Ono Pharmaceutical Co., Ltd. (TYO:4528)

Japan flag Japan · Delayed Price · Currency is JPY
2,214.50
+11.50 (0.52%)
Dec 16, 2025, 2:25 PM JST
31.74%
Market Cap1.04T
Revenue (ttm)503.67B
Net Income (ttm)48.50B
Shares Out469.91M
EPS (ttm)103.10
PE Ratio21.37
Forward PE14.84
Dividend80.00 (3.67%)
Ex-Dividend DateMar 30, 2026
Volume880,500
Average Volume2,082,730
Open2,220.00
Previous Close2,203.00
Day's Range2,206.00 - 2,229.00
52-Week Range1,474.00 - 2,237.00
Beta-0.02
RSI67.73
Earnings DateFeb 2, 2026

About Ono Pharmaceutical

Ono Pharmaceutical Co., Ltd. produces, purchases, and sells pharmaceuticals and diagnostic reagents worldwide. It offers Opdivo intravenous infusion and Kyprolis intravenous injection for malignant tumors; Emend capsule intravenous injections for chemotherapy-induced nausea and vomiting; Demser capsules for the symptoms in patients with pheochromocytoma; Mektovi, Velexbru, and Braftovi capsules for malignant tumors; and ADLUMIZ tablets for cancer cachexia. The company also provides Glactiv tablets for type 2 diabetes; Forxiga tablets for diabet... [Read more]

Sector Healthcare
Founded 1717
Employees 4,287
Stock Exchange Tokyo Stock Exchange
Ticker Symbol 4528
Full Company Profile

Financial Performance

In 2024, Ono Pharmaceutical's revenue was 486.87 billion, a decrease of -3.14% compared to the previous year's 502.67 billion. Earnings were 50.05 billion, a decrease of -60.89%.

Financial Statements

News

Deciphera Announces Oral Presentation of Positive Topline Results from Phase 2a Study of Sapablursen in Polycythemia Vera at the 67th American Society of Hematology (ASH) Annual Meeting

OSAKA, Japan & WALTHAM, Mass.--(BUSINESS WIRE)--Deciphera Pharmaceuticals, a member of Ono Pharmaceutical Co., Ltd. (Headquarters: Osaka, Japan; President and COO: Toichi Takino; “Ono”), today announc...

9 days ago - Business Wire

Deciphera Announces the Opening of a New Office in Zug, Switzerland

OSAKA, Japan & WALTHAM, Mass.--(BUSINESS WIRE)--Ono Pharmaceutical Co., Ltd. (Headquarters: Osaka, Japan; President and COO: Toichi Takino; “Ono”), today announced the opening of a new 733-square-mete...

4 weeks ago - Business Wire

Deciphera Announces Multiple Data Presentations at the Connective Tissue Oncology Society (CTOS) Annual Meeting 2025

OSAKA, Japan & WALTHAM, Mass.--(BUSINESS WIRE)--Ono Pharmaceutical Co., Ltd. (Headquarters: Osaka, Japan; President and COO: Toichi Takino; “Ono”), today announced that data from multiple pipeline pro...

4 weeks ago - Business Wire

Ono Pharmaceutical reports Q2 results

6 weeks ago - Seeking Alpha

Deciphera Presents 2-Year Efficacy and Safety Results from MOTION Phase 3 Study of ROMVIMZA™ (vimseltinib) in Patients with Tenosynovial Giant Cell Tumor (TGCT) at the European Society for Medical Oncology Congress 2025

OSAKA, Japan & WALTHAM, Mass.--(BUSINESS WIRE)--Ono Pharmaceutical Co., Ltd. (Headquarters: Osaka, Japan; President and COO: Toichi Takino; “Ono”), today announced the two-year efficacy and safety res...

2 months ago - Business Wire

Ono Announces Encouraging Efficacy Signals of ONO-2808, a S1P5 Receptor Agonist, in an interim analysis of Ongoing Phase 2 Clinical Trial in Patients with Multiple System Atrophy

Efficacy signals were observed in an interim analysis of a Phase 2 clinical trial for ONO-2808, a S1P5 receptor agonist Phase 2 clinical trial was conducted in early multiple system atrophy patients w...

2 months ago - Benzinga

Deciphera Receives European Commission Approval of ROMVIMZA™ (vimseltinib) for the Treatment of Tenosynovial Giant Cell Tumor (TGCT)

OSAKA, Japan & WALTHAM, Mass.--(BUSINESS WIRE)--Ono Pharmaceutical Co., Ltd. (Headquarters: Osaka, Japan; President and COO: Toichi Takino; “Ono”), today announced that the European Commission (EC) ha...

