OPKO Health, Inc. (OPK)

NASDAQ: OPK · Real-Time Price · USD
1.130
+0.030 (2.73%)
May 18, 2026, 4:00 PM EDT - Market closed
Market Cap853.25M -20.3%
Revenue (ttm)581.12M -15.7%
Net Income-212.92M
EPS-0.28
Shares Out 755.09M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume2,581,417
Open1.090
Previous Close1.100
Day's Range1.090 - 1.145
52-Week Range0.977 - 1.600
Beta1.41
AnalystsBuy
Price Target3.76 (+232.74%)
Earnings DateApr 28, 2026

About OPK

OPKO Health, Inc. operates as a healthcare company, in the United States, Ireland, Chile, Spain, Israel, Mexico, and internationally. The company operates in two segments, Pharmaceutical and Diagnostics. The Pharmaceutical segment develops MDX2001, a tetra-specific antibody targeting several types of solid tumors in Phase 1 clinical trials; MDX2003, a tetra-specific antibody targeting two antigens for hematological tumors in Phase 1 clinical trials; and MDX2004, a trispecific immune modulator to rebuild and sustain the patient's own immune syst... [Read more]

Sector Healthcare
IPO Date Nov 2, 1995
Employees 2,275
Stock Exchange NASDAQ
Ticker Symbol OPK
Full Company Profile

Financial Performance

In 2025, OPKO Health's revenue was $606.88 million, a decrease of -14.90% compared to the previous year's $713.14 million. Losses were -$225.68 million, 324.0% more than in 2024.

Financial Statements

Analyst Summary

According to 7 analysts, the average rating for OPK stock is "Buy." The 12-month stock price target is $3.76, which is an increase of 232.74% from the latest price.

Price Target
$3.76
(232.74% upside)
Analyst Consensus: Buy
Stock Forecasts

News

OPKO Health Proxy statement: Proxy filing

OPKO Health filed a proxy statement on May 15, 2026, providing details for shareholder voting and corporate governance matters.

3 days ago - Filings

OPKO Health's ModeX Therapeutics Will Present Data Demonstrating In Vivo CAR-T Cell Generation and Deep B-Cell Depletion in Preclinical Studies

Multispecific antibody conjugated LNP/mRNA platform enables in vivo T-cell engineering and systemic B-cell depletion in animal models  Data will be presented at the American Society of Gene & Cell The...

6 days ago - GlobeNewsWire

OPKO Health Slides: Corporate presentation

OPKO Health has posted slides in relation to its latest quarterly earnings report, which was published on May 8, 2026.

10 days ago - Filings

OPKO Health Expands Nicoya Agreement to Support RAYALDEE® Commercialization in Greater China

MIAMI, April 30, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) (OPKO) today announced that its subsidiary EirGen Pharma Limited (EirGen) has entered into an amendment to its agreement with ...

18 days ago - GlobeNewsWire

BioReference® Launches BioReference Direct™, Expanding Access to Consumer-Initiated Diagnostic Testing Through a Fully Integrated Digital Platform

ELMWOOD PARK, N.J., April 30, 2026 (GLOBE NEWSWIRE) -- BioReference® Health LLC, an OPKO Health, Inc. company and a trusted provider of diagnostic testing in the United States, today announced the lau...

18 days ago - GlobeNewsWire

OPKO Health Proxy statement: Proxy filing

OPKO Health filed a proxy statement on April 30, 2026, providing details for shareholder voting and corporate governance matters.

18 days ago - Filings

OPKO Health Proxy statement: Proxy filing

OPKO Health filed a proxy statement on April 30, 2026, providing details for shareholder voting and corporate governance matters.

18 days ago - Filings

Opko Health downgraded to Market Perform from Outperform at Barrington

Barrington analyst Michael Petusky downgraded Opko Health (OPK) to Market Perform from Outperform with no price target The firm previously had expected BRH break-even or profitability in 2026 and now…

19 days ago - TheFly

OPKO Health Earnings Call Transcript: Q1 2026

Q1 2026 saw progress in clinical pipeline, improved operating losses, and strong cash reserves. Diagnostics and pharma segments showed sequential and year-over-year improvements, with guidance reaffirmed for 2026. Partnerships and streamlined operations support future growth.

