PolyPid Ltd. (PYPD)

NASDAQ: PYPD · Real-Time Price · USD
4.840
-0.180 (-3.59%)
At close: May 26, 2026, 4:00 PM EDT
4.930
+0.090 (1.86%)
After-hours: May 26, 2026, 7:57 PM EDT
Market Cap92.36M +233.2%
Revenue (ttm)n/a
Net Income-33.63M
EPS-1.78
Shares Out 19.08M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume148,951
Open5.190
Previous Close5.020
Day's Range4.810 - 5.200
52-Week Range2.440 - 5.200
Beta1.41
AnalystsStrong Buy
Price Target12.25 (+153.1%)
Earnings DateMay 13, 2026

About PYPD

PolyPid Ltd., a biopharmaceutical company, developing targeted, locally administered, and prolonged-release therapeutics using its proprietary polymer-lipid encapsulation matrix (PLEX) technology to address unmet medical needs. Its lead product candidate is D-PLEX100, which is in a pivotal Phase 3 confirmatory trial for prevention of surgical site infections (SSIs) in patients undergoing abdominal colorectal surgery with large incisions. The company is also developing OncoPLEX, which is in preclinical stage for the treatment of intra-tumoral ca... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Jun 26, 2020
Employees 75
Stock Exchange NASDAQ
Ticker Symbol PYPD
Full Company Profile

Financial Performance

Financial Statements

Analyst Summary

According to 4 analysts, the average rating for PYPD stock is "Strong Buy." The 12-month stock price target is $12.25, which is an increase of 153.10% from the latest price.

Price Target
$12.25
(153.10% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

PolyPid to Participate in the Craig-Hallum 23rd Annual Institutional Investor Conference

PETACH TIKVA, Israel, May 20, 2026 (GLOBE NEWSWIRE) -- PolyPid Ltd. (Nasdaq: PYPD) (“PolyPid” or the “Company”), an innovative biopharmaceutical company dedicated to improving patient outcomes by elev...

6 days ago - GlobeNewsWire

PolyPid Q1 Earnings Call Highlights

PolyPid NASDAQ: PYPD said its first quarter marked a transition from late-stage clinical development toward regulatory submission and commercial preparation for D-PLEX100, its lead product candidate f...

13 days ago - MarketBeat

PolyPid reports Q1 EPS (35c), consensus (43c)

“The first quarter of 2026 marked an important transition for PolyPid (PYPD), as we moved from late-stage development to the final stage prior to drug approval, the regulatory review stage,…

13 days ago - TheFly

PolyPid Earnings Call Transcript: Q1 2026

Transitioned to final NDA submission for D-PLEX100, with U.S. partnership talks in late stages and European MAA submission planned for Q3 2026. Q1 net loss improved year-over-year, cash position strengthened by loan repayment, and clinical data supports product efficacy.

13 days ago - Transcripts

PolyPid Earnings release: Q1 2026

PolyPid released its Q1 2026 earnings on May 13, 2026, summarizing the period's financial results.

13 days ago - Filings

PolyPid Provides Corporate Update and Reports First Quarter 2026 Financial Results

Initiated NDA Submission to the FDA for D-PLEX₁₀₀ ; Completion Expected Imminently  U.S. Commercial Partnership Discussions in Late Stages Conference Call Scheduled for Today at 8:30 AM ET PETACH TIKV...

13 days ago - GlobeNewsWire

PolyPid to Report First Quarter 2026 Financial Results and Operational Highlights on May 13, 2026

PETACH TIKVA, Israel, May 06, 2026 (GLOBE NEWSWIRE) -- PolyPid Ltd. (Nasdaq: PYPD) ("PolyPid" or the "Company"), an innovative biopharmaceutical company dedicated to improving patient outcomes by elev...

20 days ago - GlobeNewsWire

PolyPid to Present Data from SHIELD II Phase 3 Trial Demonstrating Reduced Severity of Surgical Site Infection at Surgical Infection Society 2026 Annual Meeting

Analysis demonstrates statistically significant reduction in the severity of surgical wound infections, with potential to lower hospital resource utilization following abdominal colorectal surgery PET...

4 weeks ago - GlobeNewsWire

PolyPid to Present New Phase 3 SHIELD II Data Demonstrating D-PLEX₁₀₀ Sustained Local Release at ESCMID Global 2026

Analysis demonstrates D-PLEX₁₀₀ prolonged delivery mechanism ability to deliver continuous release of doxycycline for 30 days at the surgical incision site Analysis demonstrates D-PLEX₁₀₀ prolonged de...

