Cardinal Health, Inc. (CAH)
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Morgan Stanley 22nd Annual Global Healthcare Conference

Sep 5, 2024

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Hi, good morning, everyone. My name is Erin Wright. I'm the Healthcare Services Analyst at Morgan Stanley, and we're happy to have with us this morning, Cardinal Health, in a very kind of dynamic morning for drug distribution. And with us today, we have Aaron Alt, CFO, as well as Matt Sims, who heads up the IR effort at Cardinal. For important disclosures, please see the Morgan Stanley Research Disclosure website at www.morganstanley.com/researchdisclosures. If you do have any questions, please reach out to your Morgan Stanley sales representative. And with that disclosure, I'll hand it over to Matt for more disclosures.

Matt Sims
VP, Head of Investor Relations and Enterprise FP&A, Cardinal Health

Perfect. Well, thanks for hosting us today, Erin. It's great to be here. As you mentioned, just some quick housekeeping before we get started. So we will be making forward-looking statements today, which are subject to risks and uncertainties that could cause our actual results to differ materially from those projected or implied. For a description of these factors, please review our SEC filings, which can be found on our investor relations website at ir.cardinalhealth.com.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Okay, great. So we'll get started with some Q&A. This is kind of a bigger picture question on the long-term view and vision, but you're targeting 4%-6% Pharma and Specialty Solutions EBIT growth over the longer term. I guess, more broadly, are what are some of those key underlying segment drivers? What's sustainable right now in terms of the strength that we've been seeing in underlying utilization trends and just underlying performance across that core pharma business?

Aaron Alt
CFO, Cardinal Health

Sure. Thank you for the question, and before I go there, just, thank you for having us, both on behalf of myself and our entire team, and certainly Jason Hollar, our leader. We are entering our new fiscal year. We are a month and a half into it, coming off of a strong fiscal 2024 and a strong Q4, which gave us momentum coming into the year. And indeed, we have a fair bit of confidence relative to the business that we're helping to transform and drive and the guide that we provided, which I know, we're about to touch on. And so for us, it's about staying consistent with the strategy that's already out there and executing every day against the operational improvements. As you called out, we guide pharma 4%-6% long-term growth.

We adjusted that for this year, given a large contract non-renewal, which I think we're all aware of, to 1%-3% growth. And so what should be notable is we're able to still guide profit up, notwithstanding a you know large contract non-renewal. And the reason we're able to do that is the strength and resiliency of the portfolio, indeed, the underlying business that we're building. There are a couple of things that are true. Our core pharma business is in a good position. We expect that business to grow low single digits you know this year. We also expect specialty to play a continuing contributor to the business. Before I can really describe the profit drivers further, I need to go back and touch on revenue for a second as well.

Revenue is down, will be down for the year in the pharma business, 4-6%, but if you take out that large customer non-renewal, it's actually up 15-18%, right? What that should tell you is that key parts of our portfolio are growing rapidly. There's an underlying organic growth revenue assumption within the rest of the portfolio of 10%, pharma portfolio of 10%, and there's a guide of $10 billion of new customer and expanded business with existing customers beyond just growing the business that we have.

You know, that certainly contributes to our profit growth, and while we don't comment on the margin profile of new customers, I will observe that we have commented on the margin profile of customers who are no longer with us being quite modest. And so it is certainly helping us that we're growing, and we're growing with more sustainable margin customers as we carry forward. Now, stepping back on the pharma business as well, what else is going on? Why do we have the confidence to give the guide we did on the 1%-3% growth? The first is, we are seeing, and we expect a strong pharmaceutical demand environment, and so we're operating in a stable environment, a strong environment, you know, in that way.

It's also the case that we're assuming within our core pharma business, that we have what we like to refer to as consistent market dynamics in our generic portfolio. We operate at scale, we have best access, we have low cost. We're able to manage generics as a portfolio, and so we look at consistent market dynamics, meaning that we can manage the profitability so long as we have good volume, and we anticipate that as part of our, you know, guide as well.

