Ionis Pharmaceuticals, Inc. (LON:0JDI)

London flag London · Delayed Price · Currency is GBP · Price in USD
61.11
-2.61 (-4.09%)
At close: Sep 15, 2025
-4.09%
Market Cap7.16B
Revenue (ttm)689.06M
Net Income (ttm)-195.77M
Shares Outn/a
EPS (ttm)-1.26
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume2,819
Average Volume2,870
Open62.94
Previous Close63.72
Day's Range61.03 - 63.21
52-Week Range24.11 - 65.63
Betan/a
RSI69.93
Earnings DateNov 5, 2025

About Ionis Pharmaceuticals

Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States. The company offers TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS) and acute pancreatitis; WAINUA for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults; and SPINRAZA for pediatric and adult patients with spinal muscular atrophy (SMA). It also provides QALSODY for the treatment of Amyotrophic Lateral Sclerosis (ALS); TEGSE... [Read more]

Industry Medical - Pharmaceuticals
Sector Healthcare
Founded 1989
Employees 1,069
Stock Exchange London Stock Exchange
Ticker Symbol 0JDI
Full Company Profile

Financial Performance

In 2024, Ionis Pharmaceuticals's revenue was $705.14 million, a decrease of -10.48% compared to the previous year's $787.65 million. Losses were -$453.90 million, 23.9% more than in 2023.

Financial numbers in USD Financial Statements

News

Ionis expands Surf Away+ event, marking 10 years of creating unique adaptive experiences for people with neurological diseases

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today celebrated 10 years of Surf Away+, an inclusive adaptive event for rare neurological disease communities. Originally...

4 days ago - Business Wire

Insider Sell: Patrick O'neil Sells 21,000 Shares of Ionis Pharmaceuticals Inc (IONS)

Insider Sell: Patrick O'neil Sells 21,000 Shares of Ionis Pharmaceuticals Inc (IONS)

4 days ago - GuruFocus

Ionis: Recent Approvals, Upcoming Catalysts To Spur Strong Upside (Rating Upgrade)

After years of futility, Ionis' recent regulatory and clinical successes have spurred optimistic market attention. I review Q2/2025 earnings documents together with 09/04/2025 CEO Monia interview and ...

5 days ago - Seeking Alpha

Ionis Pharmaceuticals To Expedite Development Of Rare Neurological Disease Candidate With FDA Breakthrough Status

On Tuesday, the U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy designation to Ionis Pharmaceuticals Inc.’s (NASDAQ: IONS) ION582 for Angelman syndrome (AS), a rare neurological ...

6 days ago - Benzinga

Ionis Pharmaceuticals To Expedite Development Of Rare Neurological Disease Candidate With FDA Breakthrough Status

On Tuesday, the U.S. Food and Drug Administration (FDA) granted Breakthrough Therapy designation to Ionis Pharmaceuticals Inc.'s IONS ION582 for Angelman syndrome (AS), a rare neurological disorder.

6 days ago - Benzinga

Ionis gets FDA breakthrough therapy status for angelman syndrome drug

Ionis Pharmaceuticals gains FDA breakthrough status for ION582, showing promise for Angelman syndrome. Read more here.

6 days ago - Seeking Alpha

Ionis Pharmaceuticals Inc (IONS) Receives FDA Breakthrough Therapy Designation for ION582 | ...

Ionis Pharmaceuticals Inc (IONS) Receives FDA Breakthrough Therapy Designation for ION582 | IONS stock news

6 days ago - GuruFocus

FDA Grants Breakthrough Therapy Status to Ionis Pharmaceuticals' ION582

FDA Grants Breakthrough Therapy Status to Ionis Pharmaceuticals' ION582

6 days ago - GuruFocus

Ionis receives U.S. FDA Breakthrough Therapy designation for ION582 in Angelman syndrome

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to ION582 fo...

7 days ago - Business Wire

Ionis Pharmaceuticals Announces Ionis Innovation Day 2025 | IONS stock news

Ionis Pharmaceuticals Announces Ionis Innovation Day 2025 | IONS stock news

7 days ago - GuruFocus

Ionis to host investors and analysts for Innovation Day 2025

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that it will host Ionis Innovation Day on Tuesday, October 7, 2025, in New York. The agenda will feature p...

7 days ago - Business Wire

Insider Sell: Brett Monia Sells 203,814 Shares of Ionis Pharmaceuticals Inc (IONS)

Insider Sell: Brett Monia Sells 203,814 Shares of Ionis Pharmaceuticals Inc (IONS)

11 days ago - GuruFocus

RBC Capital Raises Ionis Pharmaceuticals (IONS) Price Target to $80 | IONS Stock News

RBC Capital Raises Ionis Pharmaceuticals (IONS) Price Target to $80 | IONS Stock News

11 days ago - GuruFocus

Ionis Pharmaceuticals (IONS): Citigroup Raises Price Target to $84 | IONS Stock News

Ionis Pharmaceuticals (IONS): Citigroup Raises Price Target to $84 | IONS Stock News

12 days ago - GuruFocus

Goldman Sachs Maintains "Sell" on Ionis Pharmaceuticals (IONS), Raises Target Price | ...

Goldman Sachs Maintains "Sell" on Ionis Pharmaceuticals (IONS), Raises Target Price | IONS Stock News

12 days ago - GuruFocus

Ionis Pharmaceuticals (IONS) Upgraded to Outperform by BMO Capital | IONS Stock News

Ionis Pharmaceuticals (IONS) Upgraded to Outperform by BMO Capital | IONS Stock News

12 days ago - GuruFocus

Ionis Pharmaceuticals (IONS): Barclays Raises Price Target to $78 | IONS Stock News

Ionis Pharmaceuticals (IONS): Barclays Raises Price Target to $78 | IONS Stock News

12 days ago - GuruFocus

Is The 35% Rally In IONS Stock Just The Beginning?

Ionis Pharmaceuticals' stock jumped 35% on September 2, 2025, after positive late-stage clinical trial results for olezarsen, a therapy for severe hypertriglyceridemia (sHTG). Investor enthusiasm is a...

12 days ago - Forbes

Ionis Pharmaceuticals Inc (IONS) Announces Participation in Upcoming Investor Conferences | ...

Ionis Pharmaceuticals Inc (IONS) Announces Participation in Upcoming Investor Conferences | IONS stock news

13 days ago - GuruFocus

Ionis to present at upcoming investor conferences

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will participate in fireside chats at the following investor conferences: 2025 Wells Fargo...

13 days ago - Business Wire

Jefferies Raises Ionis Pharmaceuticals (IONS) Price Target to $96 | IONS Stock News

Jefferies Raises Ionis Pharmaceuticals (IONS) Price Target to $96 | IONS Stock News

13 days ago - GuruFocus

Needham Analyst Joseph Stringer Raises Ionis Pharmaceuticals (IONS) Price Target | IONS Stock News

Needham Analyst Joseph Stringer Raises Ionis Pharmaceuticals (IONS) Price Target | IONS Stock News

13 days ago - GuruFocus