6 weeks ago - GlobeNewsWire

PolyPid Initiates D-PLEX₁₀₀ NDA Submission to the FDA

PolyPid Submits First Modules as Part of Rolling NDA Review; Completion expected in Second Quarter of 2026  U.S. Commercialization Partnership Negotiations on Track PETACH TIKVA, Israel, March 31, 202...

2 months ago - GlobeNewsWire

PolyPid granted $4.3M waiver from FDA for D-Plex application

PolyPid (PYPD) announced that the FDA has granted a small business waiver of the Prescription Drug User Fee Act, or PDUFA, fee of approximately $4.3M for the New Drug Application,…

2 months ago - TheFly

PolyPid Receives PDUFA Fee Waiver from FDA for D-PLEX₁₀₀'s New Drug Application

FDA  Grants $4. 3 Million Small Business Waiver, Enabling Focus on Commercialization Preparations

2 months ago - GlobeNewsWire

PolyPid Transcript: The Citizens Life Sciences Conference 2026

D-PLEX₁₀₀ is nearing NDA submission, with robust Phase 3 data showing significant reductions in surgical site infections and related complications. Market entry will focus on colorectal surgery, with plans for broader expansion and a strong emphasis on hospital partnerships and pharmacoeconomic value.

2 months ago - Transcripts

PolyPid Announces Participation in Upcoming Investor Conferences

PETACH TIKVA, Israel, Feb. 25, 2026 (GLOBE NEWSWIRE) -- PolyPid Ltd. (Nasdaq: PYPD) (“PolyPid” or the “Company”), an innovative biopharmaceutical company dedicated to improving patient outcomes by ele...

3 months ago - GlobeNewsWire

PolyPid Earnings Call Transcript: Q4 2025

SHIELD II Phase III trial success and positive FDA feedback position D-PLEX100 for a rolling NDA submission in Q1 2026, with advanced U.S. partnership talks and a strengthened balance sheet. The company is transitioning to commercialization, introducing the Kynatrix platform, and expects cash to last into H2 2026.

3 months ago - Transcripts

PolyPid Annual report: Q4 2025

PolyPid has published its Q4 2025 annual report on February 11, 2026.

3 months ago - Filings

PolyPid Earnings release: Q4 2025

PolyPid released its Q4 2025 earnings on February 11, 2026, summarizing the period's financial results.

3 months ago - Filings

PolyPid Provides Corporate Update and Reports Fourth Quarter and Full-Year 2025 Financial Results

The Company is in Advanced Stage s of Commercial U.S. Partner ship Discussions for D-PLEX₁₀₀

3 months ago - GlobeNewsWire

PolyPid Slides: Investor presentation

PolyPid has posted slides in relation to its latest quarterly earnings report, which was published on February 11, 2026.

3 months ago - Filings

PolyPid to Report Fourth Quarter 2025 Financial Results and Operational Highlights on February 11, 2026

PETACH TIKVA, Israel, Jan. 28, 2026 (GLOBE NEWSWIRE) -- PolyPid Ltd. (Nasdaq: PYPD) ("PolyPid" or the "Company"), a late-stage biopharma company aiming to improve surgical outcomes, today announced th...

4 months ago - GlobeNewsWire

PolyPid Transcript: 2nd Annual Lytham Partners Healthcare Investor Summit

A novel drug delivery platform is advancing toward FDA approval, with D-PLEX 100 showing strong phase 3 results in reducing surgical site infections. Commercialization plans include a U.S. partnership, and financial resources are sufficient through 2026.

4 months ago - Transcripts

PolyPid appoints Story as Chairman of Board of Directors

PolyPid (PYPD) announced the appointment of Brooke Story as Chairman of the Board of Directors, effective as of December 11, 2025. Story brings over 25 years of leadership experience in…

5 months ago - TheFly

PolyPid Appoints Veteran MedTech Leader Brooke Story as Chairman of the Board of Directors

Appointment Enhances PolyPid's Strategic, Commercial and Transaction Capabilities Ahead of D-PLEX₁₀₀ New Drug Application Submission Appointment Enhances PolyPid's Strategic, Commercial and Transactio...

5 months ago - GlobeNewsWire

PolyPid Transcript: KOL Event

D-PLEX100, a novel local antibiotic delivery system, demonstrated a 60% reduction in surgical site infections and strong safety in a large phase 3 trial. Regulatory submission is planned for early 2026, with high anticipated adoption among surgeons and hospitals due to robust efficacy, safety, and economic benefits.

5 months ago - Transcripts

PolyPid receives pre-NDA meeting minutes for D-Plex supporting NDA submission

PolyPid (PYPD) announced that it has received a formal pre-New Drug Application, NDA, meeting minutes from the U.S. Food and Drug Administration, FDA, supporting the NDA submission of D-PLEX100, the…

6 months ago - TheFly