Alnylam Pharmaceuticals Revenue by Segment

Period Ending	Dec 31, 2025	Sep 30, 2025	Jun 30, 2025	Mar 31, 2025	Dec 31, 2024	Sep 30, 2024	Jun 30, 2024	Mar 31, 2024	Mar 31, 2023	Dec 31, 2022	Sep 30, 2022	Jun 30, 2022	Mar 31, 2022	Dec 31, 2021	Sep 30, 2021	Jun 30, 2021	Mar 31, 2021	Dec 31, 2020	Sep 30, 2020
Amvuttra	2.31B	1.77B	1.35B	1.09B	970.41M	859.20M	749.30M	651.30M	-	-	-	-	-	-	-	-	-	-	-
Amvuttra Growth	138.44%	106.44%	79.78%	66.62%	73.94%	90.43%	128.65%	-	-	-	-	-	-	-	-	-	-	-	-
Collaboration	553.37M	619.37M	325.03M	490.83M	510.15M	479.60M	849.70M	628.20M
Collaboration Growth	8.47%	29.14%	-61.75%	-21.87%	-6.60%	-11.25%	497.54%	332.05%
Givlaari	308.49M	286.34M	283.46M	264.71M	255.85M	250.50M	233.60M	229.40M
Givlaari Growth	20.58%	14.31%	21.35%	15.39%	16.72%	21.01%	17.62%	23.40%
Oxlumo	191.44M	185.36M	172.73M	166.46M	166.97M	156.10M	144.60M	128.20M								-	-	-	-
Oxlumo Growth	14.65%	18.75%	19.46%	29.85%	52.07%	54.71%	63.21%	61.66%								-	-	-	-
Royalty	174.02M	148.04M	125.23M	107.65M	91.79M	73.40M	59.90M	44.70M						-	-	-	-	-	-
Royalty Growth	89.59%	101.68%	109.07%	140.83%	126.08%	179.09%	213.61%	214.79%						-	-	-	-	-	-
Onpattro	172.79M	197.21M	208.43M	233.09M	252.80M	275.70M	307.00M	321.30M
Onpattro Growth	-31.65%	-28.47%	-32.11%	-27.45%	-28.71%	-30.69%	-33.43%	-38.58%

Source: Business metrics provided by Main Street Data and sourced from official company press releases and documents.