OPKO Health, Inc. (TLV:OPK)

Israel flag Israel · Delayed Price · Currency is ILS · Price in ILA
311.20
-5.80 (-1.83%)
May 15, 2026, 1:44 PM IDT
Market Cap2.41B -29.2%
Revenue (ttm)1.83B -15.7%
Net Income-672.24M
EPS-0.87
Shares Outn/a
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume117,125
Average Volume308,501
Open312.10
Previous Close317.00
Day's Range310.70 - 315.10
52-Week Range310.00 - 516.90
Beta1.41
RSI36.90
Earnings DateApr 28, 2026

About OPKO Health

OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company operates in two segments, Pharmaceutical and Diagnostics. The Pharmaceutical segment develops MDX2001, a tetra-specific antibody targeting several types of solid tumors in Phase 1 clinical trials; MDX2003, a tetra-specific antibody targeting two antigens for hematological tumors in Phase 1 clinical trials; and MDX2004, a trispecific immune modulator to rebuild and sustain the patient's own immune syst... [Read more]

Sector Healthcare
Founded 2006
Employees 2,275
Stock Exchange Tel Aviv Stock Exchange
Ticker Symbol OPK

Financial Performance

In 2025, OPKO Health's revenue was $606.88 million, a decrease of -14.90% compared to the previous year's $713.14 million. Losses were -$225.68 million, 324.0% more than in 2024.

Financial numbers in USD Financial Statements

News

OPKO Health's ModeX Therapeutics Will Present Data Demonstrating In Vivo CAR-T Cell Generation and Deep B-Cell Depletion in Preclinical Studies

Multispecific antibody conjugated LNP/mRNA platform enables in vivo T-cell engineering and systemic B-cell depletion in animal models  Data will be presented at the American Society of Gene & Cell The...

3 days ago - GlobeNewsWire

OPKO Health Expands Nicoya Agreement to Support RAYALDEE® Commercialization in Greater China

MIAMI, April 30, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) (OPKO) today announced that its subsidiary EirGen Pharma Limited (EirGen) has entered into an amendment to its agreement with ...

14 days ago - GlobeNewsWire

BioReference® Launches BioReference Direct™, Expanding Access to Consumer-Initiated Diagnostic Testing Through a Fully Integrated Digital Platform

ELMWOOD PARK, N.J., April 30, 2026 (GLOBE NEWSWIRE) -- BioReference® Health LLC, an OPKO Health, Inc. company and a trusted provider of diagnostic testing in the United States, today announced the lau...

15 days ago - GlobeNewsWire

Opko Health downgraded to Market Perform from Outperform at Barrington

Barrington analyst Michael Petusky downgraded Opko Health (OPK) to Market Perform from Outperform with no price target The firm previously had expected BRH break-even or profitability in 2026 and now…

15 days ago - TheFly

OPKO Health Earnings Call Transcript: Q1 2026

Q1 2026 saw progress in clinical pipeline, improved operating losses, and strong cash reserves. Diagnostics and pharma segments showed sequential and year-over-year improvements, with guidance reaffirmed for 2026. Partnerships and streamlined operations support future growth.

16 days ago - Transcripts

OPKO Health Reports First Quarter 2026 Business Highlights and Financial Results

MIAMI, April 28, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) (OPKO) reports business highlights and financial results for the three months ended March 31, 2026. Highlights from the first ...

16 days ago - GlobeNewsWire

OPKO Health's ModeX Therapeutics Begins Clinical Trial of Tetraspecific Antibody for Treatment of B-cell Lymphomas

Patients dosed in Phase 1 safety and tolerability study of MDX2003, a novel T-cell engager designed to optimize killing of lymphomas

23 days ago - GlobeNewsWire

OPKO Health to Report First Quarter 2026 Financial Results on April 28, 2026

MIAMI, April 21, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) plans to report operating and financial results for the three months ended March 31, 2026 after the close of the U.S. financia...

23 days ago - GlobeNewsWire

Opko Health price target lowered to $1.50 from $2.25 at Barrington

Barrington lowered the firm’s price target on Opko Health (OPK) to $1.50 from $2.25 and keeps an Outperform rating on the shares. The company reported a better than expected Q4…

2 months ago - TheFly

OPKO Health to Participate in the Jefferies Biotech on the Beach Summit

MIAMI, Feb. 27, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (Nasdaq: OPK) announced today that management will be participating in the Jefferies Biotech on the Beach Summit, being held March 10-11, 202...

