Thank you for joining Healwell AI's first quarter 2025 financial results conference call. All participants are in listen-only mode, and the conference is being recorded. After the presentation, there will be an opportunity for analysts to ask questions. To join the question queue, you may press star, then one on your telephone keypad. Should you need assistance during the conference call, you may signal an operator by pressing star, then zero. I will now turn the call over to Pav Sangha, Investor Relation at Healwell. Please go ahead.
Hello. Thank you, Operator. Joining me on the call today are Dr. Alexander Dobranowski, CEO of Healwell AI, and Anthony Lam, the company's CFO. I trust that everyone has received a copy of our financial results press release that was issued earlier today. Listeners are also encouraged to download a copy of our quarterly financial statements and management discussion and analysis once filed on SEDAR+ . Please note portions of today's call, as known historical performance, include statements that are forward-looking information within the meaning of applicable securities laws. These statements are made under the safe harbor provisions of those laws. Please refer to today's press release and to our management discussion and analysis for more details on the company's risks and forward-looking statements. We provide forward-looking statements solely for the purpose of providing information about management's current expectations and plans relating to the future.
We do not undertake or accept any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements to reflect any change in our expectations or any change in events, conditions, assumptions, or circumstances on which any such statement is based, except if it is required by law. We use terms such as gross margin and adjusted EBITDA on this conference call, which are non-IFRS and non-GAAP measures. For more information on how we define this term, please refer to the definition set out in our management discussion and analysis. There will be a question-and-answer session at the end of this call, which will be limited to analysts only. To ask a question, analysts are required to call into the conference call using the dial-in number provided in our press release. With that, let me turn the call over to Dr. Alexander Dobranowski, CEO.
Thank you, Pav. Good day, everyone, and thank you very much for joining us today for our Q1 2025 conference call. We're very pleased with our Q1 results, in which we achieved revenue from continuing operations of CAD 14.1 million, an increase of 208% as compared to Q1 2024. We accomplished these impressive results all the while our primary focus in Q1 was actually on securing the financing for and implementing the transformational acquisition of Orion Health, which closed on April 1. With the addition of Orion Health, we have now entered a very new and exciting phase for Healwell. I will share more details about Orion Health shortly and want to remind everyone that Orion Health's financials will be included in our results starting next quarter in Q2. Our Q1 results do not reflect the current strength of our combined business with Orion Health.
On today's call, I'd like to focus on three key topics: one, the underlying strength in our Q1 results; two, a bit more about the Orion Health acquisition; and three, the strategic changes and additions to our executive team. Let's start with our Q1 results. I'm pleased to share our strong Q1 results, which reflect continued momentum across our business. Our Q1 reflects the strength and diversification of Healwell AI's business as we continue to scale a category-defining AI-powered healthcare platform. The momentum in our AI and data science division is especially exciting. Cure Health has seen rapid adoption from major healthcare stakeholders, while Pentavere is gaining traction with new enterprise wins. These technologies are fundamentally reshaping how at-risk patients are identified, understood, and their care compliantly optimized across the healthcare system.
During the first quarter, we delivered strong revenue and gross profit attributable to the growth and commercialization of our AI and data science solutions and our recent acquisitions of BioPharma Services and Verisource. In Q1, Healwell's two AI subsidiaries, Pentavere Research and Cure Health, continued to experience strong growth in the number of master service agreements signed, highlighting the increasing demand for their AI-driven solutions in the life sciences sector. By the end of Q1 2025, these two subsidiaries had a combined total of 32 signed MSAs. This reflects substantial growth compared to the 16 cumulatively signed MSAs at the end of Q1 2024. Now, with regards to our growing impact on patient outcomes, in Q1, Healwell identified approximately 50,800 high-risk patients, a substantial increase from the 43,000 high-risk patients identified in Q4 2024.
This highlights our progress as we execute against our mission of early disease detection and identifying gaps in care. We are very proud of our accomplishments to date in healthcare artificial intelligence and data science. I'll now expand on our second key topic, Orion Health. Subsequent to quarter end, we completed the transformative acquisition of Orion Health, a global leader in healthcare data interoperability, marking our transition into a truly global company. This acquisition significantly expands our international presence, adding over 70- key customers across 11 countries and nearly 400 skilled team members to our organization. Orion Health also provides us with robust healthcare data infrastructure, strong operating margins, and strong free cash flow conversion, substantially enhancing our financial profile. Our vision is to integrate Orion Health's powerful healthcare data platforms with Healwell's advanced AI technologies, thereby building a unified global platform that enhances efficiency and improves patient outcomes.
Orion's established presence in the public sector strengthens our relationships with government partners, while its extensive customer base provides a valuable new channel for distributing our AI solutions worldwide. This acquisition marks a very pivotal milestone for Healwell, positioning us to deliver more holistic, data-driven healthcare solutions globally. Leveraging Orion's global reach and robust data infrastructure, we are now better equipped to transform healthcare through AI and data science. With a focus on enabling integrated data-driven care, Orion Health's core platforms, the Amadeus Digital Care Record and the Virtuoso Digital Front Door, are designed to support seamless healthcare delivery across entire health systems. These solutions enable better coordination of care, enhancing patient outcomes while driving efficiencies. Orion Health's impact spans both private and public sector clients, reinforcing its position as a trusted partner in transforming global healthcare. I'll now highlight some of Orion Health's key deployments around the world.
