Phio Pharmaceuticals Corp. (PHIO)

NASDAQ: PHIO · Real-Time Price · USD
1.140
+0.040 (3.64%)
At close: May 28, 2026, 4:00 PM EDT
1.139
-0.001 (-0.06%)
After-hours: May 28, 2026, 4:20 PM EDT
Market Cap13.24M +53.1%
Revenue (ttm)n/a
Net Income-10.93M
EPS-1.40
Shares Out 11.62M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume109,404
Open1.100
Previous Close1.100
Day's Range1.100 - 1.140
52-Week Range0.813 - 4.190
Beta0.84
AnalystsStrong Buy
Price Target14.00 (+1,150.0%)
Earnings DateMay 7, 2026

About PHIO

Phio Pharmaceuticals Corp., a clinical stage biopharmaceutical company, engages in the development of immuno-oncology therapeutics in the United States. It develops PH-762, an INTASYL compound designed to reduce the expression of PD-1 in multi-center Phase 1b dose-escalating clinical trials; PH-894, an INTASYL compound that is designed to specifically silence BRD4, a protein that controls gene expression in both T cells and tumor cells in preclinical studies. The company was formerly known as RXi Pharmaceuticals Corporation and changed its name... [Read more]

Industry Biotechnology
Sector Healthcare
Founded 2003
Employees 6
Stock Exchange NASDAQ
Ticker Symbol PHIO
Full Company Profile

Financial Performance

Financial Statements

Analyst Summary

According to one analyst, the rating for PHIO stock is "Strong Buy" and the 12-month stock price target is $14.0.

Price Target
$14.0
(1,150.00% upside)
Analyst Consensus: Strong Buy

News

Phio Pharmaceuticals Reports First Quarter 2026 Financial Results and Business Update

Completion of Lead Clinical Candidate PH-762 Dose Escalation Trial for Treatment of Skin Cancer with Favorable Safety and Pathology Data Key Development Agreements Secured for Nonclinical Toxicology a...

21 days ago - Newsfile Corp

Phio Pharmaceuticals Quarterly report: Q1 2026

Phio Pharmaceuticals has published its Q1 2026 quarterly earnings report on May 7, 2026.

21 days ago - Filings

Phio Pharmaceuticals Earnings release: Q1 2026

Phio Pharmaceuticals released its Q1 2026 earnings on May 7, 2026, summarizing the period's financial results.

21 days ago - Filings

Phio Pharmaceuticals Transcript: Fireside chat

The discussion highlighted a novel siRNA-based therapy for cutaneous squamous cell carcinoma, showing strong early clinical results and the potential to reduce reliance on surgery. The technology platform is adaptable to other cancers, with upcoming regulatory milestones and a focus on minimizing dilution risk for investors.

6 weeks ago - Transcripts

Phio Pharmaceuticals Transcript: Second Annual Centri Capital Conference

A novel RNA-based immunotherapy for skin cancer showed strong efficacy and safety in phase I-B trials, with plans to advance to phase II-B/III next year. The company is well-capitalized, focusing on high-value indications and out-licensing non-core assets.

6 weeks ago - Transcripts

Phio Pharmaceuticals Announces "Nobel Prize Winning Science Takes on Skin Cancer" in a Fireside Chat with Force Family Office on Wednesday, April 15, 2026

Phio invites investors, advisors and analysts with an interest in the life sciences sector to attend this virtual event R. Todd Plott, M.D.

6 weeks ago - Newsfile Corp

Phio Pharmaceuticals Announces Agreement with U.S. cGMP Manufacturing Source for Drug Product, PH-762

A Critical Next Step in Advancing Phio's PH-762 Program to Treat Cutaneous Carcinomas King of Prussia, Pennsylvania--(Newsfile Corp. - March 30, 2026) - Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is a ...

2 months ago - Newsfile Corp

Phio Pharmaceuticals Announces American Academy of Dermatology 2026 Presentation Featuring Clinical Study Results from Study of PH-762 for Cutaneous Carcinoma Underscoring Clinical Pipeline Advancement

Prestigious Late-Breaking Research Session Positions PH-762 as a Promising New PD-1 Directed Immunotherapy Candidate on March 28, 2026 at 3 PM (MDT) King of Prussia, Pennsylvania--(Newsfile Corp. - Ma...

2 months ago - Newsfile Corp

Phio Pharmaceuticals Announces "A Groundbreaking Approach to Treating Skin Cancer" in a Fireside Chat with Force Family Office

Registration link below for Wednesday March 18, 2026 at 4 PM EDT Phio invites individual and institutional investors, as well as advisors and analysts with an interest in the life sciences sector, to ...

2 months ago - Newsfile Corp

Phio Pharmaceuticals Transcript: Life Sciences Virtual Investor Forum

A novel RNA-based therapy for skin cancer demonstrated strong efficacy and safety in early trials, with 85% response at the highest dose and no toxicities. The company is preparing for pivotal studies, has a robust IP portfolio, and is exploring partnerships for broader applications.