2 months ago - GlobeNewsWire

OPKO Health Earnings Call Transcript: Q4 2025

Q4 2025 revenue declined year-over-year due to asset sales, but diagnostics and pharma segments showed operational improvements, with 4Kscore and international sales driving growth. Strong cash position supports R&D and accelerated share repurchases.

2 months ago - Transcripts

OPKO Health Reports Fourth Quarter 2025 Business Highlights and Financial Results

MIAMI, Feb. 26, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) (OPKO) reports business highlights and financial results for the three and 12 months ended December 31, 2025, and introduces fi...

2 months ago - GlobeNewsWire

OPKO Health to Report Fourth Quarter 2025 Financial Results on February 26

MIAMI, Feb. 12, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) plans to report operating and financial results for the three and 12 months ended December 31, 2025, after the close of the U.S...

3 months ago - GlobeNewsWire

Opko Health Entera Bio, Entera Bio expand partnership to advance PTH tablet

OPKO Health (OPK), through its wholly owned subsidiary, OPKO Biologics, and Entera Bio (ENTX), announced the expansion of their 2025 Collaboration and License Agreement to advance the first oral long-...

3 months ago - TheFly

OPKO Health and Entera Bio Expand Partnership to Advance First-in-Class Oral Long Acting PTH Tablet for Patients with Hypoparathyroidism

This is the third  program that s uccessfully combine s Entera's oral peptide N- Tab ® platform with OPKO 's advanced protein chemistry capabilities

3 months ago - GlobeNewsWire

OPKO Health Transcript: 44th Annual J.P. Morgan Healthcare Conference

The company has restructured to focus on therapeutics, divesting diagnostics for profitability and advancing a robust pipeline through partnerships with Merck, Regeneron, and BARDA. Key assets include a Merck-partnered EBV vaccine, multi-specific antibodies, and a growing diagnostics business centered on the 4Kscore test.

4 months ago - Transcripts

OPKO Health to Participate in the 44th Annual J.P. Morgan Healthcare Conference

MIAMI, Jan. 06, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (Nasdaq: OPK) announced today that management will be participating in the 44th Annual J.P. Morgan Healthcare Conference, being held January...

4 months ago - GlobeNewsWire

Opko Health initiated with a Neutral at JPMorgan

JPMorgan initiated coverage of Opko Health (OPK) with a Neutral rating and no price target The firm says Opko is a “multi-faceted” healthcare company, focusing in clinical diagnostics services through...

6 months ago - TheFly

OPKO Health to Participate in the Piper Sandler 37th Annual Healthcare Conference

MIAMI, Nov. 19, 2025 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (Nasdaq: OPK) announced today that management will be participating in the Piper Sandler 37th Annual Healthcare Conference, being held Decemb...

6 months ago - GlobeNewsWire

Opko Health downgraded to Hold from Buy at Jefferies

Jefferies downgraded Opko Health (OPK) to Hold from Buy with a price target of $1.60, down from $2. The firm, which is lowering Ngenla out-year estimates, says Opko’s drug pipeline…

7 months ago - TheFly

Opko Health reports Q3 EPS 3c, consensus (5c)

Reports Q3 revenue $151.7M, consensus $165.74M. The company said, “Consolidated total revenues for the third quarter of 2025 were $151.7 million compared with $173.6 million for the comparable period ...

7 months ago - TheFly

OPKO Health Earnings Call Transcript: Q3 2025

Q3 2025 saw strong execution on strategic priorities, including the sale of oncology assets, robust cash position, and significant R&D progress. Diagnostics and pharma segments showed improved profitability, with BioReference and ModeX clinical programs advancing and new partnerships fueling future growth.

7 months ago - Transcripts

OPKO Health Reports Third Quarter 2025 Business Highlights and Financial Results

MIAMI, Oct. 29, 2025 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) (OPKO) reports business highlights and financial results for the three and nine months ended September 30, 2025. Highlights fro...

7 months ago - GlobeNewsWire

Opko Health’s ModeX enters license, collab agreement with Regeneron

ModeX Therapeutics, an OPKO Health company (OPK), announced that it has entered into a license and collaboration agreement with Regeneron Pharmaceuticals (REGN) to discover and develop multispecific a...

7 months ago - TheFly

Opko Health’s ModeX Therapeutics begins trial of MDX2004

ModeX Therapeutics, an OPKO Health (OPK) company, announced the initiation and recent dosing of the first patient in a Phase 1/2a clinical trial with MDX2004, a first-in-class trispecific antibody-fus...

7 months ago - TheFly