London · Delayed Price · Currency is GBP · Price in USD Verastem Company Description
Verastem, Inc., a development-stage biopharmaceutical company, focuses on developing and commercializing drugs for the treatment of cancer in the United States.
Its product candidates are Avutometinib, an orally available small molecule RAF/MEK clamp that inhibits the ras sarcoma RAF/MEK, ERK mitogen activated pathway kinase pathway which is involved in cell proliferation, migration, transformation, and survival of tumor cells; and Defactinib, an oral small molecule inhibitor of FAK and proline-rich tyrosine kinase for various solid tumors.
The company is involved in clinical studies, including RAMP 301, a randomized global confirmatory trial to evaluate the combination of Avutometinib and Defactinib for the treatment of patients with recurrent low-grade serous ovarian cancer; RAMP 201, an adaptive two-part multicenter, parallel cohort, randomized open label trial to evaluate the efficacy and safety of Avutometinib and in combination with Defactinib; and FRAME, an investigation of Avutometinib and Defactinib in patients with KRAS mutant cancers and subsequent analyses; and RAMP 204 and 205.
It has license agreements with Chugai Pharmaceutical Co., Ltd. for the development, commercialization, and manufacture of products containing Avutometinib; and Pfizer Inc. to research, develop, manufacture, and commercialize products containing Pfizer’s inhibitors of FAK for therapeutic, diagnostic, and prophylactic uses in humans.
In addition, it has a clinical collaboration agreement with Amgen, Inc. to evaluate the combination of Avutometinib with Amgen’s KRAS-G12C inhibitor LUMAKRAS which in Phase 1/2 trial entitled RAMP 203; and a discovery and development collaboration with GenFleet Therapeutics to advance new programs targeting RAS pathway-driven cancers.
Verastem, Inc. was incorporated in 2010 and is headquartered in Needham, Massachusetts.
| Country | United States |
| Founded | 2010 |
| Industry | Medical - Pharmaceuticals |
| Sector | Healthcare |
| Employees | 78 |
| CEO | Daniel Paterson |
Contact Details
Address: 117 Kendrick Street Needham, Massachusetts 02494 United States | |
| Phone | 781 292 4200 |
| Website | verastem.com |
Stock Details
| Ticker Symbol | 0LOV |
| Exchange | London Stock Exchange |
| Stock Type | Common Stock |
| Fiscal Year | January - December |
| Reporting Currency | USD |
| ISIN Number | US92337C2035 |
| SIC Code | 2836 |
Key Executives
| Name | Position |
|---|---|
| Daniel W. Paterson | President, Chief Executive Officer and Director |
| Daniel Calkins | Chief Financial Officer |
| Dr. Michael Glen Kauffman M.D., Ph.D. | President of Development and Director |
| Dr. Robert A. Weinberg Ph.D. | Co-Founder and Chair of Scientific Advisory Board |
| Dr. Michelle Detwiler M.D., Ph.D. | Co-Founder |
| Dr. Jonathan Pachter Ph.D. | Chief Scientific Officer |
| Julissa Viana | Vice President of Corporate Communications and Investor Relations |
| Mark J. Wanda | Senior Vice President of Legal and Chief Compliance Officer |
| Cathy Carew | Chief Organizational Effectiveness Officer |
| Nate Sanburn | Chief Business Officer |