Rhythm Pharmaceuticals, Inc. (RYTM)
| Market Cap | 7.25B +29.0% |
| Revenue (ttm) | 239.92M +53.5% |
| Net Income | -210.22M |
| EPS | -3.12 |
| Shares Out | 68.53M |
| PE Ratio | n/a |
| Forward PE | n/a |
| Dividend | n/a |
| Ex-Dividend Date | n/a |
| Volume | 1,453,193 |
| Open | 100.25 |
| Previous Close | 102.78 |
| Day's Range | 98.77 - 108.51 |
| 52-Week Range | 74.50 - 122.20 |
| Beta | 1.97 |
| Analysts | Strong Buy |
| Price Target | 139.73 (+32.1%) |
| Earnings Date | Aug 4, 2026 |
About RYTM
Rhythm Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the rare neuroendocrine diseases in the United States and internationally. The company’s lead product candidate is IMCIVREE (setmelanotide), a rare melanocortin-4 receptor for the treatment of pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1, leptin receptor (LEPR) deficiency obesity, Bardet-Biedl and Alström syndrome, Prader-Willi syndrome, and hypothalamic obesity. It is in Phase 3 clinical trials for treating acquired hypothalamic... [Read more]
Financial Performance
In 2025, Rhythm Pharmaceuticals's revenue was $189.76 million, an increase of 45.83% compared to the previous year's $130.13 million. Losses were -$201.92 million, -23.68% less than in 2024.
Financial StatementsAnalyst Summary
According to 16 analysts, the average rating for RYTM stock is "Strong Buy." The 12-month stock price target is $139.73, which is an increase of 32.10% from the latest price.
News
Rhythm Pharma's obesity drug shows promise for brain tumor-related weight condition
Rhythm Pharmaceuticals said on Tuesday its experimental weekly injectable drug helped reduce body weight in patients with a rare form of obesity caused by damage to the brain, according to prelimina...
Rhythm Pharmaceuticals Earnings Call Transcript: Q2 2026
IMCIVREE’s U.S. launch for acquired hypothalamic obesity saw strong early demand and broad prescriber engagement, driving 19% sequential revenue growth in Q2 2026. Positive clinical data for next-generation MC4R agonists and ongoing international expansion support a durable growth outlook.
Rhythm Pharmaceuticals Earnings release: Q2 2026
Rhythm Pharmaceuticals released its Q2 2026 earnings on August 4, 2026, summarizing the period's financial results.
Rhythm Pharmaceuticals Slides: Q2 2026
Rhythm Pharmaceuticals has posted slides in relation to its Q2 2026 quarterly earnings report, which was published on August 4, 2026.
Rhythm Pharmaceuticals’ RM-718 shows efficacy in Phase 2 obesity trial
Rhythm Pharmaceuticals (RYTM) announced preliminary results from the ongoing Phase 2 trial evaluating RM-718, Rhythm’s investigational once-weekly MC4R agonist, in patients with acquired hypothalamic ...
Rhythm Pharmaceuticals Reports Second Quarter 2026 Financial Results and Business Update
-- U.S. launch of IMCIVREE ® (setmelanotide) for acquired hypothalamic obesity (HO) starts strong with more than 400 patient start forms since FDA approval as of June 30, 2026 -- -- Second quarter 202...
Rhythm Pharmaceuticals Announces Preliminary Data from Phase 2 Trial that Showed RM-718 Demonstrated Positive Efficacy Signal in Acquired Hypothalamic Obesity
-- -11.6% mean reduction in BMI from baseline at Week 16 (n=7) -- -- BMI reductions consistent with setmelanotide and bivamelagon --
Rhythm Pharmaceuticals initiated with an Overweight at JPMorgan
JPMorgan analyst Priyanka Grover initiated coverage of Rhythm Pharmaceuticals (RYTM) with an Overweight rating and $145 price target The firm likes Rhythm’s opportunity to grow Imcivree from a rare ge...
Rhythm Pharmaceuticals to Report Second Quarter 2026 Financial Results on Tuesday, August 4, 2026
BOSTON, July 21, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rar...
