Castle Biosciences, Inc. (CSTL)

NASDAQ: CSTL · Real-Time Price · USD
22.11
+0.85 (4.00%)
At close: May 28, 2026, 4:00 PM EDT
22.11
0.00 (0.00%)
After-hours: May 28, 2026, 5:33 PM EDT
Market Cap670.60M +36.3%
Revenue (ttm)339.92M -2.1%
Net Income-12.83M
EPS-0.44
Shares Out 30.33M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume242,895
Open21.12
Previous Close21.26
Day's Range21.10 - 22.18
52-Week Range14.59 - 44.28
Beta1.11
AnalystsStrong Buy
Price Target45.88 (+107.51%)
Earnings DateMay 6, 2026

About CSTL

Castle Biosciences, Inc., a molecular diagnostics company, provides test solutions for the diagnosis and treatment of dermatologic cancers, Barrett’s esophagus (BE), atopic dermatitis (AD), and uveal melanoma. The company offers DecisionDx-Melanoma, a risk stratification gene expression profile (GEP) test that predicts the likelihood of a positive sentinel lymph node and the risk of metastasis for patients with invasive cutaneous melanoma; TissueCypher, a risk stratification spatialomics test to predict future development of high-grade dysplasi... [Read more]

Sector Healthcare
IPO Date Jul 25, 2019
Employees 942
Stock Exchange NASDAQ
Ticker Symbol CSTL
Full Company Profile

Financial Performance

Financial Statements

Analyst Summary

According to 8 analysts, the average rating for CSTL stock is "Strong Buy." The 12-month stock price target is $45.88, which is an increase of 107.51% from the latest price.

Price Target
$45.88
(107.51% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Castle Biosciences price target lowered to $40 from $50 at BTIG

BTIG lowered the firm’s price target on Castle Biosciences (CSTL) to $40 from $50 and keeps a Buy rating on the shares. The company delivered a solid 10% revenue beat…

15 days ago - TheFly

Castle Biosciences to Present at the 2026 Jefferies Global Healthcare Conference

FRIENDSWOOD, Texas, May 13, 2026 /PRNewswire/ -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that its executiv...

15 days ago - PRNewsWire

Castle Biosciences' AdvanceAD-Tx™ Test Receives 2026 MedTech Breakthrough Award for Genomics Innovation

This marks the fifth MedTech Breakthrough Award that Castle has earned for its innovative testing solutions FRIENDSWOOD, Texas, May 12, 2026 /PRNewswire/ -- Castle Biosciences, Inc. (Nasdaq: CSTL), a ...

16 days ago - PRNewsWire

Castle Biosciences reports Q1 EPS , consensus (49c)

Reports Q1 revenue $83.7M, consensus $79.23M. “The Castle Biosciences (CSTL) team delivered outstanding results to start 2026, delivering $83.7M in revenue,” said CEO Derek Maetzold. “Our momentum thi...

21 days ago - TheFly

Castle Biosciences raises 2026 revenue view to $345M-$355M from $340M-350M

2026 revenue consensus $345.73M.

21 days ago - TheFly

Castle Biosciences Earnings Call Transcript: Q1 2026

Q1 2026 saw strong revenue and test volume growth, with record months for core products and improved margins. Full-year guidance was raised, and new clinical data reinforced product value. Reimbursement clarity for AdvanceAD-Tx is expected by Q3, with material revenue anticipated in 2027–2028.

22 days ago - Transcripts

Castle Biosciences Slides: Q1 2026

Castle Biosciences has posted slides in relation to its Q1 2026 quarterly earnings report, which was published on May 6, 2026.

22 days ago - Filings

Castle Biosciences Quarterly report: Q1 2026

Castle Biosciences has published its Q1 2026 quarterly earnings report on May 6, 2026.

22 days ago - Filings

Castle Biosciences Earnings release: Q1 2026

Castle Biosciences released its Q1 2026 earnings on May 6, 2026, summarizing the period's financial results.

22 days ago - Filings

Castle Biosciences Reports First Quarter 2026 Results

Delivered Q1 2026 revenue of $83.7 million Q1 2026 total test reports for our core revenue drivers (DecisionDx ® -Melanoma, TissueCypher ®) increased 36% over Q1 2025 Raising full-year 2026 revenue g...

22 days ago - PRNewsWire

Castle Biosciences Supports Nationwide Patient Advocacy and Screening Initiatives to Celebrate Skin Cancer Awareness Month

Longstanding collaborations with AIM at Melanoma, the Melanoma Research Foundation, The Skin Cancer Foundation, IMPACT Melanoma and The Sun Bus continue to advance awareness and education throughout M...