In Ontario, Orion Health has delivered one of the largest digital front door programs in North America, supporting a population of over 15 million people. This initiative aligns with the government of Ontario's digital-first health policy, which has fundamentally transformed care delivery by expanding access to digital and virtual care options. The DFD implementation provides users with 24/7 access to reliable health information and appropriate health services, significantly reducing the burden on emergency healthcare. In addition, delivery is underway for a province-wide digital care record that will unify clinical data across the continuum of care. In addition to Ontario, sorry, Orion Health has also deployed its digital front door solution in Newfoundland as a native mobile app for personal health records and services. In Alberta, Orion Health has maintained a 20+-year partnership, enhancing collaboration between clinicians across hospital and community care settings.
This includes one of Orion Health's largest digital care record implementations, with over 1.2 billion clinical screen views and 70,000 clinical users. Internationally, in Saudi Arabia, Orion Health powers the largest digital care record deployment in the world, covering a population of 35 million. It aggregates data from more than 5,000 government and private healthcare providers to deliver a single longitudinal view of every patient's care journey. In Abu Dhabi, Orion Health delivered the first digital care record deployment in the Middle East, connecting 100% of hospitals, clinics, and pharmacies in the region. Orion Health's reach also extends to the United States, where it provides digital care record infrastructure for statewide and regional health information exchanges, or HIEs, in states like Maine, Minnesota, Pennsylvania, New Mexico, North Dakota, and Idaho.
In the United Kingdom, Orion is rolling out digital care records across 10 of the 42 integrated care boards as part of the national shared care record initiative. Finally, in New Zealand, the headquarters of Orion Health, Orion works with Southern Cross to streamline over 80,000 patient admissions annually across 16 hospitals using both its digital front door and digital care record solutions. This is a truly global footprint built on modern interoperable standards and supported through deep partnerships, including being an AWS advanced tier partner in healthcare. Orion's solutions are embedded in the core infrastructure of healthcare delivery with long-term contracts and critical functionality that makes it very difficult to displace. Now, with Healwell's advanced AI capabilities combined with Orion's global scale, we are uniquely positioned to drive innovation at the intersection of data interoperability and artificial intelligence.
Our unified platform will enable intelligent care coordination, predictive insights, and AI-powered workflows that transform healthcare delivery, improving outcomes and optimizing system efficiency. By leveraging Healwell's deep AI expertise alongside Orion Health's cutting-edge R&D, we will significantly enhance the Virtuoso Digital Front Door and Amadeus Digital Care Record platforms, empowering healthcare organizations worldwide. We're already working together on high-impact integration opportunities across our businesses, and we look forward to the bright future ahead. I'll now discuss the recent strategic changes and additions to the executive leadership team. With the acquisition of Orion Health now closed, we shift to the next phase of our growth and integration. As part of this, we've also strengthened our leadership team with world-class talent.
Effective July 1, James Lee will be appointed CEO, while I will transition to the role of President, continuing my work as a member of the board of directors, and I will continue to drive critical leadership functions for the company. Additionally, I will also be focused on the acceleration of the company's AI and data science solutions with large enterprise customers, as well as continuing to lead the company's capital markets activities. James is a highly accomplished executive with over two decades of experience leading multinational organizations, most recently as CEO of Jarden New Zealand, and since joining Healwell earlier this year as Chief Strategy Officer, James has played a critical role in shaping our integration plans and aligning the organization for scale.
I have tremendous confidence in his ability to lead Healwell through this next chapter of growth and innovation, especially as we continue to see stronger-than-expected progress across the business. Looking back, I'm extremely proud of what we've accomplished so far. In just 19 months, we completed six strategic acquisitions. We've raised over CAD 100 million in capital. By our estimations, we are one of the fastest-growing healthcare AI companies globally, and our momentum continues to exceed expectations, a testament to the strength of our vision and the exceptional execution of our team. We're also very excited to welcome Sasha Gurzhiev as Chief Operating Officer and Brad Porter as Chief Commercial Officer. Both bring deep expertise and execution, which will be key in accelerating our growth. Sasha brings an outstanding track record in scaling SaaS technology and cybersecurity businesses globally and will lead day-to-day operations, technology strategy, and alignment across divisions.
His focus on organizational efficiency and execution will be critical as we integrate Orion Health and scale our commercial operations. Sasha is replacing our former co-Chief Operating Officers, Adam and Paolo, and we thank them both for the incredible work done over the last year and a half. In addition, Brad Porter, who currently serves as the CEO of Orion Health, has now taken on the additional and expanded role of Chief Commercial Officer at Healwell. Brad has extensive experience in global healthcare commercialization, and his leadership will be instrumental as we bring our AI capabilities to new markets, particularly in the public sector and across government healthcare systems. He will continue to lead Orion Health while also overseeing our group-wide global commercial strategy.
In this critical role, Brad will drive the distribution of Healwell AI's capabilities across the Orion Health network with a strong focus on public sector opportunities and government contracts. These leadership changes reflect our commitment to building a world-class, mission-driven leadership team capable of scaling Healwell to new heights. Our focus is now squarely on integration, product expansion, and commercial execution at scale, capitalizing on the significant market opportunities presented by the Orion Health acquisition. Our transition from an M&A-driven strategy to one focused on operational excellence and scalable growth is already delivering results, with progress across the business exceeding our expectations. I am truly energized by what's ahead and look forward to continuing to work closely and supporting James Lee and the rest of our executive team as we push the boundaries on what's possible in healthcare AI.
