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Soufflé Therapeutics Stock

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Valuation$506.77M1
Valuation DateOct 13, 2026
Implied Valuationn/a
Last Pricen/a
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52-Week Lown/a
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3-Year Returnn/a
Total Funding$417.5M
Latest Round Amount$135M2
Latest RoundSeries B
Funding Rounds3
IPO StatusUnknown
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About Soufflé Therapeutics

Soufflé Therapeutics is a biotechnology company that develops siRNA medicines designed to reach specific cell types outside the liver. Its REMEDY (Receptor Mediated Delivery) platform identifies receptors that pull molecules into a target cell and pairs them with antibodies or other binders that carry an siRNA payload to silence a disease-causing gene. The lead candidate, SFL-0821, targets the DUX4 gene in skeletal muscle and entered a Phase 1/2 trial for facioscapulohumeral muscular dystrophy (FSHD) in 2026. Other programs target the phospholamban gene in heart muscle cells for heart failure and an undisclosed target for muscle and metabolic disorders. The company has no approved products and makes money through collaboration and licensing deals with drugmakers, including a 2026 global licensing agreement with Bayer for a heart-targeted siRNA therapy. It was co-founded by MIT professors Robert Langer and Daniel Anderson together with former Alnylam research head Victor Kotelianski.

Founded 2021
Country United States
CEO Amir Nashat
Founders Robert Langer, Daniel Anderson, Victor Kotelianski, Brad Pentelute, Marino Zerial, Amir Nashat
Headquarters Watertown, MA

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News

Soufflé Therapeutics raises $135M Series B

The Watertown-based RNA therapies developer closed a $135 million Series B round led by Juvia Group.

9 days ago - Boston Business Journal

Soufflé gets $135M for three RNA medicines

Endpoints News reported the Oct. 2026 Series B for the Bob Langer-affiliated oligonucleotide startup advancing three experimental programs.

10 days ago - Endpoints News

Soufflé Therapeutics Announces Oversubscribed $135 Million Series B Financing to Advance Lead Clinical Programs and Continued Pipeline Progress

Soufflé closed a $135 million Series B led by Juvia Group, with new investors including TCGX, BB Biotech, Fidelity and Balyasny, to fund clinical studies in FSHD, heart failure and muscle and metaboli...

10 days ago - Soufflé Therapeutics

Bayer and Soufflé Therapeutics Announce Strategic Collaboration to Advance Cell-Specific Heart-Targeted siRNA Therapy

BERLIN & BOSTON--(BUSINESS WIRE)--Bayer and Soufflé Therapeutics™, an innovative biotech company that discovers and develops cell-selective genetic therapies, today announced a strategic collaboration...

9 months ago - Business Wire

Soufflé Therapeutics Gets Venture, Pharma Backing for Genetic Medicines

The biotech startup emerged from stealth after raising nearly $200 million in venture money and said it plans clinical trials for a muscular dystrophy treatment the following year.

1 year ago - The Wall Street Journal

Langer family RNA biotech Soufflé rises with $200M and Big Pharma partners

Soufflé, co-founded by Robert Langer, launched with a $200 million Series A and partners including AbbVie, Amgen, Bayer and Novo Nordisk.

1 year ago - Fierce Biotech