23 days ago - PRNewsWire

New Data at DDW 2026 Show TissueCypher® Testing Improves Risk Stratification and Drives Risk-Aligned Management in Barrett's Esophagus

Clinical studies from Mayo Clinic researchers demonstrate the TissueCypher test provides improved risk stratification and influences risk-aligned surveillance decisions in clinical practice, with one ...

24 days ago - PRNewsWire

Castle Biosciences to Present New Data Demonstrating DecisionDx®-Melanoma's Ability to Identify Patients with Greater Risk of Recurrence and Poor Outcomes Within Early-Stage Melanoma at EADO and ACMS

Multi-center clinical and population-based data show that DecisionDx-Melanoma identifies biologically high-risk patients—including those with thin and early-stage disease—and provides recurrence risk ...

5 weeks ago - PRNewsWire

Castle Biosciences price target lowered to $40 from $50 at Canaccord

Canaccord analyst Kyle Mikson lowered the firm’s price target on Castle Biosciences (CSTL) to $40 from $50 and keeps a Buy rating on the shares. The firm updated its model…

5 weeks ago - TheFly

Castle Biosciences to Release First Quarter 2026 Financial Results and Host Webcast on Wednesday, May 6, 2026

FRIENDSWOOD, Texas, April 15, 2026 /PRNewswire/ -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that it will re...

6 weeks ago - PRNewsWire

Castle Biosciences Earns 2026 USA TODAY Top Workplaces Award for Fifth Consecutive Year

FRIENDSWOOD, Texas, April 10, 2026 /PRNewswire/ -- Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced that it has rec...

6 weeks ago - PRNewsWire

Castle Biosciences Proxy statement: Proxy filing

Castle Biosciences filed a proxy statement on April 8, 2026, providing details for shareholder voting and corporate governance matters.

7 weeks ago - Filings

Castle Biosciences Proxy statement: Proxy filing

Castle Biosciences filed a proxy statement on April 8, 2026, providing details for shareholder voting and corporate governance matters.

7 weeks ago - Filings

Castle Biosciences to present new data from DecisionDx-Melanoma test at AAD

Castle Biosciences (CSTL) will present new data at the 2026 American Academy of Dermatology Annual Meeting, taking place March 27-31 in Denver, demonstrating that its DecisionDx-Melanoma test refines ...

2 months ago - TheFly

Castle Biosciences' DecisionDx®-Melanoma Test Significantly Improves Risk Prediction Within AJCC Stages to Support Personalized, Risk-Aligned Management of Cutaneous Melanoma, Data to Be Presented at AAD 2026

Data from 1,868 Surveillance, Epidemiology and End Results (SEER)-linked patients show DecisionDx-Melanoma significantly stratifies five-year melanoma-specific survival within American Joint Committee...

2 months ago - PRNewsWire

Castle Biosciences Transcript: Status update

The DECIDE study confirms DecisionDx-Melanoma's strong predictive value for sentinel lymph node positivity and recurrence risk, enabling precise risk stratification and safe de-escalation of care for low-risk melanoma patients. The test outperforms competing assays and is widely adopted in clinical practice, supporting its case for guideline inclusion.

2 months ago - Transcripts

Castle Biosciences Slides: Status update

Castle Biosciences has posted slides in relation to its latest quarterly earnings report, which was published on March 23, 2026.

2 months ago - Filings

Castle announces publication of DecisionDx-Melanoma’s i31-SLNB study results

Castle Biosciences (CSTL) announced the publication of results from the largest prospective, multicenter study to date evaluating DecisionDx-Melanoma’s integrated sentinel lymph node biopsy test resul...

2 months ago - TheFly

Prospective, Multi-center Study Published in Future Oncology Demonstrates DecisionDx®-Melanoma's i31-SLNB Result Outperforms Staging Criteria in Identifying Patients with Cutaneous Melanoma Below the 5% NCCN Threshold for Forgoing SLNB

Castle today announced the publication of results from a prospective, multicenter study evaluating DecisionDx-Melanoma's integrated SLNB test result.

2 months ago - GlobeNewsWire

Castle Biosciences announces new data from study evaluating i31SLNB

Castle Biosciences (CSTL) announced new data from the largest prospective multicenter study to date evaluating DecisionDx-Melanoma’s integrated sentinel lymph node biopsy, i31SLNB, test result. The st...

2 months ago - TheFly