Zymeworks Inc. (ZYME)

NASDAQ: ZYME · Real-Time Price · USD
22.88
-0.35 (-1.51%)
At close: Mar 13, 2026, 4:00 PM EDT
22.26
-0.62 (-2.71%)
After-hours: Mar 13, 2026, 4:17 PM EDT
Market Cap1.69B +76.8%
Revenue (ttm)105.97M +38.9%
Net Income-81.13M
EPS-1.08
Shares Out 73.75M
PE Ration/a
Forward PE18.66
Dividendn/a
Ex-Dividend Daten/a
Volume787,220
Open23.42
Previous Close23.23
Day's Range22.43 - 23.89
52-Week Range9.03 - 28.49
Beta1.28
AnalystsStrong Buy
Price Target38.90 (+70.02%)
Earnings DateMar 2, 2026

About ZYME

Zymeworks Inc., a biotechnology company, develops biotherapeutics for the treatment of cancer, inflammation, and autoimmune diseases. The company’s platforms include Azymetric multispecific antibody platform; Drug Conjugate platform that includes a suite of proprietary cytotoxins comprising topoisomerase and microtubulin inhibiting toxins, stable linkers, and conjugation technologies; EFECT platform, which consists of a set of modifications to the Fc region of antibodies; and ProTECT, a tumor-specific immune co-stimulation platform. Its lead pr... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Apr 28, 2017
Employees 264
Stock Exchange NASDAQ
Ticker Symbol ZYME
Full Company Profile

Financial Performance

In 2025, Zymeworks's revenue was $105.97 million, an increase of 38.87% compared to the previous year's $76.30 million. Losses were -$81.13 million, -33.88% less than in 2024.

Financial Statements

Analyst Summary

According to 11 analysts, the average rating for ZYME stock is "Strong Buy." The 12-month stock price target is $38.9, which is an increase of 70.02% from the latest price.

Price Target
$38.9
(70.02% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Zymeworks FY25 Review: From Milestone Volatility To 2026 Upside

Zymeworks Inc. (ZYME) reported weak Q4 results, highlighting the volatility of its milestone-driven revenue model and underscoring execution risk ahead of commercialization. Despite top-line misses, Z...

10 days ago - Seeking Alpha

Zymeworks Inc. (ZYME) Q4 2025 Earnings Call Transcript

Zymeworks Inc. (ZYME) Q4 2025 Earnings Call Transcript

11 days ago - Seeking Alpha

Zymeworks and Royalty Pharma Enter into $250 Million Royalty-Backed Note Financing

VANCOUVER, British Columbia and NEW YORK, March 02, 2026 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME) and Royalty Pharma plc (Nasdaq: RPRX) today announced an agreement for $250 million in fundin...

12 days ago - GlobeNewsWire

Zymeworks Provides Corporate Update and Reports Fourth Quarter and Full Year 2025 Financial Results

VANCOUVER, British Columbia, March 02, 2026 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a biotechnology company managing a portfolio of licensed healthcare assets, while developing a diverse pi...

12 days ago - GlobeNewsWire

Zymeworks To Report Fourth Quarter and Full Year 2025 Financial Results and Host Conference Call on March 2, 2026

VANCOUVER, British Columbia, Feb. 12, 2026 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a biotechnology company managing a portfolio of licensed healthcare assets, while developing a diverse pip...

4 weeks ago - GlobeNewsWire

Zymeworks Announces Participation in Upcoming Investor Conferences

VANCOUVER, British Columbia, Jan. 27, 2026 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a biotechnology company managing a portfolio of licensed healthcare assets, while developing a diverse pip...

6 weeks ago - GlobeNewsWire

Zymeworks Inc. (ZYME) Presents at 44th Annual J.P. Morgan Healthcare Conference Transcript

Zymeworks Inc. (ZYME) Presents at 44th Annual J.P. Morgan Healthcare Conference Transcript

2 months ago - Seeking Alpha

Zymeworks Announces Leadership Appointments and Transitions to Align with Evolution of Corporate Strategy

VANCOUVER, British Columbia, Jan. 12, 2026 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a biotechnology company managing a portfolio of licensed healthcare assets, while developing a diverse pip...

2 months ago - GlobeNewsWire

HERIZON-GEA-01 Trial Highlights Zymeworks' Path To $440M Milestones And Growth

Zymeworks delivered strong Phase 3 HERIZON-GEA-01 results for Ziihera, achieving over two years median overall survival in HER2-positive GEA. ZYME stands to receive up to $440 million in milestone pay...

2 months ago - Seeking Alpha

Zymeworks Outlines Strategic Priorities and Outlook for 2026

VANCOUVER, British Columbia, Jan. 11, 2026 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a biotechnology company managing a portfolio of licensed healthcare assets, while developing a diverse pip...

2 months ago - GlobeNewsWire

Ziihera® (zanidatamab-hrii) Combinations Achieve Unprecedented Results in First-Line HER2+ Locally Advanced or Metastatic GEA including more than Two Years Median Overall Survival Benefit

VANCOUVER, British Columbia, Jan. 06, 2026 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a biotechnology company managing a portfolio of licensed healthcare assets, while developing a diverse pip...

