CARsgen Therapeutics Holdings Company Description
CARsgen Therapeutics Holdings Limited, an investment holding company, engages in discovering, developing, and commercializing chimeric antigen receptor T (CAR-T) cell therapies for the treatment of hematological malignancies and solid tumors in China and the United States.
Its products include CT053 for the treatment of relapsed/refractory multiple myeloma. The company is also developing autologous CAR-T product candidates, including CT041, which targets Claudin 18.2, is in phase II/III clinical trial for gastric/gastroesophageal junction cancer and pancreatic cancer, as well as in phase I clinical trial for gastric or pancreatic cancer; CT011, which is in phase I clinical trial for patients with targeting Glypican-3 positive to treat hepatocellular carcinoma (HCC); and CT071, that is in Phase I clinical trial which targets G protein-coupled receptor class C group 5 member D for the treatment of R/R MM and relapsed/refractory primary plasma cell leukemia (R/R pPCL).
In addition, it is developing CT0590 and CT059X, which target B-cell maturation antigen and are in phase I clinical trial for the treatment of relapsed/refractory multiple myeloma and R/R PCL, as well as KJ-C2114 that are in the pre-clinical stage for the treatment of solid tumors; and KJ-C2320 for acute myeloid leukemia (AML) that is in phase I.
Further, the company develops KJ-C2219, which is in phase I for the treatment of B-cell malignancies, systemic lupus erythematosus, and systemic sclerosis; and KJ-C2526, which is in the pre-clinical stage to treat AML, other malignancies, and senescence.
It has collaborated with Moderna, Inc. to investigate satricabtagene autoleucel in combination with Moderna’s investigational Claudin18.2 mRNA product.; and East China University of Science and Technology (ECUST) to leverage synergies between academic and industrial resources.
The company was founded in 2014 and is headquartered in Shanghai, China.
Country | Cayman Islands |
Founded | 2014 |
Industry | Biotechnology |
Sector | Healthcare |
Employees | 465 |
CEO | Zonghai Li |
Contact Details
Address: No. 466 Yindu Road Shanghai China | |
Phone | 86 21 6450 1828 |
Website | carsgen.com |
Stock Details
Ticker Symbol | 2171 |
Exchange | Hong Kong Stock Exchange |
Fiscal Year | January - December |
Reporting Currency | CNY |
ISIN Number | KYG1996C1006 |
SIC Code | 2836 |
Key Executives
Name | Position |
---|---|
Dr. Zonghai Li M.D., Ph.D. | Co-Founder, Chief Executive Officer, Chief Scientific Officer and Chairman of the Board |
Dr. Huamao Wang Ph.D. | Co-Founder, Chief Operating Officer and Executive Director |
Dr. Hua Jiang | Executive Director |
Wing Yat Lui | Company Secretary |