Good afternoon, and welcome to the Agilent Technologies fourth quarter earnings conference call. All lines have been placed on mute to prevent any background noise. After the speakers' remarks, there will be a question and answer session. If you would like to ask a question during this time, simply press star followed by the number 1 on your telephone keypad. If you would like to withdraw your question, press the pound key. Thank you. I'd like to introduce you to the host for today's conference, Ankur Dhingra, Vice President of Investor Relations. Sir, please go ahead.
Thank you. Welcome everyone to Agilent's fourth quarter and full year conference call for fiscal year 2020. With me are Mike McMullen, Agilent's President and CEO. Bob McMahon, Agilent's Senior Vice President and CFO. Joining in the Q&A after Bob's comments will be Jacob Thaysen, President of Agilent's Life Sciences and Applied Markets Group, Sam Raha, President of Agilent's Diagnostics and Genomics Group. Padraig McDonnell, President of Agilent CrossLab Group. This presentation is being webcast live. The news release, investor presentation, and information to supplement today's discussion, along with a recording of this webcast, are made available on our website at investor.agilent.com. Today's comments by Mike and Bob will refer to non-GAAP financial measures. You will find the most directly comparable GAAP financial metrics and reconciliations on our website.
Unless otherwise noted, all references to increases or decreases in financial metrics are year-over-year, and references to revenue growth are on a core basis. Core revenue growth excludes the impact of currency and the acquisitions and divestitures completed within the past 12 months. Guidance is based on exchange rates as of October 31st, 2020. We will also make forward-looking statements about the financial performance of the company. These statements are subject to risks and uncertainties and are only valid as of today. The company assumes no obligation to update them. Please look at the company's recent SEC filings for a more complete picture of our risks and other factors. Also, as announced, we will hold our virtual Investor Day in a few weeks on December ninth. The event will include presentations from our CEO, CFO, and the three group presidents, followed by a Q&A.
We look forward to having you join us on December ninth. Now I would like to turn the call over to Mike.
Thanks, Ankur, thanks to everyone for joining us on our call today. Today, I want to get straight to our quarterly results because they tell a very compelling story. The Agilent team delivered a very strong close to 2020. We posted revenues of $1.48 billion during the quarter. Revenues are up 8% on a reported basis and up 6% core. Operating margins are a healthy 24.9%. EPS of $0.98 is up 10% year-over-year. These numbers tell the story of a strong, resilient company that is built for continued growth. Our better-than-expected results are due to the strength of our core business, along with signs of recovery in our end markets. Geographically, China continues to lead the way with double-digit growth. From an end market view, both our pharmaceutical and food businesses grew double digits.
In addition, our Chemical and Energy business grew after two quarters of declines, exceeding our expectations. We also saw a rebound in U.S. sales during the quarter. Overall, COVID-19 tailwinds contributed just over two points of core growth. Achieving these results in the face of a global pandemic is a tribute to our team and the company we've built over the last five years. I couldn't be more pleased with the way the Agilent team has performed over the last quarter and throughout 2020. They have again proven their ability to work together and step up to meet any challenge that comes their way. During the quarter, all three of our business groups grew high single digits on a reported basis. Our Life Science and Applied Markets Group generated $671 million in revenue, up 8% on a reported basis and up 4% core. LSAG growth is broad-based.
The Cell Analysis and Mass Spec businesses both grew at double-digit rates. In terms of end markets, Chemical and Energy returned to growth, Food grew double digits, and Pharma high single digits. LSAG remains extremely well-positioned and is outperforming the market. The Agilent CrossLab Group came in with revenues at $518 million. This is up a reported 9% and up 7% core. ACG's growth is also broad based across end markets and geographies. Our focus on on-demand service is paying off as activities in our customer labs continues to increase. The ACG team continues to build on its already deep connections with our customers, helping them operate through the pandemic and continue to drive improved efficiencies in lab operations. For the Diagnostics and Genomics Group, revenues were $294 million, up 9% reported and up 7% core.
Growth was broad based, with NASD oligo manufacturing revenues up roughly 40%. The Genomics and Pathology businesses continue to improve during the quarter. I'm also very proud of our NASD team for successfully ramping production at our new Frederick site this year. We have built a very strong position in this attractive market with excellent long-term prospects for high growth. Let's now shift gears and look at our full year fiscal 2020 results. Despite the disruption, uncertainty, and economic turmoil of dealing with a global pandemic, the Agilent team delivered solid results. We generated $5.34 billion in revenue, up 3% on a reported basis, and up nearly 1% core. To put this in perspective, it's helpful to recall the progression of our growth. In Q1, we delivered 2% core growth as we saw the first impact of COVID-19 in our business in China.
Both Q2 and Q3 declined low single digits as the pandemic spread across the globe and governments instituted broad shutdowns. With 6% core growth, 8% reported in Q4, we're seeing business and economy start to recover. As a result, we are clearly exiting 2020 with solid momentum. Our recurring types of businesses represented by ACG and DGG proved resilient, growing low to mid-single digits for the year. In a very tough CapEx market, our LSAG instrument business declined only 2% for the year and returned to growth in the final quarter. China led the way for our recovery, with accelerating growth as the year progressed. In our end markets, pharma remained the most resilient, and food markets recovered most quickly. Full-year earnings per share grew 5% during fiscal 2020 to $3.28. The full-year operating margin of 23.5% is up 20 basis points over fiscal 2019.