Further to the additions and changes with management, we have also warmly welcomed three directors to our board: Ian McCray, a globally recognized technology entrepreneur and the founder of Orion Health; Tina Raja, bringing deep sector experience in U.S. growth and private equity and capital markets; and Sam Engelbart, co-founder and partner at Galaxy Digital Holdings. We also thank departing directors Kingsley Ward and Bashar Al-Rahani for their dedicated support during their tenure. With that, I'd now like to turn the call over to our CFO, Anthony Lam, to walk you through the Q1 financial results further.
Thank you, Alex. Before I begin, I'd like to remind everyone that all of the figures I will be discussing today are in CAD, and our financial statements are presented in accordance with IFRS International Financial Reporting Standards.
Our first quarter 2025 results are as follows: Healwell achieved quarterly revenues of CAD 14.1 million during Q1 2025, compared to revenue of CAD 4.6 million generated during Q1 2024, an increase of 208%. The acquisitions we made in 2024 are all positively impacting the growth of our revenue for the company. Organic growth from the businesses we owned in the healthcare software and data AI segments, which include Cure, Pentavere, and IntraHealth, was 51%. Organic growth in our clinical business was relatively flat at 6%. Our acquired businesses, Verisource, BioPharma, and MedChart, added approximately CAD 6.4 million in revenue in the quarter. Healwell achieved gross profit of CAD 6.5 million in Q1 2025, an increase of 226%, compared to CAD 2 million during Q1 2024. The increase in gross profit is mainly driven by higher revenues. Healwell's gross margin percentage in Q1 2025 was 46%, compared to 44% in Q1 2024.
The increase in gross margin was also primarily due to the contribution of higher margin revenues from Verisource, IntraHealth, and Mutuo. Margin profiles in these businesses averaged over 50%. During Q1 2025, Healwell reported adjusted EBITDA loss of CAD 3.3 million, compared to an adjusted EBITDA loss of CAD 2.5 million in Q1 2024. The greater loss was due to higher losses in our AI subsidiaries, investments in scaling our business, and higher marketing and awareness expenditures. Healwell reported CAD 14.1 million in net loss for Q1 2025, as compared to a loss of CAD 6.3 million in Q1 2024. The higher loss is due to CAD 2.5 million in transaction-related costs related to the Orion Health acquisition and CAD 2.9 million in stock-based compensation expense on a year-over-year basis. I will now provide an update on our cash and debt position.
We ended the quarter on March 31st, 2025, with CAD 18.4 million in cash, an increase as compared to CAD 9.4 million at the end of Q4 2024. The company also had CAD 86.6 million of cash that was held in escrow in advance for its acquisition of Orion Health, which subsequently closed on April 1, 2025. During the quarter, the company implemented targeted cost optimization efforts, including a workforce reduction, which are expected to result in CAD 3 million of annualized savings, further strengthening our financial position moving forward. In total, we secured CAD 100 million in total financing to support the acquisition of Orion Health, comprising CAD 50 million in credit facility led by Scotiabank and RBC, and CAD 55.5 million in capital from a bought deal financing, which included CAD 30 million in convertible debentures and CAD 25.5 million in equity.
I want to spend a few minutes now talking about our overall growth and profitability outlook for 2025, including our individual revenue segments. We're expecting healthy organic growth across all business units in 2025. In addition, Orion Health will have a significant positive contribution to our financial results, adding approximately CAD 100 million in annual top-line revenue starting in Q2 2025. With the benefit of our cost optimization efforts in the Orion acquisition, we expect to be adjusted EBITDA positive for the full year of 2025. The company generates revenues in three distinct segments: one, AI and data science; two, healthcare software; and three, clinical research and patient services. The first is AI and data science, which includes our AI-centric divisions, Pentavere, Cure Health, and Mutuo.
All AI and data science segments achieved our AI and data science segment achieved CAD 2.3 million in Q1 2025 revenue, an impressive 224% revenue growth on a year-over-year basis versus the prior year. Our AI and data science division serves a clientele of life sciences, pharmaceutical, medical device, and precision medicine companies. We're expecting our AI and data science segment to achieve 100% growth in 2025. Our second revenue stream is healthcare software revenue provided by IntraHealth, an enterprise-grade EHR platform, Verisource, an end-to-end customizable cloud-based healthcare data interoperability platform. This segment generated CAD 5.7 million in revenue in Q1, a significant increase from CAD 2 million in revenue in the same quarter of last year. Our healthcare software division serves a clientele of public sector healthcare systems, healthcare providers, hospitals, and clinics. Going forward, Orion Health's financial performance will be added to the healthcare software segment.
This will have an immediate impact on our financial performance starting in Q2 2025, as it will add, as I mentioned earlier, up to CAD 100 million in top-line revenue starting in Q2. This substantially has an impact on our business and our full year results, and we expect to see our healthcare segment to make up over 70% of the company's total revenue for the year. The third revenue segment of clinical research and patient services consists of clinical research delivered by Biopharma and Canada Phase Onward, as well as our outpatient polyclinic business. Clinical research revenues are contract-based revenues. This segment operates on a per-visit project basis and has a track record of positive EBITDA. It also caters to diverse clientele, including government reimbursement, health insurance reimbursement, and life science research sectors.