And then more broadly, as we think about the specialty part of the portfolio, we've been investing in that part of the portfolio now for some time, and again, notwithstanding the contract non-renewal, we expect to grow our specialty portfolio, which is growing, as I said, at a double digit margin perspective in an attractive way as we carry forward.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Okay. And then just because it was out this morning from Cencora, you embedded the dynamic in terms of the year over year, year comp from a COVID perspective, but COVID wasn't as meaningful from a vaccine perspective for you, right?

Aaron Alt
CFO, Cardinal Health

Yeah, we have embedded our expectations on COVID into the guide that we provided a couple of weeks ago. It's a modest impact for us. It probably touches Q2 more than any other part of the year, given last year. But we have nothing new to announce today around COVID or any other matters.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

And I think it's impressive in terms of what you're seeing in terms of the offsets from Optum. And is there any surprises, though, with the Optum roll-off in terms of stranded cost or anything like that to call out?

Aaron Alt
CFO, Cardinal Health

Mm-hmm.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

In terms of some of those offsets, whether it's Elevance or otherwise, Publix, another new one for you, you know, how are those ramping in terms of those relationships?

Aaron Alt
CFO, Cardinal Health

Yeah, for those of you who are relatively new to the story, or indeed, for those of you that are not, let me give you a little bit of a primer on this. When the contract non-renewal was first, when it was decided, we were ready for it. We had been doing scenario planning up until the last minute as to what will we do, and so we walked into that final decision by them prepared for where this would go. So we were able to quickly, you know, pivot and pursue three things. First, we've been working on additional customers, which will be largely. Publix is certainly one of them. The additional business with BioPlus is another one. That's a expansion of existing business.

That is largely back-half loaded for us from a year perspective. We also had been working on how do we optimize our cost portfolio? We were very pleased with the SG&A delivery, the optimization that happened within fiscal 2024, and we took aggressive action and plans while supporting our customers to set us up for success in 2025. That will ramp over the year as well, but those actions are already in flight, and many of them have been acted. Then, of course, we have the Specialty Networks acquisition, which we did in the back half of last year, which is obviously in specialty, where, you know, that is a nice profit contributor.

It was in Q4, and that profit grows over the course of, you know, this year as well. What? Those were things we talked about when we gave our initial guide. What I'm here today to tell you is that, you know, we had a plan, we're executing against it, we've got the momentum, we've got the confidence we can hit that plan. And indeed, you saw as you saw in our Q4 earnings call, when we raised the guide from at least 1%-3%, you know, that's a signal of the confidence we have in executing against it, but also that we're leaving no stone unturned to ensure that we're both supporting the customer and able to optimize our overall, you know, margin profile.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Okay, and then this is kind of a broader question just on the pharmacy landscape in general, but there's a lot going on. You have an independent pharmacy channel that's not new, it's under pressure, but Rite Aid coming out of bankruptcy, you have Walgreens in commotion there. But you do seem to be aligning yourself, like you're saying, in terms of with growing customers, and customers that seem to be better positioned. I guess, how are you navigating this, though-

Aaron Alt
CFO, Cardinal Health

Mm-hmm.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

and how do you kind of play a role in that?

Aaron Alt
CFO, Cardinal Health

Yeah, a couple thoughts. One, we like to talk about our strategy is to win with the winners, and certainly, we have a long-standing partnership with CVS that we continue to reinforce every day. We may talk about some elements of that, you know, later today. We also have a very strong presence with retail independents, right? Our view is that we are going to stay focused on the key customers and partners that we have. We continue every day to think about how can we better support them from a core distribution services perspective, from other services within the portfolio, particularly with respect to the retail independents.

We believe we're well-situated to both maintain and grow our business with those customers, while adding in ways which are not at all challenging for our existing customers, great new customers like Publix, like expanding the business with you know, BioPlus, Elevance, et cetera.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

And then in terms of the core, base pharma business, the drug pricing environment, you mentioned kind of generics and efficiencies there. But, can you talk a little bit about what you're seeing from a drug pricing perspective, and then also just the impact from IRA and general visibility on the drug pricing environment?

Aaron Alt
CFO, Cardinal Health

Sure. We don't have a lot new to say about the drug pricing environment, and there are occasional news stories about what the latest thing coming down the pike. But as we think about our generics portfolio, one of the nice things about our business is because of our scale, because of our partnership with Red Oak with CVS, we do believe we have industry-leading access. We also believe we have industry-leading cost, and because of that, we're able to manage the portfolio. And so if there is a particular drug or class of drugs where there is a perception of you know, inflation or deflation, we're able to manage through that. We're focused on how do we continue to drive that volume and a strong prescription environment.