Rhythm Pharmaceuticals Announces The New England Journal of Medicine Publication of Phase 3 TRANSCEND Trial Results in Acquired Hypothalamic Obesity
BOSTON, July 08, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rar...
Rhythm Pharmaceuticals price target raised to $141 from $137 at RBC Capital
RBC Capital raised the firm’s price target on Rhythm Pharmaceuticals (RYTM) to $141 from $137 and keeps an Outperform rating on the shares as part of a broader research note…
Rhythm Pharmaceuticals price target raised to $151 from $143 at Canaccord
Canaccord analyst Whitney Ijem raised the firm’s price target on Rhythm Pharmaceuticals (RYTM) to $151 from $143 and keeps a Buy rating on the shares. The firm updated its model…
Rhythm Pharmaceuticals Announces Multiple New Data Presentations from MC4R Agonists in Acquired Hypothalamic Obesity (HO), Bardet-Biedl Syndrome (BBS) and Prader-Willi Syndrome (PWS) at ENDO 2026
BOSTON, June 15, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rar...
Rhythm Pharmaceuticals price target raised to $155 from $144 at Wells Fargo
Wells Fargo raised the firm’s price target on Rhythm Pharmaceuticals (RYTM) to $155 from $144 and keeps an Overweight rating on the shares. IMCIVREE’s six-month Prader-Willi syndrome update further de...
Rhythm announces preliminary data from Phase 2 trial of setmelanotide
Rhythm Pharmaceuticals (RYTM) announced preliminary data from a Phase 2 trial evaluating setmelanotide in patients with Prader-Willi syndrome delivered during the Endocrine Society’s Annual Meeting in...
Rhythm Pharmaceuticals Transcript: Study result
Interim phase II results in severe Prader-Willi syndrome show setmelanotide led to consistent reductions in BMI, fat mass, hyperphagia, and anxiety, with notable behavioral and quality of life improvements. The drug was well-tolerated, and all patients remained in the trial at six months.
Rhythm Pharmaceuticals Slides: Study result
Rhythm Pharmaceuticals has posted slides in relation to its latest quarterly earnings report, which was published on June 13, 2026.
Rhythm Pharmaceuticals Press release: Study result
Rhythm Pharmaceuticals issued a press release on June 13, 2026, disclosing material business information to investors.
Rhythm Pharmaceuticals Presents Positive Interim Six-month Data from Phase 2 Trial of Setmelanotide in Patients with Prader-Willi Syndrome (PWS) at ENDO 2026
-- Patients with PWS treated with setmelanotide therapy (N=17) achieved clinically meaningful BMI or BMI z-score reductions, reductions in fat mass with preservation of lean mass, and improvements in ...
Rhythm Pharmaceuticals to Announce Interim Six-Month Phase 2 Results Evaluating Setmelanotide in Patients with Prader-Willi Syndrome
BOSTON, June 12, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rar...
Rhythm Pharmaceuticals Transcript: Goldman Sachs 47th Annual Global Healthcare Conference 2026
Six-month data for Praloretel and updated RM-718 results will be presented at ENDO, while IMCIVREE's HO launch targets a 10,000-patient U.S. market with strong physician interest and high anticipated adherence. The pipeline includes both oral and injectable options, with a focus on rare diseases and a solid cash position for ongoing development.
Rhythm Pharmaceuticals Transcript: Jefferies Global Healthcare Conference 2026
IMCIVREE's U.S. HO launch shows strong early uptake and broad physician engagement, with international expansion and new clinical data on the horizon. Next-generation therapies are advancing, and market opportunities are expected to grow as diagnosis and awareness increase.
Rhythm Pharmaceuticals Announces Seven Abstracts Accepted for Presentation at ENDO 2026
BOSTON, May 29, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare...
Rhythm Pharmaceuticals Proxy statement: Proxy filing
Rhythm Pharmaceuticals filed a proxy statement on May 29, 2026, providing details for shareholder voting and corporate governance matters.
Rhythm Pharmaceuticals Announces Publication of New Bardet-Biedl Syndrome Diagnostic Algorithm in the American Journal of Medical Genetics
BOSTON, May 28, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare...