Company Description
Alnylam Pharmaceuticals, Inc., a biopharmaceutical company, focuses on discovering, developing, and commercializing novel therapeutics based on ribonucleic acid interference.
Its marketed products include ONPATTRO (patisiran) for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis in adults; AMVUTTRA for the treatment of hATTR amyloidosis with polyneuropathy in adults; GIVLAARI for the treatment of adults with acute hepatic porphyria; and OXLUMO for the treatment of primary hyperoxaluria type 1.
In addition, the company develops patisiran for the treatment of transthyretin amyloidosis, or ATTR amyloidosis, with cardiomyopathy; cemdisiran to treat complement-mediated diseases; Belcesiran for the treatment of alpha-1 liver disease; Elebsiran to treat chronic HBV infection; Zilebesiran to treat hypertension; ALN-APP to treat Alzheimer’s disease and cerebral amyloid angiopathy; and ALN-HSD to treat NASH.
Further, it offers Fitusiran for the treatment of hemophilia, Inclisiran to treat hypercholesterolemia, lumasiran for the treatment of advanced PH1, and vutrisiran for the treatment of ATTR amyloidosis, which is in phase 3 clinical trial.
Alnylam Pharmaceuticals, Inc. has strategic collaborations with Regeneron Pharmaceuticals, Inc. to discover, develop, and commercialize RNAi therapeutics for a range of diseases by addressing therapeutic targets expressed in the eye and CNS; and Roche to develop pharmaceutical products containing zilebesiran.
It also has license and collaboration agreements with Novartis AG; Vir Biotechnology, Inc.; Dicerna Pharmaceuticals, Inc.; Ionis Pharmaceuticals, Inc.; and PeptiDream, Inc. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts.
| Country | United States |
| Founded | 2002 |
| IPO Date | May 28, 2004 |
| Industry | Biotechnology |
| Sector | Healthcare |
| Employees | 2,100 |
| CEO | Yvonne Greenstreet |
Contact Details
Address: 675 West Kendall Street, Henri A. Termeer Square Cambridge, Massachusetts 02142 United States | |
| Phone | 617 551 8200 |
| Website | alnylam.com |
Stock Details
| Ticker Symbol | ALNY |
| Exchange | NASDAQ |
| Fiscal Year | January - December |
| Reporting Currency | USD |
| CIK Code | 0001178670 |
| CUSIP Number | 02043Q107 |
| ISIN Number | US02043Q1076 |
| Employer ID | 77-0602661 |
| SIC Code | 2834 |
Key Executives
| Name | Position |
|---|---|
| Dr. Yvonne L. Greenstreet M.B.A., MBChB | Chief Executive Officer and Director |
| Jeffrey V. Poulton M.B.A. | Chief Financial Officer and Executive Vice President |
| Dr. Akshay K. Vaishnaw M.D., Ph.D. | Chief Innovation Officer and Member of the Scientific Advisory Board |
| Dr. Pushkal P. Garg M.D. | Chief Medical Officer |
| Tolga Tanguler M.B.A. | Executive Vice President and Chief Commercial Officer |
| Timothy J. Maines | Chief Technical Operations and Quality Officer |
| Dr. Kevin Joseph Fitzgerald Ph.D. | Senior Vice President, Head of Research and Chief Scientific Officer |
| Piyush Sharma J.D. | Chief Ethics and Compliance Officer |
| Robert W. Hesslein Esq., J.D. | Chief Legal Officer and Corporate Secretary |
| Christine Regan Lindenboom | Chief Corporate Communications Officer |
Latest SEC Filings
| Date | Type | Title |
|---|---|---|
| Nov 12, 2024 | SC 13G/A | [Amend] Statement of acquisition of beneficial ownership by individuals |
| Nov 8, 2024 | SC 13G/A | [Amend] Statement of acquisition of beneficial ownership by individuals |
| Oct 31, 2024 | 10-Q | Quarterly Report |
| Oct 31, 2024 | 8-K | Current Report |
| Sep 25, 2024 | UPLOAD | Filing |
| Aug 20, 2024 | 144 | Filing |
| Aug 12, 2024 | 144 | Filing |
| Aug 12, 2024 | SC 13G/A | [Amend] Statement of acquisition of beneficial ownership by individuals |
| Aug 12, 2024 | UPLOAD | Filing |
| Aug 6, 2024 | 144 | Filing |