Within the branded side of the portfolio, of course, it is a fact that there is manufacturer inflation over the course of the year, and the signals we're reading is that the inflation, the branded inflation, will be generally consistent this year as it's been for the last, you know, several years. And so we're not expecting there to be a significant put or take in our portfolio, and our expectations are built into the guidance that we provided already. With respect to the IRA, you know, it's a complicated topic that the... A lot of the story is still to be written.

What we continue to come back to is, look, our role in this industry is to safely, securely, and efficiently ensure that ultimately, the patient can get the pharmaceuticals they need or the Medical supplies. And we will continue to bob and weave as we have, and our business model has evolved from time to time. But look, we're running a 1% margin business here, which is relatively capital intensive, and we'll need to be compensated for the services we're providing, and we believe the ecosystem in which we're operating understands that.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Okay, and then shifting to specialty, I guess, you know, Cardinal Specialty business has experienced robust growth. You're growing 14%, I think, CAGR over the past three years. How should we be thinking about the growth over the longer term? You've done some recent transactions there. Where is the focus in terms of the key drivers over the next few years?

Aaron Alt
CFO, Cardinal Health

Yeah, we're really pleased with the performance of our specialty portfolio. If you had a chance to read the transcript or listen to our Investor Day from a year ago, June, what you would have heard is Jason Hollar talking about how we are relentlessly focused on how do we improve our specialty focus, our specialty service, and indeed, our specialty penetration. It's a $36 billion business for us, or was a $36 billion business for us. Last year, it was growing at 14%. Last year, it grew at 14% from a CAGR perspective. And, you know, even with the contract non-renewal, which will take $3 billion or $4 billion, you know, off the revenue line there, right? We're still gonna grow it in fiscal 2025.

That's a sign of the resiliency and strength of, you know, that part of our portfolio. We are investing organically, both upstream and downstream, from how we are pursuing the specialty, you know, area. We are, as you, you've heard us talk, I imagine, about, you know, our organic efforts in, with Navista, further into the oncology space. Certainly, we did an inorganic acquisition recently called Specialty Networks, which gave us additional access, exposure, and importantly, technological capabilities in urology, gastroenterology, and rheumatology. We're excited to continue to leverage that as well. Much of where we are looking, both internally from an organic perspective and externally from an inorganic perspective, is how do we continue to reinforce that portfolio?

And so we're pleased with the results so far, but certainly always more to do.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Can you talk about Specialty Networks a little bit more in terms of what that kind of brings for you and other acquisitions you could do in the space?

Aaron Alt
CFO, Cardinal Health

Yeah, absolutely. I would describe it as, exposure, to therapeutic areas, certainly, team and talent, and then technology as well. As I referenced, Specialty Networks is a multi-specialty GPO plus. It's not an MSO organization. And what it did is it expanded our exposure in urology, gastroenterology, and rheumatology, areas where we already had a presence, but now we have an even stronger presence than we did before. Certainly expanded our customer, base, you know, across those areas as well.

From a team and talent perspective, what's been interesting is we like to laugh a little bit about it internally, where we bought the company, but we've given them the reins to key parts of our organization, where we liked what they were doing from an operation perspective, and they are already, not even yet two full quarters in, making us better because they are, not only are they continuing to accelerate the business they were running, they are making our core traditional business better as well by taking ownership of elements of what we were already doing, and so we're making the pie bigger, you know, as a result.

From a technology perspective, a key attribute of what we were buying is the PPS Analytics platform, which is reading 42 EMR systems across the providers that are ultimately receiving the pharmaceuticals distributed through the platform. The data is being aggregated, data is being sent to the ultimate drug manufacturers, but more importantly, the data and the specific therapeutic recommendations actually then going back down to the providers

And so, as you can imagine from a practitioner perspective, if you have a specific case in urology, rheumatology, or gastroenterology, and oh, by the way, increasingly oncology, if you have recommendations coming in of here, here's what other patients have experienced with specific sets of facts, that can be incredibly valuable insights and information to the provider, and so we're excited about that. Now, I alluded to it, we did not buy Specialty Networks to turn it into our oncology platform, but one of the pleasant findings post-transaction is just how much of an impact it is having on our technology build for oncology, on our practice approach, you know, for oncology, and so we see continued synergies beyond our original business case in that acquisition.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Speaking more of oncology, Navista, could you give us an update there? And how are you thinking about kind of community oncology in general and as an earnings driver for the quarter?

