Vertex Pharmaceuticals Incorporated (LON: 0QZU)
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400.87
+10.23 (2.62%)
Dec 23, 2024, 6:44 PM BST

Vertex Pharmaceuticals Company Description

Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF).

It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age or older; SYMDEKO/SYMKEVI for people with CF for 6 years of age or older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 year or older who have CF with ivacaftor.

The company’s pipeline includes VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1 clinical trial; VX-548, a non-opioid medicine for the treatment of acute and neuropathic pain which is in Phase 3 clinical trial; Exa-cel, for the treatment of sickle cell disease and transfusion-dependent beta thalassemia which is in Phase 2/3 clinical trial.

In addition, it provides inaxaplin for the treatment of APOL1-mediated focal segmental glomerulosclerosis and co-morbidities, such as hypertension which is in single Phase 2/3; VX- 880 and VX-264, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-970, which is in Phase 2 clinical trial for the treatment of cancer; and VX-803 and VX-984 for treatment of cancer in Phase 1 clinical trial.

Further, it sells the products to specialty pharmacy and specialty distributors in the United States, as well as retail pharmacies, hospitals, and clinics.

Additionally, the company has collaborations with CRISPR Therapeutics AG.; Moderna, Inc.; Entrada Therapeutics, Inc.; Arbor Biotechnologies, Inc.; Mammoth Biosciences, Inc.; and Verve Therapeutics., as well as collaborations with Tevard Biosciences to develop novel tRNA-based therapies for duchenne muscular dystrophy.

Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.

Vertex Pharmaceuticals Incorporated
Country United States
Founded 1989
Industry Medical - Pharmaceuticals
Sector Healthcare
Employees 5,400
CEO Reshma Kewalramani

Contact Details

Address:
50 Northern Avenue
Boston, Massachusetts 02210
United States
Phone 617 341 6100
Website vrtx.com

Stock Details

Ticker Symbol 0QZU
Exchange London Stock Exchange
Fiscal Year January - December
Reporting Currency USD
ISIN Number US92532F1003
SIC Code 2834

Key Executives

Name Position
Dr. Reshma Kewalramani FASN, M.D. Chief Executive Officer, President and Director
Dr. Jeffrey Marc Leiden M.D., Ph.D. Executive Chairman
Charles F. Wagner Jr. Executive Vice President and Chief Financial Officer
Stuart A. Arbuckle B.Sc. Executive Vice President and Chief Operating Officer
Dr. David M. Altshuler M.D., Ph.D. Executive Vice President and Chief Scientific Officer
Kristen C. Ambrose CPA Senior Vice President and Chief Accounting Officer
Mike Tirozzi SVice President and Chief Information and Data Officer
Susie Lisa C.F.A. Senior Vice President of Investor Relations
Jonathan Biller J.D. Executive Vice President and Chief Legal Officer
Nina Devlin Senior Vice President and Chief Communications Officer