Prothena Corporation Ratios and Metrics

Market cap in millions GBP. Fiscal year is January - December.

Millions GBP. Fiscal year is Jan - Dec.

Fiscal Year	Current	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020	2015 - 2019
Period Ending	Nov '25 Nov 3, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021	Dec '20 Dec 31, 2020	2015 - 2019
Market Capitalization	423	595	1,531	2,582	1,700	351	Upgrade
Market Cap Growth	-39.97%	-61.12%	-40.69%	51.87%	384.06%	-26.36%	Upgrade
Enterprise Value	146	190	1,013	2,177	1,267	135	Upgrade
Last Close Price	7.83	10.50	28.72	49.63	31.29	8.72	Upgrade
PE Ratio	-	-	-	-	34.37	-	Upgrade
PS Ratio	56.09	5.51	21.34	57.70	11.48	562.08	Upgrade
PB Ratio	1.79	1.53	3.47	5.00	4.94	2.61	Upgrade
P/TBV Ratio	1.79	1.53	3.47	5.00	4.94	2.61	Upgrade
P/FCF Ratio	-	-	-	-	25.01	-	Upgrade
P/OCF Ratio	-	-	-	-	24.86	-	Upgrade
EV/Sales Ratio	18.44	1.76	14.12	48.66	8.55	215.82	Upgrade
EV/EBITDA Ratio	-	-	-	-	23.47	-	Upgrade
EV/EBIT Ratio	-	-	-	-	23.83	-	Upgrade
EV/FCF Ratio	-1.04	-	-	-	18.64	-	Upgrade
Debt / Equity Ratio	0.03	0.02	0.02	0.01	0.03	0.10	Upgrade
Debt / EBITDA Ratio	-	-	-	-	0.16	-	Upgrade
Debt / FCF Ratio	-	-	-	-	0.13	-	Upgrade
Asset Turnover	0.02	0.22	0.13	0.08	0.43	0.00	Upgrade
Quick Ratio	5.48	9.72	10.97	14.17	17.31	11.43	Upgrade
Current Ratio	5.69	10.01	11.24	14.34	17.48	11.58	Upgrade
Return on Equity (ROE)	-66.85%	-23.34%	-24.85%	-21.50%	20.61%	-48.65%	Upgrade
Return on Assets (ROA)	-29.79%	-15.54%	-16.42%	-12.03%	9.55%	-18.73%	Upgrade
Return on Capital (ROIC)	-33.53%	-18.04%	-19.87%	-14.86%	13.23%	-28.31%	Upgrade
Return on Capital Employed (ROCE)	-	-	-	-	12.50%	-	Upgrade
Earnings Yield	-52.23%	-16.41%	-7.54%	-3.76%	2.91%	-23.18%	Upgrade
FCF Yield	-33.25%	-20.17%	-7.01%	-3.51%	4.00%	-16.80%	Upgrade
Buyback Yield / Dilution	-0.25%	-1.04%	-12.34%	2.26%	-21.42%	-0.08%	Upgrade

Updated Jun 30, 2025. Source: S&P Global Market Intelligence. Standard template. Financial Sources.