Arrowhead Pharmaceuticals, Inc. (LON:0HI3)
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At close: Jul 15, 2025

Arrowhead Pharmaceuticals Company Description

Arrowhead Pharmaceuticals, Inc. develops medicines for the treatment of intractable diseases in the United States.

The company’s product pipeline includes Plozasiran, which has completed Phase 3 clinical trial to treat hypertriglyceridemia, dyslipidemia, and familial chylomicronemia syndrome; Olpasiran that is in Phase 3 clinical trial to reduce the production of apolipoprotein A; and Fazirsiran that is in Phase 3 clinical trial for the treatment of liver disease associated with alpha-1 antitrypsin deficiency.

It also develops Zodasiran that is in Phase 2b clinical trial for the treatment of dyslipidemia and hypertriglyceridemia; GSK-4532990 to treat metabolic-dysfunction associated steatohepatitis (MASH); and Daplusiran/Tomligisiran which is in Phase 2 clinical trial for the treatment of Chronic Hepatitis B.

In addition, the company is developing ARO-PNPLA3, which is in Phase 1 clinical trial to treat patients with MASH; ARO-INHBE to reduce the hepatic expression of the INHBE gene and its secreted gene product; ARO-RAGE to treat inflammatory lung disease; ARO-MUC5AC to treat muco-obstructive pulmonary diseases; and ARO-MMP7 for the treatment of idiopathic pulmonary fibrosis that is in Phase 1/2a clinical trials.

Further, it develops ARO-DUX4 for the treatment of facioscapulohumeral muscular dystrophy; ARO-DM1 to treat patient with Type 1 Myotonic Dystrophy; ARO-C3 to treat complement-mediated renal disease; ARO-CFB for the treatment of complement-mediated kidney disease that is in Phase 1/2a clinical trial; and ARO-ATXN2 for the treatment of Spinocerebellar Ataxia Type 2 that is in Phase 1 clinical trial.

Arrowhead Pharmaceuticals, Inc. has collaboration and license Agreements with Glaxosmithkline Intellectual Property (No.

3) Limited; Horizon Therapeutics Ireland DAC; Takeda Pharmaceutical Company Limited; and with Amgen Inc. The company was founded in 2003 and is headquartered in Pasadena, California.

Arrowhead Pharmaceuticals, Inc.
CountryUnited States
Founded2003
IndustryBiotechnology
SectorHealthcare
Employees609
CEOChristopher Anzalone

Contact Details

Address:
177 East Colorado Boulevard
Pasadena, Delaware 91105
United States
Phone626 304 3400
Websitearrowheadpharma.com

Stock Details

Ticker Symbol0HI3
ExchangeLondon Stock Exchange
Stock TypeCommon Stock
Fiscal YearOctober - September
Reporting CurrencyUSD
ISIN NumberUS04280A1007
SIC Code2836

Key Executives

NamePosition
Dr. Christopher R. Anzalone Ph.D.Chairman, Chief Executive Officer and President
Patrick O'Brien J.D., PharmDChief Operating Officer, General Counsel and Secretary
Dr. James C. Hamilton M.D., MBAChief Medical Officer and Head of Research & Development
Dr. Mark M. Davis Ph.D.Founder and Founder and Director of Insert Therapeutics Inc & Calando
Daniel J. ApelChief Financial Officer
Dr. Vincent Anzalone CFAHead of Investor Relations and Vice President
Howard LovyDirector of Communications
Dr. Bruce D. Given M.D.Chief Medical Scientist
Dr. Mark SeefeldHead of Toxicology and Vice President
Aaron TanHead of Tax