Krystal Biotech, Inc. (KRYS)

NASDAQ: KRYS · Real-Time Price · USD
262.67
-20.62 (-7.28%)
At close: Feb 19, 2026, 4:00 PM EST
262.67
0.00 (0.00%)
After-hours: Feb 19, 2026, 4:00 PM EST
Market Cap7.72B +68.1%
Revenue (ttm)389.13M +33.9%
Net Income204.83M +129.7%
EPS6.84 +128.0%
Shares Out 29.23M
PE Ratio38.61
Forward PE33.73
Dividendn/a
Ex-Dividend Daten/a
Volume515,491
Open280.00
Previous Close283.29
Day's Range259.58 - 281.69
52-Week Range122.80 - 298.30
Beta0.48
AnalystsStrong Buy
Price Target281.45 (+6.56%)
Earnings DateFeb 17, 2026

About KRYS

Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, manufactures, and commercializes genetic medicines to treat diseases with high unmet medical needs in the United States. The company commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). It also develops KB803 for ocular complications of dystrophic epidermolysis bullosa; KB801 for neurotrophic keratitis; KB407, which is in Phase 1 clinical trials for treating cystic fibrosis; KB111 for Hailey... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Sep 20, 2017
Employees 295
Stock Exchange NASDAQ
Ticker Symbol KRYS
Full Company Profile

Financial Performance

In 2025, Krystal Biotech's revenue was $389.13 million, an increase of 33.94% compared to the previous year's $290.52 million. Earnings were $204.83 million, an increase of 129.74%.

Financial Statements

Analyst Summary

According to 11 analysts, the average rating for KRYS stock is "Strong Buy." The 12-month stock price target is $281.45, which is an increase of 6.56% from the latest price.

Price Target
$281.45
(6.56% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Krystal Biotech, Inc. (KRYS) Q4 2025 Earnings Call Transcript

Krystal Biotech, Inc. (KRYS) Q4 2025 Earnings Call Transcript

2 days ago - Seeking Alpha

Krystal: Profitable Growth And The Expanding Reach Of HSV-1 Technology

Krystal Biotech remains a "Buy" as VYJUVEK's strong launch powers profitability, and pipeline catalysts offer further upside. Krystal Biotech's valuation is underpinned by VYJUVEK's blockbuster trajec...

2 days ago - Seeking Alpha

Krystal Biotech Announces Fourth Quarter and Full Year 2025 Financial and Operating Results

$107.1 million in 4Q VYJUVEK revenue and $730.3 million since U.S. launch FDA granted RMAT to KB707 for the treatment of advanced NSCLC and Fast Track Designation to KB111 for the treatment of HHD Str...

2 days ago - GlobeNewsWire

Krystal Biotech: KB707 Program Bolstered By RMAT And 2nd Half 2026 Update

Krystal Biotech maintains a 'Strong Buy' rating, driven by robust VYJUVEK sales and significant pipeline progress. Krystal Biotech received FDA RMAT designation for inhaled KB707 in advanced NSCLC, ba...

9 days ago - Seeking Alpha

Krystal Biotech to Report Fourth Quarter and Full Year 2025 Financial Results on February 17, 2026

PITTSBURGH, Feb. 10, 2026 (GLOBE NEWSWIRE) -- Krystal Biotech, Inc. (the “Company”) (NASDAQ: KRYS) announced today that it will report its fourth quarter and full year 2025 financial results on Tuesda...

9 days ago - GlobeNewsWire

Krystal Biotech: Beyond VYJUVEK Commercialization

Krystal Biotech is upgraded to Strong Buy, driven by Vyjuvek's commercial success and a robust catalyst-rich pipeline. KRYS boasts 96% gross margins, nearly $1B in cash, and a platform poised to deliv...

4 weeks ago - Seeking Alpha

These under-the-radar stocks combine fast growth with big upside potential

The companies are projected to grow sales rapidly through 2027, and many of the stocks are expected to show double-digit increases this year.

5 weeks ago - Market Watch

Krystal Biotech, Inc. (KRYS) Presents at 44th Annual J.P. Morgan Healthcare Conference Transcript

Krystal Biotech, Inc. (KRYS) Presents at 44th Annual J.P. Morgan Healthcare Conference Transcript

5 weeks ago - Seeking Alpha

Krystal Biotech Provides Business Update at 44th Annual J.P. Morgan Healthcare Conference

Preliminary 4Q 2025 VYJUVEK net revenue of $106 million to $107 million Robust clinical pipeline with multibillion dollar opportunities and strong balance sheet for sustained growth PITTSBURGH, Jan. 1...

5 weeks ago - GlobeNewsWire

Krystal Biotech, Inc. (KRYS) Discusses Positive Interim Results and Next Steps for Cystic Fibrosis Program KB407 Transcript

Krystal Biotech, Inc. (KRYS) Discusses Positive Interim Results and Next Steps for Cystic Fibrosis Program KB407 Transcript

5 weeks ago - Seeking Alpha

Krystal Biotech to Present at 8th Annual Evercore Healthcare Conference

PITTSBURGH, Nov. 26, 2025 (GLOBE NEWSWIRE) -- Krystal Biotech, Inc . (the “Company”) (NASDAQ: KRYS) today announced that the Company will participate in the 8th Annual Evercore Healthcare Conference o...

