Fulcrum Therapeutics, Inc. (FULC)

Fulcrum Therapeutics Ratios and Metrics

Market cap in millions USD. Fiscal year is January - December.

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Mar 6, 2026	Dec 31, 2025	Dec 31, 2024	Dec 31, 2023	Dec 31, 2022	Dec 31, 2021
Market Cap	544	753	254	418	379	719
Market Cap Growth	162.02%	196.87%	-39.31%	10.19%	-47.23%	119.65%
Enterprise Value	198.26	404.74	19.07	190.34	187.18	500.52
Last Close Price	8.17	11.31	4.70	6.75	7.28	17.69
PE Ratio	-	-9.58	-29.37	-4.25	-2.98	-7.72
PS Ratio	-	-	3.17	148.99	59.80	37.50
PB Ratio	1.56	2.16	1.04	1.78	1.91	3.40
P/TBV Ratio	1.48	2.05	1.20	1.76	1.65	2.96
P/FCF Ratio	-	-12.47	-101.62	-4.57	-3.83	-8.96
P/OCF Ratio	-	-12.54	-114.36	-4.59	-3.91	-9.16
EV/Sales Ratio	-	-	0.24	67.86	29.51	26.12
EV/EBITDA Ratio	-	-4.85	-0.94	-1.75	-1.70	-6.37
EV/EBIT Ratio	-	-4.77	-0.87	-1.72	-1.66	-6.18
EV/FCF Ratio	-	-6.70	-7.64	-2.08	-1.89	-6.24
Debt / Equity Ratio	0.01	0.01	0.03	0.04	0.05	0
Debt / EBITDA Ratio	-0.08	-0.08	-0.42	-0.10	-0.12	-
Debt / FCF Ratio	-0.11	-0.11	-3.46	-0.12	-0.14	-
Net Debt / Equity Ratio	-0.99	-0.99	-0.96	-0.96	-0.95	-1.03
Net Debt / EBITDA Ratio	4.15	4.15	11.45	2.08	1.72	2.78
Net Debt / FCF Ratio	5.73	5.73	93.11	2.46	1.91	2.72
Asset Turnover	-	0	0.31	0.01	0.03	0.11
Quick Ratio	27.00	27.00	22.01	17.31	12.15	11.55
Current Ratio	27.40	27.40	22.63	17.71	12.41	11.77
Return on Equity (ROE)	-37.76%	-25.30%	-4.07%	-44.84%	-53.53%	-52.72%
Return on Assets (ROA)	-27.04%	-27.04%	-8.45%	-45.69%	-48.76%	-44.46%
Return on Invested Capital (ROIC)	-1196.20%	-1196.20%	-210.25%	-1076.24%	-1680.77%	-1992.48%
Return on Capital Employed (ROCE)	-28.12%	-28.12%	-8.87%	-48.75%	-52.88%	-50.87%
Earnings Yield	-13.76%	-10.43%	-3.40%	-23.56%	-33.52%	-12.95%
FCF Yield	-11.10%	-8.02%	-0.98%	-21.89%	-26.11%	-11.16%
Buyback Yield / Dilution	-22.40%	-22.40%	-1.08%	-28.26%	-22.23%	-25.95%

Updated Feb 24, 2026. Data Source: Fiscal.ai. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q