Company Description
CRISPR Therapeutics AG, a gene editing company, focuses on developing gene-based medicines for serious human diseases using its Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) platform.
Its CRISPR/Cas9 is a gene editing technology that allows for precise directed changes to genomic DNA.
The company has a portfolio of therapeutic programs across a range of disease areas, including hemoglobinopathies, immune-oncology and autoimmune, in vivo, and type 1 diabetes.
The company’s lead product candidate is CASGEVY, an ex vivo CRISPR/Cas9 gene-edited cell therapy for treating patients suffering from transfusion-dependent beta-thalassemia, severe sickle cell disease, and hemoglobinopathies in which a patient’s hematopoietic stem and progenitor cells are edited to produce high levels of fetal hemoglobin in red blood cells.
It also develops CAR T cell therapies, including CTX112 targeting CD19 and CTX131 targeting CD70 for oncology and autoimmunune indications; CTX310 and CTX320, in vivo gene editing to address the cardiovascular disease by disrupting the validated targets angiopoietin-like protein 3 and lipoprotein; and VCTX211, an allogeneic, gene-edited, hypoimmune stem cell-derived product candidate for the treatment of T1D.
It has strategic partnerships with Vertex Pharmaceuticals Incorporated, ViaCyte, Inc., Nkarta, Inc., and Capsida Biotherapeutics.
CRISPR Therapeutics AG was incorporated in 2013 and is headquartered in Zug, Switzerland.
| Country | Switzerland |
| Founded | 2013 |
| IPO Date | Oct 19, 2016 |
| Industry | Biotechnology |
| Sector | Healthcare |
| Employees | 407 |
| CEO | Samarth Kulkarni |
Contact Details
Address: Baarerstrasse 14 Zug, 6300 Switzerland | |
| Phone | 41 41 561 32 77 |
| Website | crisprtx.com |
Stock Details
| Ticker Symbol | CRSP |
| Exchange | NASDAQ |
| Fiscal Year | January - December |
| Reporting Currency | USD |
| CIK Code | 0001674416 |
| CUSIP Number | H17182108 |
| ISIN Number | CH0334081137 |
| Employer ID | 47-3173478 |
| SIC Code | 2836 |
Key Executives
| Name | Position |
|---|---|
| Dr. Samarth Kulkarni Ph.D. | Chief Executive Officer and Chairman |
| Dr. Raju Yashaswi Prasad Ph.D. | Chief Financial Officer |
| James R. Kasinger | General Counsel and Secretary |
| Shaun Foy | Founder |
| Dr. Emmanuelle Marie Charpentier | Co-Founder and Scientific Advisory Board Member |
| Dr. Craig C. Mello Ph.D. | Scientific Founder and Advisory Board Member |
| Dr. Chad A. Cowan Ph.D. | Scientific Founder |
| Dr. Matthew Porteus M.D., Ph.D. | Scientific Founder and Advisory Board Member |
| Dr. Daniel G. Anderson Ph.D. | Scientific Founder and Advisory Board Member |
| Julianne Bruno M.B.A. | Chief Operating Officer |
Latest SEC Filings
| Date | Type | Title |
|---|---|---|
| Aug 5, 2024 | S-3ASR | Automatic shelf registration statement of securities of well-known seasoned issuers |
| Aug 5, 2024 | S-8 | Securities to be offered to employees in employee benefit plans |
| Aug 5, 2024 | 10-Q | Quarterly Report |
| Aug 5, 2024 | 8-K | Current Report |
| Jun 3, 2024 | 8-K | Current Report |
| May 23, 2024 | 8-K | Current Report |
| May 8, 2024 | 10-Q | Quarterly Report |
| May 8, 2024 | 8-K | Current Report |
| Apr 15, 2024 | 144 | Filing |
| Apr 10, 2024 | SC 13G/A | [Amend] Statement of acquisition of beneficial ownership by individuals |