3 months ago - Business Wire

Deciphera Announces Positive CHMP Opinion for ROMVIMZA™ (vimseltinib) for the Treatment of Tenosynovial Giant Cell Tumor (TGCT)

OSAKA, Japan & WALTHAM, Mass.--(BUSINESS WIRE)--Deciphera Pharmaceuticals, LLC, a biopharmaceutical company focused on discovering, developing, and commercializing important new medicines, and Ono Pha...

5 months ago - Business Wire

Ono Pharmaceutical and Vertex Announce Strategic Agreement to Develop and Commercialize Povetacicept in Japan and South Korea

Ono and Vertex have entered into an exclusive collaboration and license agreement for povetacicept in Japan and South Korea Povetacicept is a therapeutic in development for multiple serious B cell-med...

6 months ago - Benzinga

Ono Pharmaceutical and Vertex Announce Strategic Agreement to Develop and Commercialize Povetacicept in Japan and South Korea

OSAKA, Japan & BOSTON--(BUSINESS WIRE)--Ono Pharmaceutical Co., Ltd. (Headquarters: Osaka, Japan; President and COO: Toichi Takino; “Ono”) and Vertex Pharmaceuticals Incorporated (Headquarters: Boston...

6 months ago - Business Wire

Ono Pharmaceutical reports FY results

7 months ago - Seeking Alpha

What's Going On With Cue Biopharma Shares Tuesday?

Cue Biopharma, Inc. (NASDAQ: CUE) shares are trading lower on Tuesday. The company reported 2024 fiscal-year earnings on Monday after the market closed. What To Know: The company reported collaborati...

9 months ago - Benzinga

Ionis Pharmaceuticals Partners With Japan-Based Ono Pharmaceutical For Rare Blood Disease Drug In Over $800 Million Deal

On Tuesday, Ionis Pharmaceuticals Inc (NASDAQ: IONS) and Ono Pharmaceutical Co., Ltd entered into a license agreement in which Ono obtains exclusive global rights for the development and commercializ...

9 months ago - Benzinga

Ionis out licenses blood disorder therapy to Ono in a deal worth up to $940M

Ionis Pharmaceuticals (NASDAQ:IONS) stock in focus as the company inks a $940M deal with Ono Pharmaceutical (OPHLY) to license a blood disorder drug. Read more here.

9 months ago - Seeking Alpha

U.S. FDA Grants Full Approval of Deciphera's ROMVIMZA™ (vimseltinib) for the Treatment of Symptomatic Tenosynovial Giant Cell Tumor (TGCT)

In the MOTION Phase 3 study, ROMVIMZA met primary endpoint of improved objective response rate (ORR) compared to placebo and all key secondary endpoints with statistically significant and clinically m...

10 months ago - Benzinga

U.S. FDA Grants Full Approval of Deciphera's ROMVIMZA™ (vimseltinib) for the Treatment of Symptomatic Tenosynovial Giant Cell Tumor (TGCT)

OSAKA, Japan & WALTHAM, Mass.--(BUSINESS WIRE)--Ono Pharmaceutical Co., Ltd. (Headquarters: Osaka, Japan; President: Toichi Takino; “Ono”) announced that the U.S. Food and Drug Administration (FDA) ha...

10 months ago - Business Wire

Ono Pharmaceutical reports Q2 results

1 year ago - Seeking Alpha

Equillium says Ono not acquiring itolizumab, stock craters 36%

Equillium (EQ) stock cratered 36% after the company said it was pausing certain programs due to Ono Pharmaceutical failing to exercise an option to acquire its drug itolizumab.

1 year ago - Seeking Alpha

Kinaxis to Bolster Supply Chain Operations of Ono Pharmaceutical

Kinaxis provides end-to-end supply chain orchestration platform to support Ono Pharmaceutical’s further global growth OTTAWA, Ontario — Kinaxis® Inc. (TSX:KXS), a global leader in end-to-end supply ch...

1 year ago - Financial Post

Kinaxis to Bolster Supply Chain Operations of Ono Pharmaceutical

OTTAWA, Ontario--(BUSINESS WIRE)--Kinaxis® Inc. (TSX:KXS), a global leader in end-to-end supply chain orchestration, today announced Ono Pharmaceutical Co., Ltd.'s adoption of Kinaxis to help orchestr...

1 year ago - Business Wire