As we head into 2021, we do so with tremendous advantage. Our diverse industry-leading product portfolio has never been stronger. Our building and buying growth strategy with a focus on high-growth markets continues to deliver. Our ability to respond quickly to rapidly changing conditions is also serving us well. The way our Sales and Service teams have been able to quickly pivot to meet customer requirements during the pandemic has been nothing short of remarkable. Last year at this time, I used this call to remind you of the Agilent shareholder value creation model. Our approach is focused on delivering above-market growth while expanding operating margins, along with a balanced deployment of capital. We prioritize deployment of our capital both internally and externally on additional growth. A few proof points on our growth-oriented capital deployment strategy.
A year ago, we spoke about recently closing the BioTek acquisition and the promise of growth that BioTek represented. Today, BioTek is no longer a promise, but a driver of growth. In total, the Cell Analysis business generated more than $300 million in revenue for us during the year, with double-digit growth in Q4 and continued strong growth prospects. Similarly, last year, I was talking about ramping up our new Frederick site facility, a $185 million capital investment. In addition to successfully ramping Frederick as we planned, we did so with an expanding book of business. We also recently announced an additional $150 million investment to add future manufacturing capacity. We are aggressively adding capacity to capture future growth opportunities in this high-growth market. Even in the face of a pandemic, we stayed true to our build and buy strategy. We have clearly seen the advantages of our approach.
I'm confident our strategy will continue to produce strong results for us. The strength of our team and resilience of our business model has served us well. As you can see from the numbers, our growth strategy is producing outstanding results for our customers, employees, and shareholders. While uncertainties remain as we begin fiscal 2021, we're operating from a position of strength. Because of this, we're cautiously optimistic about the future. We have built and will sustain our track record of delivering results and working as a one Agilent team on behalf of our customers and shareholders. As I noted earlier, I couldn't be more pleased with the results the Agilent team delivered in the fourth quarter and throughout the year. Thank you for being on the call today, and I look forward to your questions. I will now hand the call off to Bob. Bob, you're up.
Thanks, Mike. Good afternoon, everyone. In my remarks today, I'll provide some additional revenue detail and take you through the fourth quarter income statement and some other key financial metrics. I'll finish up with our outlook for 2021 and the first quarter. Unless otherwise noted, my remarks will focus on non-GAAP results. We are very pleased with our fourth quarter results as we saw strong growth exceeding our expectations, especially considering the ongoing challenges associated with COVID-19. For the quarter, revenue was $1.48 billion, reflecting core revenue growth of 5.6%. Reported growth was stronger at 8.5%. Currency contributed 1.7%, while M&A added 1.2 points of growth. From an end market perspective, pharma, our largest market, showed strength across all regions and delivered 12% growth in the quarter.
Both small and large molecule businesses grew, with large molecule posting strong double-digit growth. We continue to invest and build capabilities in faster growth biopharma markets and offer leading solutions across both small and large molecule applications. The food market also experienced double-digit growth during the quarter, posting a 16% increase in revenue. While our growth in food business was broad-based, China led the way. As Mike noted earlier, our Chemical and Energy market exceeded our expectations, growing 3% after two quarters of double-digit declines. While one quarter does not a trend make, we are certainly pleased with this result, and the growth came primarily from the chemical and materials segment. Diagnostics and Clinical revenue grew 1% during Q4, led by recovery in the U.S. and Europe. We continue to see recovery in non-COVID-19 testing as expected, although the levels are still slightly below pre-COVID levels.
Academia and Government was flat to last year, continuing the steady improvement in this market. Revenue in the environmental and forensics market declined mid-single digits against a strong comparison from last year. On a geographic basis, all regions returned to growth. China continues to lead our results with broad-based growth across most end markets. For the quarter, China finished with 13% growth and ended the full year up 7%. Just a great result from our team in China. The Americas delivered a strong performance during the quarter, growing 5%, with results driven by large Pharma, Food, and Chemical and Energy. In Europe, we grew 2% as we saw lab activity improve sequentially, benefiting from our on-demand Service business in ACG, as well as from a rebound in Pathology and Genomics as elective procedures and screening started to resume.
However, while improving, CapEx demand still lags our Service and Consumables business. Turning to the rest of the P&L. Fourth quarter gross margin was 55%. This was down 150 basis points year-over-year, primarily by a shift in revenue mix and an unfavorable impact of FX on margin. In terms of operating margin, our fourth quarter margin was 24.9%. This is down 20 basis points from Q4 of last year as we made some incremental growth-focused investments in marketing and R&D, which we expect to benefit us in the coming year. The quarter also capped off a full-year operating margin of 23.5%, an increase of 20 basis points over fiscal 2019. Wrapping up the income statement, our non-GAAP EPS for the quarter came in at $0.98, up 10% versus last year. Our full-year earnings per share of $3.28 increased 5%.
In addition, our operating cash flow continues to be strong. In Q4, we had operating cash flow of $377 million, up more than $60 million over last year. In Q4, we continued our balanced capital approach, repurchasing 2.48 million shares for $250 million. For the year, we repurchased just over 5.2 million shares for $469 million and ended the fiscal year in a strong financial position with $1.4 billion in cash and just under $2.4 billion in debt. All in all, a very good end to the year. Let's move on to our outlook for the 2021 fiscal year. We and our customers have been dealing with COVID-19 for nearly a full year and are seeing our end markets recover. Visibility into the business cadence is improving, and as a result, we're initiating guidance for 2021.