This segment generated CAD 6.1 million of revenue in Q1 2025, an increase of 233%, as compared to CAD 1.8 million in Q1 2024. This boost in revenues is attributed to the acquisition of Biopharma Services. To build on comments that Alex made earlier, our acquisition of Orion Health positions Healwell AI to drive innovation at the intersection of data interoperability and artificial intelligence. As this year progresses, AI and data science, along with healthcare software, will approach 80% of the company's total revenue. Leveraging Orion Health's global reach, robust data infrastructure, and install base, Healwell AI is poised to deploy more of its AI and data science capabilities across the existing and new relationships. In summary, I'm pleased to report that Healwell AI's outlook is bright. The company is in a strong financial position and has the capital to fund future tuck-in acquisitions and can execute on its organic growth initiatives.
We look forward to reporting Q2 results with the consolidated results of the Orion Health business. Most importantly, we are well-positioned to be profitable on an adjusted EBITDA basis going forward and supporting our strategic focus on sustainable, profitable growth. I will now turn the call back over to Alex.
Thank you very much, Anthony. Before closing, I wanted to say a few comments about the potential impact of tariffs on our business and the Buy Canadian opportunity. We believe the growing momentum behind the Buy Canadian initiative presents a significant opportunity for Healwell AI to expand its role in Canada's healthcare ecosystem. With provinces now prioritizing Canadian suppliers in response to U.S. tariffs, demand for homegrown healthcare solutions is rising. Healwell is uniquely positioned to support this shift, providing advanced, made-in-Canada health technology solutions that are already integrated into health systems across multiple provinces.
This Canadian presence is now further strengthened by Orion Health, a leader in provincial health information exchange platforms, supporting integrated health information access across several provinces and territories. Orion also has a strong presence in public health and is at the forefront of digital front-door solutions, as I mentioned, partnering with the governments of Ontario, Newfoundland and Labrador to enhance care access to 16.5 million Canadians. As governments seek to strengthen domestic healthcare infrastructure, Healwell's expertise in health information exchange, AI-powered solutions, and digital health platforms positions us as a key partner. Increased engagement at both the provincial and federal levels further reinforces our strategic position as policymakers look to reduce reliance on foreign technology and expand public sector partnerships. Now, I'd like to share some insights on our goals for the rest of the year for 2025.
We are continually seeing unprecedented opportunities in healthcare data science and artificial intelligence, and our advanced AI copilot technology is at the forefront of this evolution. Our commitment to enhancing healthcare delivery through innovative technology remains unwavering, and we are poised to drive substantial value for our stakeholders. Our goals for 2025 are as follows: one, integration of Orion Health with the rest of the Healwell AI business; two, continue to execute on our M&A strategy. The company's growth and progress is underpinned by our continued focus on accretive and disciplined capital allocation; three, accelerating organic growth by ramping up physician adoption of the Healwell AI platform; four, continuing to deepen our integration and broadening our reach within the WELL Health ecosystem; and five, leverage our Canadian footprint and the WELL Health relationship to take advantage of the Buy Canadian opportunities in healthcare.
Overall, our focus is firmly on sustainable growth and delivering impactful results for our stakeholders, patients, and the broader healthcare community. We have an extremely positive outlook based on our organic growth profile and our M&A strategy. In closing, I want to reiterate that Healwell is a healthcare artificial intelligence company that has globally validated artificial intelligence, with now over 30 signed MSAs with life sciences partners. The Orion acquisition, which closed on April 1, boosts Healwell's revenue by approximately CAD 25 million per quarter and turns the company into an EBITDA positive business. The WELL Health relationship accelerates our growth with exclusive access to providers across North America. M&A will continue to play a significant role at Healwell going forward. Including Orion Health, we have completed six key transactions to date.
We believe that we have the necessary building blocks in place to successfully execute in healthcare AI, and not just in Canada, but also from a global perspective. Finally, I want to thank the entire team at Healwell, whose hard work continues to elevate the company. I'd like to thank our investment banking partners. I would like to thank our Chairman, Hamid Shabazi, and the leadership team at WELL Health. Plus, I would like to thank my board of directors, and I'd like to thank all of you for joining the call today, and we look forward to providing an exciting update next quarter. I'll now hand it back to the operator.
Thank you. We will now begin the analyst question and answer session. To join the question queue, you may press star, then one on your telephone keypad. You will hear a tone acknowledging your request.
If you're using a speakerphone, please pick up your handset before pressing any keys. To withdraw your question, please press star, then two. The first question comes from Kevin Krishnaratne with Scotiabank. Please go ahead.
Hey there. Good afternoon. I've got a few questions on data and AI. So good performance sequentially. It's still very early days. First question, can you talk about any ways to break down that revenue? I know, Anthony, you talked about pharma, life science, medical device, and precision, but what about the healthcare practitioner side on the clinical support? Is that being monetized? If so, how much of the mix does it make up? And then you can talk about maybe how much of that revenue is recurring in nature.
Hey, Kevin, thank you for joining. Thanks so much for the question. I'll just quickly clarify.
