IO Biotech, Inc. (IOBTQ)

OTCMKTS · Delayed Price · Currency is USD
0.0054
-0.0008 (-12.90%)
At close: Apr 27, 2026
Market Cap388.52K -99.3%
Revenue (ttm)n/a
Net Income-88.35M
EPS-1.34
Shares Out71.95M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume227,207
Average Volume34,805,341
Open0.0067
Previous Close0.0062
Day's Range0.0051 - 0.0067
52-Week Range0.0050 - 2.7900
Beta0.89
RSI22.95
Earnings Daten/a

About IO Biotech

IO Biotech, Inc., a clinical-stage biopharmaceutical company, develops immune-modulating therapeutic cancer vaccines based on the T-win technology platform. The company’s lead therapeutic cancer vaccine candidate includes IO102-IO103, which targets cancer cells and immune-suppressive cells in the tumor microenvironment that express indoleamine 2,3-dehydrogenase (IDO), and programmed death-ligand (PD-L1) that is in phase 3 clinical trial to treat melanoma, as well as in phase 2 clinical trial to treat lung, head and neck, and melanoma cancer. It... [Read more]

Industry Biological Products, Except Diagnostic Substances
Founded 2014
Employees 78
Stock Exchange OTCMKTS
Ticker Symbol IOBTQ
Full Company Profile

Financial Performance

Financial Statements

News

IO Biotech Provides Corporate Update

Raymond James engaged as financial advisor Reduction in force implemented NEW YORK, Jan. 30, 2026 (GLOBE NEWSWIRE) -- IO Biotech (Nasdaq: IOBT), a clinical-stage biopharmaceutical company developing n...

3 months ago - GlobeNewsWire

IO Biotech Announces Exploration of Strategic Alternatives

NEW YORK, Jan. 21, 2026 (GLOBE NEWSWIRE) -- IO Biotech (Nasdaq: IOBT), a clinical-stage biopharmaceutical company developing novel, immune-modulatory, off-the-shelf therapeutic cancer vaccines, today ...

3 months ago - GlobeNewsWire

IO Biotech Announces Publication of Five-year Clinical Outcomes of Phase 1/2 Trial in Nature Communications

Findings provide scientific insights into the contributions of IDO1 and PD-L1 vaccination to PD-1 blockade for the treatment of metastatic melanoma Five-year analysis of median progression free surviv...

4 months ago - GlobeNewsWire

IO Biotech Transcript: Piper Sandler 37th Annual Healthcare Conference

Phase III data for IO102-IO103 in melanoma showed meaningful PFS and OS trends with strong safety, though FDA BLA submission was not recommended due to statistical significance. New global trials and EU regulatory discussions are underway, with pipeline expansion and a solid cash runway into 2026.

5 months ago - Transcripts

IO Biotech Transcript: Evercore ISI 8th Annual HealthCONx Conference

The T-win platform demonstrated strong PFS benefits in melanoma, especially in PD-L1 negative patients, though the phase III narrowly missed statistical significance. Plans are underway for a larger, global phase III trial with updated comparators, while pipeline expansion and new trials in other cancers are progressing. Funding strategies include partnerships, especially in Europe.

5 months ago - Transcripts

IO Biotech Announces Participation in Upcoming December Investor Conferences

NEW YORK, Nov. 26, 2025 (GLOBE NEWSWIRE) -- IO Biotech (Nasdaq: IOBT), a clinical-stage biopharmaceutical company developing novel, immune-modulatory, off-the-shelf therapeutic cancer vaccines, today ...

5 months ago - GlobeNewsWire

IO Biotech Transcript: Jefferies London Healthcare Conference 2025

Cylembio's phase III trial in metastatic melanoma narrowly missed statistical significance but showed strong clinical benefit and safety, especially in key subgroups. A new global phase III trial with OPDIVO is planned, while expansion into lung and head and neck cancers and new targets continues.

5 months ago - Transcripts

IO Biotech Reports Third Quarter 2025 Financial Results and Provides Business Highlights

Topline data from Phase 3 (IOB-013) clinical trial in advanced melanoma presented at ESMO; data highlights improvements in PFS achieved in overall population and across virtually all subgroups, althou...

5 months ago - GlobeNewsWire

IO Biotech Announces Participation in Upcoming Investor Conferences

NEW YORK, Nov. 12, 2025 (GLOBE NEWSWIRE) -- IO Biotech (Nasdaq: IOBT), a clinical-stage biopharmaceutical company developing novel, immune-modulatory, off-the-shelf therapeutic cancer vaccines, today ...

5 months ago - GlobeNewsWire

IO Biotech Presents Pre-Clinical Data Highlighting the Potential of Additional Therapeutic Cancer Vaccine Candidates at the 2025 Annual Meeting of the Society for Immunotherapy of Cancer (SITC)

Pre-clinical data for IO Biotech's next T-win vaccine candidate, IO112 targeting arginase 1, demonstrates anti-tumor activity with dynamic changes in the tumor microenvironment (TME) driven by the vac...

6 months ago - GlobeNewsWire

IO Biotech Presents Phase 3 Results for Cylembio® plus KEYTRUDA® (pembrolizumab) in First-line Advanced Melanoma at ESMO 2025

Cylembio plus pembrolizumab achieved a clinically relevant 19.4 months median progression free survival (mPFS) compared to 11.0 months mPFS with pembrolizumab alone; study narrowly missed progression ...

