Zymeworks Inc. (ZYME)

NASDAQ: ZYME · Real-Time Price · USD
23.90
+5.38 (29.05%)
At close: Nov 17, 2025, 4:00 PM EST
23.96
+0.06 (0.25%)
After-hours: Nov 17, 2025, 7:59 PM EST
29.05%
Market Cap1.79B
Revenue (ttm)134.48M
Net Income (ttm)-63.43M
Shares Out 74.84M
EPS (ttm)-0.84
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume11,163,527
Open24.00
Previous Close18.52
Day's Range22.55 - 26.19
52-Week Range9.03 - 26.19
Beta1.31
AnalystsStrong Buy
Price Target22.00 (-7.95%)
Earnings DateNov 6, 2025

About ZYME

Zymeworks Inc., a clinical-stage biotechnology company, discovers, develops, and commercializes biotherapeutics for the treatment of cancer, and autoimmune and inflammatory diseases (AIID). Its therapeutic platforms and fully integrated drug development engine provides the flexibility and compatibility to precisely engineer and develop highly differentiated antibody-based therapeutic candidates. The company’s platforms include Azymetric multispecific antibody platform; Drug Conjugate platform includes a suite of proprietary cytotoxins comprisin... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Apr 28, 2017
Employees 286
Stock Exchange NASDAQ
Ticker Symbol ZYME
Full Company Profile

Financial Performance

In 2024, Zymeworks's revenue was $76.30 million, an increase of 0.38% compared to the previous year's $76.01 million. Losses were -$122.70 million, 3.39% more than in 2023.

Financial Statements

Analyst Summary

According to 7 analysts, the average rating for ZYME stock is "Strong Buy." The 12-month stock price target is $22.0, which is a decrease of -7.95% from the latest price.

Price Target
$22.0
(-7.95% downside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Jazz Pharmaceuticals' And Zymeworks' Ziihera Success: A Pleasant Surprise

Jazz Pharmaceuticals plc and Zymeworks Inc. announced positive topline phase 3 results for Ziihera in HER2-positive gastroesophageal adenocarcinoma. Ziihera in combination with chemotherapy and in com...

Other symbols: JAZZ
9 hours ago - Seeking Alpha

Zymeworks Surges On Positive Ziihera Phase 3 Data: Expanding First-Line GEA Opportunity

Zymeworks Inc. (ZYME) surged after positive Phase 3 results for Ziihera in first-line HER2-positive gastroesophageal adenocarcinoma, expanding its FDA-approved indications. ZYME's partnership-driven m...

10 hours ago - Seeking Alpha

Zymeworks, Jazz Pharmaceuticals Stocks Climb On Robust Gastroesophageal Trial Outcomes And Upcoming Regulatory Plans

Zymeworks Inc. (NASDAQ: ZYME) stock is surging on Monday, with a session volume of 2.17 million, compared to an average volume of 728.75K, according to Benzinga Pro.

Other symbols: JAZZ
11 hours ago - Benzinga

Jazz Pharmaceuticals and Zymeworks Report Positive Cancer Treatment Results. The Stocks Soar.

The companies' drug Ziihera shows clinically meaningful benefits for patients with gastroesophageal adenocarcinoma.

Other symbols: JAZZ
15 hours ago - Barrons

Zymeworks Announces Positive HERIZON-GEA-01 Phase 3 Results Supporting Ziihera® (zanidatamab-hrii) as HER2-Targeted Agent-of-Choice and New Standard of Care in First-Line HER2-Positive Locally Advanced or Metastatic Gastroesophageal Adenocarcinoma

VANCOUVER, British Columbia, Nov. 17, 2025 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME) a clinical-stage biotechnology company developing a diverse pipeline of novel, multifunctional biotherapeut...

17 hours ago - GlobeNewsWire

Zymeworks Inc. (ZYME) Q3 2025 Earnings Call Transcript

Zymeworks Inc. ( ZYME) Q3 2025 Earnings Call November 6, 2025 4:30 PM EST Company Participants Shrinal Inamdar - Director of Investor Relations Leone Patterson - Executive VP and Chief Business & Fin...

10 days ago - Seeking Alpha

Zymeworks Provides Corporate Update and Reports Third Quarter 2025 Financial Results

Encouraging Phase 1 data on ZW191, an antibody-drug conjugate (ADC) targeting folate receptor-⍺ (FR⍺), presented at the AACR-NCI-EORTC Conference First patient dosed in Phase 1 clinical trial of ZW251...

11 days ago - GlobeNewsWire

Zymeworks Announces Participation in Upcoming Investor Conferences

VANCOUVER, British Columbia, Oct. 28, 2025 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a clinical-stage biotechnology company developing a diverse pipeline of novel, multifunctional biotherapeu...

20 days ago - GlobeNewsWire

Zymeworks Inc. (ZYME) Shareholder/Analyst Call Transcript

Zymeworks Inc. (NASDAQ:ZYME) Shareholder/Analyst Call October 23, 2025 3:30 PM EDT Company Participants Sabeen Mekan - Senior Vice President of Clinical Development Stuart Barnscher Conference Call P...