Aaron Alt
CFO, Cardinal Health

It's a great question. Indeed, there was a recent transaction in the space as well, for someone else. And what I would tell you is this: we laid out, last Investor Day, a differentiated strategy, for oncology. It wasn't be all, be everything to everyone. It was, how do we support the 2000+ individual oncologists who are fiercely independent, who want to remain independent, but who are looking around at the larger practices going: "Well, I want some of that. I want access to, better data services. I want better revenue cycle management, you know, capabilities. I want someone to manage the back office. I want better view, better access to, you know, drug discounts.

I want... They’re looking for that without having to give up their independence, and what we have been focused on for the last year is the foundational technology build, which we are making great progress on. We’ve been focused on building out the team, which we are largely done on from an experts who have done this before, who know oncology in their DNA. We’re really pleased with that. We’ve been focused on refining, defining, and rolling out our business model, which we have now done as well, and we’ve been focused on our customer pipeline, where the team is making great progress on that as well, and we’ll have more to say on that, you know, in coming quarters.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Okay, and then I think you commented a little bit about your relationship with CVS, and you have a recent JV there, too, Averon, if I'm saying-

Aaron Alt
CFO, Cardinal Health

Averon.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Correctly?

Aaron Alt
CFO, Cardinal Health

Yeah.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

And so can you talk a little bit about the rationale, the economics for you, the financial implications, you know, and how is this different maybe than, like, the purchasing consortium or other opportunities like that?

Aaron Alt
CFO, Cardinal Health

Yeah. Zooming out for a second, we have a long-term relationship with CVS, which covers a lot of ground. We distribute to their stores, we have the Red Oak generic sourcing agreement, a number of other arrangements, given the key partnerships between the two firms. And so we're really pleased with that relationship, and indeed, we continue to look for opportunities with CVS, about how can we do more together? Because it's in service of all of our customers, right? Not just, you know, the, the Cardinal, you know, CVS relationship. The latest announcement was the Averon partnership, which is biosimilars related, and not dissimilar from Red Oak, although they are completely different joint ventures. Averon is really focused on building the infrastructure for a...

How do we ensure best-in-class access and best-in-class costs relative to, you know, biosimilars, right? And we've started with a small number of, you know, biosimilar categories and biosimilars, and that will ramp up over time. But I wanna emphasize, it's in service. CVS is certainly servicing their own portfolio. We are servicing our entire portfolio through that joint venture, but it is completely distinct, you know, from Red Oak.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Okay. And then this is one more question on kind of pharma before we get into Medical, but this is more of a broader question of kind of pharma and pharmacy models, I guess. And I think there's some misconceptions about some of the DTC relationships that some of the pharma companies are launching-

like with Lilly and Pfizer more recently. I guess, how do you participate in those? Because I think you do, and or at least drug distributors do, and does this really change the model, meaningfully from

Aaron Alt
CFO, Cardinal Health

Yeah

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Your perspective?

Aaron Alt
CFO, Cardinal Health

It's always interesting picking the paper and reading what the next innovation is in the marketplace. And I say that somewhat glibly, but look, here, here's the point: underlying virtually all of these models, what you're reading about there, you typically have two things, a distributor in the background, and a pharmacy in the background. And so we or our peers, I won't claim to answer all the questions about all of them in this question, but you find a distributor like us, and you certainly find a pharmacy like our customers on underlying those environments. And so we support industry innovation overall. We are big fans of ensuring that ultimately, healthcare consumers have access to, you know, that which they need.

