Ionis Pharmaceuticals, Inc. (LON: 0JDI)
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Jan 23, 2025, 2:42 PM BST

Ionis Pharmaceuticals Company Description

Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States.

The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an antisense injection for the treatment of polyneuropathy caused by hereditary transthyretin amyloidosis in adults; and WAYLIVRA, an antisense medicine for treatment for familial chylomicronemia syndrome (FCS) and familial partial lipodystrophy.

It also develops medicines for various indications that are in phase 3 study, including Eplontersen as a monthly self-administered subcutaneous injection to treat all types of ATTR; Olezarsen for patients with FCS and severe hypertriglyceridemia (SHTG); Donidalorsen for patients with hereditary angioedema; ION363 for patients with amyotrophic lateral sclerosis; Tofersen to inhibit the production of superoxide dismutase 1; Pelacarsen for patients with established cardiovascular disease and elevated lipoprotein(a); and Bepirovirsen to inhibit the production of viral proteins associated with hepatitis B virus.

In addition, the company develops IONIS-FB-LRx to inhibit the production of complement factor B and the alternative complement pathway; and ION224 to reduce the production of diacylglycerol acyltransferase 2.

It has a strategic collaboration with Biogen for the treatment of neurological disorders; and collaboration and license agreement with Metagenomi, Inc, AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis, Roche, Swedish Orphan Biovitrum AB, and PTC Therapeutics.

The company was incorporated in 1989 and is based in Carlsbad, California.

Ionis Pharmaceuticals, Inc.
Country United States
Founded 1989
Industry Medical - Pharmaceuticals
Sector Healthcare
Employees 927
CEO Brett Monia

Contact Details

Address:
2855 Gazelle Court
Carlsbad, Delaware 92010
United States
Phone 760 931 9200
Website ionispharma.com

Stock Details

Ticker Symbol 0JDI
Exchange London Stock Exchange
Stock Type Common Stock
Fiscal Year January - December
Reporting Currency USD
ISIN Number US4622221004
SIC Code 2836

Key Executives

Name Position
Brett Monia Chief Executive Officer
Elizabeth Hougen Chief Financial Officer
D. Walke Head of Investor Relations