With stakeholders that we work with, our partners in the physicians, providers, and provider networks and hospitals, we do not monetize through those stakeholders at all. We provide our tools to then provide them with support, clinical decision support, so they can make more informed decisions. That is not part of that mix of revenue. Where we are now currently commercializing our AI technologies is largely through our life sciences partners. Also now we are looking at a number of exciting opportunities with other large enterprises and, of course, public sector. I will add, Kevin, to your question on recurring. We are, I would say, between 5% and 8% recurring right now on some of that AI business. It is still a small portion of it, but we are starting to see some recurring nature of it.
Got it. That is helpful. Then, yeah, Alex, I definitely had the question.
You called it out a few times, enterprise clients. You've got 32 MSAs. Maybe talk about what you're seeing there. Again, it's still super early days, but what would it take for us to start to see the real bigger jumps in revenue here? I mean, no doubt you've got the top 10, 20 life science companies, and these customers spend a lot of money on commercial efforts. What do you see as the tipping point where you really start to unlock a lot more bigger mandate? Maybe talk about the nature of these 30+ MSAs you've got.
Sure. Kevin, I'll answer that. What we're starting to see now is demonstrating value towards every stakeholder that's part of the healthcare ecosystem collectively.
As we execute against this mission of early disease detection and finding high-risk patients, yes, number one, we're identifying gaps in care, and we're providing insights, which helps them then be on an optimized care path journey. Number two, we're starting to do it at a quantum where we're going to be able to start measuring the results, as in what is the actual cost saving to the healthcare system, both locally and in some of the other jurisdictions that we work in. Those types of insights are then, in turn, very helpful with discussion, for instance, with public sector customers. We're also exploring, well, what are some of the benefits here and insights for the insurance sector? That's kind of another category that we're looking at very carefully.
With life sciences, remember, this is about making sure that patients have ultimately access to life-saving interventions and also access to clinical research, which, again, can in some ways also be life-saving. These are the ways, the drivers of how we're demonstrating value to all these stakeholders. Kevin, to be a bit more precise, we're noticing, especially with our life sciences partners, that they're very satisfied with this type of value that we're demonstrating, and we're continuing to grow our work with each individual customer as we move forward.
That's helpful context. Thanks. Alex, just the last one for me. When it comes to the tech in your data and AI segment, you've got, I think, over 100 algorithms now. Can you remind us of the strategy? I know M&A is going to be a part of that.
How do you think about what would make logical targets? Is it sort of your pharma client customers helping you figure out what are priorities? Are there certain areas of, I do not know, disease or health conditions that just make for a more natural fit alongside your current portfolio? When you are looking at targets, how do you think about what makes a potential target good versus bad? I am just trying to get a sense of, I know it is a smaller piece of your M&A strategy, but I think it is an important underlying tech piece. Thanks.
No, this is actually a very, very important area of our focus. Kevin, what actually drives some of where we focus capability acquisition is where are some of our gaps?
Currently, as you mentioned, we have capabilities where we can screen now for over 100 different conditions, but there are certain disease areas where we're not screening at all. For instance, one domain is particularly in dermatology and skin-related conditions. That is somewhere where we're looking a little bit more closely as, okay, are there opportunities there to bring in some technology that closes that gap? That is number one. Number two, we also look at, okay, where are the biggest burdens of some of these conditions in different population cohorts? We're looking at increasing amounts of, for instance, cognitive decline in dementias, etc. That may be an area of focus. Of course, the very large burden in metabolic disease.
That is another domain where we are looking at different capabilities, which may make sense to bring under the Healwell umbrella and tie together with our clinical decision support platform.
Got it. Thanks so much. I will pass the line and congrats on a great start to the year.
Thank you so much, Kevin.
The next question comes from Doug Taylor with Canaccord Genuity. Please go ahead.
Hi, thank you. You started or you finished your prepared remarks by talking about some of your key goals for this year, the first being the integration of Orion. I wanted to ask a question about that. I know it has been just a month since that acquisition closed in its early days.
As you look at over the coming quarters, could you speak to what some of the primary milestones that the management team is focused on internally around that integration and what we can look for as confirmation that the business is tracking to your plans?
Sure, Doug. Thank you so much. Thanks for attending and, of course, the question. Look, the integration of Orion is cornerstone now to our strategy in 2025. I'll just reiterate quickly because the theme here is, okay, on one hand, we have globally validated artificial intelligence capabilities. We can help us screen patient cohorts and help identify gaps in care. That's number one. Number two, Orion Health now has scaled data infrastructure and software into a number of key geographies, etc.
Orion Health and the leadership team there is seeing that there is demand for more sophisticated tooling for their customers to be able to understand the data that they steward better. Number one, you are going to see us communicate in the coming quarters of our integration efforts of actually doing that, plugging in some of our AI capabilities into the Orion Health footprint for them to be able to serve their customers better. That is something that is really kind of top of mind. Number two, there is a whole host of other revenue synergies that we will be working on. Of course, also some cost synergies too. I will just add this, Doug, that concurrent to the closing of this acquisition, of course, WELL Health exercised their option to acquire more voting shares.
We have an opportunity now with some cost optimization, not just between Healwell and WELL Health, but through some support of their shared services also to the Orion Health level. It is really early days. We have just been about five or six weeks since we closed this acquisition, but we have hit the ground running.
