Rhythm Pharmaceuticals, Inc. (RYTM)

NASDAQ: RYTM · Real-Time Price · USD
88.38
+0.72 (0.82%)
At close: Jun 12, 2026, 4:00 PM EDT
89.87
+1.49 (1.69%)
After-hours: Jun 12, 2026, 7:58 PM EDT
Market Cap6.06B +53.8%
Revenue (ttm)217.17M +58.7%
Net Income-207.84M
EPS-3.14
Shares Out 68.53M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume554,372
Open87.65
Previous Close87.66
Day's Range87.65 - 90.16
52-Week Range60.70 - 122.20
Beta1.92
AnalystsStrong Buy
Price Target138.20 (+56.37%)
Earnings DateMay 5, 2026

About RYTM

Rhythm Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the rare neuroendocrine diseases in the United States and internationally. The company’s lead product candidate is IMCIVREE (setmelanotide), a rare melanocortin-4 receptor for the treatment of pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1, leptin receptor (LEPR) deficiency obesity, Bardet-Biedl and Alström syndrome, Prader-Willi syndrome, and hypothalamic obesity. It is in Phase 3 clinical trials for treating acquired hypothalamic... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Oct 5, 2017
Employees 414
Stock Exchange NASDAQ
Ticker Symbol RYTM
Full Company Profile

Financial Performance

In 2025, Rhythm Pharmaceuticals's revenue was $189.76 million, an increase of 45.83% compared to the previous year's $130.13 million. Losses were -$201.92 million, -23.68% less than in 2024.

Financial Statements

Analyst Summary

According to 16 analysts, the average rating for RYTM stock is "Strong Buy." The 12-month stock price target is $138.2, which is an increase of 56.37% from the latest price.

Price Target
$138.2
(56.37% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Rhythm Pharmaceuticals Presents Positive Interim Six-month Data from Phase 2 Trial of Setmelanotide in Patients with Prader-Willi Syndrome (PWS) at ENDO 2026

-- Patients with PWS treated with setmelanotide therapy (N=17) achieved clinically meaningful BMI or BMI z-score reductions, reductions in fat mass with preservation of lean mass, and improvements in ...

Other symbols: PWS
1 day ago - GlobeNewsWire

Rhythm Pharmaceuticals to Announce Interim Six-Month Phase 2 Results Evaluating Setmelanotide in Patients with Prader-Willi Syndrome

BOSTON, June 12, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rar...

Other symbols: PWS
1 day ago - GlobeNewsWire

Rhythm Pharmaceuticals Transcript: Goldman Sachs 47th Annual Global Healthcare Conference 2026

Six-month data for Praloretel and updated RM-718 results will be presented at ENDO, while IMCIVREE's HO launch targets a 10,000-patient U.S. market with strong physician interest and high anticipated adherence. The pipeline includes both oral and injectable options, with a focus on rare diseases and a solid cash position for ongoing development.

5 days ago - Transcripts

Rhythm Pharmaceuticals Transcript: Jefferies Global Healthcare Conference 2026

IMCIVREE's U.S. HO launch shows strong early uptake and broad physician engagement, with international expansion and new clinical data on the horizon. Next-generation therapies are advancing, and market opportunities are expected to grow as diagnosis and awareness increase.

9 days ago - Transcripts

Rhythm Pharmaceuticals Announces Seven Abstracts Accepted for Presentation at ENDO 2026

BOSTON, May 29, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare...

16 days ago - GlobeNewsWire

Rhythm Pharmaceuticals Proxy statement: Proxy filing

Rhythm Pharmaceuticals filed a proxy statement on May 29, 2026, providing details for shareholder voting and corporate governance matters.

16 days ago - Filings

Rhythm Pharmaceuticals Announces Publication of New Bardet-Biedl Syndrome Diagnostic Algorithm in the American Journal of Medical Genetics

BOSTON, May 28, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare...

17 days ago - GlobeNewsWire

Rhythm Pharmaceuticals Announces Participation in Upcoming Investor Conferences

BOSTON, May 26, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare...

19 days ago - GlobeNewsWire

Rhythm Pharmaceuticals Slides: Corporate presentation

Rhythm Pharmaceuticals has posted slides in relation to its latest quarterly earnings report, which was published on May 26, 2026.

19 days ago - Filings

Rhythm Pharmaceuticals Transcript: Bank of America Global Healthcare Conference 2026

The company’s drug targets rare genetic and acquired obesity syndromes, with a recent HO launch showing strong early uptake and broad physician engagement. Next-generation therapies aim to improve convenience and reduce side effects, while ongoing studies in Prader-Willi syndrome may expand indications.

