Castle Biosciences, Inc. (CSTL)

NASDAQ: CSTL · Real-Time Price · USD
20.26
-0.20 (-0.98%)
At close: Jun 17, 2026, 4:00 PM EDT
20.25
-0.01 (-0.05%)
After-hours: Jun 17, 2026, 4:10 PM EDT
Market Cap614.48M +30.8%
Revenue (ttm)339.92M -2.1%
Net Income-12.83M
EPS-0.44
Shares Out 30.33M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume310,437
Open20.68
Previous Close20.46
Day's Range19.86 - 20.71
52-Week Range14.59 - 44.28
Beta1.02
AnalystsStrong Buy
Price Target44.00 (+117.18%)
Earnings DateAug 3, 2026

About CSTL

Castle Biosciences, Inc., a molecular diagnostics company, provides test solutions for the diagnosis and treatment of dermatologic cancers, Barrett’s esophagus (BE), atopic dermatitis (AD), and uveal melanoma. The company offers DecisionDx-Melanoma, a risk stratification gene expression profile (GEP) test that predicts the likelihood of a positive sentinel lymph node and the risk of metastasis for patients with invasive cutaneous melanoma; TissueCypher, a risk stratification spatialomics test to predict future development of high-grade dysplasi... [Read more]

Sector Healthcare
IPO Date Jul 25, 2019
Employees 942
Stock Exchange NASDAQ
Ticker Symbol CSTL
Full Company Profile

Financial Performance

Financial Statements

Analyst Summary

According to 8 analysts, the average rating for CSTL stock is "Strong Buy." The 12-month stock price target is $44.0, which is an increase of 117.18% from the latest price.

Price Target
$44.0
(117.18% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Castle Biosciences’ TissueCypher Test surpasses 100,000 orders

Castle Biosciences (CSTL)’ TissueCypher Barrett’s Esophagus Test has surpassed 100,000 clinical test orders. TissueCypher is an AI-derived precision medicine test designed to predict a patient’s five-...

1 day ago - TheFly

First Patient Enrolled in New Study Assessing early prediction of flares in Atopic Dermatitis by Castle Biosciences in Collaboration with SciBase

STOCKHOLM, June 10, 2026 /PRNewswire/ -- SciBase Holding AB ("SciBase") (STO: SCIB), a leading developer of AI-powered skin health solutions, today announced that the first patient has been enrolled i...

7 days ago - PRNewsWire

Castle Biosciences Transcript: Jefferies Global Healthcare Conference 2026

Strong Q1 growth in core diagnostic tests led to raised 2026 revenue guidance and robust margins. New product launches and pipeline innovations target dermatology and GI markets, while legislative trends and clinical value support future reimbursement and adoption.

14 days ago - Transcripts

Castle Biosciences price target lowered to $35 from $50 at KeyBanc

KeyBanc lowered the firm’s price target on Castle Biosciences (CSTL) to $35 from $50 and keeps an Overweight rating on the shares.

19 days ago - TheFly

Castle Biosciences price target lowered to $40 from $50 at BTIG

BTIG lowered the firm’s price target on Castle Biosciences (CSTL) to $40 from $50 and keeps a Buy rating on the shares. The company delivered a solid 10% revenue beat…

5 weeks ago - TheFly

Castle Biosciences to Present at the 2026 Jefferies Global Healthcare Conference

FRIENDSWOOD, Texas, May 13, 2026 /PRNewswire/ -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that its executiv...

5 weeks ago - PRNewsWire

Castle Biosciences' AdvanceAD-Tx™ Test Receives 2026 MedTech Breakthrough Award for Genomics Innovation

This marks the fifth MedTech Breakthrough Award that Castle has earned for its innovative testing solutions FRIENDSWOOD, Texas, May 12, 2026 /PRNewswire/ -- Castle Biosciences, Inc. (Nasdaq: CSTL), a ...

5 weeks ago - PRNewsWire

Castle Biosciences reports Q1 EPS , consensus (49c)

Reports Q1 revenue $83.7M, consensus $79.23M. “The Castle Biosciences (CSTL) team delivered outstanding results to start 2026, delivering $83.7M in revenue,” said CEO Derek Maetzold. “Our momentum thi...

5 weeks ago - TheFly

Castle Biosciences raises 2026 revenue view to $345M-$355M from $340M-350M

2026 revenue consensus $345.73M.

5 weeks ago - TheFly

Castle Biosciences Earnings Call Transcript: Q1 2026

Q1 2026 saw strong revenue and test volume growth, with record months for core products and improved margins. Full-year guidance was raised, and new clinical data reinforced product value. Reimbursement clarity for AdvanceAD-Tx is expected by Q3, with material revenue anticipated in 2027–2028.

