Amylyx Pharmaceuticals, Inc. (AMLX)

NASDAQ: AMLX · Real-Time Price · USD
14.07
+0.39 (2.85%)
At close: May 27, 2026, 4:00 PM EDT
14.05
-0.02 (-0.14%)
After-hours: May 27, 2026, 7:32 PM EDT
Market Cap1.56B +280.7%
Revenue (ttm)n/a
Net Income-150.11M
EPS-1.49
Shares Out 111.19M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume580,248
Open13.91
Previous Close13.68
Day's Range13.74 - 14.25
52-Week Range4.64 - 18.61
Beta-0.10
AnalystsStrong Buy
Price Target23.40 (+66.31%)
Earnings DateMay 7, 2026

About AMLX

Amylyx Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, engages in the discovery and development of treatment options for neurodegenerative diseases and endocrine conditions in the United States. It provides Avexitide, an investigational, first-in-class glucagon-like peptide-1, or GLP-1 receptor antagonist, which is in phase 3 clinical trial to treat post-bariatric hypoglycemia and congenital hyperinsulinism. The company also develops AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol which is phas... [Read more]

Sector Healthcare
IPO Date Jan 7, 2022
Employees 136
Stock Exchange NASDAQ
Ticker Symbol AMLX
Full Company Profile

Financial Performance

Financial Statements

Analyst Summary

According to 12 analysts, the average rating for AMLX stock is "Strong Buy." The 12-month stock price target is $23.4, which is an increase of 66.31% from the latest price.

Price Target
$23.4
(66.31% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Amylyx announces publication of Phase 2 open-label HELIOS trial data

Amylyx (AMLX) Pharmaceuticals announced that Week 24 and Week 48 results from the Phase 2 open-label HELIOS clinical trial of AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taur...

12 days ago - TheFly

Amylyx Pharmaceuticals Announces Peer-Reviewed Publication of Phase 2 Open-Label HELIOS Trial Data for AMX0035 in The Journal of Clinical Investigation

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Amylyx Pharmaceuticals, Inc. (Nasdaq: AMLX) (“Amylyx” or the “Company”) today announced that Week 24 and Week 48 results from the Phase 2 open-label HELIOS clinical ...

12 days ago - Business Wire

Amylyx Pharmaceuticals Eyes Phase 3 AVEXITIDE Readout as 2027 Launch Comes Into Focus

Amylyx Pharmaceuticals NASDAQ: AMLX is preparing for a pivotal Phase 3 readout for AVEXITIDE, its lead asset for post-bariatric hypoglycemia, or PBH, with data from the LUCIDITY trial expected in the ...

13 days ago - MarketBeat

Amylyx Pharmaceuticals Transcript: Bank of America Global Healthcare Conference 2026

AVEXITIDE is nearing pivotal phase III data for PBH, with strong prior efficacy and minimal expected placebo effect. Commercial plans target 160,000 U.S. patients, with a 2027 launch anticipated and cash runway into 2028. Expansion includes a long-acting version and pipeline assets for rare diseases.

14 days ago - Transcripts

Amylyx sees cash runway into 2028

Cash, cash equivalents, and short-term investments were $279.8 million at March 31, 2026, compared to $317.0 million at December 31, 2025. Based on its current operating plans, Amylyx (AMLX) expects…

20 days ago - TheFly

Amylyx Pharmaceuticals Earnings Call Transcript: Q1 2026

Advanced pivotal LUCIDITY trial for avexitide in PBH, with top-line data expected next quarter and NDA preparations underway. Q1 operating expenses rose 16% year-over-year, with a strong cash position supporting a potential 2027 launch. Expanded access and commercial readiness efforts are progressing.

20 days ago - Transcripts

Amylyx Pharmaceuticals Earnings release: Q1 2026

Amylyx Pharmaceuticals released its Q1 2026 earnings on May 7, 2026, summarizing the period's financial results.

20 days ago - Filings

Amylyx Pharmaceuticals Quarterly report: Q1 2026

Amylyx Pharmaceuticals has published its Q1 2026 quarterly earnings report on May 7, 2026.

20 days ago - Filings

Amylyx Pharmaceuticals Reports First Quarter 2026 Financial Results

CAMBRIDGE, Mass.--(BUSINESS WIRE)---- $AMLX--Amylyx Pharmaceuticals Reports First Quarter 2026 Financial Results.

20 days ago - Business Wire

Amylyx Pharmaceuticals to Participate in Upcoming Investor Conferences

CAMBRIDGE, Mass.--(BUSINESS WIRE)---- $AMLX--Amylyx Pharmaceuticals to Participate in Upcoming Investor Conferences.

21 days ago - Business Wire

Amylyx announces launch of U.S. EAP for adults with PBH

Amylyx (AMLX) Pharmaceuticals announced the launch of a U.S. Expanded Access Program, EAP, for up to 250 adults with post-bariatric hypoglycemia, PBH, to provide treatment access to avexitide, an inve...

