Aptevo Therapeutics Inc. (APVO)

NASDAQ: APVO · Real-Time Price · USD
4.950
0.00 (0.00%)
At close: May 22, 2026, 4:00 PM EDT
4.590
-0.360 (-7.27%)
Pre-market: May 26, 2026, 4:52 AM EDT
Market Cap5.85M +1,069.9%
Revenue (ttm)n/a
Net Income-26.16M
EPS-45.13
Shares Out 1.18M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume26,645
Open5.100
Previous Close4.950
Day's Range4.750 - 5.220
52-Week Range3.800 - 235.978
Beta1.64
AnalystsStrong Buy
Price Target21.00 (+324.24%)
Earnings DateMay 13, 2026

About APVO

Aptevo Therapeutics Inc., a clinical-stage research and development biotechnology company, focuses on developing immunotherapeutic candidates for the treatment of various forms of cancer in the United States. The company develops its products using ADAPTIR and ADAPTIR-FLEX platforms to generate monospecific, bispecific, and multi-specific antibody candidates capable of enhancing the human immune system against cancer cells. Its lead clinical blood cancer candidate is mipletamig that is in Phase 1b/2 clinical trial for the treatment of acute mye... [Read more]

Industry Biotechnology
Sector Healthcare
Founded 2016
Employees 33
Stock Exchange NASDAQ
Ticker Symbol APVO
Full Company Profile

Financial Performance

Financial Statements

Analyst Summary

According to one analyst, the rating for APVO stock is "Strong Buy" and the 12-month stock price target is $21.0.

Price Target
$21.0
(324.24% upside)
Analyst Consensus: Strong Buy

News

Aptevo Therapeutics reports Q1 cash and cash equivalents $14.5M

“Aptevo is entering a defining period as a company, supported by growing clinical momentum, a committed leadership team, and a pipeline with the potential to create significant long-term value,” said…

12 days ago - TheFly

Aptevo Therapeutics Provides a 1Q26 Business Update; RAINIER on Track for 2026 Completion and Phase 2 Dose Selection

Mipletamig continues to perform, delivers 87% clinical benefit and 81% remission in frontline AML, with no CRS in frontline patients Executive leadership transition complete. Jeff Lamothe appointed CE...

12 days ago - Accesswire

Aptevo reports 87% clinical benefit in frontline AML patients in RAINIER trial

Aptevo Therapeutics (APVO) reported new clinical results from its RAINIER frontline acute myeloid leukemia trial. The company is on track to complete the Phase 1b dose-optimization trial and select th...

19 days ago - TheFly

Aptevo Reports 87% Clinical Benefit and 81% Remission in 31 Evaluable Frontline AML Patients Through Cohort 5, Substantially Outperforming Benchmark; RAINIER on Track for 2026 Completion and Phase 2 Dose Selection

Program Enters Final Stage of Dose Optimization Data Continue to Demonstrate Strong Clinical Activity and Favorable Safety Across an Expanding Frontline Dataset SEATTLE, WA / ACCESS Newswire / May 6, ...

19 days ago - Accesswire

Aptevo Therapeutics reports FY25 EPS ($87.27) vs. ($31,460.23) last year

“2025 was a year of meaningful progress across our clinical programs, pipeline strategy and capital position,” said Marvin White, CEO. “Most importantly, recently reported mipletamig data continue to ...

2 months ago - TheFly

Aptevo Therapeutics sees cash runway into 4Q26

Aptevo ended 2025 with $21.6 million in cash and cash equivalents, compared with $8.7 million at December 31, 2024, and expects current resources to support operations into the fourth quarter…

2 months ago - TheFly

Aptevo Provides State of the Business Report and 2025 Financial Results

Latest mipletamig data delivers 86% clinical benefit rate with no cytokine release syndrome in 28 frontline AML patients, supporting its potential to enhance standard-of-care combination therapy Compa...

2 months ago - Accesswire

Aptevo to Participate in March 2026 Conferences

SEATTLE, WA / ACCESS Newswire / March 19, 2026 / Aptevo Therapeutics Inc. (NASDAQ:APVO), a clinical-stage biotechnology company developing novel immune-oncology therapeutics based on its proprietary A...

2 months ago - Accesswire

Aptevo Therapeutics announces interim data for mipletamig combination

Aptevo Therapeutics (APVO) announced new interim data for mipletamig in combination with venetoclax and azacitidine in newly diagnosed acute myeloid leukemia patients who are either elderly or unfit f...

