Prothena Corporation Ratios and Metrics

Market cap in millions GBP. Fiscal year is January - December.

Millions GBP. Fiscal year is Jan - Dec.

Fiscal Year	Current	FY 2024	FY 2023	FY 2022	FY 2021	FY 2020
Period Ending	Jan '26 Jan 29, 2026	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021	Dec '20 Dec 31, 2020
Market Capitalization	346	595	1,531	2,582	1,700	351
Market Cap Growth	-40.76%	-61.12%	-40.69%	51.87%	384.06%	-26.36%
Enterprise Value	111	190	1,013	2,177	1,267	135
Last Close Price	6.36	10.50	28.72	49.63	31.29	8.72
PE Ratio	-	-	-	-	34.37	-
PS Ratio	39.42	5.51	21.34	57.70	11.48	562.08
PB Ratio	1.58	1.53	3.47	5.00	4.94	2.61
P/TBV Ratio	1.58	1.53	3.47	5.00	4.94	2.61
P/FCF Ratio	-	-	-	-	25.01	-
P/OCF Ratio	-	-	-	-	24.86	-
EV/Sales Ratio	12.94	1.76	14.12	48.66	8.55	215.82
EV/EBITDA Ratio	-	-	-	-	23.47	-
EV/EBIT Ratio	-	-	-	-	23.83	-
EV/FCF Ratio	-0.79	-	-	-	18.64	-
Debt / Equity Ratio	0.03	0.02	0.02	0.01	0.03	0.10
Debt / EBITDA Ratio	-	-	-	-	0.16	-
Debt / FCF Ratio	-	-	-	-	0.13	-
Asset Turnover	0.03	0.22	0.13	0.08	0.43	0.00
Quick Ratio	6.43	9.72	10.97	14.17	17.31	11.43
Current Ratio	6.61	10.01	11.24	14.34	17.48	11.58
Return on Equity (ROE)	-67.63%	-23.34%	-24.85%	-21.50%	20.61%	-48.65%
Return on Assets (ROA)	-29.31%	-15.54%	-16.42%	-12.03%	9.55%	-18.73%
Return on Capital Employed (ROCE)	-73.80%	-31.00%	-29.90%	-18.60%	12.50%	-36.70%
Earnings Yield	-60.36%	-16.41%	-7.54%	-3.76%	2.91%	-23.18%
FCF Yield	-40.51%	-20.17%	-7.01%	-3.51%	4.00%	-16.80%
Buyback Yield / Dilution	-0.17%	-1.04%	-12.34%	2.26%	-21.42%	-0.08%

Updated Sep 30, 2025. Source: S&P Global Market Intelligence. Standard template. Financial Sources.