Bicycle Therapeutics plc (BCYC)

NASDAQ: BCYC · Real-Time Price · USD
4.450
-0.220 (-4.71%)
At close: May 15, 2026, 4:00 PM EDT
4.440
-0.010 (-0.22%)
After-hours: May 15, 2026, 7:43 PM EDT
Market Cap310.20M -47.7%
Revenue (ttm)63.50M +146.9%
Net Income-219.02M
EPS-3.16
Shares Out 69.71M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume377,131
Open4.610
Previous Close4.670
Day's Range4.414 - 4.660
52-Week Range4.240 - 9.360
Beta1.56
AnalystsBuy
Price Target13.75 (+208.99%)
Earnings DateApr 30, 2026

About BCYC

Bicycle Therapeutics plc, a clinical-stage pharmaceutical company, develops a class of medicines for diseases that are underserved by existing therapeutics in the United States and the United Kingdom. The company’s products pipeline include zelenectide pevedotin, a bicycle toxin conjugate (BTC), which is in phase II clinical trials for the treatment of high nectin-4 expressing tumors; nuzefatide pevedotin (EphA2), a BTC that is in phase I/II clinical trials to treat Ephrin type A receptor 2 expressing tumor; BT7480, a Bicycle tumor-targeted imm... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date May 23, 2019
Employees 288
Stock Exchange NASDAQ
Ticker Symbol BCYC
Full Company Profile

Financial Performance

In 2025, Bicycle Therapeutics's revenue was $72.59 million, an increase of 105.77% compared to the previous year's $35.28 million. Losses were -$218.96 million, 29.5% more than in 2024.

Financial Statements

Analyst Summary

According to 8 analysts, the average rating for BCYC stock is "Buy." The 12-month stock price target is $13.75, which is an increase of 208.99% from the latest price.

Price Target
$13.75
(208.99% upside)
Analyst Consensus: Buy
Stock Forecasts

News

Bicycle Therapeutics price target lowered to $12 from $13 at Jefferies

Jefferies analyst Maury Raycroft lowered the firm’s price target on Bicycle Therapeutics (BCYC) to $12 from $13 and keeps a Buy rating on the shares. Bicycle’s update was broadly incremental…

15 days ago - TheFly

Bicycle Therapeutics reports Q1 EPS (87c), consensus (65c)

Reports Q1 revenue $887k, consensus $7.5M. “The data we reported in the first quarter continues to provide further validation of the potential of our Bicycle technology to deliver oncology therapeutic...

15 days ago - TheFly

Bicycle Therapeutics Reports Recent Business Progress and First Quarter 2026 Financial Results

CAMBRIDGE, England & BOSTON--(BUSINESS WIRE)--Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyc...

15 days ago - Business Wire

Bicycle Therapeutics Announces Oral and Poster Presentations at the 2026 ASCO Annual Meeting

CAMBRIDGE, England & BOSTON--(BUSINESS WIRE)--Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyc...

24 days ago - Business Wire

Bicycle Therapeutics announces updates from EphA2 pipeline at AACR meeting

Bicycle Therapeutics (BCYC) announced updates from its EphA2 pipeline at the American Association for Cancer Research Annual Meeting 2026. Nuzefatide pevedotin, formerly BT5528, a potentially first-in...

25 days ago - TheFly

Bicycle Therapeutics Provides Update on Nuzefatide Pevedotin and EphA2 Pipeline at the AACR Annual Meeting 2026

CAMBRIDGE, England & BOSTON--(BUSINESS WIRE)--Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyc...

25 days ago - Business Wire

Bicycle Therapeutics price target lowered to $12 from $13 at Morgan Stanley

Morgan Stanley lowered the firm’s price target on Bicycle Therapeutics (BCYC) to $12 from $13 and keeps an Equal Weight rating on the shares. The firm update its model to…

5 weeks ago - TheFly

Bicycle Therapeutics price target lowered to $7 from $11 at RBC Capital

RBC Capital lowered the firm’s price target on Bicycle Therapeutics (BCYC) to $7 from $11 and keeps a Sector Perform rating on the shares. The pivot away from zele toward…

2 months ago - TheFly

Bicycle Therapeutics price target lowered to $36 from $44 at Oppenheimer

Oppenheimer analyst Jay Olson lowered the firm’s price target on Bicycle Therapeutics (BCYC) to $36 from $44 and keeps an Outperform rating on the shares. Along with reporting its Q4…

2 months ago - TheFly

Bicycle Therapeutics Announces Oral and Poster Presentations at the AACR Annual Meeting 2026

CAMBRIDGE, England & BOSTON--(BUSINESS WIRE)--Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyc...