There is still a greater than usual level of uncertainty in the marketplace across most regions. While we're providing guidance, we're doing so with a wider range than we have provided historically. It is with this perspective that we're taking a positive but prudent view of Q1 and the coming year. For the full year, we're expecting revenue to range between $5.6 billion-$5.7 billion, representing reported growth of 5%-7% and core growth of 4%-6%. This range takes into account the steady macro environment we're seeing. It does not contemplate any business disruptions caused by extended shutdowns like we saw in the first half of this year. In addition, we're expecting all three of our businesses to grow, led by DGG. We expect DGG to grow high single digits with the continued contribution of NASD ramp and the recovery in cancer diagnostics.
We believe ACG will return to its historical high single-digit growth, while LSAG is expected to grow low to mid-single digits. We expect operating margin expansion of 50 to 70 basis points for the year as we absorb the build-out costs of the second line in our Frederick, Colorado, NASD site. In helping you build out your models, we're planning for a tax rate of 14.75%, which is based on current tax policies, and 309 million of fully diluted shares outstanding. This includes only anti-dilutive share buybacks. All this translates to a fiscal year 2021 non-GAAP earnings per share, expected to be between $3.57 and $3.67 per share, resulting in double-digit growth at the midpoint. Finally, we expect operating cash flow of approximately $1 billion-$1.05 billion and an increase in capital expenditures to $200 million, driven by our NASD expansion.
We have also announced raising our dividend by 8%, continuing an important streak of dividend increases, providing another source of value to our shareholders. Let's finish with our first quarter guidance. Before we get into the specifics, some additional context. Many places around the world are currently seeing renewed spikes in COVID-19 that could cause some additional economic uncertainty. While we're extremely pleased with the momentum we have built during Q4, we are taking a prudent approach to our outlook for Q1 because of the current situation with the pandemic. For Q1, we're expecting a revenue to range from $1.42 billion-$1.43 billion, representing recorded growth of 4.5%-5.5% and core growth of 3.5%-4.5%. In first quarter 2021, non-GAAP earnings are expected to be in the range of $0.85-$0.88 per share.
Before opening the call for questions, I want to conclude by echoing Mike's comments about the amazing work the Agilent team performed during fiscal 2020. To be where we are now after knowing where we stood in March is truly remarkable. Add to this the strong momentum we saw in Q4, I truly believe we are well positioned to accelerate our growth in fiscal 2021. With that, Ankur, back to you for Q&A.
Thanks, Bob. David, let's provide the instructions for Q&A.
Certainly. As a reminder, to ask a question, you will need to press star one on your telephone. To withdraw your question, press the pound key. Please stand by while we compile the Q&A roster. Your first question comes from the line of Vijay Kumar with Evercore ISI. Your line is open.
Hey, guys. Congrats on the good prints here.
Hey, Vijay.
A couple of questions from me. Mike, maybe first on the guidance part here. I guess, the Q1 guidance of 4.5%-5.5% core, does it assume any COVID tailwinds? I guess you look at Q4, 6% core. Any reason why the core should slow down sequentially?
Yeah. Let me start with Bob. Again, thanks for the earlier comments, Vijay. How we characterize our Q1 guide is positive, but we use the word prudent approach. We got a lot of confidence in terms of we're reinstating the guidance. We had very good momentum in Q4, and we look at the backlog, we feel very confident about reinstating guidance. The virus is still out there, and we still think there's still a higher level of uncertainty that calls for a prudent approach. Hence the positive but prudent approach. If it turns out better, we'd love to be in a position of being able to raise our outlook for the year. We thought for the first guide for the year, including Q1, we should take a positive, prudent approach, just recognizing that the virus is still out there.
Bob, I don't know if you'd add anything to that.
Yeah, Vijay. I think a couple of things. The thing that I would say is we didn't end the year with emptying the tank out and feel really good about that. That being said, we do have some business that is somewhat susceptible to some of these areas, and so we probably have greater variability in some of our diagnostics businesses. As Mike said, we're taking kind of a prudent approach there. The other area is we want to see more than just 1/4 in the Chemical and Energy business. I think that's one of the areas where I think we think we're biased to the upside in the way we're kind of thinking about the business. Certainly with the recovery, we do expect some COVID tailwinds, to your point.
It's probably on the order of roughly about 1.5 points-2 points, kind of consistent with what we've seen in the last several quarters. That's kind of how we're thinking about it.
That's helpful, Bob. Mike, one bigger picture question for you. I think you mentioned NASD was up 40% in the quarter. Did that business accelerate NASD? I'm curious, the longer-term opportunity here when you think about it, can this end up being a half a billion-dollar product for Agilent as you look at four or five years out? I'm curious on your thoughts. Bob, I think you mentioned the 50 to 70 basis points of margin expansion inclusive of the investments in Frederick facility.
What do you think was the impact of those investments on the margins? Or I guess, what I'm asking is, what should margin expansion have been without those investments? Thank you.
