Company Description
Arvinas, Inc., a clinical-stage biotechnology company, engages in the discovery, development, and commercialization of therapies to degrade disease-causing proteins.
The company engineers proteolysis targeting chimeras (PROTAC) targeted protein degraders that are designed to harness the body’s own natural protein disposal system to degrade and remove disease-causing proteins.
Its product pipeline includes Bavdegalutamide and ARV-766, investigational orally bioavailable PROTAC protein degraders for the treatment of men with metastatic castration-resistant prostate cancer, which are in Phase 3 clinical trials; and ARV-471, an orally bioavailable estrogen receptor degrading PROTAC targeted protein degrader for the treatment of patients with locally advanced or metastatic estrogen receptor+/human epidermal growth factor receptor 2-breast cancer, which is Phase 3 clinical trial.
The company’s products also consists ARV 393, orally bioavailable PROTAC designed to degrade BCL6, a transcriptional repressor and a key regulator of normal B-cell maturation and differentiation processes which is in Phase 1 first-in-human clinical trial; ARV 102 for the treatment of neurodegenerative diseases, which is in Phase 1 clinical trial; and KRAS G12D program is in preclinical development for pancreatic and colorectal cancers.
Arvinas, Inc. has collaborations with Pfizer Inc., Genentech, Inc., F. Hoffman-La Roche Ltd., Carrick Therapeutics Limited, and Bayer AG.
The company was founded in 2013 and is based in New Haven, Connecticut.
| Country | United States |
| Founded | 2015 |
| IPO Date | Sep 27, 2018 |
| Industry | Biotechnology |
| Sector | Healthcare |
| Employees | 430 |
| CEO | John Houston |
Contact Details
Address: 5 Science Park, 395 Winchester Avenue New Haven, Connecticut 06511 United States | |
| Phone | (203) 535-1456 |
| Website | arvinas.com |
Stock Details
| Ticker Symbol | ARVN |
| Exchange | NASDAQ |
| Stock Type | Common Stock |
| Fiscal Year | January - December |
| Reporting Currency | USD |
| CIK Code | 0001655759 |
| CUSIP Number | 04335A105 |
| ISIN Number | US04335A1051 |
| Employer ID | 47-2566120 |
| SIC Code | 2834 |
Key Executives
| Name | Position |
|---|---|
| Dr. John G. Houston Ph.D. | Chairperson, Chief Executive Officer and President |
| Dr. Ian Taylor Ph.D. | President of Research and Development and Chairman of Scientific Advisory Board |
| Andrew R. Saik | Chief Financial Officer and Treasurer |
| Angela M. Cacace Ph.D. | Chief Scientific Officer |
| Jared M. Freedberg J.D. | General Counsel and Corporate Secretary |
| Steve Weiss | Senior Vice President and Chief Human Resources Officer |
| Dr. Randy Teel Ph.D. | Chief Business Officer |
| Lisa Sinclair | Senior Vice President of Corporate Operations |
| Paul McInulty | Senior Vice President of Regulatory Affairs |
| Alexander A. Santini | Interim Chief Commercial Officer and Senior Vice President of Global and U.S. Market Access |
Latest SEC Filings
| Date | Type | Title |
|---|---|---|
| Feb 14, 2025 | SCHEDULE 13G/A | Filing |
| Feb 11, 2025 | S-8 | Securities to be offered to employees in employee benefit plans |
| Feb 11, 2025 | 10-K | Annual Report |
| Feb 11, 2025 | 8-K | Current Report |
| Jan 30, 2025 | SCHEDULE 13G | Filing |
| Jan 22, 2025 | 8-K | Current Report |
| Jan 10, 2025 | 8-K | Current Report |
| Jan 6, 2025 | 8-K | Current Report |
| Dec 16, 2024 | 8-K | Current Report |
| Dec 10, 2024 | 8-K | Current Report |