I appreciate all that. Thank you. You also recapped a number of senior management appointments that were announced over recent months. Certainly, you have expanded the management team. Is that team now set at this point, or is there more augmentation left to be done here?
Doug, with the team we had in place, Anthony Lam, Blake Corbett, my former co-Chief Operating Officers, what we wanted to do now concurrent with the close of April 1 is now make sure that we added the capabilities and the talent to really take this company forward and to be a player globally. We are really excited about adding Sasha Gurzhiev, our Chief Operating Officer, Brad Porter, also with an expanded role and his deep pedigree of growing healthcare-oriented companies globally. Of course, James Lee, who is replacing me as CEO, has a very tremendous background and reputation. This is all about now anchoring together to really take this company to the next level. To answer your question, yes, this is the composition that we think we have needed and the composition that we wanted to make sure that we are going to be successful.
Okay.
Maybe one last question for me. I'll ask a question on BioPharma and that business unit. I mean, you've spoken in the past about your strategy to transition to higher margin, later stage trials, and stabilize, and then ultimately grow that revenue base, which is still going to be maybe a quarter of the pro forma overall revenue total. Can we talk about where you are on that process? Has there been any movement of late?
Yes, for sure, Doug. I'll also add, part of the strategy and thinking with the CRO BioPharma is also the greater connection to the WELL Health ecosystem and clinic footprint.
What we're working on here is a multi-phase, multi-quarter effort where we would like BioPharma as an anchor to carefully transition to also offering, besides preclinical and phase I clinical research services, also adding later phase trial work. That is really so that we can offer the service to, of course, our partners at WELL Health and then, of course, other healthcare systems, etc. We have undergone two major steps here. Number one is we did do some cost optimization, Doug. On top of that, we've now reoriented with an effort to grow sales and added sales capacity and talent. You'll see us in the coming quarters demonstrate some progress here, but that's what we've done to date. Look, we're steering this asset and executing quite carefully because we've identified a tremendous opportunity, but there are, of course, a few moving parts.
Okay. We'll look forward to hearing more about that in the quarters ahead. I'll pass the line. Thank you.
Thanks, Doug.
The next question comes from Alan Cleve with Maxim Group. Please go ahead.
Yes. Hi. Just following up on the last question. For your CRO business, last quarter, you talked about how it would be a little lighter in the first half, but then pick up in the second half as you go to later stage. Do you still feel that way?
Great question. Yes. I mean, that is how we see the business. It performed exactly how we expected in Q1. I think our comments are in line with our expectations at the moment.
Okay. Great.
My second question, this is really dumbing it down, very similar, but if you had an EBITDA loss of close to CAD 3 million this quarter, and if you add Orion, which is going to do around CAD 6 million in EBITDA a quarter, does that kind of imply you're starting off around CAD 3 million, but then it should potentially grow quarterly as your businesses grow? Is that the simple way, or am I missing something?
Alan, I think we feel that the addition of Orion adds on an annual basis CAD 100 million of top-line revenue for us on an annualized basis starting in Q2. We also see the addition of Orion helping us move into the positive EBITDA for the full year. That's how we see the business right now, and we're excited about it.
Okay. Thank you very much.
The next question comes from Brian Kinstlinger with Alliance Global Partners. Please go ahead.
Great. Thanks so much. Your AI offering has grown 100% in just the last six months. Congratulations. I'm hoping you can speak to customer concentration within this offering, maybe share what the top two or three customers account for as a percentage of this segment. I'm curious, maybe you can take us along what the evolution of those customers look like in terms of taking on additional disease algorithms or how volumes within one disease might increase over the course of 12 to 18 months.
Sure. I'd love to expand on this. Thanks for the question. In terms of customer diversification, it's actually quite high. We're now commercially active with a number of our partners in the life sciences sector.
We're now also starting to explore some fairly exciting work also in the public sector, but there's no concentration of one or two names taking up a material amount of kind of the shared pie. Sorry, what was the second question?
I'm curious when a customer takes over.
Oh, yeah. Sorry. Over time.
Yeah.
Yeah. Okay. Understood. Look, what we've seen is we've gone from some very small initiatives, and we've, in fact, more often than not, or largely the entire time, have expanded our initiatives with each customer. What we're noticing is that we're able to now demonstrate ROI, we're able to demonstrate competency, and we're able to grow these relationships customer by customer. It's really, really encouraging. As Anthony mentioned as well, some of these customers now, we're actually working in a recurring format with them.
There aren't too many healthcare AI companies globally that have actually kind of gotten to that level of competency through validation and, of course, building trust.
Okay. By the way, just to be clear, I don't know what's meaningful to you. There's no one customer that represents, say, 20% of AI revenue. Is that right?
That's correct.
Okay. My follow-up is you mentioned 51,000 cases, I think, of early disease detection in the first quarter. Again, you've got 100-some algorithms checking diseases. Are there, in that case, any one or two or three diseases that are dominating your case detection or your revenue generation thus far?
The answer is no, but I will just explain our areas of focus right now are in the rare disease space, the ultra-rare space, chronic disease, which is, of course, paramount and most important.
We've also done some work in cardiovascular disease and, of course, really importantly, in oncology. There's no one kind of area I'd point you to and say, "Hey, this is an outsized amount of focus."
Okay. Those are all my questions. Thank you.