Hey, Bob. Thanks for the question there, Vijay. How about I take the first part, and you can take the second part. That's not out of the realm of reason, your first question, in terms of the longer-term potential total revenue for Agilent. We kind of put a teaser out there earlier about our December analyst and investor day. We'll talk a bit more about NASD when we meet. As you know, we've talked about the past in terms of getting to that exit rate of over $200 million business. While our capacity in terms of physical capacity is built, we're now just finishing up the first year of operations. Just like we did with our Boulder site, we'll continue to find ways to drive more productivity and efficiency out of that asset.
We just announced another expansion of another production line within that existing facility. I hope what you're hearing is a very bullish tone, both in terms of the market growth, but also our ability to get even more of our unfair share, if you will, to capture share in a growing market.
Yeah, Vijay, this is Bob. Just to build on that, what Mike talked about, the beauty of that business is it continues to accelerate throughout the year. That roughly 40% growth in Q4 was the highest it was all year. That team has done just a fantastic job of scaling that business. We're not done. As Mike said, we're making incremental investments in building out that capacity, which we'll continue to make throughout the course of next year. That is probably about a 20 basis point headwind next year in the operating margin. Just rough numbers there, Vijay, but extremely pleased with the work that that team has been able to do and continuing to drive that growth. We feel very good about that business.
Thank you, guys.
You're welcome.
Your next question comes from the line of Puneet Souda with SVB Leerink.
Yeah, hi. Bob and Mike, thanks for taking the question. Bob, actually, one other question on guidance, and this is probably a favorite topic for you, the Chinese Lunar New Year.
Oh, yeah.
That's the year again, isn't it?
That time of the year. This time, obviously, you're seeing how the troops are acting on the ground, how things are there, and I would suspect it would be a lesser impact this year, lesser travel, but correct me if I'm wrong on that. In light of that, the guidance, again, appears conservative. Is there anything that we ought to keep in mind for a market that is growing double digit for you already and is a sizable portion of your revenue? Just walk us through how you're thinking about the Lunar New Year impact here.
Yeah, that's great. Great question, Puneet, as you accurately state, our expectation is the impact's going to be much less this year than it was last year for all the things that you just talked about, less travel, timing of when it is, and so forth, relative to Q1. What we're seeing is actually very strong continued recovery and performance in our China business, and I would say that Q1 is no different. The story there certainly remains intact, and I would expect it to be very strong performance in Q1. I think what we're trying to do is, there's nothing in particular, but I think we're just probably taking a little more prudent approach in Europe, as we're seeing some of the shutdowns, particularly in some of these areas.
I think as we look at where are the things that could potentially be upsides or downsides, I think the continued recovery in Chemical and Energy across the business. Continued performance in Americas. We're expecting kind of an average budget flush, so to speak. That's another question that probably if people are thinking about for the end of the year. Both of those things could be better than expected.
Yeah, Bob, if I could just jump into that just to amplify the point, Puneet, that Bob made. We're very happy with our China business, we exited the year with momentum, and that's carrying forward into 2021. We're positioning ourselves with a wait-and-see moment on C&E, that could be a source of upside for the year. As I said earlier, we're fully prepared to reflect that in a revised outlook. I would just use the word maybe prudent as a way to describe, as the adjective Bob and I have been using to describe our guide.
Okay. That's very helpful. Thanks. If I could get a sense on the Cell Analysis business. That business continues to be really strong for you. BioTek, ACEA, Seahorse, other products in that product line. Just wanting to get a sense of what are some of the key drivers there? Is it largely the cell and gene therapy, the cellular product, drug product market? Is there something in the academic end that is driving that growth, or especially in China? Would appreciate in helping frame what's exactly happening there and the opportunity there longer term.
Yeah, Puneet, thanks for the question, and as I mentioned in my call script, we're really pleased with how we've been able to integrate the BioTek team, make them part of the Agilent family, and then how that collected has led to have a very healthy Cell Analysis business north of $300 million, growing nicely for us. I know that Jacob would love to have an opportunity to talk a little bit more about the Cell Analysis there. Jacob, your thoughts on the specific questions that Puneet put forward?
First of all, let me just echo that I think it's been very impressive what the team has been doing here the past year. The growth actually stems from multiple dimensions here. First of all, we have seen for serology testing that a lot of our BioTek portfolio has been using for that, for the ELISA testing. We also see, generally speaking, imaging being very relevant in the academic markets, but also in the biopharma markets and the ACEA portfolio with the Flow Cytometry is also seeing quite a lot of interest. It's really broad across both academic and biopharma and COVID related that we see interest. Like Cell Analysis, it was where we felt a few years ago that this was an area that would be continued to see a lot of growth, particularly at that point about immuno-oncology.
Clearly that has moved into a broader understanding on the immune system right now with COVID. Generally speaking, I think this will be a focus for many years to come. Very pleased, and we continue to expect good growth in that business.
Yeah. Hey, Puneet, just one thing, because you mentioned China, we see really China as a huge opportunity for us going forward. The real growth has been primarily in the U.S. and Europe. It's growing in China as well, it's off a very small base.
When we think about the opportunities going forward, leveraging the large infrastructure that Agilent has, is really a big opportunity for us for many years to come in the Cell Analysis space.
Great. Okay. Thank you.
The next question comes from the line of Tycho Peterson with JP Morgan.
