Lyell Immunopharma, Inc. (LYEL)

NASDAQ: LYEL · Real-Time Price · USD
11.97
-1.08 (-8.28%)
At close: Jun 5, 2026, 4:00 PM EDT
12.20
+0.23 (1.92%)
After-hours: Jun 5, 2026, 6:30 PM EDT
Market Cap279.31M +124.2%
Revenue (ttm)31,000 -52.3%
Net Income-246.41M
EPS-13.06
Shares Out 23.33M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume96,677
Open12.99
Previous Close13.05
Day's Range11.70 - 13.51
52-Week Range8.46 - 45.00
Beta-0.09
AnalystsStrong Buy
Price Target42.20 (+252.55%)
Earnings DateMay 6, 2026

About LYEL

Lyell Immunopharma, Inc., a clinical-stage cell therapy company, develops chimeric antigen receptor (CAR) T-cell product candidates for patients with hematologic malignancies and solid tumors. The company’s lead product candidate include rondecabtagene autoleucel, an autologous dual‑targeting CD19/CD20 CAR T‑cell therapy in development, which is in pivotal PiNACLE trial in the 3L+ setting and in a Phase 1/2 clinical trial in the 2L setting, as well as a second pivotal trial, PiNACLE-H2H, which is a Phase 3 head-to-head CAR T cell therapy random... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Jun 17, 2021
Employees 161
Stock Exchange NASDAQ
Ticker Symbol LYEL
Full Company Profile

Financial Performance

In 2025, Lyell Immunopharma's revenue was $36,000, a decrease of -40.98% compared to the previous year's $61,000. Losses were -$274.45 million, -19.98% less than in 2024.

Financial Statements

Analyst Summary

According to 5 analysts, the average rating for LYEL stock is "Strong Buy." The 12-month stock price target is $42.2, which is an increase of 252.55% from the latest price.

Price Target
$42.2
(252.55% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Lyell Immunopharma to Present Phase 1/2 Safety and Translational Data for Ronde-Cel in Large B-Cell Lymphoma at the European Hematology Association 2026 Congress

SOUTH SAN FRANCISCO, Calif., June 04, 2026 (GLOBE NEWSWIRE) -- Lyell Immunopharma, Inc. (Nasdaq: LYEL), a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor ...

1 day ago - GlobeNewsWire

Lyell Immunopharma Announces Participation in Goldman Sachs 47th Annual Global Healthcare Conference 2026

SOUTH SAN FRANCISCO, Calif., June 01, 2026 (GLOBE NEWSWIRE) -- Lyell Immunopharma, Inc. (Nasdaq: LYEL), a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor ...

4 days ago - GlobeNewsWire

Lyell Immunopharma Transcript: Stifel 2026 Targeted Oncology Virtual Forum

The company is advancing next-generation cell therapies with strong clinical data for ronde-cel in lymphoma and a novel dual CAR for colorectal cancer. Regulatory and manufacturing strategies are robust, with pivotal data and major updates expected soon. Cash reserves support operations through key milestones.

16 days ago - Transcripts

Lyell Immunopharma Transcript: H.C. Wainwright 4th Annual BioConnect Investor Conference

Ronde-cel leads the CD19/CD20 CAR T-cell space with strong efficacy, safety, and manufacturing readiness, outpacing competitors and targeting a large third-line lymphoma market. The colorectal cancer program shows promising, durable responses. Key pivotal data updates and regulatory milestones are expected this year and next.

17 days ago - Transcripts

Lyell Immunopharma Announces Participation in May Investor Conferences

SOUTH SAN FRANCISCO, Calif., May 12, 2026 (GLOBE NEWSWIRE) -- Lyell Immunopharma, Inc. (Nasdaq: LYEL), a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor (...

24 days ago - GlobeNewsWire

Lyell Immunopharma Reports Business Highlights and Financial Results for the First Quarter 2026

PiNACLE pivotal clinical trial evaluating ronde-cel in patients with LBCL in third- or later-line setting on track to report additional data in second half of 2026, with pivotal data expected mid-2027...

4 weeks ago - GlobeNewsWire

Lyell Immunopharma Quarterly report: Q1 2026

Lyell Immunopharma has published its Q1 2026 quarterly earnings report on May 6, 2026.

4 weeks ago - Filings

Lyell Immunopharma Earnings release: Q1 2026

Lyell Immunopharma released its Q1 2026 earnings on May 6, 2026, summarizing the period's financial results.