4 weeks ago - Transcripts

Rhythm Pharmaceuticals Announces New Data Presentations at the 2026 European Congress of Endocrinology

– Real world data showed clinically meaningful BMI reductions with setmelanotide in 62 adults with 12-month data living with acquired hypothalamic obesity (HO) in France –

4 weeks ago - GlobeNewsWire

Rhythm Pharmaceuticals price target raised to $143 from $140 at Canaccord

Canaccord raised the firm’s price target on Rhythm Pharmaceuticals (RYTM) to $143 from $140 and keeps a Buy rating on the shares. The firm said the company delivered a topline…

5 weeks ago - TheFly

Rhythm Pharmaceuticals Announces Participation in Upcoming Bank of America Global Healthcare Conference

BOSTON, May 06, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (Nasdaq: RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare...

5 weeks ago - GlobeNewsWire

Rhythm Pharmaceuticals Earnings Call Transcript: Q1 2026

Q1 2026 saw $60.1M in revenue, driven by BBS and a strong U.S. launch of IMCIVREE for acquired HO, with over 150 start forms and positive payer response. International expansion advanced with EU approval and Japan NDA filing, supporting a robust outlook for 2026.

5 weeks ago - Transcripts

Rhythm Pharmaceuticals Earnings release: Q1 2026

Rhythm Pharmaceuticals released its Q1 2026 earnings on May 5, 2026, summarizing the period's financial results.

5 weeks ago - Filings

Rhythm Pharmaceuticals Slides: Q1 2026

Rhythm Pharmaceuticals has posted slides in relation to its Q1 2026 quarterly earnings report, which was published on May 5, 2026.

5 weeks ago - Filings

Rhythm Pharmaceuticals Quarterly report: Q1 2026

Rhythm Pharmaceuticals has published its Q1 2026 quarterly earnings report on May 5, 2026.

5 weeks ago - Filings

Rhythm Pharmaceuticals Proxy statement: Proxy filing

Rhythm Pharmaceuticals filed a proxy statement on May 5, 2026, providing details for shareholder voting and corporate governance matters.

5 weeks ago - Filings

Rhythm Pharmaceuticals reports Q1 EPS (83c), consensus (86c)

Reports Q1 revenue $60.11M, consensus $56.07M. “The U.S and European approvals of IMCIVREE mark a transformational milestone for patients with acquired hypothalamic obesity who, until now, had no appr...

5 weeks ago - TheFly

Rhythm Pharmaceuticals sees FY26 operating expenses $385M-$415M

Meeker added, “In addition, we continue to advance our MC4R agonism pipeline with upcoming data readouts from ongoing trials of setmelanotide in Prader-Willi syndrome and our weekly injectable, RM-718...

5 weeks ago - TheFly

Rhythm Pharmaceuticals Reports First Quarter 2026 Financial Results and Business Update

-- IMCIVREE ® (setmelanotide) launched in the U.S. for acquired hypothalamic obesity; more than 150 patient start forms received in the first six weeks following FDA approval on March 19, 2026 -- -- F...

5 weeks ago - GlobeNewsWire

Rhythm Pharmaceuticals presents Phase 3 TRANSCEND trial data

Rhythm Pharmaceuticals (RYTM) announced the presentation of new data delivered by Rhythm and its partners at The Pediatric Endocrine Society Annual Meeting. “The data presented provide important longe...

5 weeks ago - TheFly

Rhythm Pharmaceuticals Announces New Data Presentations in Acquired Hypothalamic Obesity at Pediatric Endocrine Society

-- Pediatric patients (n=10) with acquired hypothalamic obesity achieved sustained reductions in BMI and BMI-Z at 2.5 years of setmelanotide therapy -- -- Weight category improvements observed in pedi...

5 weeks ago - GlobeNewsWire

Rhythm Pharmaceuticals’ Imcivree granted MAA in Europe for obesity

Rhythm Pharmaceuticals (RYTM) announced the European Commission, or EC, has expanded the marketing authorization for Imcivree – setmelanotide – to include the treatment of obesity and control of hunge...

6 weeks ago - TheFly

Rhythm Pharmaceuticals Announces IMCIVREE® (Setmelanotide) Granted Marketing Authorization by European Commission for the Treatment of Obesity and Control of Hunger in Patients with Acquired Hypothalamic Obesity

-- First therapy to be FDA-approved and EC-authorized for acquired hypothalamic obesity -- -- European Commission grants authorization in adults and children 4 years of age and above with acquired hyp...

6 weeks ago - GlobeNewsWire