Hey, good afternoon. Mike, I'm wondering if you could talk a little more on the biopharma strength. 12% on a 7% comp is obviously phenomenal. I know you had 2% from NASD, and you just talked about Cell Analysis, but can you maybe just talk more broadly on the strength in biopharma? Was any of this a catch-up from slower spending in the first half of the year, and how do you think about the sustainability of the demand? I know you mentioned you're thinking about an average budget plus, but can you just talk to the broader strength in biopharma?
Yeah, sure. Happy to do so, Tycho. Without giving away too many of the tidbits that I want to talk about in more depth in a few weeks, there was no catch-up here. This is part of this continued strength in the biopharma area. It's been an area of focus. We'll go into some more detail with you in a few weeks. It's been an area of focus in terms of increased investments relative to our biopharma tools, both the instrumentation along with the chemistry platform, a real workflow focus there across the whole value chain. We're getting nice growth, as you mentioned earlier, on NASD. The story is much bigger than that, to be honest with you. Obviously, we're picking up some growth here in the Cell Analysis. I think it's really a multifaceted strategy that's really driving this growth.
We think it's sustainable. We think a double-digit outlook on the biopharma portion of Agilent business is quite reasonable. We're really excited and it's an investment priority for us.
Yeah, Tycho, maybe if I can add to Mike's point in terms of, because it's not only the platforms in the portfolio that we have on the instrument bases, which we've been making some heavy investments in it, but it's also been the informatics and the software piece, which has allowed us to be able to kind of plug into the labs, the analytical labs, and then you bring in the ACG services portfolio to help them manage the labs. Particularly with everything that's going on right now, the last thing they want is their scientists to be managing the instrumentation. They want them to be doing the science.
Great. Mike, you used the phrase wait and see moment for C&E a couple of minutes ago, it's good to see that back to growth. Can you maybe just talk on some of the data points you're watching in your customer base and how you're thinking about the recovery curve there?
Yeah. Thanks for Tycho. I kind of must come back from my first year as a CEO when I tried to call the turn of the C&E business, and eventually it turned, but I think I was off by several quarters. I learned my lesson, so to speak. As Bob mentioned, one quarter a trend does not make, but we're very encouraged by that because it's the first time we've seen some growth after those two double-digit declines earlier this year. We look at a couple of things, Tycho. One is just the PMIs. The positive moves in the PMIs are indicative of improved end market strength, particularly in C&E. We also look at what we estimate to be the age of the installed base, because there's a lot of aged equipment out there, and that's been probably at very high levels.
We look at the deal flow. With kind of all those factors, the macro outlook from PMIs, what we know to be the current environment for customers in terms of the age of their installed base, what we're seeing in our funnels. As you know, Agilent has a real strength in this market, so I think we will benefit from a return here to growth. Again, we weren't ready yet to put it into numbers for Q1 and the full year. We're hopeful that trend will continue. There's some indications that it could, but let's give it another quarter or so.
Okay. Lastly, before I hop off, one quick one on China. One of the other tools companies, Mettler-Toledo, talked about pent-up demand and kind of suggested that what they saw may not be sustainable. Have you seen anything in your order book that would suggest?
No.
What you're seeing in China now is not sustainable?
Yeah, no, Tycho, I really appreciate you asking that question because not at all. I mean, this has been a continuing steady flow of business. We think the end markets are really strong here. We see a lot of strength in China government funding to make sure they stimulate the economy. We've talked earlier about just overall, their investments in improving the quality of life. You notice the strong growth in the Food market, continued strength in Pharma. No, we've seen this. Bob, I think we've really looked closely at the pacing, and we saw nothing unusual.
Yeah. Tycho, I think we've been extraordinarily pleased with the way our China business has performed throughout the course of this year. When you think about kind of our cadence through Q1, two, three, and four, we've seen accelerated growth. We saw our lowest growth in the first quarter where we saw the impact of COVID-19, but then what we've seen is improvements as opposed to this real huge increase and then kind of a drop-off. We're not expecting any drop-off, and we haven't seen that in our order book or any of the conversations that we've had with our customers, that there was sort of a material catch-up.
Okay. Thank you.
You're quite welcome, Tycho.
The next question comes from the line of Brandon Couillard with Jefferies. Your line is open.
Hey, thanks. Good afternoon.
Hey, Brandon.
Mike, a couple questions on LSAG.
Sure.
Curious if you could speak to the order book in the fourth quarter and to the extent that you may have built some backlog there. Curious if you speak to perhaps the margin compression in the fourth quarter, whether that was mostly mix or if you could elucidate some of the dynamics there?
Happy to do so, Brandon. One of the reasons why we were able to reinstate guidance this year was what we saw in the LSAG order book. As you know, we stopped a few years ago talking about specifics around orders. I think in today's call, it's really prudent just to give you a sense of why Bob and I have this confidence around the outlook. We didn't gasp as we ran across the finish line for 2020. Order book was strong in LSAG, and it's continued into the early few weeks of this year. All the other caveats aside, being prudent in recognition of the virus, we feel pretty good about our ability to reinstate guidance because as we mentioned earlier.
As we mentioned earlier, LSAG was one where we hit the most early in the year, and I think we're feeling pretty good about that. Bob, as I recall, most of the gross margin is really just a mix relative to various instrument platforms.
Yeah, that's right. I think, Brandon, to reiterate what Mike is saying, we feel very good. Orders exceeded revenue.