We want to be helpful in that way, and we believe we are helpful in that way as one of those background distributors, servicing background pharmacies, and part of where we're investing as well is, you heard me reference, you know, upstream and downstream investments. Really, part of where we're investing, we are investing as well, is to ensure that, you know, whether it's, you know, Lilly or Pfizer or others, who are making the changes, we want them coming to us because we have thought ahead. We have the capabilities they need to explore their own sets of innovation.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Okay, and I wanna make sure we get to Medical. I mean, it's been a big area in terms of focus for investors, in terms of the turnaround story. You know, you've laid out, you know, plans to reach that $300 million in EBIT by fiscal 2026 under the new segmentation.

Mm-hmm.

You know, how is that goal progressing, and what inning are we in terms of that transformation?

Matt Sims
VP, Head of Investor Relations and Enterprise FP&A, Cardinal Health

Yeah. Medical was a big win for us in fiscal 2024. As we entered the year, I think there may have been a little bit of skepticism that we could accomplish that which we had laid out relative to, you know, hitting the plan. And so we were very pleased on our Q4 earnings call to be able to describe the success that Steve Mason and his team had relative to driving almost a $240 million profit increase year over year from fiscal 2023 into fiscal 2024. It was driven by three consistent elements of our first Medical improvement plan, now our GMPD improvement plan, which is continuing to drive against inflation, you know, mitigation, continuing to drive the turnaround and growth of the Cardinal Health Brand, and then just simplification and cost optimization of the overall portfolio.

If you ask how they made the $240 million profit improvement, that's how, by executing against that, but there's more to do. So as part of our guide, we did guide fiscal 2025, which we're now a month into, at $175 million. That's consistent with our previous guidance. We guided fiscal 2026 to $300 million, and we are gonna keep doing what we've been doing, which is staying loyal to our strategy, benefiting from the continued opportunity on the inflation mitigation in 2025. Even though we got to run rate 100% at the end of 2024, we've still got more opportunity there in 2025. We're relentlessly focused on how do we drive the Cardinal Health brand growth.

It's a more profitable part of our portfolio, certainly, and then continued simplification and cost optimization everywhere we can.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Okay and then, you know, part of an element of, tied to that longer term growth target is a normalizing, kind of just general operating environment, and how would you characterize, I guess, you know, Medical growth, generally speaking, across the industry now, and then longer term, how do we think-

Matt Sims
VP, Head of Investor Relations and Enterprise FP&A, Cardinal Health

Yeah

Erin Wright
Healthcare Service Analyst, Morgan Stanley

about growth across that segment?

Matt Sims
VP, Head of Investor Relations and Enterprise FP&A, Cardinal Health

A part of our guide is an assumption of low double digit utilization growth over time. We've guided revenue up 3% to 5%, you know, for this coming year, and it's really us achieving that, and we have a couple of customer wins that are built into our guide as well, but that's how we're thinking about the overall environment.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Okay. And then, the profit opportunity associated with private label and the Cardinal brand products, I guess, it represents roughly a third, I think, of your profit today. Where does that go over time, and what needs to take place on that front?

Matt Sims
VP, Head of Investor Relations and Enterprise FP&A, Cardinal Health

Yeah, we haven't specifically guided the relative profitability, other than to comment that, as a, you know, owned brand or private label product, we have, it is a more profitable part of our portfolio, and that's why that's why it's one of the three pillars of our, you know, of our brand. So we need to continue to grow that. We've guided revenue growth for Cardinal Health Brand, also 3-5%, you know, in the year. But over the long term, what we've also said is that, from an overall GMPD improvement plan perspective, you know, that's an upward trending line over the three years, and so the impact of Cardinal Health Brand on our profitability will certainly grow over the year, but then also into 2026.

Part of why our Medical or GMPD, you know, guide is back half loaded again, is just the impact, the various puts and takes of, the three drivers of our business, and, Cardinal Health Brand is a good example of something that, you know, grows with time.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Okay. And then, sorry, excuse me. And then your cost mitigation efforts, you know, where does that stand now? I mean, you've made a lot of progress on that front, and you talked a little bit about that across Medical, but your ability to continue to implement those.

Matt Sims
VP, Head of Investor Relations and Enterprise FP&A, Cardinal Health

Mm-hmm. There continues to be opportunity everywhere we look from a cost optimization and simplification perspective. We recently announced, I hope we announced, a manufacturing change in our international portfolio, in the last week or so, which is, again, a good example of us continuing to assess where can we simplify our portfolio? Where can we do things more efficiently, either by optimizing our manufacturing network, because we are both a manufacturer and a distributor, or by optimizing our sourcing network, or by optimizing how we operate within our sales teams, or more broadly across the enterprise? Because it's not just about GMPD per say.

