Actuate Therapeutics, Inc. (ACTU)

NASDAQ: ACTU · Real-Time Price · USD
2.935
-0.040 (-1.34%)
May 12, 2026, 3:33 PM EDT - Market open
Market Cap69.59M -60.2%
Revenue (ttm)n/a
Net Income-22.23M
EPS-1.06
Shares Out 23.71M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume108,029
Open2.860
Previous Close2.975
Day's Range2.850 - 3.085
52-Week Range1.580 - 11.990
Betan/a
AnalystsStrong Buy
Price Target17.50 (+496.25%)
Earnings DateMay 14, 2026

About ACTU

Actuate Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops therapies for the treatment of cancers in the United States. The company’s lead product candidate is elraglusib injection, a glycogen synthase kinase-3 inhibitor that is in Phase 2 trial to treat metastatic pancreatic ductal adenocarcinoma. It also develops elraglusib, which is in Phase 1/2 trial for the treatment of refractory pediatric malignancies, including Ewing sarcoma, as well as neuroblastoma and pediatric leukemias. The company was formerly known as Apothe... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Aug 13, 2024
Employees 12
Stock Exchange NASDAQ
Ticker Symbol ACTU
Full Company Profile

Financial Performance

Financial Statements

Analyst Summary

According to 2 analysts, the average rating for ACTU stock is "Strong Buy." The 12-month stock price target is $17.5, which is an increase of 496.25% from the latest price.

Price Target
$17.5
(496.25% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Actuate Therapeutics receives FDA clearance for oral elraglusib study

Actuate Therapeutics (ACTU) announced the FDA has cleared its investigational new drug application to conduct a Phase 1/2 study of oral elraglusib in advanced cancer patients. The study is designed…

1 day ago - TheFly

Actuate Therapeutics Announces FDA Clearance of IND for Oral Elraglusib and Strategic Initiatives to Advance the Elraglusib Development Program

Elraglusib oral tablet formulation to drive next-phase clinical development and broader clinical use FDA cleared IND for Phase 1/2 study of oral elraglusib in advanced cancer patients, with focus on m...

1 day ago - GlobeNewsWire

Analysts see 200%+ upside in these 3 high-risk stocks: here's why?

Some of Wall Street's biggest upside calls are not sitting in the mega-cap names. They are hiding in small, volatile stocks with thin balance sheets, limited operating history and one big event ahead.

Other symbols: ATAIVVOS
3 days ago - Invezz

Actuate Therapeutics Announces Key Appointment of Industry Veteran to Board of Directors

Martin Huber, MD brings deep expertise in oncology drug development, regulatory strategy, and commercialization of novel therapies Martin Huber, MD brings deep expertise in oncology drug development, ...

6 days ago - GlobeNewsWire

Actuate Therapeutics management to meet with B. Riley

Meeting to be held in Dallas on May 5 hosted by B. Riley.

12 days ago - TheFly

Actuate Therapeutics drug improves survival odds in pancreatic cancer trial

Twice as many advanced pancreas cancer patients who received an experimental drug developed by Actuate Therapeutics with chemotherapy were alive after one year as those treated with chemo ​alone, acco...

20 days ago - Reuters

Actuate Therapeutics Announces Nature Medicine Publication of Clinical Trial Results Showing Doubling of the Rate of Survival with Elraglusib Plus Chemotherapy in Previously Untreated Metastatic Pancreatic Ductal Adenocarcinoma

CHICAGO and FORT WORTH, Texas, April 14, 2026 (GLOBE NEWSWIRE) -- Actuate Therapeutics, Inc. (NASDAQ: ACTU) (“Actuate” or the “Company”), a clinical-stage biopharmaceutical company focused on developi...

4 weeks ago - GlobeNewsWire

Actuate Therapeutics price target lowered to $15 from $20 at H.C. Wainwright

H.C. Wainwright analyst Swayampakula Ramakanth lowered the firm’s price target on Actuate Therapeutics (ACTU) to $15 from $20 and keeps a Buy rating on the shares. The firm adjusted the…

4 weeks ago - TheFly

Actuate Therapeutics: Poised for Potential $200M+ Pediatric Priority Review Vouchers and Transformative Combinations in RAS-Driven Cancers

Meg Flippin, Benzinga Staff Writer CHICAGO, IL AND FORT WORTH, TX / ACCESS Newswire / March 24, 2026 / Actuate Therapeutics, Inc. (NASDAQ:ACTU) is a clinical-stage biopharmaceutical company advancing ...

7 weeks ago - Accesswire

Actuate launches research initiative to combine elraglusib, RAS inhibitors

Actuate Therapeutics (ACTU) announced the launch of an expanded research initiative evaluating combinations of its clinical-stage GSK-3beta inhibitor elraglusib with emerging RAS-targeted therapies. D...

2 months ago - TheFly

Actuate Therapeutics Launches Strategic Research Initiative to Combine Elraglusib with RAS Inhibitors

CHICAGO and FORT WORTH, Texas, March 09, 2026 (GLOBE NEWSWIRE) -- Actuate Therapeutics, Inc. (NASDAQ: ACTU) (“Actuate” or the “Company”), a clinical-stage biopharmaceutical company focused on developi...

