Wave Life Sciences Ltd. (WVE)

NASDAQ: WVE · Real-Time Price · USD
8.04
+0.03 (0.37%)
Nov 5, 2025, 4:00 PM EST - Market closed
0.37%
Market Cap1.28B
Revenue (ttm)93.95M
Net Income (ttm)-129.87M
Shares Out 159.23M
EPS (ttm)-0.84
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume1,981,713
Open8.00
Previous Close8.01
Day's Range7.70 - 8.07
52-Week Range5.28 - 16.74
Beta-1.74
AnalystsStrong Buy
Price Target20.69 (+157.34%)
Earnings DateNov 10, 2025

About WVE

Wave Life Sciences Ltd., a clinical-stage biotechnology company, designs, develops, and commercializes ribonucleic acid (RNA) medicines through PRISM, a discovery and drug development platform. The company’s RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation, and deep insights into human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. It is developing WVE-006, an RNA editing oligonucleotide for the treatment of alpha-1 antitrypsin deficiency; WVE-007, a GalNAc-conjugated ... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Nov 11, 2015
Employees 288
Stock Exchange NASDAQ
Ticker Symbol WVE
Full Company Profile

Financial Performance

In 2024, Wave Life Sciences's revenue was $108.30 million, a decrease of -4.42% compared to the previous year's $113.31 million. Losses were -$97.01 million, 68.7% more than in 2023.

Financial Statements

Analyst Summary

According to 13 analysts, the average rating for WVE stock is "Strong Buy." The 12-month stock price target is $20.69, which is an increase of 157.34% from the latest price.

Price Target
$20.69
(157.34% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Wave Life Sciences to Present Preclinical Data Supporting Therapeutic Potential of WVE-007 for Obesity at ObesityWeek® 2025

Presentation will highlight preclinical data supporting the potential of WVE-007 (INHBE GalNAc-siRNA) as a unique approach for the treatment of obesity designed to drive fat loss while preserving musc...

1 day ago - GlobeNewsWire

Wave Life Sciences Third Quarter 2025 Financial Results Scheduled for November 10, 2025

CAMBRIDGE, Mass., Nov. 04, 2025 (GLOBE NEWSWIRE) -- Wave Life Sciences Ltd.

1 day ago - GlobeNewsWire

Wave Life Sciences Ltd. (WVE) Spotlight on RNA Editing and RNAi: Pipeline and Clinical Advances in Oligonucleotide Therapeutics Transcript

Wave Life Sciences Ltd. ( WVE) Spotlight on RNA Editing and RNAi: Pipeline and Clinical Advances in Oligonucleotide Therapeutics October 29, 2025 10:00 AM EDT Company Participants Kate Rausch - Head ...

5 days ago - Seeking Alpha

Correcting and Replacing Wave Life Sciences Announced Positive Target Engagement Data from INLIGHT Clinical Trial of WVE-007 for Obesity During Annual Research Day

This press release corrects and replaces the company's press release issued today, 10/29, at 4:15 p.m. ET in order to correct a typographical error in the first sub-bullet under “WVE-007  (GalNAc-siRN...

7 days ago - GlobeNewsWire

Wave Life Sciences Announced Positive Target Engagement Data from INLIGHT Clinical Trial of WVE-007 for Obesity During Annual Research Day

Dose-dependent mean reductions of Activin E of up to 85% one month post single dose of WVE-007 in INLIGHT clinical trial, exceeding levels that led to weight loss in preclinical models; WVE-007 is gen...

7 days ago - GlobeNewsWire

Wave Life Sciences Announces Virtual Research Day on October 29th and Participation at Upcoming Investor Conferences

CAMBRIDGE, Mass., Sept. 18, 2025 (GLOBE NEWSWIRE) -- Wave Life Sciences Ltd. (Nasdaq: WVE), a clinical-stage biotechnology company focused on unlocking the broad potential of RNA medicines to transfor...

6 weeks ago - GlobeNewsWire

Wave Life Sciences Ltd. (WVE) Positive RestorAATion-2 Clinical Data Update Conference Transcript

Wave Life Sciences Ltd. (NASDAQ:WVE) Positive RestorAATion-2 Clinical Data Update Transcript Company Participants Kate Rausch - Head of Investor Relations Paul Bolno - President, CEO & Director Chris...

2 months ago - Seeking Alpha

Why Is GSK Partner Wave Life Sciences Stock Trading Lower On Wednesday?

Wave Life Sciences Ltd. WVE stock is trading lower on Wednesday after the company shared data from the ongoing Phase 1b/2a RestorAATion-2 Trial of WVE-006 in alpha-1 antitrypsin deficiency.

Other symbols: GSK
2 months ago - Benzinga

Wave Life Sciences Announces Positive Update from Ongoing RestorAATion-2 Trial of WVE-006 in Alpha-1 Antitrypsin Deficiency

Achieved durable production of serum AAT protein at levels associated with a lower risk of AATD liver and lung diseases following repeat 200 mg doses of WVE-006 (11.9 µM total AAT, 7.2 µM M-AAT)

2 months ago - GlobeNewsWire

Wave Life Sciences Ltd. (WVE) Q2 2025 Earnings Call Transcript

Wave Life Sciences Ltd. (NASDAQ:WVE) Q2 2025 Earnings Conference Call July 30, 2025 8:30 AM ET Company Participants Erik Ingelsson - Chief Scientific Officer Kate Rausch - Head of Investor Relations ...

