Ionis Pharmaceuticals, Inc. (LON:0JDI)

London flag London · Delayed Price · Currency is GBP · Price in USD
82.09
-1.18 (-1.41%)
Feb 12, 2026, 5:08 PM GMT
Market Cap10.01B +131.2%
Revenue (ttm)719.36M +20.4%
Net Income-190.70M
EPS-1.20
Shares Outn/a
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume1,492
Average Volume620
Open84.51
Previous Close83.27
Day's Range81.67 - 84.97
52-Week Range24.11 - 86.72
Beta0.28
RSI54.57
Earnings DateFeb 18, 2026

About Ionis Pharmaceuticals

Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States. The company offers TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS) and acute pancreatitis; WAINUA for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults; and SPINRAZA for pediatric and adult patients with spinal muscular atrophy (SMA). It also provides QALSODY for the treatment of Amyotrophic Lateral Sclerosis (ALS); TEGSE... [Read more]

Industry Medical - Pharmaceuticals
Sector Healthcare
Founded 1989
Employees 1,069
Stock Exchange London Stock Exchange
Ticker Symbol 0JDI
Full Company Profile

Financial Performance

In 2024, Ionis Pharmaceuticals's revenue was $705.14 million, a decrease of -10.48% compared to the previous year's $787.65 million. Losses were -$453.90 million, 23.9% more than in 2023.

Financial numbers in USD Financial Statements

News

Ionis Pharmaceuticals (IONS) Sees Price Target Raised by Piper Sandler | IONS Stock News

Ionis Pharmaceuticals (IONS) Sees Price Target Raised by Piper Sandler | IONS Stock News

6 days ago - GuruFocus

Insider Sell: Eugene Schneider Sells Shares of Ionis Pharmaceuticals Inc (IONS)

Insider Sell: Eugene Schneider Sells Shares of Ionis Pharmaceuticals Inc (IONS)

9 days ago - GuruFocus

Insider Sell Alert: Shannon Devers Sells Shares of Ionis Pharmaceuticals Inc (IONS)

Insider Sell Alert: Shannon Devers Sells Shares of Ionis Pharmaceuticals Inc (IONS)

19 days ago - GuruFocus

Ionis, Otsuka win EU nod for hereditary angioedema therapy

Ionis Pharmaceuticals (IONS) stock is in focus as the EU approves the company's hereditary angioedema drug marketed with Otsuka Pharmaceutical (OTSKY). Read more here.

22 days ago - Seeking Alpha

EU Approves DAWNZERA For Hereditary Angioedema, Says Ionis And Otsuka

(RTTNews) - Ionis Pharmaceuticals, Inc. (IONS) and Otsuka Pharmaceutical Co., Ltd. on Wednesday said the European Commission has approved Dawnzera to prevent repeated attacks of hereditary angioedema ...

22 days ago - Nasdaq

Ionis Pharmaceuticals (IONS) Gains EU Approval for Dawnzera

Ionis Pharmaceuticals (IONS) Gains EU Approval for Dawnzera

22 days ago - GuruFocus

DAWNZERA™ (donidalorsen) approved in the European Union for hereditary angioedema (HAE)

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) and Otsuka Pharmaceutical Co., Ltd. (Otsuka) today announced that the European Commission (EC) has approved DAWNZERA™ (don...

22 days ago - Business Wire

Ionis: Expected 2026 Launch Of Olezarsen In SHTG To Spur Leap In Revenue Growth

Ionis Pharmaceuticals (IONS) has appreciated ~25% since my last upgrade, reflecting strong momentum. This article spotlights Olezarsen, Ionis's wholly owned molecule, as a key driver of future upside....

23 days ago - Seeking Alpha

Ionis Pharmaceuticals Inc at JPMorgan Healthcare Conference Transcript

Ionis Pharmaceuticals Inc at JPMorgan Healthcare Conference Transcript

4 weeks ago - GuruFocus

Ionis Pharmaceuticals, Inc. (IONS) Presents at 44th Annual J.P. Morgan Healthcare Conference Transcript

Ionis Pharmaceuticals, Inc. (IONS) 44th Annual J.P.

