M
Loss Per Share	-1.77

Balance Sheet

The company has 1.99 billion in cash and 1.94 billion in debt, with a net cash position of 47.99 million.

Cash & Cash Equivalents	1.99B
Total Debt	1.94B
Net Cash	47.99M
Net Cash Per Share	n/a
Equity (Book Value)	363.39M
Book Value Per Share	2.23
Working Capital	1.64B

Cash Flow

In the last 12 months, operating cash flow was -199.56 million and capital expenditures -38.22 million, giving a free cash flow of -237.78 million.

Operating Cash Flow	-199.56M
Capital Expenditures	-38.22M
Free Cash Flow	-237.78M
FCF Per Share	n/a

Margins

Gross margin is 1.29%, with operating and profit margins of -40.45% and -40.41%.

Gross Margin	1.29%
Operating Margin	-40.45%
Pretax Margin	-40.22%
Profit Margin	-40.41%
EBITDA Margin	-39.13%
EBIT Margin	-40.45%
FCF Margin	n/a

Dividends & Yields

LON:0JDI does not appear to pay any dividends at this time.

Dividend Per Share	n/a
Dividend Yield	n/a
Dividend Growth (YoY)	n/a
Years of Dividend Growth	n/a
Payout Ratio	n/a
Buyback Yield	-7.02%
Shareholder Yield	-7.02%
Earnings Yield	-3.22%
FCF Yield	-2.70%

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value	n/a
Lynch Upside	n/a
Graham Number	n/a
Graham Upside	n/a

Stock Splits

This stock does not have any record of stock splits.

Last Split Date	n/a
Split Type	n/a
Split Ratio	n/a

Scores

LON:0JDI has an Altman Z-Score of 1.13 and a Piotroski F-Score of 3. A Z-score under 3 suggests an increased risk of bankruptcy.

Altman Z-Score	1.13
Piotroski F-Score	3