Exceeded our expectations. It was a bit of a mix shift that is impacting that, but we would expect that to normalize out throughout the course of next year.
feel very good about where that business is going into 2021.
Yeah. Brandon, just one additional thought here, which is we've seen no real changes in the pricing environment. That's why we can stay pretty calm. It's just that it happened to be the mix of the products this quarter.
Super. Then one more for Bob. You mentioned currency was a drag to margins in the fourth quarter. Could you quantify that, the magnitude at the operating line, then what you penciled in for impact of FX to operating margins in 2021 would be helpful.
Yeah. It was roughly about 40-ish, 45-ish on the COGS line, some of that was offset through the bottom line. For next year, much less impactful than that. Probably less than about 10 basis points.
Super. Thanks.
You're welcome.
Your next question comes from the line of Dan Leonard with Wells Fargo. Your line is open.
Thank you. To start off on the guidance, a question for probably you, Bob. You've touched on this in pieces, but can you give us at a high level what your key assumptions are by region and by end market?
Yeah. At the highest level, we are expecting steady improvement throughout the course of the year from the standpoint of the economic perspective. If I think about it from a geography first, China's going to lead the way with high single-digit growth, continuing the momentum that we've seen. We ended this year, FY 2020, about 7%, and we're expecting that or better into next year. What you would see is a recovery in the Americas, getting back to mid to high single digits, and then followed by Europe, which would be low to mid single digits. That's on an end-market perspective, how we would think about it. It's predicated on that continued recovery and that we would, as I mentioned before, not have any extended periods of shutdown that would disrupt business.
I think the good thing is what we are seeing, not only ourselves, but our customers are being able to operate in a different environment than they had the first time these were shut down. We are not expecting any material impact there. From an end-market perspective, the strength is really going to be the continued strength that we have seen in the last several years, really driven behind our Pharma business, which is probably high single digits. With biopharma, as one of the earlier questions came out, probably growing double digits, going forward. Food, we will probably expect maybe a little tempering, where it would be great to have 16% every quarter, but we are not ready to put that into our plan. I would expect continued recovery there, probably in the mid-single digits.
Also recovery in our Diagnostics and Clinical business, particularly in that same mid-single digits, and probably ramping throughout the course of the year. Probably more muted on the Academia and Government, probably flattish to low. As we talked about before, Chemical and Energy, flattish, but that's really one where we're hoping that we're biased, and there's more upside than downside here. Certainly given the momentum, one quarter is too early to put a forecast on there. We're assuming roughly flat, and then probably a recovery in the environmental and forensic market at low single digits.
Okay. Thanks for that overview. For my follow-up, you touched on there being a wider range of outcomes in 2021 than typical and mentioned that the bottom end doesn't capture any threats around reestablishment of lockdowns or whatnot. Do you feel the high end of guidance really captures all the benefits from easy comparisons and any potential upsides there might be, or how would you frame what you're capturing in the high end there?
Yeah. I would say it's continued momentum, but I think that there's probably more upsides than downsides in the way that we're trying to capture that.
Yeah.
Certainly, exiting at a 6% growth rate, probably the biggest areas are around Chemical and Energy and the pace of recovery in Academia and Government. If those continue, let me put it this way, if Chemical and Energy continued at 3% and growing, we'll beat that number.
Yes, absolutely.
Thank you.
Thanks, Dan.
Your next question comes from the line of Douglas Schenkel with Cowen. Your line is open.
Hey, good afternoon, guys.
Good afternoon, Doug.
I have a few cleanup guidance questions, but before I get to that one, I just wanted to talk about your performance, specific to your Mass Spectrometry product line. You talked about another quarter of double-digit growth. I'm just wondering if you'd be willing to unpack that a bit more and just talk about what's driving this. Specifically, is China and more specifically China food, a major driver? I guess I'm just trying to get at which segments of the portfolio or specific end markets or geographies that really stand out within a pretty robust and impressive growth rate there.
Hey, Doug, really appreciate the opportunity to have Jacob comment more deeply on that. As you know, I highlighted that in my script. We were able to call out that double-digit growth. We're extremely proud of that. Jacob, I think you've got some additional insights maybe you could share with Doug.
Yeah, absolutely. This is a great question, and I'm certainly proud of what the team has been doing over the past years because this is not only a quarterly effect here, but we have done quite an overhaul of our Mass Spectrometry portfolio, particularly the LC-MS portfolio over the last few years, both on the high-end triple quad, but also the single quad. You've seen we have really been focusing on robust, reliable, and routine applications, and this is really what the customers are looking for right now. You can really see that the investments we have done really resonate with our customer base, and it's right now, I would say, in most geographies and in most end markets. If you look into it's biopharma, and China is definitely a big part of this story.
The other element to it is that we pivoted very quickly to remote customer engagement during the beginning of this year. When the customer had to shut down the laboratories, we were there for them. We did support them when they were in the tough times, and you can see that paid dividends today, that they also continued with the partnership with Agilent. I actually believe that we are in a quite good momentum here with the Mass Spectrometry business.
Yeah.
All right.
That help, Doug?