3 months ago - Seeking Alpha

Wave Life Sciences Reports Second Quarter 2025 Financial Results and Provides Business Update

WVE-006, the leading GalNAc-RNA editing oligonucleotide designed to correct AAT protein and address both lung and liver manifestations of AATD, rapidly advancing in RestorAATion-2 study of AATD patien...

3 months ago - GlobeNewsWire

Wave Life Sciences Second Quarter 2025 Financial Results Scheduled for July 30, 2025

CAMBRIDGE, Mass., July 23, 2025 (GLOBE NEWSWIRE) -- Wave Life Sciences Ltd. (Nasdaq: WVE), a clinical-stage biotechnology company focused on unlocking the broad potential of RNA medicines to transform...

3 months ago - GlobeNewsWire

Wave Life Sciences: Upgrading Rating To Buy After Turbulent 10 Months

Wave Life Sciences Ltd. is an innovative biotech with soli data for its AATD, Huntington's, and DMD programs. Its share price is nevertheless down 44% year-to-date, potentially creating a buying oppor...

4 months ago - Seeking Alpha

Wave Life Sciences Announces Oral Presentation of Preclinical Data Supporting WVE-007's Mechanism (INHBE) to Reduce Fat, Preserve Muscle, and Induce Healthy Weight Loss at ADA's Annual Scientific Sessions

Presentation to highlight WVE-007 (INHBE GalNAc-siRNA) as a potential novel and unique obesity treatment leading to healthy weight loss and supporting preclinical data demonstrating potent and durable...

4 months ago - GlobeNewsWire

Wave Life Sciences to Present at 2025 Jefferies Global Healthcare Conference

CAMBRIDGE, Mass., May 29, 2025 (GLOBE NEWSWIRE) -- Wave Life Sciences Ltd.

5 months ago - GlobeNewsWire

Wave Life Sciences Announces Appointment of Dr. Christopher Wright as Chief Medical Officer

CAMBRIDGE, Mass., May 28, 2025 (GLOBE NEWSWIRE) -- Wave Life Sciences Ltd.

5 months ago - GlobeNewsWire

Wave Life Sciences Ltd. (WVE) Q1 2025 Earnings Call Transcript

Wave Life Sciences Ltd. (NASDAQ:WVE) Q1 2025 Earnings Conference Call May 8, 2025 8:30 AM ET Company Participants Kate Rausch - Vice President, Investor Relations & Corporate Affairs Paul Bolno - Pre...

6 months ago - Seeking Alpha

Wave Life Sciences Reports First Quarter 2025 Financial Results and Provides Business Update

Dosing complete in the first two cohorts of INLIGHT trial in obesity of WVE-007 (INHBE siRNA), designed to induce healthy weight loss by reducing fat without impacting muscle; clinical data on track f...

6 months ago - GlobeNewsWire

Wave Life Sciences First Quarter 2025 Financial Results Scheduled for May 8, 2025

CAMBRIDGE, Mass., May 01, 2025 (GLOBE NEWSWIRE) -- Wave Life Sciences Ltd. (Nasdaq: WVE), a clinical-stage biotechnology company focused on unlocking the broad potential of RNA medicines to transform ...

6 months ago - GlobeNewsWire

Wave Life Sciences: Potential For Accelerated Approval Pathway With WVE-N531

Wave Life Sciences Ltd. release of multi-dose data from the phase 1b/2a open-label RestorAAtion-2 study, using WVE-006 for AATD-related lung disease, expected in 2025. Positive results were achieved i...

7 months ago - Seeking Alpha

Wave Life Sciences Stock Jumps On Positive Data From Muscle Disorder Drug, Plans FDA Submission Next Year

Wave Life Sciences Ltd. WVE released data from the Phase 2 FORWARD-53 trial of WVE-N531, which is an exon-skipping oligonucleotide being investigated in boys with Duchenne muscular dystrophy (DMD) who...

8 months ago - Benzinga

Wave Life Sciences Announces Positive Data from FORWARD-53 Clinical Trial in DMD Including Significant Functional Benefit and Reversal of Muscle Damage after 48 Weeks of Dosing with WVE-N531

Statistically significant and clinically meaningful improvement of 3.8 seconds in Time-to-Rise vs. natural history with largest effect observed relative to any approved dystrophin restoration therapy ...

8 months ago - GlobeNewsWire

Wave Life Sciences Ltd. (WVE) Q4 2024 Earnings Call Transcript

Wave Life Sciences Ltd. (NASDAQ:WVE) Q4 2024 Earnings Conference Call March 4, 2025 8:30 AM ET Company Participants Kate Rausch - VP, IR & Corporate Affairs Paul Bolno - President & CEO Erik Ingelsso...

8 months ago - Seeking Alpha

Wave Life Sciences Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Business Update

Dosing underway in INLIGHT trial of WVE-007 in obesity with clinical data expected in 2H 2025; enrollment complete in first single dose cohort

8 months ago - GlobeNewsWire

Wave Life Sciences Fourth Quarter and Full Year 2024 Financial Results Scheduled for March 4, 2025

CAMBRIDGE, Mass., Feb. 25, 2025 (GLOBE NEWSWIRE) -- Wave Life Sciences Ltd. (Nasdaq: WVE), a clinical-stage biotechnology company focused on unlocking the broad potential of RNA medicines to transform...

9 months ago - GlobeNewsWire