20 days ago - Transcripts

OPKO Health Earnings release: Q1 2026

OPKO Health released its Q1 2026 earnings on April 28, 2026, summarizing the period's financial results.

20 days ago - Filings

OPKO Health Quarterly report: Q1 2026

OPKO Health has published its Q1 2026 quarterly earnings report on April 28, 2026.

20 days ago - Filings

OPKO Health Reports First Quarter 2026 Business Highlights and Financial Results

MIAMI, April 28, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) (OPKO) reports business highlights and financial results for the three months ended March 31, 2026. Highlights from the first ...

20 days ago - GlobeNewsWire

OPKO Health's ModeX Therapeutics Begins Clinical Trial of Tetraspecific Antibody for Treatment of B-cell Lymphomas

Patients dosed in Phase 1 safety and tolerability study of MDX2003, a novel T-cell engager designed to optimize killing of lymphomas

26 days ago - GlobeNewsWire

OPKO Health to Report First Quarter 2026 Financial Results on April 28, 2026

MIAMI, April 21, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) plans to report operating and financial results for the three months ended March 31, 2026 after the close of the U.S. financia...

27 days ago - GlobeNewsWire

Opko Health price target lowered to $1.50 from $2.25 at Barrington

Barrington lowered the firm’s price target on Opko Health (OPK) to $1.50 from $2.25 and keeps an Outperform rating on the shares. The company reported a better than expected Q4…

2 months ago - TheFly

OPKO Health to Participate in the Jefferies Biotech on the Beach Summit

MIAMI, Feb. 27, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (Nasdaq: OPK) announced today that management will be participating in the Jefferies Biotech on the Beach Summit, being held March 10-11, 202...

2 months ago - GlobeNewsWire

OPKO Health Earnings Call Transcript: Q4 2025

Q4 2025 revenue declined year-over-year due to asset sales, but diagnostics and pharma segments showed operational improvements, with 4Kscore and international sales driving growth. Strong cash position supports R&D and accelerated share repurchases.

2 months ago - Transcripts

OPKO Health Annual report: Q4 2025

OPKO Health has published its Q4 2025 annual report on February 26, 2026.

2 months ago - Filings

OPKO Health Earnings release: Q4 2025

OPKO Health released its Q4 2025 earnings on February 26, 2026, summarizing the period's financial results.

2 months ago - Filings

OPKO Health Reports Fourth Quarter 2025 Business Highlights and Financial Results

MIAMI, Feb. 26, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) (OPKO) reports business highlights and financial results for the three and 12 months ended December 31, 2025, and introduces fi...

2 months ago - GlobeNewsWire

OPKO Health to Report Fourth Quarter 2025 Financial Results on February 26

MIAMI, Feb. 12, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (NASDAQ: OPK) plans to report operating and financial results for the three and 12 months ended December 31, 2025, after the close of the U.S...

3 months ago - GlobeNewsWire

Opko Health Entera Bio, Entera Bio expand partnership to advance PTH tablet

OPKO Health (OPK), through its wholly owned subsidiary, OPKO Biologics, and Entera Bio (ENTX), announced the expansion of their 2025 Collaboration and License Agreement to advance the first oral long-...

Other symbols: ENTX
3 months ago - TheFly

OPKO Health and Entera Bio Expand Partnership to Advance First-in-Class Oral Long Acting PTH Tablet for Patients with Hypoparathyroidism

This is the third  program that s uccessfully combine s Entera's oral peptide N- Tab ® platform with OPKO 's advanced protein chemistry capabilities

3 months ago - GlobeNewsWire

OPKO Health Transcript: 44th Annual J.P. Morgan Healthcare Conference

The company has restructured to focus on therapeutics, divesting diagnostics for profitability and advancing a robust pipeline through partnerships with Merck, Regeneron, and BARDA. Key assets include a Merck-partnered EBV vaccine, multi-specific antibodies, and a growing diagnostics business centered on the 4Kscore test.

4 months ago - Transcripts

OPKO Health to Participate in the 44th Annual J.P. Morgan Healthcare Conference

MIAMI, Jan. 06, 2026 (GLOBE NEWSWIRE) -- OPKO Health, Inc. (Nasdaq: OPK) announced today that management will be participating in the 44th Annual J.P. Morgan Healthcare Conference, being held January...

4 months ago - GlobeNewsWire