2 months ago - GlobeNewsWire

Actuate Therapeutics to Present at the Oppenheimer 36th Annual Healthcare Life Sciences Conference

CHICAGO and FORT WORTH, Texas, Feb. 24, 2026 (GLOBE NEWSWIRE) -- Actuate Therapeutics, Inc. (NASDAQ: ACTU) (“Actuate” or the “Company”), a clinical-stage biopharmaceutical company focused on developin...

2 months ago - GlobeNewsWire

Actuate Therapeutics announces plans to expand clinical pipeline

Actuate Therapeutics (ACTU) announced plans to initiate a Phase 1/2 clinical program evaluating the oral tablet dosage form of elraglusib in patients with advanced cancer. The phase 1 portion of…

3 months ago - TheFly

Actuate Therapeutics says Phase 2 study met primary endpoints

Actuate Therapeutics (ACTU) announced that new additional and promising patient survival and biomarker data from treatment with elraglusib for metastatic pancreatic cancer were featured in oral and po...

4 months ago - TheFly

Actuate Therapeutics Reports Positive Follow-Up Data from its Randomized Controlled Phase 2 Trial Demonstrating Extended Long-Term Overall Survival Benefit with Elraglusib Plus Chemotherapy for Metastatic Pancreatic Cancer in Oral Presentation at ASCO GI 2026

CHICAGO and FORT WORTH, Texas, Jan. 12, 2026 (GLOBE NEWSWIRE) -- Actuate Therapeutics, Inc. (NASDAQ: ACTU) (“Actuate” or the “Company”), a clinical-stage biopharmaceutical company focused on developin...

4 months ago - GlobeNewsWire

Actuate announces results from Phase 1 portion of study of elraglusib

Actuate Therapeutics (ACTU) announced results from the phase 1 portion of its phase 1/2 clinical study evaluating elraglusib as a monotherapy or in combination with irinotecan, irinotecan plus temozol...

4 months ago - TheFly

Actuate Therapeutics Announces Positive Patient Outcomes from Phase 1 Trial in Difficult-to-Treat Refractory Pediatric Cancers

CHICAGO and FORT WORTH, Texas, Jan. 06, 2026 (GLOBE NEWSWIRE) -- Actuate Therapeutics, Inc. (NASDAQ: ACTU) (“Actuate” or the “Company”), a clinical-stage biopharmaceutical company focused on developin...

4 months ago - GlobeNewsWire

Actuate Therapeutics Phase 2 Metastatic Pancreatic Cancer Data Selected for Oral and Poster Presentation at ASCO GI 2026

CHICAGO and FORT WORTH, Texas, Dec. 18, 2025 (GLOBE NEWSWIRE) -- Actuate Therapeutics, Inc. (NASDAQ: ACTU) (“Actuate” or the “Company”), a clinical-stage biopharmaceutical company focused on developin...

5 months ago - GlobeNewsWire

Actuate Therapeutics announces publication of Phase II data for elraglusib

Actuate Therapeutics (ACTU) announced the publication of new data in Clinical Cancer Research from a Phase II study evaluating elraglusib in combination with carboplatin or cisplatin in patients with ...

5 months ago - TheFly

Actuate announces corporate update on regulatory path for elraglusib

Actuate Therapeutics (ACTU) announced a corporate update on the regulatory path for elraglusib in pancreatic cancer and anticipated milestones enabled by the recent $17.25M public offering. Actuate ha...

8 months ago - TheFly

Actuate Therapeutics Provides FDA with Updated Clinical Data Package to Support Planned Regulatory Interactions with FDA and EMA Over the Coming Months

CHICAGO and FORT WORTH, Texas, Sept. 22, 2025 (GLOBE NEWSWIRE) -- Actuate Therapeutics, Inc. (NASDAQ: ACTU) (“Actuate” or the “Company”), a clinical-stage biopharmaceutical company focused on developi...

8 months ago - GlobeNewsWire

Actuate prices 2.14M shares at $7.00 in underwritten public offering

Actuate Therapeutics (ACTU) priced an underwritten public offering of 2,142,858 shares of its common stock at an offering price of $7.00 per share of common stock. Actuate has granted the…

8 months ago - TheFly

Actuate Therapeutics 2.142M share Secondary priced at $7.00

acted as lead book running manager for the offering.

8 months ago - TheFly

Actuate Therapeutics Announces Pricing of $15.0 Million Public Offering of Common Stock

CHICAGO and FORT WORTH, Texas, Sept. 10, 2025 (GLOBE NEWSWIRE) -- Actuate Therapeutics, Inc. (NASDAQ: ACTU) (“Actuate” or the “Company”), a clinical-stage biopharmaceutical company focused on developi...

8 months ago - GlobeNewsWire

Actuate Therapeutics announces common stock offering, no amount given

Actuate Therapeutics (ACTU) announced that it intends to offer and sell shares of its common stock in an underwritten public offering. The company intends to use the net proceeds from…

8 months ago - TheFly