Opus Genetics, Inc. (FRA:R3X1)
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1.706
-0.096 (-5.33%)
At close: Dec 1, 2025

Opus Genetics Company Description

Opus Genetics, Inc., a clinical-stage ophthalmic biopharmaceutical company, focuses on developing and commercializing therapies for the treatment of inherited retinal diseases (IRDs).

It develops OPGx-LCA5, an early-onset retinal degeneration that is in Phase 1/2 clinical trial for the treatment of LCA5-associated IRD; and OPGx-BEST1 to treat BEST1-associated retinal disease.

The company also develops various pre-clinical IRD programs, including OPGx-RHO, a gene therapy that targets autosomal dominant retinitis pigmentosa caused by RHO mutations; OPGx-RDH12 that is designed to restore protein expression and halt functional deterioration in patients with retinal dystrophy caused by mutations in the retinal dehydrogenase gene; OPGx-MERTK, an AAV vector for the treatment of MERTK IRD; OPGx-NMNAT1, a gene augmentation therapy designed to halt functional deterioration in pediatric patients with retinal degenerative disease caused by mutations in the nicotinamide mononucleotide adenylyltransferase 1 gene; and OPGx-CNGB1, an AAV gene therapy for retinitis pigmentosa due to mutations in the CNGB1 gene.

In addition, it develops Phentolamine Ophthalmic Solution for reversal of mydriasis, as well as for the treatment of presbyopia and dim light or night vision disturbances; and APX3330, a small-molecule inhibitor of Ref-1 for the treatment of diabetic retinopathy.

The company was formerly known as Ocuphire Pharma, Inc. Opus Genetics, Inc. was founded in 2018 and is headquartered in Durham, North Carolina.

Opus Genetics, Inc.
CountryUnited States
Founded2018
IndustryPharmaceutical Preparations
Employees18
CEOGeorge Magrath

Contact Details

Address:
8 Davis Drive
Durham, Delaware 27709
United States
Phone984 884 6030
Websiteopusgtx.com

Stock Details

Ticker SymbolR3X1
ExchangeFrankfurt Stock Exchange
Fiscal YearJanuary - December
Reporting CurrencyUSD
SIC Code2834

Key Executives

NamePosition
George MagrathChief Executive Officer
Robert GagnonChief Financial Officer
Joseph SchachleChief Operating Officer
Jenny KobinHead of Investor Relations