Thank you very much.
The next question comes from Gianluca Tucci with Haywood Securities. Please go ahead.
Hi. Good afternoon, guys. Congrats on the quarter. Maybe I'll just start off with a high-level question. In these early days of cross-selling AI into the Orion Health customer base, could you speak to how sales cycles are looking over there or compared to what you're used to previously?
Sure. Gianluca, thanks very much for attending and the question. What's interesting here is that the Orion Health customer base, which is fairly sophisticated, these are largely public sector customers, they're actually looking for additional capabilities.
Largely, these are capabilities that Healwell can provide. We are not expecting massive kind of sales cycles, but this is about going back to current relationships and saying, "Look, we have now increased capabilities. Here is the validation at a global level, and we believe we can deliver some of this performance to your business." It is about now going back and upselling and driving those current relationships forward, which we are hoping we will be able to accomplish in a bit of a shorter period of time.
Thank you, Alex. For my follow-up question, is it fair to assume, perhaps on the income statement piece of the equation here, but is it fair to assume after the Orion acquisition that margins are going to flip north of 50%? If so, how are you thinking about gross margins over time, Anthony?
Great question.
I think, look, we've been approaching 50% now. I think Orion has got a very similar profile. For us, we're going to continue to work through things as the business settles in with us and anticipate that margins will be very similar to what we have right now.
Okay. Thank you, guys. Talk soon.
Thank you.
The next question comes from Rob Goss with Ventum Financial. Please go ahead.
Thank you very much. Alex, you spoke about buy-in-Canada opportunities. Could you talk a bit more about buy-from-Canada or buy-from-New Zealand as opposed to someone else and how that may be in RFP stage or what sort of scale or scope that might be?
Yeah. Sure. Sure, Rob. I think there's quite a material amount of opportunity. And you may have also heard our Chairman, CEO of WELL Health Technologies, Hamid Shabazi, talk about a multi-kind of nine-figure opportunity en masse.
I'm not suggesting that we're going to capture that opportunity, but what I am suggesting is that we're in a really strong position with our partnership with WELL Health, with also the capabilities of some of our subsidiaries like Pentavere, Verisource, Cure Health, IntraHealth, and then, of course, Orion Health that will be in a very unique position to be applying and have a seat at the table with these RFPs and win some. That is our expectation, and we have some confidence around that.
As much as there is a movement to buy-in-Canada within Canada, are there other jurisdictions where buying, shall we say, non-U.S., is a very positive backwind for you?
Sure. Oh, sorry, Rob. Yeah, you did ask that. I misunderstood. Yes, there is.
There's kind of a sentiment that we're understanding and feeling throughout the Commonwealth where there could be—and this is a subjective comment—a preference for offerings within the Commonwealth for the Commonwealth. What's interesting is this is the jurisdiction where Orion Health has had some of its outsized success. As this kind of theme continues, Rob, we'll get back to you with some more precision.
Okay. Thank you very much.
Thank you, Rob.
The next question comes from Michael Seaman with Raymond James. Please go ahead.
Hey, Alex and Anthony. Congratulations on the quarter. Thanks for taking my question.
This is a similar question to Rob's, but I wonder if you could describe some of the opportunity you're seeing in the public sector to combine with the different business units within Healwell and then also with WELL and WELLstar to put together a proposal in response to RFPs that could compete directly with some of the big players that might still be in the running in these RFPs, like the Epic, Cerner, and IntraSystems of the world. Just describe how your combined capabilities compare to some of these large global healthcare softwares.
Michael, thank you very much for the question. This is an interesting topic because I think also for the WELL Health group of companies and by extension into Healwell and by extension again with Orion Health, we have a real strong spectrum of capabilities.
In fact, I think this is the first time where we're in a position where we can bid more broadly for some of the implementations that historically, perhaps, neither one of us separately would have been able to go after and win. Look, you're talking about some big players like the Epics and Cerners of the world, etc., where now it's not outlandish to be able to compare this whole ecosystem to be able to compete against those other incumbents. It's a really interesting time for the company. By the way, our capabilities are just going to continue to strengthen as we continue on this both organic and inorganic growth strategy.
Okay. Great. That's super helpful. Maybe I wonder if you could describe some of the geographies of focus for Healwell during maybe the next 12 and 24 months.
What are the areas that are most important to penetrate in the short and medium term?
Yeah. Thank you, Michael. Now, this is a great question. We spend a bit of time on this, obviously, strategically. Look, Orion Health has had tremendous momentum and has a tremendous reputation, number one in Canada and the extended Commonwealth. We are looking over the next 12-month period to focus efforts on growth in that region. On top of that, as I mentioned, what they have done in the Middle East is actually very, very special, having launched the world's largest health information exchange in Saudi Arabia, having deployed also very competently in Abu Dhabi and out in this region, they have developed an extremely strong reputation. We are looking at also a very exciting opportunity there.
As James Lee, my replacement, will attest, we're also exploring some compelling opportunity off the back of the success that Orion Health has had in the U.K. and Europe. Although that may sound broad, there are some tactical areas of focus, as I mentioned, where you'll see us demonstrate some success in the coming two quarters.
Thank you very much. Just one last probably broad question. In the press release describing the refreshed C-suite, there was a quote describing how Healwell's current opportunity set was larger than was originally anticipated. I'm curious, how has Healwell's view of its opportunity grown over the recent months as you're integrating for Orion?