6 months ago - GlobeNewsWire

IO Biotech Provides Update Following Pre-BLA Meeting with FDA

FDA recommends that IO Biotech not submit a Biologics License Application (BLA) based on the data from the IOB-013 clinical trial Company plans to design new registrational study for Cylembio for the ...

7 months ago - GlobeNewsWire

IO Biotech Announces Late-Breaking Abstract in Advanced Melanoma Selected for Oral Presentation at ESMO Congress 2025

Oral presentation will highlight the results from the randomized Phase 3 trial (IOB-013/KN-D18) of IO102-IO103 cancer vaccine plus pembrolizumab for first-line (1L) advanced melanoma Poster presentati...

7 months ago - GlobeNewsWire

IO Biotech Transcript: H.C. Wainwright 27th Annual Global Investment Conference

SilentBio™ showed strong clinical benefit in first-line advanced melanoma, with significant PFS improvement and a clean safety profile. Regulatory submissions are planned for late 2025 (US) and early 2026 (EU), with commercial readiness and pipeline expansion into additional indications.

8 months ago - Transcripts

IO Biotech Transcript: Morgan Stanley 23rd Annual Global Healthcare Conference

Lead program IO102-IO103 demonstrated a significant PFS benefit in advanced melanoma with a strong safety profile, and a BLA submission is planned by year-end. Additional updates from head and neck, lung, and neoadjuvant/adjuvant studies are expected, with launch and regulatory preparations underway.

8 months ago - Transcripts

IO Biotech Reports Second Quarter 2025 Financial Results and Provides Business Highlights

Announced clinical improvement in progression free survival observed in pivotal Phase 3 Trial of Cylembio® plus KEYTRUDA® (pembrolizumab) for the treatment of first-line advanced melanoma, but statist...

9 months ago - GlobeNewsWire

IO Biotech Transcript: Status Update

Cylembio™ plus pembrolizumab improved PFS in first-line advanced melanoma, with strong effects in PD-L1 negative patients and a favorable safety profile. The company plans to discuss these results with the FDA for a potential BLA submission by year-end.

9 months ago - Transcripts

IO Biotech's cancer vaccine shows improvement in late-stage study goal

IO Biotech said on Monday its experimental cancer vaccine, in combination with Merck's Keytruda, showed improvement in a late-stage study goal, but was not statistically significant.

9 months ago - Reuters

IO Biotech Announces Clinical Improvement in Progression Free Survival Demonstrated in Pivotal Phase 3 Trial of Cylembio® plus KEYTRUDA® (Pembrolizumab) for the Treatment of First-line Advanced Melanoma, but Statistical Significance Narrowly Missed

Patients treated with Cylembio (imsapepimut and etimupepimut, adjuvanted) plus pembrolizumab achieved improvement in progression free survival (PFS) compared to patients treated with pembrolizumab mon...

9 months ago - GlobeNewsWire

IO Biotech to Announce Topline Results of Pivotal Phase 3 Trial of Cylembio® in Combination with KEYTRUDA® (pembrolizumab) as a First-Line Treatment for Patients with Advanced Melanoma

NEW YORK, Aug. 10, 2025 (GLOBE NEWSWIRE) -- IO Biotech (Nasdaq: IOBT), a clinical-stage biopharmaceutical company, today announced the company will hold a conference call and webcast on Monday, August...

9 months ago - GlobeNewsWire

IO Biotech Transcript: Jefferies Global Healthcare Conference 2025

Cylembio, an off-the-shelf cancer vaccine, is positioned for a pivotal phase III readout in Q3 2025, with strong efficacy and safety data in melanoma, lung, and head and neck cancers. Market launch is targeted for 2026, with significant growth opportunities and high expectations from the medical community.

11 months ago - Transcripts

IO Biotech Transcript: TD Cowen's 6th Annual Oncology Innovation Summit

A pivotal phase III melanoma trial is on track for a Q3 2024 readout, with BLA submission planned by year-end and commercial launch targeted for 2026. Manufacturing and supply chains are secured, and the company is financially funded into Q2 2026.

1 year ago - Transcripts

IO Biotech Announces Participation in Cowen 6th Annual Oncology Innovation Summit and Jefferies Global Healthcare Conference

NEW YORK, May 20, 2025 (GLOBE NEWSWIRE) -- IO Biotech (Nasdaq: IOBT), a clinical-stage biopharmaceutical company developing novel, immune-modulatory, off-the-shelf therapeutic cancer vaccines, announc...

1 year ago - GlobeNewsWire

IO Biotech Reports First Quarter 2025 Financial Results and Business Highlights

Primary endpoint of pivotal Phase 3 trial (IOB-013/KN-D18) of lead investigational therapeutic cancer vaccine in patients with advanced melanoma still expected to readout in third quarter of 2025 Data...

1 year ago - GlobeNewsWire

IO Biotech Showcases Scientific Leadership Through Cancer Vaccines Educational Session at the American Association for Cancer Research (AACR) Annual Meeting 2025

NEW YORK, April 26, 2025 (GLOBE NEWSWIRE) -- IO Biotech (Nasdaq: IOBT), a clinical-stage biopharmaceutical company developing novel, immune-modulatory, off-the-shelf therapeutic cancer vaccines, today...

1 year ago - GlobeNewsWire