Alnylam Pharmaceuticals Ratios and Metrics

Market cap in millions USD. Fiscal year is January - December.

Millions USD. Fiscal year is Jan - Dec.

Fiscal Year	Current	FY 2025	FY 2024	FY 2023	FY 2022	FY 2021
Period Ending	Apr '26 Apr 27, 2026	Dec '25 Dec 31, 2025	Dec '24 Dec 31, 2024	Dec '23 Dec 31, 2023	Dec '22 Dec 31, 2022	Dec '21 Dec 31, 2021
Market Cap	40,547	52,639	30,424	24,078	29,451	20,381
Market Cap Growth	28.75%	73.02%	26.36%	-18.24%	44.51%	34.69%
Enterprise Value	40,582	50,964	28,984	22,903	28,537	18,902
Last Close Price	305.73	397.65	235.31	191.41	237.65	169.58
PE Ratio	131.13	170.67	-107.94	-54.38	-25.55	-23.55
Forward PE	46.24	60.03	-	-	-	-
PS Ratio	10.91	14.17	13.53	13.17	28.39	24.14
PB Ratio	51.25	66.70	453.50	-109.13	-186.13	34.65
P/TBV Ratio	51.71	67.86	447.73	-108.36	-182.78	34.15
P/FCF Ratio	87.07	113.11	-714.37	574.04	-48.02	-28.38
P/OCF Ratio	77.32	100.44	-3660.27	231.18	-54.41	-31.76
EV/Sales Ratio	10.93	13.72	12.89	12.53	27.51	22.39
EV/EBITDA Ratio	72.83	91.46	-241.10	-100.40	-38.53	-28.59
EV/EBIT Ratio	80.91	101.61	-163.86	-81.17	-36.35	-26.67
EV/FCF Ratio	87.20	109.51	-680.55	546.02	-46.53	-26.32
Debt / Equity Ratio	1.56	1.56	18.69	-5.73	-8.08	1.63
Debt / EBITDA Ratio	2.29	2.29	-10.78	-5.72	-1.78	-1.51
Debt / FCF Ratio	2.75	2.75	-30.43	31.12	-2.15	-1.39
Net Debt / Equity Ratio	-2.07	-2.07	-20.84	5.14	5.51	-2.44
Net Debt / EBITDA Ratio	-2.92	-2.92	11.63	4.97	1.18	2.17
Net Debt / FCF Ratio	-3.50	-3.50	32.84	-27.03	1.42	2.00
Asset Turnover	0.81	0.81	0.56	0.50	0.29	0.24
Inventory Turnover	8.46	8.46	3.86	2.85	1.57	1.73
Quick Ratio	2.51	2.51	2.61	2.86	3.16	3.79
Current Ratio	2.76	2.76	2.78	3.08	3.51	4.04
Return on Equity (ROE)	55.79%	73.28%	362.29%	232.40%	-526.14%	-106.31%
Return on Assets (ROA)	10.58%	10.58%	-3.23%	-7.77%	-21.92%	-20.12%
Return on Invested Capital (ROIC)	63.85%	63.85%	-20.29%	-43.01%	-108.72%	-76.10%
Return on Capital Employed (ROCE)	15.31%	15.31%	-5.98%	-10.01%	-27.42%	-24.57%
Earnings Yield	0.77%	0.59%	-0.93%	-1.84%	-3.91%	-4.25%
FCF Yield	1.15%	0.88%	-0.14%	0.17%	-2.08%	-3.52%
Buyback Yield / Dilution	-5.51%	-5.51%	-2.20%	-2.64%	-2.73%	-3.01%
Total Shareholder Return	-5.51%	-5.51%	-2.20%	-2.64%	-2.73%	-3.01%

Updated Feb 12, 2026. Data Source: Fiscal.ai. Standard template. Financial Sources.

SEC Filings: 10-K · 10-Q