Prothena Corporation plc (LON:0Y3M)

Prothena Corporation Ratios and Metrics

Market cap in millions GBP. Fiscal year is January - December.

Fiscal Year	Current	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020
Period Ending	Dec 16, 2025	Dec 31, 2024	Dec 31, 2023	Dec 31, 2022	Dec 31, 2021	Dec 31, 2020
Market Capitalization	377	595	1,531	2,582	1,700	351
Market Cap Growth	-35.63%	-61.12%	-40.69%	51.87%	384.06%	-26.36%
Enterprise Value	137	190	1,013	2,177	1,267	135
Last Close Price	7.09	10.50	28.72	49.63	31.29	8.72
PE Ratio	-	-	-	-	34.37	-
PS Ratio	42.99	5.51	21.34	57.70	11.48	562.08
PB Ratio	1.72	1.53	3.47	5.00	4.94	2.61
P/TBV Ratio	1.72	1.53	3.47	5.00	4.94	2.61
P/FCF Ratio	-	-	-	-	25.01	-
P/OCF Ratio	-	-	-	-	24.86	-
EV/Sales Ratio	15.54	1.76	14.12	48.66	8.55	215.82
EV/EBITDA Ratio	-	-	-	-	23.47	-
EV/EBIT Ratio	-	-	-	-	23.83	-
EV/FCF Ratio	-0.98	-	-	-	18.64	-
Debt / Equity Ratio	0.03	0.02	0.02	0.01	0.03	0.10
Debt / EBITDA Ratio	-	-	-	-	0.16	-
Debt / FCF Ratio	-	-	-	-	0.13	-
Asset Turnover	0.03	0.22	0.13	0.08	0.43	0.00
Quick Ratio	6.43	9.72	10.97	14.17	17.31	11.43
Current Ratio	6.61	10.01	11.24	14.34	17.48	11.58
Return on Equity (ROE)	-67.63%	-23.34%	-24.85%	-21.50%	20.61%	-48.65%
Return on Assets (ROA)	-29.31%	-15.54%	-16.42%	-12.03%	9.55%	-18.73%
Return on Capital (ROIC)	-32.69%	-18.04%	-19.87%	-14.86%	13.23%	-28.31%
Return on Capital Employed (ROCE)	-73.80%	-31.00%	-29.90%	-18.60%	12.50%	-36.70%
Earnings Yield	-55.35%	-16.41%	-7.54%	-3.76%	2.91%	-23.18%
FCF Yield	-37.15%	-20.17%	-7.01%	-3.51%	4.00%	-16.80%
Buyback Yield / Dilution	-0.17%	-1.04%	-12.34%	2.26%	-21.42%	-0.08%

Updated Sep 30, 2025. Source: S&P Global Market Intelligence. Standard template. Financial Sources.