We are an enterprise, and we all have to contribute to the continued simplification and optimization, and we're watching every part of our team step up and assist the GMPD team in driving towards those profit goals.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

And then, any sort of update on freight trends, input cost, I guess, or to across your entire business, but, ability to pass those on to customers and also touch on tariffs as well?

Matt Sims
VP, Head of Investor Relations and Enterprise FP&A, Cardinal Health

Yeah. Why don't I take freight and you take tariffs? Okay, my voice is about to crack. The, there has been some concern around freight costs recently, and indeed, we have seen, as compared to a year ago, where we were getting to effective low points, we have been tracking some increases in freight. And the good news is that much of what we have been seeing, even before the start to move the other direction, was already built into our guidance. And so we had already planned for what we were seeing before we issued our final guidance. It was in the 175.

Now, it's also the case that as we've talked about inflation mitigation over time, our ability to both monitor, see it coming, and do something about it, either with our suppliers, through our negotiations, through the lanes we use, or being able to pass the costs on, has also been a, you know, key part of our effort, and we are much better positioned today than we were a year ago or two years ago to be able to manage that. So what I want you to take away on the freight is that we're watching it carefully. We believe it's built into our guidance. There hasn't been anything more material which would cause us to raise concern around that for GMPD for fiscal 2025 yet. You wanna hit tariffs?

Aaron Alt
CFO, Cardinal Health

Yeah. So on tariffs, the good news is our exposure to China is fairly modest, and so we do no self-manufacturing in the country. We only source less than 10% of our Cardinal Health Brand revenue from China. And so, as Aaron indicated, we have a highly diversified global supply chain that includes the Central America region. We have some domestic manufacturing capabilities, and we did touch on our Q4 call that syringes is an example of a category where there is some industry-wide disruption, that we have the ability to domestically manufacture that, and so we're making some investments to expand those capabilities. And so the point you should take away is that we're highly diversified and we're managing through it.

Matt Sims
VP, Head of Investor Relations and Enterprise FP&A, Cardinal Health

And that's a great point. And, you should take away that we are investing for the long term in the business about how do we continue to optimize the efficiency, of that business by doing the overall network analysis.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Okay. And then in terms of this other segment as well, you've said you're committed to nuclear, for instance. I guess, can you talk about where your focus is, though, within the other segment? Is it on nuclear? Is it the at-home segment? Is it all of the above? And where does that kind of go over time as we think about?

Matt Sims
VP, Head of Investor Relations and Enterprise FP&A, Cardinal Health

Yeah. We are very excited about, you know, that which we call other, and we wouldn't call it other if we had another choice, but the accountants made me do it. We have three businesses that roll up into other from a financial perspective. It's our nuclear precision health business, it is our, you know, at-home business, and it is our OptiFreight business. They are very different businesses from the rest of our portfolio and indeed very different businesses from each other. Part of our change this past January was to recognize the revenue and profit growth opportunities those three smaller businesses present to us, and so, we are doubling down on those businesses. That each of them now report directly to Jason Hollar, our CEO.

With the direct line to the CEO also comes direct accountability for hitting their plans and also comes access to additional resources. And so we are committed to investing in all three businesses, certainly from an organic capital perspective and expense perspective, to drive what we have guided to be, you know, significant growth within the portfolio. We've guided them to do 10% profit growth, as an other, within the year, but we have high expectations for all three of the businesses. Now, they will contribute in different ways at different times. As I said, we are investing in the technology. In OptiFreight, we've talked about we're investing in automation and new distribution points for the at-home business to drive the efficiency.

Within the nuclear business, we're investing in the Theranostics capabilities. You know, that business grew 20% for us in fiscal 2024. We have similar expectations, you know, as we carry forward. While the investment profiles of each of them is a little bit different, we are investing in all of them, and they will all continue to contribute to that 10% profit growth, you know, as we carry forward.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

In terms of investment, I guess most of that's organic, but what about inorganic investments and where the focus is now? Is it on the other segment and bolstering some of those capabilities, or what you're seeing in specialty? But where's the focus, and do you see kind of a robust M&A pipeline, or is it more focused on buybacks at this point?