6 weeks ago - Transcripts

Castle Biosciences Slides: Q1 2026

Castle Biosciences has posted slides in relation to its Q1 2026 quarterly earnings report, which was published on May 6, 2026.

6 weeks ago - Filings

Castle Biosciences Quarterly report: Q1 2026

Castle Biosciences has published its Q1 2026 quarterly earnings report on May 6, 2026.

6 weeks ago - Filings

Castle Biosciences Earnings release: Q1 2026

Castle Biosciences released its Q1 2026 earnings on May 6, 2026, summarizing the period's financial results.

6 weeks ago - Filings

Castle Biosciences Reports First Quarter 2026 Results

Delivered Q1 2026 revenue of $83.7 million Q1 2026 total test reports for our core revenue drivers (DecisionDx ® -Melanoma, TissueCypher ®) increased 36% over Q1 2025 Raising full-year 2026 revenue g...

6 weeks ago - PRNewsWire

Castle Biosciences Supports Nationwide Patient Advocacy and Screening Initiatives to Celebrate Skin Cancer Awareness Month

Longstanding collaborations with AIM at Melanoma, the Melanoma Research Foundation, The Skin Cancer Foundation, IMPACT Melanoma and The Sun Bus continue to advance awareness and education throughout M...

6 weeks ago - PRNewsWire

New Data at DDW 2026 Show TissueCypher® Testing Improves Risk Stratification and Drives Risk-Aligned Management in Barrett's Esophagus

Clinical studies from Mayo Clinic researchers demonstrate the TissueCypher test provides improved risk stratification and influences risk-aligned surveillance decisions in clinical practice, with one ...

6 weeks ago - PRNewsWire

Castle Biosciences to Present New Data Demonstrating DecisionDx®-Melanoma's Ability to Identify Patients with Greater Risk of Recurrence and Poor Outcomes Within Early-Stage Melanoma at EADO and ACMS

Multi-center clinical and population-based data show that DecisionDx-Melanoma identifies biologically high-risk patients—including those with thin and early-stage disease—and provides recurrence risk ...

2 months ago - PRNewsWire

Castle Biosciences price target lowered to $40 from $50 at Canaccord

Canaccord analyst Kyle Mikson lowered the firm’s price target on Castle Biosciences (CSTL) to $40 from $50 and keeps a Buy rating on the shares. The firm updated its model…

2 months ago - TheFly

Castle Biosciences to Release First Quarter 2026 Financial Results and Host Webcast on Wednesday, May 6, 2026

FRIENDSWOOD, Texas, April 15, 2026 /PRNewswire/ -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that it will re...

2 months ago - PRNewsWire

Castle Biosciences Earns 2026 USA TODAY Top Workplaces Award for Fifth Consecutive Year

FRIENDSWOOD, Texas, April 10, 2026 /PRNewswire/ -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that it has rec...

2 months ago - PRNewsWire

Castle Biosciences Proxy statement: Proxy filing

Castle Biosciences filed a proxy statement on April 8, 2026, providing details for shareholder voting and corporate governance matters.

2 months ago - Filings

Castle Biosciences Proxy statement: Proxy filing

Castle Biosciences filed a proxy statement on April 8, 2026, providing details for shareholder voting and corporate governance matters.

2 months ago - Filings

Castle Biosciences to present new data from DecisionDx-Melanoma test at AAD

Castle Biosciences (CSTL) will present new data at the 2026 American Academy of Dermatology Annual Meeting, taking place March 27-31 in Denver, demonstrating that its DecisionDx-Melanoma test refines ...

2 months ago - TheFly

Castle Biosciences' DecisionDx®-Melanoma Test Significantly Improves Risk Prediction Within AJCC Stages to Support Personalized, Risk-Aligned Management of Cutaneous Melanoma, Data to Be Presented at AAD 2026

Data from 1,868 Surveillance, Epidemiology and End Results (SEER)-linked patients show DecisionDx-Melanoma significantly stratifies five-year melanoma-specific survival within American Joint Committee...

2 months ago - PRNewsWire

Castle Biosciences Transcript: Status update

The DECIDE study confirms DecisionDx-Melanoma's strong predictive value for sentinel lymph node positivity and recurrence risk, enabling precise risk stratification and safe de-escalation of care for low-risk melanoma patients. The test outperforms competing assays and is widely adopted in clinical practice, supporting its case for guideline inclusion.

3 months ago - Transcripts