2 months ago - Transcripts

Phio Pharmaceuticals to Present at the Life Sciences Investor Forum on March 12, 2026 11 AM EDT

The Company invites individual and institutional investors, as well as advisors and analysts with an interest in the life sciences sector, to attend live, interactive presentations at VirtualInvestorC...

2 months ago - GlobeNewsWire

Phio Pharmaceuticals to Present at the Life Sciences Investor Forum on March 12, 2026, 11 AM EDT

The Company invites individual and institutional investors, as well as advisors and analysts with an interest in the life sciences sector, to attend live, interactive presentations at VirtualInvestorC...

2 months ago - Newsfile Corp

Phio Pharmaceuticals Reports 2025 Year-End Financial Results and Business Update

Treatment Phase for Lead Clinical Candidate PH-762 Dose Escalation Trial is Complete with Favorable Safety, Tolerability and Pathology Data 2025 Financings and Warrant Exercises Strengthen Balance She...

2 months ago - Newsfile Corp

Phio Pharmaceuticals Annual report: Q4 2025

Phio Pharmaceuticals has published its Q4 2025 annual report on March 5, 2026.

2 months ago - Filings

Phio Pharmaceuticals Earnings release: Q4 2025

Phio Pharmaceuticals released its Q4 2025 earnings on March 5, 2026, summarizing the period's financial results.

2 months ago - Filings

Phio Pharmaceuticals Announces Participation in the Renmark Financial Communications Live Virtual Non-Deal Roadshow Series

Live Presentation and Q&A: Monday, March 9, 2026 10 AM EDT CEO to Discuss INTASYL Platform and PH-762 Phase 1b Results King of Prussia, Pennsylvania--(Newsfile Corp. - March 5, 2026) - Phio Pharmaceut...

3 months ago - Newsfile Corp

Phio Pharmaceuticals Slides: Corporate presentation

Phio Pharmaceuticals has posted slides in relation to its latest quarterly earnings report, which was published on February 24, 2026.

3 months ago - Filings

Phio Announces Safety Monitoring Committee's (SMC) Positive Wrap-up on Lead Clinical Candidate PH-762 in Skin Cancer Trial

Maximum Dose Concentration in Final Cohort Yields 85% Pathological Response (6 of 7 Patients); Complete Response (100% Tumor Clearance) in 4 of 6 Responders No Serious Adverse Events or Dose-Limiting ...

3 months ago - Newsfile Corp

Phio Pharmaceuticals Announces Participation in Third Annual DealFlow Discovery Conference

Phio's Presentation to take place on Wednesday January 28, 2026 at 9 AM ET King of Prussia, Pennsylvania--(Newsfile Corp. - January 26, 2026) - Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is a clinical-...

4 months ago - Newsfile Corp

Phio Pharmaceuticals Announces Key Tumor Response Data from all Cohorts in Intratumoral PH-762 Dose Escalation Cutaneous Carcinoma Trial

Pathology data indicate 70% overall response rate for squamous cell carcinomas: 100% clearance in 10 out of 14 responders Favorable safety and tolerability at all dose escalations King of Prussia, Pen...

4 months ago - Newsfile Corp

Phio Pharmaceuticals Announces Participation in the Sidoti Micro-Cap Virtual Investor Conference January 21-22, 2026

Registration Link for Phio's Presentation on Thursday, January 22 at 1:45 PM ET King of Prussia, Pennsylvania--(Newsfile Corp. - January 15, 2026) - Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is a clin...

4 months ago - Newsfile Corp

Phio Pharmaceuticals Announces Significant Step Forward in its Drug Development Program for PH-762

Nonclinical protocol study design accepted by FDA Study to commence in First Quarter 2026 King of Prussia, Pennsylvania--(Newsfile Corp. - December 23, 2025) - Phio Pharmaceuticals Corp. (NASDAQ: PHIO...

5 months ago - Newsfile Corp

Phio Pharmaceuticals Announces Completion of Enrollment in Phase 1b Clinical Trial of INTASYL siRNA Lead Compound PH-762

King of Prussia, Pennsylvania--(Newsfile Corp. - November 25, 2025) - Phio Pharmaceuticals Corp. (NASDAQ: PHIO) is a clinical-stage siRNA biopharmaceutical company developing therapeutics using its pr...

6 months ago - Newsfile Corp

Phio Pharmaceuticals files to sell 11.76M shares of common stock for holders

The company will not receive any of the proceeds from the sale by the selling stockholders of the shares of common stock.

6 months ago - TheFly

Phio Pharmaceuticals Registration statement: Registration Filing

Phio Pharmaceuticals filed a registration statement on November 20, 2025, providing details about a securities offering with the SEC.

6 months ago - Filings