22 days ago - TheFly

Amylyx Pharmaceuticals Announces U.S. Expanded Access Program for Adults with Post-Bariatric Hypoglycemia

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Amylyx Pharmaceuticals, Inc. (Nasdaq: AMLX) (“Amylyx” or the “Company”) today announced the launch of a U.S. Expanded Access Program (EAP) for up to 250 adults with ...

22 days ago - Business Wire

Amylyx Pharmaceuticals to Report First Quarter 2026 Financial Results on May 7, 2026

CAMBRIDGE, Mass.--(BUSINESS WIRE)---- $AMLX--Amylyx Pharmaceuticals to Report First Quarter 2026 Financial Results on May 7, 2026.

27 days ago - Business Wire

Amylyx price target raised to $21 from $19 at Mizuho

Mizuho analyst Graig Suvannavejh raised the firm’s price target on Amylyx (AMLX) to $21 from $19 and keeps an Outperform rating on the shares ahead of the Q1 report. The…

4 weeks ago - TheFly

Amylyx Pharmaceuticals Proxy statement: Proxy filing

Amylyx Pharmaceuticals filed a proxy statement on April 23, 2026, providing details for shareholder voting and corporate governance matters.

4 weeks ago - Filings

Amylyx Pharmaceuticals Proxy statement: Proxy filing

Amylyx Pharmaceuticals filed a proxy statement on April 23, 2026, providing details for shareholder voting and corporate governance matters.

4 weeks ago - Filings

Amylyx Pharmaceuticals Transcript: 25th Annual Needham Virtual Healthcare Conference

Avexitide, a GLP-1 antagonist for post-bariatric hypoglycemia, is in phase III trials with results expected in Q3 2025. Prior studies showed a 64% reduction in severe hypoglycemic events, and the company is targeting a 2027 launch for this first-in-class therapy.

6 weeks ago - Transcripts

Did Amylyx Pharmaceuticals, Inc. Insiders Breach their Fiduciary Duties to Shareholders?

Shareholders are encouraged to contact the firm to discuss their rights and options at no cost or obligation. We would handle any matter on a contingent fee basis, whereby you would not be responsible...

6 weeks ago - PRNewsWire

Amylyx Pharmaceuticals to Present at the 25th Annual Needham Virtual Healthcare Conference

CAMBRIDGE, Mass.--(BUSINESS WIRE)---- $AMLX--Amylyx Pharmaceuticals to Present at the 25th Annual Needham Virtual Healthcare Conference.

7 weeks ago - Business Wire

Amylyx completes enrollment in Phase 3 Lucidity trial of avexitide

Amylyx (AMLX) Pharmaceuticals announced that the last participant has been randomized and dosed in the Phase 3 Lucidity clinical trial of avexitide. Lucidity is a 16-week, multicenter, randomized, dou...

2 months ago - TheFly

Amylyx Pharmaceuticals Announces Completion of Enrollment in Pivotal Phase 3 LUCIDITY Clinical Trial of Avexitide in Post-Bariatric Hypoglycemia

CAMBRIDGE, Mass.--(BUSINESS WIRE)---- $AMLX--Amylyx Pharmaceuticals Announces Completion of Enrollment in Pivotal Phase 3 LUCIDITY Clinical Trial of Avexitide in Post-Bariatric Hypoglycemia.

2 months ago - Business Wire

Amylyx price target raised to $30 from $25 at Guggenheim

Guggenheim analyst Seamus Fernandez raised the firm’s price target on Amylyx (AMLX) to $30 from $25 and keeps a Buy rating on the shares based on “high confidence” in a…

2 months ago - TheFly

Amylyx Pharmaceuticals Transcript: Leerink Global Healthcare Conference 2026

Avexitide, a GLP-1 receptor antagonist, is in a pivotal phase III trial for post-bariatric hypoglycemia, with prior studies showing strong efficacy and FDA breakthrough designation. Market research confirms a large orphan population, and future plans include label expansion and a long-acting formulation.

2 months ago - Transcripts

Amylyx price target raised to $34 from $28 at H.C. Wainwright

H.C. Wainwright analyst Andrew Fein raised the firm’s price target on Amylyx (AMLX) to $34 from $28 and keeps a Buy rating on the shares. Following recent engagement with institutional…

3 months ago - TheFly

Amylyx Pharmaceuticals Transcript: TD Cowen 46th Annual Health Care Conference

Top-line results from the pivotal avexitide phase III trial in PBH are expected in Q3 2026, with NDA submission and commercialization targeted for 2027. The pipeline includes ALS and Wolfram syndrome programs, and a long-acting GLP-1 antagonist is in early development.

3 months ago - Transcripts