4 weeks ago - Filings

Lyell Immunopharma initiated with an Outperform at Baird on ronde-cel potential

As previously reported, Baird initiated coverage of Lyell Immunopharma (LYEL) with an Outperform rating and $49 price target Lyell’s pipeline is headlined by ronde-cel, for which a pair of pivotal…

5 weeks ago - TheFly

Lyell Immunopharma initiated with an Outperform at Baird

Baird initiated coverage of Lyell Immunopharma (LYEL) with an Outperform rating and $49 price target

5 weeks ago - TheFly

Lyell Immunopharma Proxy statement: Proxy filing

Lyell Immunopharma filed a proxy statement on April 24, 2026, providing details for shareholder voting and corporate governance matters.

6 weeks ago - Filings

Lyell Immunopharma Proxy statement: Proxy filing

Lyell Immunopharma filed a proxy statement on April 24, 2026, providing details for shareholder voting and corporate governance matters.

6 weeks ago - Filings

Lyell Immunopharma Transcript: 25th Annual Needham Virtual Healthcare Conference

The company is advancing next-generation CAR T-cell therapies, with ronde-cel showing high response rates and a favorable safety profile in pivotal trials. Manufacturing is fully in-house, and commercial launch is targeted for next year. LYL273 for solid tumors is also progressing, with promising early data and upcoming disclosures.

7 weeks ago - Transcripts

Lyell Immunopharma Stock (LYEL) Slides Despite Praise from a Top Wall Street Analyst

Lyell Immunopharma stock was down despite praise from a top Wall Street analyst on Friday.

2 months ago - TipRanks

Lyell Immunopharma initiated with a Buy at Needham

Needham initiated coverage of Lyell Immunopharma (LYEL) with a Buy rating and $44 price target The firm says the company’s ronde-cel is in the “pole position” for second-line diffuse large…

2 months ago - TheFly

Lyell Immunopharma Announces Participation in 25th Annual Needham Virtual Healthcare Conference

SOUTH SAN FRANCISCO, Calif., April 07, 2026 (GLOBE NEWSWIRE) -- Lyell Immunopharma, Inc. (Nasdaq: LYEL), a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor...

2 months ago - GlobeNewsWire

Lyell Immunopharma Registration statement: Registration filing

Lyell Immunopharma filed a registration statement on April 3, 2026, providing details about a securities offering with the SEC.

2 months ago - Filings

Lyell Immunopharma price target raised to $39 from $32 at Lucid Capital

Lucid Capital analyst Christopher Liu raised the firm’s price target on Lyell Immunopharma (LYEL) to $39 from $32 and keeps a Buy rating on the shares following the fiscal 2025…

3 months ago - TheFly

Lyell Immunopharma Reports Q4 and Full Year 2025 Business and Financial Results

SOUTH SAN FRANCISCO, Calif., March 12, 2026 (GLOBE NEWSWIRE) -- Lyell Immunopharma, Inc. (Nasdaq: LYEL), a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor...

3 months ago - GlobeNewsWire

Lyell Immunopharma Annual report: Q4 2025

Lyell Immunopharma has published its Q4 2025 annual report on March 12, 2026.

3 months ago - Filings

Lyell Immunopharma Earnings release: Q4 2025

Lyell Immunopharma released its Q4 2025 earnings on March 12, 2026, summarizing the period's financial results.

3 months ago - Filings

Lyell Immunopharma Transcript: The Citizens Life Sciences Conference 2026

Multiple pivotal trials are advancing for next-generation CAR T-cell therapies in lymphoma and colorectal cancer, with strong early efficacy and safety data. Major data updates are expected in H2, and financial resources are secured for continued development.

3 months ago - Transcripts

Lyell Immunopharma Transcript: Leerink Global Healthcare Conference 2026

Key updates include a new CFO hire, a $50M financing milestone, and strong clinical progress for the dual-targeted ronde-cel CAR T-cell therapy, which shows high response rates and a favorable safety profile. The company is also advancing a novel GCC CAR T-cell program for solid tumors, with promising early data and upcoming readouts.

3 months ago - Transcripts

Lyell Immunopharma appoints Smital Shah as CFBO

Lyell Immunopharma (LYEL) closed the sale of an additional $50M of shares of its common stock to investors from its July 2025 equity private placement of up to $100M, following…

3 months ago - TheFly

Lyell Immunopharma Announces Closing of Additional $50 Million Tranche of Equity Private Placement and Appointment of Smital Shah as Chief Financial and Business Officer

SOUTH SAN FRANCISCO, Calif., March 09, 2026 (GLOBE NEWSWIRE) -- Lyell Immunopharma, Inc. (Nasdaq: LYEL), a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor...

3 months ago - GlobeNewsWire