Ionis Pharmaceuticals, Inc. (LON:0JDI)

London flag London · Delayed Price · Currency is GBP · Price in USD
77.60
-0.92 (-1.17%)
Dec 19, 2025, 6:38 AM BST
107.99%
Market Cap9.32B
Revenue (ttm)719.36M
Net Income (ttm)-190.70M
Shares Outn/a
EPS (ttm)-1.20
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume40
Average Volume288
Open77.60
Previous Close78.52
Day's Range77.60 - 77.60
52-Week Range24.11 - 83.00
Betan/a
RSI49.00
Earnings DateFeb 18, 2026

About Ionis Pharmaceuticals

Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States. The company offers TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS) and acute pancreatitis; WAINUA for the treatment of the polyneuropathy of hereditary transthyretin-medicated amyloidosis (ATTRv-PN) in adults; and SPINRAZA for pediatric and adult patients with spinal muscular atrophy (SMA). It also provides QALSODY for the treatment of Amyotrophic Lateral Sclerosis (ALS); TEGSE... [Read more]

Industry Medical - Pharmaceuticals
Sector Healthcare
Founded 1989
Employees 1,069
Stock Exchange London Stock Exchange
Ticker Symbol 0JDI
Full Company Profile

Financial Performance

In 2024, Ionis Pharmaceuticals's revenue was $705.14 million, a decrease of -10.48% compared to the previous year's $787.65 million. Losses were -$453.90 million, 23.9% more than in 2023.

Financial numbers in USD Financial Statements

News

Ionis Pharmaceuticals (IONS): Leerink Partners Raises Price Target | IONS Stock News

Ionis Pharmaceuticals (IONS): Leerink Partners Raises Price Target | IONS Stock News

3 days ago - GuruFocus

Ionis Pharmaceuticals (IONS) Price Target Raised by B of A Securities | IONS Stock News

Ionis Pharmaceuticals (IONS) Price Target Raised by B of A Securities | IONS Stock News

9 days ago - GuruFocus

Ionis Pharmaceuticals (IONS) Gains FDA Breakthrough Therapy Designation

Ionis Pharmaceuticals (IONS) Gains FDA Breakthrough Therapy Designation

16 days ago - GuruFocus

Ionis Pharma: FDA Grants Breakthrough Therapy Designation To Zilganersen

(RTTNews) - Ionis Pharmaceuticals (IONS) announced that the FDA has granted Breakthrough Therapy designation to zilganersen for the treatment of Alexander disease. The FDA's designation is supported b...

16 days ago - Nasdaq

FDA Grants Breakthrough Therapy Status to Ionis Pharmaceuticals' Zilganersen (IONS)

FDA Grants Breakthrough Therapy Status to Ionis Pharmaceuticals' Zilganersen (IONS)

16 days ago - GuruFocus

Ionis receives U.S. FDA Breakthrough Therapy designation for zilganersen for Alexander disease (AxD)

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to zilganers...

16 days ago - Business Wire

Ionis Wins FDA Breakthrough Therapy Designation For Olezarsen In Severe Hypertriglyceridemia

(RTTNews) - Ionis Pharmaceutical Inc. (IONS) today announced that the U.S. FDA has granted Breakthrough Therapy designation to olezarsen as an adjunct to diet to reduce triglyceride (TG) levels in adu...

17 days ago - Nasdaq

Ionis receives U.S. FDA Breakthrough Therapy designation for olezarsen for severe hypertriglyceridemia (sHTG)

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to olezarsen...

17 days ago - Business Wire

Insider Sell: Shannon Devers Sells 16,777 Shares of Ionis Pharmaceuticals Inc (IONS)

Insider Sell: Shannon Devers Sells 16,777 Shares of Ionis Pharmaceuticals Inc (IONS)

20 days ago - GuruFocus

Insider Sell: Joan Herman Sells 44,000 Shares of Ionis Pharmaceuticals Inc (IONS)

Insider Sell: Joan Herman Sells 44,000 Shares of Ionis Pharmaceuticals Inc (IONS)

4 weeks ago - GuruFocus

Ionis Pharmaceuticals, Inc. (IONS) Presents at Jefferies London Healthcare Conference 2025 Transcript

Ionis Pharmaceuticals, Inc. (IONS) Jefferies London Healthcare Conference 2025 November 18, 2025 8:30 AM ESTCompany ParticipantsBrett Monia - Founder, CEO...

4 weeks ago - Seeking Alpha

Ionis' DAWNZERA Gains CHMP Backing For Approval In Europe For Hereditary Angioedema

(RTTNews) - Ionis Pharmaceuticals Inc. (IONS) announced that the Committee for Medicinal Products for Human Use, or CHMP, of the European Medicines Agency has adopted a positive opinion recommending a...

4 weeks ago - Nasdaq

Ionis Pharmaceuticals (IONS) in Tweedy Browne Q3 2025

Ionis Pharmaceuticals (IONS) in Tweedy Browne Q3 2025

4 weeks ago - GuruFocus

Biogen Completes Acquisition of Alcyone Therapeutics

CAMBRIDGE, Mass., Nov. 14, 2025 (GLOBE NEWSWIRE) -- Biogen Inc. (Nasdaq: BIIB) has completed the acquisition of Alcyone Therapeutics, a clinical-stage biotechnology company known for its innovative CN...

4 weeks ago - GlobeNewsWire

Ionis Pharmaceuticals (IONS) Advances with European Review for Dawnzera

Ionis Pharmaceuticals (IONS) Advances with European Review for Dawnzera

4 weeks ago - GuruFocus

DAWNZERA™ (donidalorsen) receives positive opinion from CHMP, recommended for approval in EU for hereditary angioedema (HAE)

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) and Otsuka Pharmaceutical Co., Ltd. (Otsuka) today announced that the Committee for Medicinal Products for Human Use (CHMP...

4 weeks ago - Business Wire

Ionis Pharmaceuticals, Inc. (IONS) Presents at Stifel 2025 Healthcare Conference Transcript

Ionis Pharmaceuticals, Inc. (IONS) Stifel 2025 Healthcare Conference November 13, 2025 8:00 AM ESTCompany ParticipantsKyle Jenne - Executive VP & Chief...

5 weeks ago - Seeking Alpha

Ionis Prices Convertible Notes Offering to Refinance 2026 Convertible Notes

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) announced today the pricing of $700.0 million aggregate principal amount of 0.00% Convertible Senior Notes due 2030 (the “...

5 weeks ago - Business Wire

Ionis to present at upcoming investor conferences

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced that management will participate in fireside chats at the following investor conferences: Stifel 2025 Heal...

5 weeks ago - Business Wire

Ionis Pharmaceuticals (IONS) Announces $700 Million Convertible Notes Offering

Ionis Pharmaceuticals (IONS) Announces $700 Million Convertible Notes Offering

5 weeks ago - GuruFocus

Ionis Pharmaceuticals (IONS) Plans $700M Convertible Notes Offering

Ionis Pharmaceuticals (IONS) Plans $700M Convertible Notes Offering

5 weeks ago - GuruFocus

Ionis Announces Proposed Convertible Offering to Refinance 2026 Convertible Notes

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) announced today that it intends to offer, subject to market conditions and other factors, $700.0 million aggregate princip...

5 weeks ago - Business Wire

Ionis Pharmaceuticals, Inc. (IONS) Discusses Detailed Phase III Results for Olezarsen in Severe Hypertriglyceridemia - Slideshow

2025-11-10. The following slide deck was published by Ionis Pharmaceuticals, Inc.

5 weeks ago - Seeking Alpha