Company Description
Nuvalent, Inc., a clinical stage biopharmaceutical company, engages in the development of therapies for patients with cancer.
Its lead product candidates are NVL-520, a novel ROS1-selective inhibitor to address the clinical challenges of emergent treatment resistance, central nervous system (CNS)-related adverse events, and brain metastases that may limit the use of ROS1 tyrosine kinase inhibitors (TKIs) for patients with ROS proto-oncogene 1 (ROS1)-positive non-small cell lung cancer (NSCLC) which is under the phase 2 portion of the ARROS-1 Phase 1/2 clinical trial; NVL-655, a brain-penetrant ALK-selective inhibitor, to address the clinical challenges of emergent treatment resistance, CNS-related adverse events, and brain metastases that might limit the use of first-, second-, and third-generation ALK inhibitors that is under the phase 2 portion of the ALKOVE-1 Phase 1/2 clinical trial; and NVL-330, a brain-penetrant human epidermal growth factor receptor 2 (HER2)-selective inhibitor designed to treat tumors driven by HER2ex20, brain metastases, and avoiding treatment-limiting adverse events including due to off-target inhibition of wild-type EGFR, which is expected to initiate phase 1 trial.
The company was incorporated in 2017 and is headquartered in Cambridge, Massachusetts.
Country | United States |
Founded | 2017 |
IPO Date | Jul 29, 2021 |
Industry | Biotechnology |
Sector | Healthcare |
Employees | 92 |
CEO | James Porter |
Contact Details
Address: One Broadway, 14th Floor Cambridge, Massachusetts 02142 United States | |
Phone | 857 357 7000 |
Website | nuvalent.com |
Stock Details
Ticker Symbol | NUVL |
Exchange | NASDAQ |
Fiscal Year | January - December |
Reporting Currency | USD |
IPO Price | $17.00 |
CIK Code | 0001861560 |
CUSIP Number | 670703107 |
ISIN Number | US6707031075 |
SIC Code | 2834 |
Key Executives
Name | Position |
---|---|
Dr. James R. Porter Ph.D. | Chief Executive Officer, President and Director |
Prof. Matthew D. Shair Ph.D. | Founder, Head of Scientific Advisory Board and Director |
Alexandra Balcom CPA, M.B.A. | Chief Financial Officer and Treasurer |
Dr. Christopher D. Turner M.D. | Chief Medical Officer |
Dr. Benjamin Lane Ph.D. | Senior Vice President of Technical Operations |
Henry Pelish Ph.D. | Chief Scientific Officer |
Deborah Ann Miller J.D., Ph.D. | Chief Legal Officer and Secretary |
Matthew Metivier | Senior Vice President of Human Resources |
Darlene Noci | Chief Development Officer |
John Soglia Ph.D. | Senior Vice President of Translational Development |
Latest SEC Filings
Date | Type | Title |
---|---|---|
Nov 12, 2024 | 10-Q | Quarterly Report |
Nov 12, 2024 | 8-K | Current Report |
Nov 8, 2024 | SC 13G | Statement of acquisition of beneficial ownership by individuals |
Oct 24, 2024 | SC 13G | Statement of acquisition of beneficial ownership by individuals |
Oct 22, 2024 | 144 | Filing |
Oct 22, 2024 | 144 | Filing |
Oct 15, 2024 | 144 | Filing |
Oct 1, 2024 | 144 | Filing |
Sep 30, 2024 | 144 | Filing |
Sep 17, 2024 | 8-K | Current Report |