25 days ago - Seeking Alpha

Zymeworks Presents Initial Clinical Data from the Phase 1 trial of ZW191, an Antibody-Drug Conjugate Targeting Folate Receptor-⍺ at AACR-NCI-EORTC Conference

VANCOUVER, British Columbia, Oct. 23, 2025 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a clinical-stage biotechnology company developing a diverse pipeline of novel, multifunctional biotherapeu...

25 days ago - GlobeNewsWire

Zymeworks to Report Third Quarter 2025 Financial Results and Host Conference Call on November 6, 2025

VANCOUVER, British Columbia, Oct. 16, 2025 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a clinical-stage biotechnology company developing a diverse pipeline of novel, multifunctional biotherapeu...

4 weeks ago - GlobeNewsWire

Zymeworks to Present Clinical Data from the Phase 1 trial of ZW191, an Antibody-Drug Conjugate Targeting Folate Receptor-⍺, at AACR-NCI-EORTC International Conference

Preliminary data presented at the AACR-NCI-EORTC conference will provide insights into the potential of ZW191 in patients with advanced solid tumors, including ovarian cancer, endometrial cancer, and ...

5 weeks ago - GlobeNewsWire

InMed Pharmaceuticals Appoints Mr. Neil Klompas to It's Board of Directors

Vancouver, British Columbia--(Newsfile Corp. - October 9, 2025) - InMed Pharmaceuticals Inc. (NASDAQ: INM) ("InMed" or the "Company"), a pharmaceutical company focused on developing a pipeline of prop...

Other symbols: INM
5 weeks ago - Newsfile Corp

Zymeworks Appoints Dr. Adam Schayowitz as Acting Chief Development Officer

VANCOUVER, British Columbia, Oct. 09, 2025 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a clinical-stage biotechnology company developing a diverse pipeline of novel, multifunctional biotherapeu...

5 weeks ago - GlobeNewsWire

Zymeworks: Despite T-Cell Engager Setback, ADC Candidates Press On

I maintain my Strong Buy rating on Zymeworks Inc., driven by its robust ADC pipeline and upcoming pivotal zanidatamab data in late 2025. ZW171 was discontinued due to on-target off-tumor toxicity, but...

2 months ago - Seeking Alpha

Zymeworks Pulls Plug On Early-Stage Cancer Potential As Therapy Unlikely To Provide Benefit

Zymeworks Inc. ZYME on Tuesday decided to voluntarily discontinue clinical development of ZW171, a T-cell engager designed to target gynecological, thoracic, and digestive system cancers.

2 months ago - Benzinga

Zymeworks halts development of cancer drug after trial setback

Zymeworks said on Tuesday it will stop developing its experimental cancer drug after results from a trial showed the treatment was unlikely to meet the company's goals as a standalone therapy.

2 months ago - Reuters

Zymeworks Announces Decision to Discontinue Clinical Development of ZW171, a Mesothelin-directed T cell Engager

VANCOUVER, British Columbia, Sept. 02, 2025 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a clinical-stage biotechnology company developing a diverse pipeline of novel, multifunctional biotherape...

2 months ago - GlobeNewsWire

Zymeworks Strengthens Board of Directors with Appointments of Greg Ciongoli and Robert E. Landry

VANCOUVER, British Columbia, Aug. 11, 2025 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a clinical-stage biotechnology company developing a diverse pipeline of novel, multifunctional biotherapeu...

3 months ago - GlobeNewsWire

Zymeworks Inc. (ZYME) Q2 2025 Earnings Call Transcript

Zymeworks Inc. (NASDAQ:ZYME) Q2 2025 Earnings Conference Call August 7, 2025 4:30 PM ET Company Participants Kenneth H. Galbraith - Chairman of the Board, CEO & President Leone D.

3 months ago - Seeking Alpha

Zymeworks Provides Corporate Update and Reports Second Quarter 2025 Financial Results

VANCOUVER, British Columbia, Aug. 07, 2025 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a clinical-stage biotechnology company developing a diverse pipeline of novel, multifunctional biotherapeu...

3 months ago - GlobeNewsWire

Zymeworks Announces FDA Clearance of Investigational New Drug Application for ZW251, a Novel Glypican 3-Targeted Topoisomerase 1 Inhibitor Antibody-Drug Conjugate

VANCOUVER, British Columbia, July 28, 2025 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a clinical-stage biotechnology company developing a diverse pipeline of novel, multifunctional biotherapeu...

4 months ago - GlobeNewsWire

Zymeworks to Report Second Quarter 2025 Financial Results and Host Conference Call on August 7, 2025

VANCOUVER, British Columbia, July 17, 2025 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a clinical-stage biotechnology company developing a diverse pipeline of novel, multifunctional biotherapeu...

4 months ago - GlobeNewsWire

Zymeworks: Early-Stage Biotech Feel Despite Zanidatamab Advancements (Downgrade)

Zymeworks Inc.'s lead asset zanidatamab won FDA approval for HER2-positive biliary tract cancer, validating its platform but addressing a small market. The main investment thesis hinges on upcoming Ph...

5 months ago - Seeking Alpha

Zymeworks Announces NMPA Approval of Zanidatamab in China for Adults with Previously Treated, Unresectable or Metastatic HER2-high expression (IHC3+) Biliary Tract Cancer

VANCOUVER, British Columbia, May 30, 2025 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a clinical-stage biotechnology company developing a diverse pipeline of novel, multifunctional biotherapeut...

6 months ago - GlobeNewsWire