Yeah, that sure does. Thank you for that. Maybe just a few guidance questions. This'll be kind of a speed round in a way, because you have got some questions about these already. On China, do you expect double-digit growth in fiscal 2021? On gross margin, you talked about some of the headwinds you saw in Q4 becoming less pronounced moving forward. Do you expect gross margin overall to get back up to the 56%+ level? On COVID-19, I think you talked about just over two points of COVID tailwinds in the quarter. I'm just wondering if looking forward, either fiscal Q1 or for the full year, if you could see a scenario where this would accelerate over time if serology volumes begin to inflect in a positive way. Same thing on the antibody business.
Could those in combination drive more of a tailwind moving forward? China, gross margin, and COVID-19.
China, high single digits, maybe low double digits based on the range that we gave you. In terms of COVID, what I would say is we are expecting less incremental to growth, but certainly the things that you talked about aren't baked into our guidance. More serology or antigen-based testing or even vaccine-driven volume is not fully baked into the numbers that we are. It's just too early to tell. Those are certainly the things that are potential upsides. The last one, which was your second question around gross margin, I would expect it to stabilize and not see the same level of decline. Now, what I would say is you will have some mix shift, right? Because our ACG business, which is lower gross margin than the instrument business, but much higher operating margin, helps us with that.
You do see a dampening effect on the gross margin side, but you will more than make up for it on the operating margin side.
Okay. Sorry.
Doug, specifically to COVID-19, we'll hit a little bit more of that when we have our Analyst Day, but we are planning to launch in early 2021 our serology test. There are some things that we're working on that aren't baked into the guidance. We'll see how they play out.
Okay. That's great. Thank you guys for all the time, and happy Thanksgiving, everybody.
Same to you.
Thank you. Your next question comes from the line of Derik De Bruin with Bank of America. Your line is open.
Hey, good afternoon.
Hey, Derik.
Hey, Derik.
Hey. I'm going to do this similar to Doug. I've got a couple of focus questions. I got one guidance cleanup. I guess specifically, Bob, you mentioned some software pushes in your business between the Pharma business. Can you be a little bit more specific on that? I mean, is OpenLab taking share against Empower? Are you winning? Have you replaced Empower in some of the accounts there? I'm just sort of curious on what the dynamics are in the CDS market.
Yeah, what I would say, Doug, or excuse me, Derik, is that we feel very good about our competitive positioning with OpenLab and the rest of our products.
Okay. I'll live with that, I guess. Yep. By the way, I'm better looking than Doug. On the core Genomics business, we don't really have talk about that. You talk about the NASD and some of these other things there, what's going on in your core Genomics business? You've got SureSelect. You've had some pressures in some of that end market there. What's that underlying business growing?
Yeah, actually, a great question because we didn't highlight that. Actually, when you look at sequential performance, that was one of the things that was very positive in the DGG business. It recovered very nicely into Q4. Maybe I'll let Sam talk about some of the details there.
Yeah, sure. Thanks, Bob. As you said, as we went into the heavy part of the pandemic, if you will, late Q2, early Q3, some of the Genomics business also serves Clinical/D iagnostic customers, be it for SureSelect being the backbone of some of the leading cancer diagnostic NGS-based tests, as well as other inherited diseases. We definitely saw the effect of that. Coming into Q4, we've seen a steady stream of increase there.
We've also seen a positive effect in parts of our portfolio that are related to qPCR, be it our instruments, be it our consumables that are used. Also, we have the leading Genomics QC portfolio, as you're probably aware of. We see a number of those products, including our Fragment Analyzer, being used increasingly with the pickup of conventional clinical testing, but also being used, for example, for some of the mRNA vaccines that are in development. All in all, the trend is looking encouraging for our core Genomics business.
Great. just one housekeeping question. For 2021, the other income expense line, how should we think about that for 2021?
Bob, do you want me to handle that, or you want to take that?
Yeah, it'll be slightly better than where it is this year.
Okay. Thank you.
Your next question comes from the line of Jack Meehan with Nephron Research. Your line is open.
Hello, Jack.
Hey, good afternoon. I wanted to go back to biopharm. Mike, I was curious if you're seeing any change in terms of customer spending patterns at all because of COVID-19. There's just been such a focus on bioprocessing to support vaccines and therapeutics. What's that doing in small molecule, if you can call out any trends?
Jack, great question. To our delight, it really hasn't seemed to cause any kind of material shift. In fact, I think Bob highlighted in his script where we saw strength across small molecule and large molecule. The small molecule's not growing as fast as large molecule. It was growing. Bob,
Yeah. Jack, to give you some numbers, for Q4, small molecule grew high single digits, and for the year, it grew low single digits. Despite all the hoopla, small molecule is not dead.
Yeah.
Great. Maybe just to build on that. The high teens ACG growth in China, could you just parse out for us how did food do versus how did maybe generics do in terms of some of the consolidation there?
As Bob, as I recall, I'll invite Padraig on this one, I think it was broad-based across all end markets. Everything was in that double-digit range. Padraig, anything you'd add to that?
Yeah, no. I think you said it well, Mike. I think across both sides of the business, both the chemistries and services, very strong demand in all markets. We see certainly a strong demand for our installation, familiarization, and startup services. Really strong across the board in China.
Great. Thank you, guys.
Your next question comes from the line of Patrick Donnelly with Citi. Your line is open.
Hey, guys. Thanks for taking the question. Maybe just a follow-up on Mike, just on the Chemical and Energy side, it certainly sounds like that's the biggest area of upside, maybe the biggest variable for next year. Sounds like chemicals and materials, things are improving. Can you just give a bit more detail around the customer tone there? Then is energy the bigger variable to 2021? Maybe just talk through the scenario analysis as you guys think about it. It certainly seems like there's upside, maybe just what parts of the business you feel like are the biggest variables there.