Aaron Alt
CFO, Cardinal Health

Yeah. Boy, there's a lot to cover there. First, we think about investment through a disciplined capital allocation framework, where we first start with what. Given the strong cash flow we have had, and no doubt will have as we carry forward, first, where can we invest in the business organically? And we'll spend between $500 million and $550 million of capital investment in fiscal year 2025 in support of all of our businesses. And we have built some competition for resources internally within the business. After that, we protect the balance sheet, but there again, the team has made such great progress for the last couple of years.

We don't have to do much to protect the balance sheet and the business as it is because we are below our leverage ratios in support of our rating, indeed, with three positive outlook upgrades during fiscal year 2024. That then takes us to our baseline share repurchase, and we committed on our Q4 earnings call that we are gonna buy back $750 million of shares in fiscal 2025. That's a $250 million increase from, you know, prior year, but we have the cash and the cash flow to be able to do that, so we're committed to doing that. And that then leaves really to the point of your question, Well, what about M&A, right?

And we are certainly paying very careful attention to the marketplace, but we are even more aggressive in identifying from a strategy perspective of what do we want, what do we need, what can we go get versus waiting, you know, for the knock on the door and say, "Oh, by the way, something is for sale," by a strategic or a sponsor. And so our team is being very focused strategically on where can we grow our business inorganically. Now, that comes in two flavors. Until recently, that flavor was all about specialty all of the time. We were only going to invest M&A in specialty assets, and that's partly why the Specialty Networks acquisition was so attractive to us.

It was, we went and found the asset and got the deal done. Jason has broadened the aperture for us, our willingness to consider inorganic opportunities to also include the growth businesses. And so, for the right asset at the right time, but importantly, done in a very disciplined manner, we will consider inorganic investments in all of at-home, Optum, and nuclear. But I want to emphasize, it is while we've opened the aperture, our primary focus remains on specialty, and we will be very focused on any deals we do, being disciplined in how we go about doing them.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Okay, great, and then a shorter-term question for you in terms of how we think about the year and the quarterly progression. I guess anything to call out as we're modeling out kind of the next quarter, as well as kind of, I guess, subsequent-

quarters as we think about the-

Aaron Alt
CFO, Cardinal Health

Yeah, it's a great question. We got a lot going on. As you can probably tell from my comments, if you know our story, there's a lot of moving pieces underway. With respect to the pharma business, what we have guided is that we're working through the contract now, renewal. We've got these specific things we're doing to offset that profit impact. Much of that is more impactful in the back half of the year, and so we guided pharma for the first half of the year to be slightly down to flat. The second half of the year is where we'll see the growth. And we've also said that, you know, on an absolute dollar basis, Q3 historically has been and will be this year, our highest absolute dollar profit quarter within the pharma business.

Largely because that's the quarter in which most, not all, but most, manufacturers take their, you know, price increases. So that's where we see the impact of the inflation. On the med business, what we've said is that, like pharma, it's also more, back half loaded because we continue to execute against the Medical improvement plan, entirely consistent with how we, displayed our financials in fiscal year 2024. We were specific, though, when calling it out in fiscal. Sorry, the first quarter of fiscal 2025, because of, seasonality, Q4 to Q1, because of, you know, incurred manufacturing variances, which we typically incur those six or seven months after, and, end of the calendar year is when we start to see those. Q1 is down, you know, as a result of that.

Because of what Matt alluded to, some investments we're making to promote flexibility in our domestic supply chain in key areas. Q1 will be the lowest profit quarter for GMPD within the year, and we guided, you know, up to $20 million versus the revised $12 million for fiscal 2024 that we saw there. That's really the sense of the relative timing I can give you.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Okay, great. Thanks so much. I appreciate the time.

Aaron Alt
CFO, Cardinal Health

Of course.

Erin Wright
Healthcare Service Analyst, Morgan Stanley

Hope you have a great conference. Thank you.

Aaron Alt
CFO, Cardinal Health

Thank you. Thanks for having us.

Matt Sims
VP, Head of Investor Relations and Enterprise FP&A, Cardinal Health

Thanks, sir.

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