Karyopharm Therapeutics Inc. (KPTI)
NASDAQ: KPTI · Real-Time Price · USD
2.000
+0.070 (3.63%)
At close: Aug 19, 2026, 4:00 PM EDT
2.000
0.00 (0.00%)
After-hours: Aug 19, 2026, 6:14 PM EDT

Karyopharm Therapeutics Statistics

Total Valuation

KPTI has a market cap or net worth of $45.36 million. The enterprise value is $308.79 million.

Market Cap45.36M
Enterprise Value 308.79M

Important Dates

The last earnings date was Thursday, August 13, 2026, before market open.

Earnings Date Aug 13, 2026
Ex-Dividend Date n/a

Share Statistics

KPTI has 22.68 million shares outstanding. The number of shares has increased by 129.56% in one year.

Current Share Class 22.68M
Shares Outstanding 22.68M
Shares Change (YoY) +129.56%
Shares Change (QoQ) +17.09%
Owned by Insiders (%) 2.91%
Owned by Institutions (%) 78.27%
Float 17.07M

Valuation Ratios

PE Ratio n/a
Forward PE n/a
PS Ratio 0.30
Forward PS 0.31
PB Ratio n/a
P/TBV Ratio n/a
P/FCF Ratio n/a
P/OCF Ratio n/a
PEG Ratio n/a
Financial Ratio History

Enterprise Valuation

EV / Earnings n/a
EV / Sales 2.10
EV / EBITDA n/a
EV / EBIT n/a
EV / FCF n/a

Financial Position

The company has a current ratio of 0.79

Current Ratio 0.79
Quick Ratio 0.71
Debt / Equity n/a
Debt / EBITDA n/a
Debt / FCF n/a
Interest Coverage -1.67

Financial Efficiency

Return on Equity (ROE) n/a
Return on Assets (ROA) -47.61%
Return on Invested Capital (ROIC) -437.05%
Return on Capital Employed (ROCE) 359.36%
Weighted Average Cost of Capital (WACC) 11.58%
Revenue Per Employee $643,075
Profits Per Employee -$985,702
Employee Count228
Asset Turnover 1.36
Inventory Turnover 28.26

Taxes

Income Tax -32,000
Effective Tax Rate n/a

Stock Price Statistics

The stock price has decreased by -64.22% in the last 52 weeks. The beta is 0.95, so KPTI's price volatility has been similar to the market average.

Beta (5Y) 0.95
52-Week Price Change -64.22%
50-Day Moving Average 7.04
200-Day Moving Average 7.36
Relative Strength Index (RSI) 22.70
Average Volume (20 Days) 2,750,977

Short Selling Information

The latest short interest is 7.56 million, so 33.31% of the outstanding shares have been sold short.

Short Interest 7.56M
Short Previous Month 6.31M
Short % of Shares Out 33.31%
Short % of Float 44.27%
Short Ratio (days to cover) 4.48

Income Statement

In the last 12 months, KPTI had revenue of $146.62 million and -$224.74 million in losses. Loss per share was -$11.58.

Revenue146.62M
Gross Profit 19.63M
Operating Income -82.35M
Pretax Income -224.77M
Net Income -224.74M
EBITDA -82.20M
EBIT -82.35M
Loss Per Share -$11.58
Full Income Statement

Balance Sheet

The company has $65.11 million in cash and $328.53 million in debt, with a net cash position of -$263.43 million or -$11.61 per share.

Cash & Cash Equivalents 65.11M
Total Debt 328.53M
Net Cash -263.43M
Net Cash Per Share -$11.61
Equity (Book Value) -330.17M
Book Value Per Share -14.56
Working Capital -27.86M
Full Balance Sheet

Cash Flow

Operating Cash Flow -65.35M
Capital Expenditures n/a
Depreciation & Amortization 149,000
Net Borrowing 27.00M
Free Cash Flow -65.35M
FCF Per Share -$2.88
Full Cash Flow Statement

Margins

Gross margin is 13.39%, with operating and profit margins of -56.17% and -153.28%.

Gross Margin 13.39%
Operating Margin -56.17%
Pretax Margin -153.30%
Profit Margin -153.28%
EBITDA Margin -56.06%
EBIT Margin -56.17%
FCF Margin n/a

Dividends & Yields

KPTI does not appear to pay any dividends at this time.

Dividend Per Share n/a
Dividend Yield n/a
Dividend Growth (YoY) n/a
Years of Dividend Growth n/a
Payout Ratio n/a
Buyback Yield -129.56%
Shareholder Yield -129.56%
Earnings Yield -513.40%
FCF Yield -149.28%

Analyst Forecast

The average price target for KPTI is $7.25, which is 262.50% higher than the current price. The consensus rating is "Buy".

Price Target $7.25
Price Target Difference 262.50%
Analyst Consensus Buy
Analyst Count 5
Revenue Growth Forecast (3Y) 29.34%
EPS Growth Forecast (3Y) n/a
Stock Forecasts

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value n/a
Lynch Upside n/a
Graham Number n/a
Graham Upside n/a

Stock Splits

The last stock split was on February 26, 2025. It was a reverse split with a ratio of 1:15.

Last Split Date Feb 26, 2025
Split Type Reverse
Split Ratio 1:15

Scores

KPTI has an Altman Z-Score of -24.52 and a Piotroski F-Score of 3. A Z-score under 3 suggests an increased risk of bankruptcy.

Altman Z-Score -24.52
Piotroski F-Score 3