Karyopharm Therapeutics Inc. (KPTI)

Karyopharm Therapeutics Statistics

Total Valuation

KPTI has a market cap or net worth of $168.46 million. The enterprise value is $374.33 million.

Market Cap	168.46M
Enterprise Value	374.33M

Important Dates

The last earnings date was Thursday, May 14, 2026, before market open.

Earnings Date	May 14, 2026
Ex-Dividend Date	n/a

Share Statistics

KPTI has 22.55 million shares outstanding. The number of shares has increased by 72.20% in one year.

Current Share Class	22.55M
Shares Outstanding	22.55M
Shares Change (YoY)	+72.20%
Shares Change (QoQ)	+38.04%
Owned by Insiders (%)	0.62%
Owned by Institutions (%)	54.34%
Float	15.22M

Valuation Ratios

PE Ratio	n/a
Forward PE	n/a
PS Ratio	1.11
Forward PS	1.22
PB Ratio	n/a
P/TBV Ratio	n/a
P/FCF Ratio	n/a
P/OCF Ratio	n/a
PEG Ratio	n/a

Enterprise Valuation

EV / Earnings	n/a
EV / Sales	2.48
EV / EBITDA	n/a
EV / EBIT	n/a
EV / FCF	n/a

Financial Position

Current Ratio	n/a
Quick Ratio	n/a
Debt / Equity	n/a
Debt / EBITDA	n/a
Debt / FCF	n/a
Interest Coverage	-1.78

Financial Efficiency

Return on Equity (ROE)	n/a
Return on Assets (ROA)	-40.62%
Return on Invested Capital (ROIC)	-123.26%
Return on Capital Employed (ROCE)	n/a
Weighted Average Cost of Capital (WACC)	11.20%
Revenue Per Employee	$662,798
Profits Per Employee	-$855,127
Employee Count	228
Asset Turnover	1.17
Inventory Turnover	n/a

Taxes

In the past 12 months, KPTI has paid $8,000 in taxes.

Income Tax	8,000
Effective Tax Rate	n/a

Stock Price Statistics

The stock price has increased by +40.41% in the last 52 weeks. The beta is 0.81, so KPTI's price volatility has been lower than the market average.

Beta (5Y)	0.81
52-Week Price Change	+40.41%
50-Day Moving Average	7.89
200-Day Moving Average	6.92
Relative Strength Index (RSI)	39.65
Average Volume (20 Days)	433,224

Short Selling Information

The latest short interest is 5.29 million, so 23.47% of the outstanding shares have been sold short.

Short Interest	5.29M
Short Previous Month	5.72M
Short % of Shares Out	23.47%
Short % of Float	34.78%
Short Ratio (days to cover)	10.26

Income Statement

In the last 12 months, KPTI had revenue of $151.12 million and -$194.97 million in losses. Loss per share was -$14.19.

Revenue	151.12M
Gross Profit	19.51M
Operating Income	-84.21M
Pretax Income	-194.96M
Net Income	-194.97M
EBITDA	-83.92M
EBIT	-84.21M
Loss Per Share	-$14.19

Balance Sheet

The company has $90.85 million in cash and $296.73 million in debt, with a net cash position of -$205.88 million or -$9.13 per share.

Cash & Cash Equivalents	90.85M
Total Debt	296.73M
Net Cash	-205.88M
Net Cash Per Share	-$9.13
Equity (Book Value)	-265.65M
Book Value Per Share	-12.07
Working Capital	114.52M

Cash Flow

Operating Cash Flow	n/a
Capital Expenditures	n/a
Depreciation & Amortization	292,000
Net Borrowing	n/a
Free Cash Flow	n/a
FCF Per Share	n/a

Margins

Gross margin is 12.91%, with operating and profit margins of -55.73% and -129.02%.

Gross Margin	12.91%
Operating Margin	-55.73%
Pretax Margin	-129.01%
Profit Margin	-129.02%
EBITDA Margin	-55.53%
EBIT Margin	-55.73%
FCF Margin	n/a

Dividends & Yields

KPTI does not appear to pay any dividends at this time.

Dividend Per Share	n/a
Dividend Yield	n/a
Dividend Growth (YoY)	n/a
Years of Dividend Growth	n/a
Payout Ratio	n/a
Buyback Yield	-72.20%
Shareholder Yield	-72.20%
Earnings Yield	-115.74%
FCF Yield	n/a

Analyst Forecast

The average price target for KPTI is $13.50, which is 80.72% higher than the current price. The consensus rating is "Buy".

Price Target	$13.50
Price Target Difference	80.72%
Analyst Consensus	Buy
Analyst Count	7
Revenue Growth Forecast (5Y)	17.70%
EPS Growth Forecast (5Y)	n/a

Fair Value

There are several formulas that can be used to estimate the intrinsic value of a stock.

Lynch Fair Value	n/a
Lynch Upside	n/a
Graham Number	n/a
Graham Upside	n/a

Stock Splits

The last stock split was on February 26, 2025. It was a reverse split with a ratio of 1:15.

Last Split Date	Feb 26, 2025
Split Type	Reverse
Split Ratio	1:15

Scores

Altman Z-Score	n/a
Piotroski F-Score	2