Company Description
Vigil Neuroscience, Inc., a clinical-stage biotechnology company, focuses on developing treatments for rare and common neurodegenerative diseases by restoring the vigilance of microglia, the sentinel immune cells of the brain.
Its lead candidate is VGL101(Iluzanebart), a human monoclonal antibody agonist targeting human triggering receptor expressed on myeloid cells 2 and is in a Phase 2 trial in patients with adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP), a rare and fatal neurodegenerative disease.
The company is also developing VG-3927, an orally-available small molecule TREM2 agonist to treat common neurodegenerative diseases associated with microglial dysfunction, with an initial focus on Alzheimer’s disease in genetically defined subpopulations, which is being evaluated in a Phase 1 clinical trial.
It has license agreement with Amgen Inc. to commercially develop, manufacture, use, distribute, and sell therapeutic products containing compounds that bind to TREM2.
The company was incorporated in 2020 and is headquartered in Watertown, Massachusetts.
| Country | United States |
| Founded | 2020 |
| IPO Date | Jan 7, 2022 |
| Industry | Biotechnology |
| Sector | Healthcare |
| Employees | 69 |
| CEO | Ivana Magovcevic-Liebisch |
Contact Details
Address: 100 Forge Road, Suite 700 Watertown, Massachusetts 02472 United States | |
| Phone | 857 254 4445 |
| Website | vigilneuro.com |
Stock Details
| Ticker Symbol | VIGL |
| Exchange | NASDAQ |
| Stock Type | Common Stock |
| Fiscal Year | January - December |
| Reporting Currency | USD |
| IPO Price | $14.00 |
| CIK Code | 0001827087 |
| CUSIP Number | 92673K108 |
| ISIN Number | US92673K1088 |
| SIC Code | 2836 |
Key Executives
| Name | Position |
|---|---|
| Dr. Ivana Magovcevic-Liebisch J.D., Ph.D. | President, Chief Executive Officer and Director |
| Jennifer Ziolkowski CPA | Chief Financial Officer |
| Dr. David Gray Ph.D. | Chief Scientific Officer |
| Sharon Morani | Senior Director of Facilities and Operations |
| Eric Brophy | Senior Manager of Information Technology |
| Leah Gibson | Vice President of Investor Relations and Corporate Communications |
| April Effort M.B.A., M.S. | Vice President and Head of Corporate Development |
| Evan A. Thackaberry DABT, Ph.D. | Senior Vice President and Head of Early Development |
| Christian Mirescu Ph.D. | Senior Vice President and Head of Neuroimmunology |
| Weeteck Yeo Ph.D. | Senior Vice President of Strategic Operations |
Latest SEC Filings
| Date | Type | Title |
|---|---|---|
| Mar 13, 2025 | S-8 | Securities to be offered to employees in employee benefit plans |
| Mar 13, 2025 | 10-K | Annual Report |
| Mar 13, 2025 | 8-K | Current Report |
| Feb 12, 2025 | SCHEDULE 13G/A | Filing |
| Jan 23, 2025 | 8-K | Current Report |
| Nov 14, 2024 | SC 13G/A | [Amend] Statement of acquisition of beneficial ownership by individuals |
| Nov 14, 2024 | SC 13G/A | [Amend] Statement of acquisition of beneficial ownership by individuals |
| Nov 7, 2024 | 10-Q | Quarterly Report |
| Nov 7, 2024 | 8-K | Current Report |
| Oct 9, 2024 | SC 13D/A | [Amend] General statement of acquisition of beneficial ownership |