First of all, this is always a helpful reminder, but our mix. It's at 70/30. 70/30 in chemicals and materials and 30% energy. I actually have the upsides on the chemicals and material. Energy lags, and we aren't really seeing a lot of indications of why that would pick up. You have to remember, some of the chemical companies are actually providing products and such into end markets that support COVID-19. What drives this marketplace, yes, we talk about PMIs, but really the PMIs are really related to the view of global growth. I think that customer base is feeling more confident about where the economy is going. Things just really slowed down earlier this year just for must purchases.
I think it's the improved view of the overall economic outlook for the chemicals and materials side, plus the fact that they have some COVID-19 tailwinds that are helping out. I wouldn't say that's the entire story. It's just an element of it. I think the biggest part here is just the fact that there's much more confidence in the customer base about the growth environment from an economic standpoint. Anything you'd add to that?
I think you're right.
Okay. No, that's very helpful. Maybe just on the capital deployment side, I know you guys always take the balanced approach, and I'm sure we'll hear more about it in a couple of weeks. How are things trending in the pipeline on the M&A side? Cash flow has actually been pretty strong. How active should we expect you guys to be on that front? Any changes in thoughts around the size of deals you want to pursue, and any metrics you could throw out there to help with facts?
No, we continue to be very interested in deploying capital for growth standpoint along all the dimensions we talked about earlier. We said that the BioTek size deal, which we were really quite happy with, that was the largest deal we've done to date. That doesn't mean that would be the largest deal we would do. We've always said, I think multiples, not magnitudes of delta. Although we didn't close any deals this year, I think that really was somewhat tied into some of the COVID-19 challenges of doing due diligence and working with potential targets. We still see this as a key part of what we call our build and buy growth strategy, and think that M&A can be a nice adder to our core growth businesses. You guessed right.
We'll talk more about it in a few weeks, but we still have aspirations in this space, but really sticking to the model and the framework that we've been using before, which is M&A in markets that are higher growth than the rest of the company, that align strategically with us, where they can benefit by our scale and are accretive to the P&L.
Yeah, I would say, Patrick, just to build on what Mike was saying, we feel very good about the acquisitions that we made. The last two, which was BioTek and ACEA, were probably the fastest-growing bit parts of our business if you take out NASD. I think it validates the space that we're looking at, and we don't see a reason to need to change our M&A framework.
Okay. Thanks, guys.
Your final question comes from the line of Steve Beuchaw with Wolfe Research. Your line is open.
Hi. Thanks for sneaking me in here.
All right.
I'll just ask one, maybe I guess it's a two-parter. One part for Mike, one part for Bob.
Okay. Hope you give me the easy one.
I think you're going to like it.
Okay.
Mike, the last call, you raised this concept, you called it a flight to quality. You talked about how the team with their execution has been able to drive share gain. I wonder if you could talk about whether you think that as the pandemic subsided in some ways and labs are opening up again, if you think that dynamic has become any more or less acute, and if you think it's sticky. I'm going to go ahead and ask the second part of my, I guess I'll call it COVID discovery question for Bob. Bob, like a lot of CFOs, you've had a chance to see how much you can save within operating expenses as we're all working remotely and being more digital. Have you thought about putting any numbers around how much of the savings that you've discovered here could end up being permanent?
Thanks a bunch, everybody.
Sure. Yeah. Thanks, Steve. In regards to the first one, we probably talked about the flight to quality when money is tight. We also, I think, tied it to the stability and how we protected our overall field team and our ability to support our customers during the pandemic. I think those two things are going to carry us forward. We think that the stickiness will remain there. I don't think that the quality will fall out of fashion. I think as you continue to grow your position in the install base, this gives you an upper hand in terms of the next buy when they get around to making the next capital purchasing decision.
Yeah. I would agree with that, Mike. I think two things. One is we were there when the customers needed us the most, and our team, particularly in the field, helping support critical operations and so forth. That flight to quality on the instrumentation side only pays dividends going forward. I think there will be no fall off there. I truly believe that. On the cost side, we're still working through some of those things. A big thing, probably the biggest variable here, and it's got a couple of different tentacles to it, would be around travel. I think we had talked about before, at one point in time, we were spending roughly $10 million a month in travel, and that is down, I would say, substantially. Our goal is that won't be back to $10 million a month.
That doesn't say that we're going to necessarily drop it all to the bottom line, but reinvest in some areas that will drive growth going forward. Certainly, there will be more efficient ways of doing things like marketing, outreach to our customers, and even operating. One of the things is we still operated and launched new products despite not having been in the labs for the most part for nine months out of the year. Our teams are finding innovative ways to continue to actually move things around without having to spend incremental dollars. More to come on that.
Yeah, we think some of these are going to stick.
Yeah.
Particularly as it relates to your digital engagement with customers because there's a huge element of being responsive. We think that digital cable is a big part of that story. Yes, it has been accelerated by COVID, but we don't think there's any going back either.
Got it. Thank you for all the color there, guys.
You're quite welcome.
Ladies and gentlemen, this concludes today's conference call. Thank you for participating. You may now disconnect.