Wave Life Sciences Ltd. (WVE)

NASDAQ: WVE · Real-Time Price · USD
6.42
+0.23 (3.72%)
At close: May 21, 2026, 4:00 PM EDT
6.42
0.00 (0.00%)
After-hours: May 21, 2026, 4:10 PM EDT
Market Cap1.24B +25.6%
Revenue (ttm)71.80M -31.6%
Net Income-183.59M
EPS-1.03
Shares Out 192.40M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume3,642,305
Open6.15
Previous Close6.19
Day's Range6.02 - 6.45
52-Week Range5.02 - 21.73
Beta-1.32
AnalystsStrong Buy
Price Target21.94 (+241.75%)
Earnings DateApr 28, 2026

About WVE

Wave Life Sciences Ltd., a clinical-stage biotechnology company, designs, develops, and commercializes ribonucleic acid (RNA) medicines through PRISM, a discovery and drug development platform. The company’s medicines platform, PRISM combines multiple modalities, chemistry innovation, and deep insights into human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. It is developing WVE-006, a GalNAc-conjugated RNA editing oligonucleotide for the treatment of alpha-1 antitrypsin deficiency; WVE-007, a GalNAc... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Nov 11, 2015
Employees 317
Stock Exchange NASDAQ
Ticker Symbol WVE
Full Company Profile

Financial Performance

In 2025, Wave Life Sciences's revenue was $42.73 million, a decrease of -60.55% compared to the previous year's $108.30 million. Losses were -$204.38 million, 110.7% more than in 2024.

Financial Statements

Analyst Summary

According to 16 analysts, the average rating for WVE stock is "Strong Buy." The 12-month stock price target is $21.94, which is an increase of 241.75% from the latest price.

Price Target
$21.94
(241.75% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Wave Life Sciences Transcript: RBC Capital Markets Global Healthcare Conference 2026

Key advances include progress in siRNA and RNA editing platforms, with promising clinical data for obesity and AATD. Monthly dosing regimens and biomarker-driven regulatory strategies are being pursued, while new studies target high BMI and cardiometabolic endpoints.

1 day ago - Transcripts

Wave Life Sciences price target raised to $14 from $13 at Wells Fargo

Wells Fargo raised the firm’s price target on Wave Life Sciences (WVE) to $14 from $13 and keeps an Overweight rating on the shares. The firm notes the WVE-007 update…

1 day ago - TheFly

Wave Life Sciences Supports AlphaDetect to Accelerate Detection of Alpha-1

The sponsorship helps expand proven strategies to consistently detect a genetic, irreversible, and progressive condition in patients with liver and/or lung disease. DURHAM, N.C.

2 days ago - PRNewsWire

Wave Life Sciences price target lowered to $13 from $18 at H.C. Wainwright

H.C. Wainwright lowered the firm’s price target on Wave Life Sciences (WVE) to $13 from $18 and keeps a Buy rating on the shares. WVE-006’s readout at the American Thoracic…

2 days ago - TheFly

Wave Life Sciences Transcript: Study update

RestorAATion-2 phase I/II data show WVE-006 achieves robust, durable Z-AAT reduction and wild-type M-AAT restoration, mimicking the protective MZ phenotype in PiZZ AATD. The therapy is safe, well-tolerated, and supports convenient monthly dosing, with dynamic AAT responses during inflammation.

2 days ago - Transcripts

Wave Life Sciences Press release: Study update

Wave Life Sciences issued a press release on May 18, 2026, disclosing material business information to investors.

2 days ago - Filings

Wave Life Sciences Slides: Study update

Wave Life Sciences has posted slides in relation to its latest quarterly earnings report, which was published on May 18, 2026.

2 days ago - Filings

Wave Life Sciences announces updated data from RestorAATion-2 trial of WVE-006

Wave Life Sciences (WVE) announced updated data from the ongoing RestorAATion-2 trial of WVE-006, its investigational, GalNAc-conjugated, subcutaneously delivered RNA editing oligonucleotide for alpha...

2 days ago - TheFly

Wave Life Sciences Announces Positive Update on RestorAATion-2 Trial: WVE-006 (GalNAc-RNA Editing) Achieves MZ-Like Phenotype Across Both Biweekly and Monthly Dosing

Data reinforce WVE-006's potential to address both lung and liver manifestations of AATD with a durable, convenient, and safe therapy capable of recapitulating the protective MZ-like phenotype with mo...