3 months ago - GlobeNewsWire

Krystal Biotech: Vyjuvek Gene Therapy Well Positioned For Growth

Krystal Biotech is rated a buy after a strong Vyjuvek launch, but the current valuation reflects premium margins and aggressive global expansion projections. Vyjuvek's US sales growth has plateaued, b...

3 months ago - Seeking Alpha

Krystal's Q3: Platform Designation Adds Pipeline Leverage As Vyjuvek Scales (Rating Upgrade)

Krystal Biotech (KRYS) reported strong Q3 results, with Vyjuvek delivering $97.8M revenue, 96% gross margin, and a new at-home use label. KRYS's disciplined operating expenses and robust cash position...

3 months ago - Seeking Alpha

Krystal Biotech, Inc. (KRYS) Q3 2025 Earnings Call Transcript

Krystal Biotech, Inc. ( KRYS) Q3 2025 Earnings Call November 3, 2025 8:30 AM EST Company Participants Stephane Paquette - Vice President of Corporate Development Krish Krishnan - Founder, Chairman, P...

3 months ago - Seeking Alpha

FDA Expands Krystal Biotech Vyjuvek's Label Allowing Newborns Access To Gene Therapy For Blistering Skin

The U.S. Food and Drug Administration (FDA) on Monday approved Krystal Biotech, Inc.'s KRYS label update for Vyjuvek (beremagene geperpavec-svdt).

5 months ago - Benzinga

Krystal Biotech Announces FDA Approval of Updated VYJUVEK® Label

Revised label allows treatment of DEB patients from birth VYJUVEK can now be applied by patients and caregivers PITTSBURGH, Sept. 15, 2025 (GLOBE NEWSWIRE) -- Krystal Biotech, Inc. (the “Company”) (NA...

5 months ago - GlobeNewsWire

Krystal Biotech: A "Strong Buy" Despite KB707 Melanoma Tumor Targeting Update

I maintain a Strong Buy on Krystal Biotech, as the pause in melanoma trial enrollment is offset by promising progress in inhaled KB707 for NSCLC. Inhaled KB707 achieved a 36% ORR in heavily pretreated...

6 months ago - Seeking Alpha

Krystal Biotech Announces Update on Development Plans for Oncology Program KB707 and Prioritization of Inhaled KB707 for the Treatment of Non-Small Cell Lung Cancer

PITTSBURGH, Aug. 21, 2025 (GLOBE NEWSWIRE) -- Krystal Biotech, Inc. (the “Company”) (NASDAQ: KRYS), a commercial-stage biotechnology company, today announced an update on development plans for KB707, ...

6 months ago - GlobeNewsWire

Krystal Biotech, Inc. (KRYS) Q2 2025 Earnings Call Transcript

Krystal Biotech, Inc. (NASDAQ:KRYS) Q2 2025 Earnings Conference Call August 4, 2025 8:30 AM ET Company Participants Kathryn A. Romano - Executive VP & Chief Accounting Officer Krish S.

7 months ago - Seeking Alpha

Krystal Biotech Announces Approval of VYJUVEK® by Japan's Ministry of Health, Labour and Welfare for the Treatment of Dystrophic Epidermolysis Bullosa

VYJUVEK approved for the treatment of DEB from birth with flexible administration options including home dosing and the option for administration by the patient or their family

7 months ago - GlobeNewsWire

Jeune Announces Positive Results and Significant Aesthetic Improvements from Phase 1 Study of KB304 for Moderate to Severe Wrinkles of the Décolleté

KB304 designed to deliver collagen and elastin to restore skin naturally Conference call to discuss results scheduled for Thursday, July 24, 2025 at 4:30pm ET PITTSBURGH, July 24, 2025 (GLOBE NEWSWIRE...

7 months ago - GlobeNewsWire

Krystal Biotech Announces First Patient Dosed in Phase 1/2 Trial of KB801 for the Treatment of Neurotrophic Keratitis

Eye drop administration of KB801 designed to enable sustained expression of NGF in the front of the eye Investor call and webcast to be held July 9 at 8:30 am ET to discuss program and trial design PI...

8 months ago - GlobeNewsWire

Krystal Biotech Announces First Patient Dosed in Phase 3 Clinical Trial of KB803 for the Treatment and Prevention of Corneal Abrasions in Patients with Dystrophic Epidermolysis Bullosa

Intra-patient, double-blind, multicenter, placebo-controlled study with crossover design Repeat administration under compassionate use was previously shown to be well tolerated and associated with ful...

8 months ago - GlobeNewsWire

Krystal Biotech to Present at BofA Securities 2025 Health Care Conference

PITTSBURGH, May 07, 2025 (GLOBE NEWSWIRE) -- Krystal Biotech, Inc . (the “Company”) (NASDAQ: KRYS) today announced that the Company will participate in the BofA Securities 2025 Health Care Conference ...

10 months ago - GlobeNewsWire

Krystal Biotech, Inc. (KRYS) Q1 2025 Earnings Call Transcript

Krystal Biotech, Inc. (NASDAQ:KRYS) Q1 2025 Earnings Conference Call May 6, 2025 8:30 AM ET Company Participants Stephane Paquette - VP, Corporate Development Krish Krishnan - Chairman and CEO Suma K...

10 months ago - Seeking Alpha