2 months ago - GlobeNewsWire

Zymeworks Inc. (ZYME) Presents at Citi Annual Global Healthcare Conference 2025 Transcript

Zymeworks Inc. (ZYME) Presents at Citi Annual Global Healthcare Conference 2025 Transcript

3 months ago - Seeking Alpha

Zymeworks Announces Participation in Upcoming Conferences

• Late-breaking HERIZON-GEA-01 presentation at ASCO GI highlights the expanding clinical profile of Ziihera ® across HER2-driven gastrointestinal cancers by partner Jazz • Zymeworks to present a Trial...

3 months ago - GlobeNewsWire

Zymeworks: Adjusting My Levels After Ziihera's Phase III Data For GEA

Zymeworks is gaining momentum as Ziihera shows strong Phase III data in HER2+ gastroesophageal adenocarcinoma, supporting growth and de-risking the investment. ZYME's royalty-based business model with...

4 months ago - Seeking Alpha

Zymeworks: A Lot Of Moving Parts

This article revisits Zymeworks Inc. following significant new trial data released this week. This triggered a 30% rally in ZYME stock on Monday, even as most of any future revenues will accrue to par...

4 months ago - Seeking Alpha

Zymeworks Inc. (ZYME) Shareholder/Analyst Call Transcript

Zymeworks Inc. ( ZYME) Shareholder/Analyst Call November 18, 2025 8:30 AM EST Company Participants Shrinal Inamdar - Director of Investor Relations Kenneth Galbraith - Chairman of the Board, CEO & Pr...

4 months ago - Seeking Alpha

Zymeworks Appoints Scott Platshon as Acting Chief Investment Officer

VANCOUVER, British Columbia, Nov. 18, 2025 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME), a biotechnology company managing a portfolio of licensed healthcare assets, while developing a diverse pip...

4 months ago - GlobeNewsWire

Zymeworks Announces Strategic Initiative to Optimize Value of Licensed Products by Building a Diversified Portfolio of Revenue-Generating Assets

VANCOUVER, British Columbia, Nov. 18, 2025 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME) a biotechnology company managing a portfolio of licensed healthcare assets, while developing a diverse pipe...

4 months ago - GlobeNewsWire

Jazz Pharmaceuticals' And Zymeworks' Ziihera Success: A Pleasant Surprise

Jazz Pharmaceuticals plc and Zymeworks Inc. announced positive topline phase 3 results for Ziihera in HER2-positive gastroesophageal adenocarcinoma. Ziihera in combination with chemotherapy and in com...

Other symbols: JAZZ
4 months ago - Seeking Alpha

Zymeworks Surges On Positive Ziihera Phase 3 Data: Expanding First-Line GEA Opportunity

Zymeworks Inc. (ZYME) surged after positive Phase 3 results for Ziihera in first-line HER2-positive gastroesophageal adenocarcinoma, expanding its FDA-approved indications. ZYME's partnership-driven m...

4 months ago - Seeking Alpha

Zymeworks, Jazz Pharmaceuticals Stocks Climb On Robust Gastroesophageal Trial Outcomes And Upcoming Regulatory Plans

Zymeworks Inc. (NASDAQ: ZYME) stock is surging on Monday, with a session volume of 2.17 million, compared to an average volume of 728.75K, according to Benzinga Pro.

Other symbols: JAZZ
4 months ago - Benzinga

Jazz Pharmaceuticals and Zymeworks Report Positive Cancer Treatment Results. The Stocks Soar.

The companies' drug Ziihera shows clinically meaningful benefits for patients with gastroesophageal adenocarcinoma.

Other symbols: JAZZ
4 months ago - Barrons

Zymeworks Announces Positive HERIZON-GEA-01 Phase 3 Results Supporting Ziihera® (zanidatamab-hrii) as HER2-Targeted Agent-of-Choice and New Standard of Care in First-Line HER2-Positive Locally Advanced or Metastatic Gastroesophageal Adenocarcinoma

VANCOUVER, British Columbia, Nov. 17, 2025 (GLOBE NEWSWIRE) -- Zymeworks Inc. (Nasdaq: ZYME) a clinical-stage biotechnology company developing a diverse pipeline of novel, multifunctional biotherapeut...

4 months ago - GlobeNewsWire

Zymeworks Inc. (ZYME) Q3 2025 Earnings Call Transcript

Zymeworks Inc. ( ZYME) Q3 2025 Earnings Call November 6, 2025 4:30 PM EST Company Participants Shrinal Inamdar - Director of Investor Relations Leone Patterson - Executive VP and Chief Business & Fin...

4 months ago - Seeking Alpha

Zymeworks Provides Corporate Update and Reports Third Quarter 2025 Financial Results

Encouraging Phase 1 data on ZW191, an antibody-drug conjugate (ADC) targeting folate receptor-⍺ (FR⍺), presented at the AACR-NCI-EORTC Conference First patient dosed in Phase 1 clinical trial of ZW251...

4 months ago - GlobeNewsWire