3 days ago - GlobeNewsWire

Wave Life Sciences to Present at 2026 RBC Capital Markets Global Healthcare Conference

CAMBRIDGE, Mass., May 13, 2026 (GLOBE NEWSWIRE) -- Wave Life Sciences Ltd.

8 days ago - GlobeNewsWire

Wave Life Sciences Proxy statement: Proxy filing

Wave Life Sciences filed a proxy statement on May 7, 2026, providing details for shareholder voting and corporate governance matters.

14 days ago - Filings

Wave Life Sciences price target lowered to $24 from $30 at Citi

Citi analyst Samantha Semenkow lowered the firm’s price target on Wave Life Sciences (WVE) to $24 from $30 and keeps a Buy rating on the shares.

17 days ago - TheFly

Wave Life Sciences Proxy statement: Proxy filing

Wave Life Sciences filed a proxy statement on May 1, 2026, providing details for shareholder voting and corporate governance matters.

20 days ago - Filings

Wave Life Sciences price target lowered to $43 from $52 at Canaccord

Canaccord lowered the firm’s price target on Wave Life Sciences (WVE) to $43 from $52 and keeps a Buy rating on the shares. The firm said headed into the next…

21 days ago - TheFly

Wave Life Sciences price target lowered to $19 from $21 at BofA

BofA analyst Alec Stranahan lowered the firm’s price target on Wave Life Sciences (WVE) to $19 from $21 and keeps a Buy rating on the shares. Following the Q1 report,…

22 days ago - TheFly

Wave Life Sciences assumed with a Buy at Truist

Truist assumed coverage of Wave Life Sciences (WVE) with a Buy rating and price target of $15, down from $50. The firm says the reduced price target reflects higher risk…

22 days ago - TheFly

Wave Life Sciences price target lowered to $36 from $39 at Clear Street

Clear Street lowered the firm’s price target on Wave Life Sciences (WVE) to $36 from $39 and keeps a Buy rating on the shares following the Q1 report. The firm…

23 days ago - TheFly

Wave Life Sciences Earnings Call Transcript: Q1 2026

Lead programs for obesity and AATD advanced with strong clinical data, including significant visceral fat loss and dynamic AAT restoration. Revenue surged year-over-year, cash runway extends into 2028, and multiple pivotal trials and regulatory milestones are expected in 2026.

23 days ago - Transcripts

Wave Life Sciences Earnings release: Q1 2026

Wave Life Sciences released its Q1 2026 earnings on April 28, 2026, summarizing the period's financial results.

23 days ago - Filings

Wave Life Sciences Quarterly report: Q1 2026

Wave Life Sciences has published its Q1 2026 quarterly earnings report on April 28, 2026.

23 days ago - Filings

Wave Life Sciences reports Q1 EPS (13c), consensus (31c)

Reports Q1 revenue $38.25M, consensus $7.92M. “We’re accelerating WVE-007 to the next stages of development following the improvements in body composition already observed in the Phase 1 portion of ou...

23 days ago - TheFly

Wave Life Sciences Reports First Quarter 2026 Financial Results and Provides Business Update

With recent FDA acceptance of the  Phase 2a multidose portion of INLIGHT trial of WVE-007 (INHBE GalNAc-siRNA) in individuals with higher BMI, with and without type 2 diabetes, this portion of the tri...

23 days ago - GlobeNewsWire

Wave Life Sciences First Quarter 2026 Financial Results Scheduled for April 28, 2026

CAMBRIDGE, Mass., April 22, 2026 (GLOBE NEWSWIRE) -- Wave Life Sciences Ltd. (Nasdaq: WVE), a clinical-stage biotechnology company focused on unlocking the broad potential of RNA medicines to transfor...

4 weeks ago - GlobeNewsWire

Wave Life Sciences announces hearing on proposed redomicilation

As previously announced, Wave Life Sciences (WVE) is seeking shareholders’ and Singapore High Court approvals in relation to a scheme of arrangement under Section 210 of the Companies Act 1967…

4 weeks ago - TheFly

Wave Life Sciences Announces Hearing on Proposed Redomiciliation to the United States

CAMBRIDGE, Mass., April 21, 2026 (GLOBE NEWSWIRE) -- As previously announced, Wave Life Sciences Ltd. (Nasdaq: WVE), a clinical-stage biotechnology company focused on unlocking the broad potential of ...

4 weeks ago - GlobeNewsWire