Madrigal Pharmaceuticals, Inc. (LON:0JXI)

London flag London · Delayed Price · Currency is GBP · Price in USD
496.40
+18.94 (3.97%)
At close: Jun 4, 2026
Market Cap8.39B +83.3%
Revenue (ttm)857.64M +256.8%
Net Income-234.34M
EPS-10.34
Shares Out n/a
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume7
Open495.27
Previous Close477.46
Day's Range486.00 - 497.42
52-Week Range275.13 - 610.61
Beta-1.05
Analystsn/a
Price Targetn/a
Earnings DateAug 4, 2026

About Madrigal Pharmaceuticals

Madrigal Pharmaceuticals, Inc., a biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States. It offers Rezdiffra, a liver-directed thyroid hormone receptor beta agonist for treating MASH. The company was founded in 2016 and is headquartered in West Conshohocken, Pennsylvania. [Read more]

Industry Pharmaceutical Preparations
Founded 2016
Employees 915
Stock Exchange London Stock Exchange
Ticker Symbol 0JXI

Financial Performance

In 2025, Madrigal Pharmaceuticals's revenue was $958.40 million, an increase of 432.05% compared to the previous year's $180.13 million. Losses were -$288.28 million, -38.12% less than in 2024.

Financial numbers in USD Financial Statements

News

Madrigal Pharmaceuticals announces new analyses of Rezdiffra data

Madrigal Pharmaceuticals (MDGL) announced new analyses of Phase 3 data and real-world evidence demonstrating Rezdiffra reduced markers of cardiovascular and liver-related risk in patients with MASH. T...

10 days ago - TheFly

Madrigal Pharmaceuticals price target raised to $709 from $640 at Truist

Truist raised the firm’s price target on Madrigal Pharmaceuticals (MDGL) to $709 from $640 and keeps a Buy rating on the shares. The firm’s survey work reinforces its belief in…

24 days ago - TheFly

Madrigal Pharmaceuticals price target lowered to $578 from $587 at Canaccord

Canaccord lowered the firm’s price target on Madrigal Pharmaceuticals (MDGL) to $578 from $587 and keeps a Buy rating on the shares. The firm updated its model following Q1 results…

4 weeks ago - TheFly

Madrigal Pharmaceuticals price target lowered to $649 from $652 at Evercore ISI

Evercore ISI lowered the firm’s price target on Madrigal Pharmaceuticals (MDGL) to $649 from $652 and keeps an Outperform rating on the shares.

4 weeks ago - TheFly

Madrigal Pharmaceuticals reports Q1 EPS ($3.25), consensus ($4.14)

Reports Q1 revenue $311.34M, consensus $300.92M. Bill Sibold, Chief Executive Officer of Madrigal, stated: “2026 is off to a terrific start. Rezdiffra has achieved blockbuster status on a trailing-12-...

4 weeks ago - TheFly

Madrigal Pharmaceuticals price target raised to $680 from $533 at Clear Street

Clear Street raised the firm’s price target on Madrigal Pharmaceuticals (MDGL) to $680 from $533 and keeps a Buy rating on the shares post the Q1 report. The firm says…

4 weeks ago - TheFly

Madrigal Pharmaceuticals Earnings Call Transcript: Q1 2026

Rezdiffra posted $311M in Q1 2026 net sales, up 127% year-over-year, with over 42,250 active patients and strong market expansion. The company is investing in a broad pipeline and expects robust growth, though profitability is not anticipated in 2026.

4 weeks ago - Transcripts

Madrigal Pharmaceuticals Earnings release: Q1 2026

Madrigal Pharmaceuticals released its Q1 2026 earnings on May 6, 2026, summarizing the period's financial results.

4 weeks ago - Filings

Madrigal Pharmaceuticals Slides: Q1 2026

Madrigal Pharmaceuticals has posted slides in relation to its Q1 2026 quarterly earnings report, which was published on May 6, 2026.

4 weeks ago - Filings

Madrigal Pharmaceuticals Quarterly report: Q1 2026

Madrigal Pharmaceuticals has published its Q1 2026 quarterly earnings report on May 6, 2026.