I think, Michael, one thing we understood but perhaps underestimated is just how this theme here of integrating our AI capabilities into the Orion Health footprint, just how that can be actually practically and quickly executed against.
We feel that there is actually, outside of our previous expectations, a larger opportunity, and we're going to go after it. Stay tuned, and we'll come back and have some exciting news.
All right. Thank you very much. I'll pass it on now.
The next question comes from George Yurlybishev with Cloud Security. Please go ahead.
Hi, guys. Thanks for taking our questions and congrats on all the recent developments. The first question is for Anthony. It looks like your adjusted EBITDA this quarter was much stronger compared to your Q4 number. Should we view this as a sustainable run rate going forward, excluding the addition of Orion Health?
George, that's a great question. I think, look, our business, we saw some transitional things flow through this quarter, and maybe we ended up in a better spot than we expected.
I would say that we're safely going to be positive adjusted EBITDA for the full year, and maybe we'll leave it at that with Orion in the mix.
Okay. Got it. Got it. Thanks for that. Just on the macro side, with all the recent developments, how are you guys thinking about the potential impact of Trump's new drug pricing policy on your partnerships with pharma companies? Could this actually potentially be a positive for Healwell?
George, that's an interesting question, and I don't mean to kind of deflect, but that's something that we haven't quite internally started yet to kind of wrap our heads around. I think, look, where we're anchored is, number one, it's really to work and have our software support physicians and optimize patient care pathways. It's less on the focus, okay, what are the needs of life sciences?
If we can do that, if we can identify gaps in care or identify patients that are at high risk or that need interventions, then we're very confident by targeting and filling that value, we're going to grow commercially with our other enterprise customers.
That makes sense. Makes sense. Thanks, Alex. Just one more last question from you guys. More general question, I guess. Can you give us a sense of how you plan to balance and prioritize your organic revenue growth, additional M&A, and margin optimization in the near term?
Sure. George, I think what I shared and what we're trying to communicate, where a large part of management focus is in the coming quarters, is really on integration. We've gone through this high-growth phase. As I mentioned, one of the fastest-growing healthcare AI companies globally. Now we have the building blocks, and integration is key.
We want to demonstrate quarter by quarter that, number one, we can unlock more value through this integration. Number two, kind of set up the foundation for our next phase of growth, which is, of course, a big focus on organic growth. Also, as you have seen, M&A is part of our DNA. We are going to continue to look at opportunities from a capital allocation perspective.
Yeah. George, I mean to add, look, the next little while we will be focused again on integration and revenue synergies now that we have Orion in the mix with the global footprint that they have. We are going to be exploiting a lot of the organic capabilities in the near term. Having said that, to add to what Alex has said, we are constantly looking at outside opportunities that make sense.
Should they make sense, we'll definitely bring them into the mix. The focus, I would say, in the near term is on working with the products and the sales channels we have. Organic components is naturally just going to be where we're focusing in the near term right now.
Great. That's it from you guys. Thank you very much.
Thanks so much, George.
The next question comes from Gabriel Long with Beacon Securities. Please go ahead.
Good afternoon, and thanks for sending me in. Just a couple of questions. Anthony, first, just as a point of clarification, did any of the CAD 3 million in cost savings fall into the Q1 results, number one? And number two, as you go through the integration of Orion, do you suspect you'll get some more cost savings that might be over and above that CAD 3 million that you mentioned earlier?
It's a great question. The cost-saving efforts actually took place partway through Q1. So we did see, I would say, a half-quarter impact. I would say the majority of the CAD 3 million impact that I talk about is coming from the quarters two to four. There was a bit of an impact in Q1, but mostly will follow in the following quarters. In terms of Orion, I would say, look, we're really assessing things. They run a really, really tight shop, and we're very impressed with them. We don't have anything to call out at this stage. As time goes on, there's going to be some natural things we'll do to either bolster or adjust. At this stage, nothing to call out specifically as it relates to the Orion acquisition.
Gotcha. Thanks for that.
Just as a follow-up, Alex, during your investor update last week, you and I think James as well had talked about two proof of concepts you are running as part of the sort of the Orion and Healwell joint offering. I am just curious, with those proof of concepts, what sort of primary endpoints or milestones are the customers looking for to drive their decision to move forward with integrating Healwell into the existing Orion system?
Yeah. Thank you for the question. Largely, with some of these deployments, these platform deployments that Orion Health does, it allows for public sector customers to understand their data better, population level and also at the clinical level.
Where we're focused is we're adding some capabilities from both Pentavere and Cure Health that can help both manage data better, search data better, and also be able to screen that data from a risk stratification perspective. That is the kind of theme that you'll see us demonstrate. As we mentioned, there's some active work that we've already started and is underway.
That's perfect. Thanks for that, and congrats on the progress.
Thank you so much, Gabe.
This concludes the question and answer session. I would like to turn the conference back over to Dr. Alexander Dobranowski for any closing remarks. Please go ahead.
Thank you. In closing, I want to thank everyone once again for joining our call. Thank you to the analysts for their questions. We look forward to providing more updates in the future. Thanks very much.
This brings to a close today's conference call. You may disconnect your lines. Thank you for participating, and have a pleasant day.