2 months ago - Business Wire

Bicycle Therapeutics price target lowered to $8 from $12 at Citizens

Citizens analyst Reni Benjamin lowered the firm’s price target on Bicycle Therapeutics (BCYC) to $8 from $12 and keeps an Outperform rating on the shares. Bicycle reported Q4 earnings alongside…

2 months ago - TheFly

Bicycle Therapeutics price target lowered to $8 from $10 at Truist

Truist analyst Gregory Renza lowered the firm’s price target on Bicycle Therapeutics (BCYC) to $8 from $10 and keeps a Hold rating on the shares. Bicycle Therapeutics announced a “no-go”…

2 months ago - TheFly

Bicycle Therapeutics reports Q4 EPS (29c), consensus (95c)

Reports Q4 revenue $47.96M, consensus $7.08M. The increases in collaboration revenue of $44.3M and $37.3M for the three months and year ended December 31, 2025, respectively, were primarily due to…

2 months ago - TheFly

Bicycle Therapeutics Reports Recent Business Progress and Fourth Quarter and Full Year 2025 Financial Results

CAMBRIDGE, England & BOSTON--(BUSINESS WIRE)--Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyc...

2 months ago - Business Wire

Bicycle Therapeutics CFO Alethia Young steps down, Travis Thompson succeeds

Bicycle Therapeutics (BCYC) announced leadership transitions. Travis Thompson, who began at Bicycle in April 2018 and most recently served as Bicycle’s senior vice president and chief accounting offic...

3 months ago - TheFly

Bicycle Therapeutics CMO Eric Westin retires, Michael Method succeeds

Michael Method who began at Bicycle in June 2025 and most recently served as Bicycle’s senior vice president, clinical development, has been promoted to chief medical officer, or CMO, overseeing…

3 months ago - TheFly

Bicycle Therapeutics names Michael Skynner chief scientific officer

Michael Skynner, who began at Bicycle in January 2016 and most recently served as Bicycle’s chief technology officer, will now serve as chief scientific officer. Skynner will oversee scientific discov...

3 months ago - TheFly

Bicycle Therapeutics Announces Leadership Transitions for Next Phase of Innovation Across Oncology Pipeline

CAMBRIDGE, England & BOSTON--(BUSINESS WIRE)--Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyc...

3 months ago - Business Wire

Bicycle Therapeutics Highlights 2025 Accomplishments and Strategic Priorities for 2026

CAMBRIDGE, England & BOSTON--(BUSINESS WIRE)--Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyc...

4 months ago - Business Wire

Bicycle signs 15-year uranium contract with UK Nuclear Decommissioning Authority

Bicycle Therapeutics (BCYC) announced it has entered into a 15-year contract including an option to renew with the UK Nuclear Decommissioning Authority for access to up to 400 tons of…

5 months ago - TheFly

Bicycle Therapeutics Establishes Multiple Strategic Partnerships to Create End-to-End Supply Chain to Support its Wholly Owned Radiopharmaceutical Pipeline

CAMBRIDGE, England & BOSTON--(BUSINESS WIRE)--Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyc...

5 months ago - Business Wire

Bicycle Therapeutics initiated with a Hold at Truist

Truist initiated coverage of Bicycle Therapeutics (BCYC) with a Hold rating and $10 price target The time to market and ultimate market potential remains uncertain for Zele, pending further visibility...

6 months ago - TheFly

Bicycle Therapeutics Transcript: Jefferies London Healthcare Conference 2025

The session highlighted a differentiated bicyclic peptide platform with a focus on toxin and radio conjugates, notably zelenectide pevedotin for bladder cancer, aiming for superior safety and efficacy. Key milestones include pivotal trial data in Q1 2026 and a strong cash runway into 2028.

6 months ago - Transcripts

Bicycle Therapeutics to Participate in the Jefferies London Healthcare Conference

CAMBRIDGE, England & BOSTON--(BUSINESS WIRE)--Bicycle Therapeutics plc (NASDAQ: BCYC), a pharmaceutical company pioneering a new and differentiated class of therapeutics based on its proprietary bicyc...

6 months ago - Business Wire

Bicycle Therapeutics price target raised to $12 from $10 at Citizens JMP

Citizens JMP analyst Reni Benjamin raised the firm’s price target on Bicycle Therapeutics (BCYC) to $12 from $10 and keeps an Outperform rating on the shares. Bicycle reported Q3 financial…

7 months ago - TheFly