4 weeks ago - Seeking Alpha

Ionis well-positioned for continued momentum and substantial value creation in 2026 with two new independent launches and several pivotal data readouts

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced highlights from the Company's 2025 achievements and provided additional updates on key milestones expected...

4 weeks ago - Business Wire

Insider Sell Alert: Shannon Devers Sells 44,199 Shares of Ionis Pharmaceuticals Inc (IONS)

Insider Sell Alert: Shannon Devers Sells 44,199 Shares of Ionis Pharmaceuticals Inc (IONS)

4 weeks ago - GuruFocus

GSK/Ionis Partnered Investigational Drug Shows Strong Results In Large Hepatitis B Studies

Ionis Pharmaceuticals Inc . (NASDAQ: IONS) partner GSK Plc (NYSE: GSK) on Wednesday shared data from two pivotal Phase 3 studies, B-Well 1 and B-Well 2, of bepirovirsen, an investigational antisense...

5 weeks ago - Benzinga

GSK/Ionis Partnered Investigational Drug Shows Strong Results In Large Hepatitis B Studies

Ionis Pharmaceuticals Inc. (NASDAQ: IONS) partner GSK Plc (NYSE: GSK) on Wednesday shared data from two pivotal Phase 3 studies, B-Well 1 and B-Well 2, of bepirovirsen, an investigational antisense ol...

5 weeks ago - Benzinga

Ionis partner GSK announces positive topline results from B-Well 1 and B-Well 2 Phase 3 studies for bepirovirsen, a potential first-in-class medicine for chronic hepatitis B

– Primary endpoint met in both trials – – Bepirovirsen demonstrated a statistically significant and clinically meaningful functional cure rate – – Chronic hepatitis B (CHB) accounts for ~56% of liver ...

5 weeks ago - Benzinga

Ionis partner GSK announces positive topline results from B-Well 1 and B-Well 2 Phase 3 studies for bepirovirsen, a potential first-in-class medicine for chronic hepatitis B

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) partner GSK today announced positive results from two pivotal Phase 3 studies, B-Well 1 and B-Well 2, evaluating the safet...

5 weeks ago - Business Wire

Ionis to present at 44th Annual J.P. Morgan Healthcare Conference

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that Brett P. Monia, Ph.D., chief executive officer, will present a company overview at the 44th Annual J....

5 weeks ago - Business Wire

Wells Fargo Raises Price Target for Ionis Pharmaceuticals (IONS) to $100 | IONS Stock News

Wells Fargo Raises Price Target for Ionis Pharmaceuticals (IONS) to $100 | IONS Stock News

5 weeks ago - GuruFocus

RBC Capital Raises Price Target for Ionis Pharmaceuticals (IONS) to $95 | IONS Stock News

RBC Capital Raises Price Target for Ionis Pharmaceuticals (IONS) to $95 | IONS Stock News

2 months ago - GuruFocus

Ionis Pharmaceuticals (IONS): Leerink Partners Raises Price Target | IONS Stock News

Ionis Pharmaceuticals (IONS): Leerink Partners Raises Price Target | IONS Stock News

2 months ago - GuruFocus

Ionis Pharmaceuticals (IONS) Price Target Raised by B of A Securities | IONS Stock News

Ionis Pharmaceuticals (IONS) Price Target Raised by B of A Securities | IONS Stock News

2 months ago - GuruFocus

Ionis Pharmaceuticals (IONS) Gains FDA Breakthrough Therapy Designation

Ionis Pharmaceuticals (IONS) Gains FDA Breakthrough Therapy Designation

2 months ago - GuruFocus

Ionis Pharma: FDA Grants Breakthrough Therapy Designation To Zilganersen

(RTTNews) - Ionis Pharmaceuticals (IONS) announced that the FDA has granted Breakthrough Therapy designation to zilganersen for the treatment of Alexander disease. The FDA's designation is supported b...

2 months ago - Nasdaq

FDA Grants Breakthrough Therapy Status to Ionis Pharmaceuticals' Zilganersen (IONS)

FDA Grants Breakthrough Therapy Status to Ionis Pharmaceuticals' Zilganersen (IONS)

2 months ago - GuruFocus