4 weeks ago - Filings

Arrowhead announces exclusive worldwide license agreement with Madrigal Pharma

Arrowhead Pharmaceuticals (ARWR) announced an exclusive worldwide license agreement with Madrigal Pharmaceuticals (MDGL) for ARO-PNPLA3, Arrowhead’s clinical stage RNA interference therapeutic designe...

4 weeks ago - TheFly

Madrigal Pharmaceuticals Proxy statement: Proxy filing

Madrigal Pharmaceuticals filed a proxy statement on April 28, 2026, providing details for shareholder voting and corporate governance matters.

5 weeks ago - Filings

Madrigal Pharmaceuticals Proxy statement: Proxy filing

Madrigal Pharmaceuticals filed a proxy statement on April 28, 2026, providing details for shareholder voting and corporate governance matters.

5 weeks ago - Filings

Madrigal Pharmaceuticals off highs, remains up 13% in afternoon trading

14:57 EDT Madrigal Pharmaceuticals (MDGL) off highs, remains up 13% in afternoon trading

2 months ago - TheFly

Madrigal Pharmaceuticals Transcript: TD Cowen 46th Annual Health Care Conference

Rezdiffra is driving strong revenue growth, with 2025 sales projected near $1 billion and a robust pipeline expansion. Market penetration remains low, offering significant upside, while international growth and new combination therapies are set to accelerate from 2027 onward.

3 months ago - Transcripts

Madrigal Pharmaceuticals price target lowered to $529 from $570 at BofA

BofA lowered the firm’s price target on Madrigal Pharmaceuticals (MDGL) to $529 from $570 and keeps a Neutral rating on the shares. Following quarterly results and the associated call, the…

3 months ago - TheFly

Madrigal Pharmaceuticals Earnings Call Transcript: Q4 2025

Rezdiffra achieved nearly $1B in first-year net sales, driving robust growth in a rapidly expanding US MASH market. The company expects continued strong performance in 2026, supported by a deep pipeline, broad payer access, and a strong cash position.

3 months ago - Transcripts

Madrigal Pharmaceuticals Annual report: Q4 2025

Madrigal Pharmaceuticals has published its Q4 2025 annual report on February 19, 2026.

3 months ago - Filings

Madrigal Pharmaceuticals Earnings release: Q4 2025

Madrigal Pharmaceuticals released its Q4 2025 earnings on February 19, 2026, summarizing the period's financial results.

3 months ago - Filings

Madrigal Pharmaceuticals Slides: Q4 2025

Madrigal Pharmaceuticals has posted slides in relation to its Q4 2025 quarterly earnings report, which was published on February 19, 2026.

3 months ago - Filings

Madrigal Pharmaceuticals reports Q4 EPS ($2.57), consensus (88c)

Reports Q4 revenue $321.083M, consensus $312.74M. Bill Sibold, Chief Executive Officer of Madrigal, stated: “2025 marked a defining year for Madrigal. We solidified our position as the undisputed lead...

3 months ago - TheFly

Madrigal Pharmaceuticals announces exclusive license pact with Suzho Ribo

Madrigal Pharmaceuticals (MDGL) announced an exclusive global license agreement with Suzhou Ribo Life Science and its subsidiary Ribocure Pharmaceuticals for six preclinical small interfering RNA prog...

4 months ago - TheFly

Madrigal Pharmaceuticals price target lowered to $570 from $595 at BofA

BofA lowered the firm’s price target on Madrigal Pharmaceuticals (MDGL) to $570 from $595 and keeps a Neutral rating on the shares. Given the level of pre-announcements, upcoming Q4 earnings…

4 months ago - TheFly

Madrigal Pharmaceuticals initiated with an Overweight at Barclays

Barclays initiated coverage of Madrigal Pharmaceuticals (MDGL) with an Overweight rating and $964 price target Barclays initiated coverage of 12 biotech stocks and assumed coverage of 11 with a positi...

4 months ago - TheFly

Madrigal Pharmaceuticals price target raised to $745 from $527 at Citizens

Citizens raised the firm’s price target on Madrigal Pharmaceuticals (MDGL) to $745 from $527 and keeps an Outperform rating on the shares. Rezdiffra’s extended intellectual property coverage and multi...

4 months ago - TheFly