Company Description
Bicycle Therapeutics plc, a clinical-stage pharmaceutical company, develops a class of medicines for diseases that are underserved by existing therapeutics in the United States and the United Kingdom.
The company’s products pipeline include zelenectide pevedotin, a bicycle toxin conjugate (BTC), which is in phase II clinical trials for the treatment of high nectin-4 expressing tumors; nuzefatide pevedotin (EphA2), a BTC that is in phase I/II clinical trials to treat Ephrin type A receptor 2 expressing tumor; BT7480, a Bicycle tumor-targeted immune cell agonist molecule, which is in phase I/II targeting nectin-4 and agonizing CD137; and BT1702, a theranostic BRC molecule targeting MT1-MMP for which IND-enabling activities are ongoing.
In addition, it develops Novel CNS targets, which is in preclinical trial targeting CNS disease; Novel neuromuscular targets, which is in preclinical trial targeting neuromuscular disease; and programs that are in preclinical trial targeting radiopharmaceutical.
Further, the company collaborates with biopharmaceutical companies and organizations to develop programs in therapeutic areas.
It has collaboration and license agreement with Bayer Consumer Care AG; Novartis Pharma AG; Ionis Pharmaceuticals, Inc.; Genentech, Inc; and AstraZeneca AB.
Bicycle Therapeutics plc was incorporated in 2009 and is headquartered in Cambridge, the United Kingdom.
| Country | United Kingdom |
| Founded | 2009 |
| IPO Date | May 23, 2019 |
| Industry | Biotechnology |
| Sector | Healthcare |
| Employees | 288 |
| CEO | Kevin Lee |
Contact Details
Address: Portway Building, Blocks A & B Cambridge, CB21 6GS United Kingdom | |
| Phone | 44 1223 261 503 |
| Website | bicycletherapeutics.com |
Stock Details
| Ticker Symbol | BCYC |
| Exchange | NASDAQ |
| Fiscal Year | January - December |
| Reporting Currency | USD |
| IPO Price | $14.00 |
| CIK Code | 1761612 |
| CUSIP Number | 088786108 |
| ISIN Number | US0887861088 |
| SIC Code | 2834 |
Key Executives
| Name | Position |
|---|---|
| Dr. Kevin Lee M.B.A., Ph.D. | Chief Executive Officer and Executive Director |
| Alistair Milnes | Chief Corporate Development Officer |
| Prof. Michael Charles-Ferguson Hannay | Chief Product and Supply Chain Officer |
| Dr. Christian Heinis | Scientific Founder |
| Travis Thompson | Chief Financial Officer |
| Jennifer Perry Pharm.D. | Chief Operating Officer |
| Dr. Michael Skynner B.sc. Ph.d., Ph.D. | Chief Scientific Officer |
| Stephanie Yao | Senior Vice President of Investor Relations and Corporate Communications |
| Zafar Qadir | Chief Legal Officer and General Counsel |
| Dr. Gillian Langford Ph.D. | Head of Clinical and Project Management |
Latest SEC Filings
| Date | Type | Title |
|---|---|---|
| Mar 17, 2026 | S-8 | Securities to be offered to employees in employee benefit plans |
| Mar 17, 2026 | 10-K | Annual Report |
| Mar 17, 2026 | 8-K | Current Report |
| Mar 4, 2026 | SCHEDULE 13G/A | Filing |
| Mar 3, 2026 | SCHEDULE 13G | Filing |
| Mar 3, 2026 | SCHEDULE 13G/A | Filing |
| Mar 3, 2026 | SCHEDULE 13G/A | Filing |
| Feb 18, 2026 | SCHEDULE 13G | Filing |
| Feb 11, 2026 | SCHEDULE 13G/A | Filing |
| Feb 3, 2026 | 8-K | Current Report |