2 months ago - TheFly

Mipletamig Delivers Compelling 86% Clinical Benefit Rate and No CRS as Evaluable AML Patient Data increases by Nearly 50%

Frontline patient outcomes are making the case for mipletamig to enhance standard-of-care therapy alongside venetoclax + azacitidine SEATTLE, WA / ACCESS Newswire / March 10, 2026 / Aptevo Therapeutic...

2 months ago - Accesswire

Aptevo Therapeutics CEO Marvin White to retire, assume Executive Chair role

Aptevo Therapeutics (APVO) announced executive leadership transitions to support the Company’s continued execution, drive achievement of long-term strategic objectives, and next phase of growth. Effec...

3 months ago - TheFly

Aptevo Announces Executive Leadership Transitions to Support Next Phase of Growth

Clinical progress, pipeline expansion, and operational momentum underpin leadership continuity as the Company advances into 2026 and beyond SEATTLE, WA / ACCESS Newswire / February 3, 2026 / Aptevo Th...

3 months ago - Accesswire

Aptevo Therapeutics files to sell 7.075M shares of common stock for holders

16:08 EST Aptevo Therapeutics (APVO) files to sell 7.075M shares of common stock for holders

4 months ago - TheFly

Aptevo Therapeutics secures $60M equity line of credit

Aptevo Therapeutics (APVO) entered into a $60M equity line of credit agreement with Yorkville Advisors Global, LP, strengthening the Company’s financial flexibility as it continues to advance its clin...

4 months ago - TheFly

Aptevo Therapeutics Secures $60 Million Equity Line of Credit to Support Multispecific Portfolio Advancement, Increase Strategic Optionality

Together with cash on hand, the fully leveraged facility extends Aptevo's funding runway into 2029, enabling achievement of key clinical and preclinical milestones SEATTLE, WA / ACCESS Newswire / Janu...

4 months ago - Accesswire

Aptevo Therapeutics trading halted, news pending

19:50 EST Aptevo Therapeutics (APVO) trading halted, news pending

5 months ago - TheFly

Aptevo Therapeutics Announces 1-for-18 Reverse Stock Split

SEATTLE, WA / ACCESS Newswire / December 26, 2025 / Aptevo Therapeutics Inc. (NASDAQ:APVO), a clinical-stage biotechnology company focused on developing novel immune-oncology therapeutics based on its...

5 months ago - Accesswire

Aptevo Therapeutics presents preliminary results from Phase 1b/2 RAINIER study

Aptevo Therapeutics (APVO) presented preliminary results from its ongoing Phase 1b/2 RAINIER study evaluating mipletamig, a CD123 x CD3 bispecific molecule, in combination with azacitidine and venetoc...

5 months ago - TheFly

Aptevo Therapeutics Highlights Compelling Safety and Strong Remission Rates for Mipletamig in Frontline AML at ASH 2025

100% of patients in Cohorts 1-3 remain free of cytokine release syndrome CRIS-7-derived CD3 design underpins a controlled T-cell response, supporting the differentiated safety profile, combinability w...

5 months ago - Accesswire

Aptevo Therapeutics debuts trispecific antibody candidate APVO451

Aptevo Therapeutics (APVO) announced the first presentation of preclinical data for its new trispecific antibody, APVO451, at the Society for Immunotherapy of Cancer Annual Meeting on Saturday, Novemb...

7 months ago - TheFly

Aptevo Debuts First Trispecific Antibody Candidate, APVO451, with Preclinical Data Demonstrating Immune Activation in Hard-to-Treat Solid Tumors

First data on Aptevo's new molecule presented at the Society for Immunotherapy of Cancer (SITC) Annual Meeting SEATTLE, WASHINGTON / ACCESS Newswire / November 10, 2025 / Aptevo Therapeutics ("Aptevo"...

7 months ago - Accesswire

Aptevo Therapeutics management to meet virtually with Roth Capital

Virtual Meeting to be held on November 13-14 hosted by Roth Capital.

7 months ago - TheFly

Aptevo Therapeutics reports Q3 EPS ($2.23) vs. ($357.86) last year

“We continue to make disciplined progress across both our clinical and research programs,” said Marvin White, President and Chief Executive Officer of Aptevo. “The Cohort 3 results reinforce mipletami...

7 months ago - TheFly

Aptevo Therapeutics sees cash runway into 4Q26

Aptevo had cash and cash equivalents as of September 30, 2025, totaling $21.1 million. During the third quarter of 2025, the Company raised $18.7 million, net under the Company’s Standy…

7 months ago - TheFly

Aptevo Therapeutics reports Q3 EPS (23c) vs. ($357.86) last year

“We continue to make disciplined progress across both our clinical and research programs,” said Marvin White, President and Chief Executive Officer of Aptevo. “The Cohort 3 results reinforce mipletami...

7 months ago - TheFly