Lyell Immunopharma, Inc. (LYEL)

NASDAQ: LYEL · Real-Time Price · USD
12.52
+0.03 (0.20%)
Jun 26, 2026, 12:45 PM EDT - Market open
Market Cap292.03M +82.6%
Revenue (ttm)31,000 -52.3%
Net Income-246.41M
EPS-13.06
Shares Out 23.33M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume25,042
Open12.38
Previous Close12.49
Day's Range12.24 - 12.68
52-Week Range8.46 - 45.00
Beta-0.09
AnalystsBuy
Price Target37.17 (+197.0%)
Earnings DateAug 11, 2026

About LYEL

Lyell Immunopharma, Inc., a clinical-stage cell therapy company, develops chimeric antigen receptor (CAR) T-cell product candidates for patients with hematologic malignancies and solid tumors. The company’s lead product candidate include rondecabtagene autoleucel, an autologous dual‑targeting CD19/CD20 CAR T‑cell therapy in development, which is in pivotal PiNACLE trial in the 3L+ setting and in a Phase 1/2 clinical trial in the 2L setting, as well as a second pivotal trial, PiNACLE-H2H, which is a Phase 3 head-to-head CAR T cell therapy random... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Jun 17, 2021
Employees 161
Stock Exchange NASDAQ
Ticker Symbol LYEL
Full Company Profile

Financial Performance

In 2025, Lyell Immunopharma's revenue was $36,000, a decrease of -40.98% compared to the previous year's $61,000. Losses were -$274.45 million, -19.98% less than in 2024.

Financial Statements

Analyst Summary

According to 6 analysts, the average rating for LYEL stock is "Buy." The 12-month stock price target is $37.17, which is an increase of 197.00% from the latest price.

Price Target
$37.17
(197.00% upside)
Analyst Consensus: Buy
Stock Forecasts

News

Lyell Immunopharma Announces Participation in H.C. Wainwright 4th Annual Cell Therapy Virtual Conference

SOUTH SAN FRANCISCO, Calif., June 25, 2026 (GLOBE NEWSWIRE) -- Lyell Immunopharma, Inc. (Nasdaq: LYEL), a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor ...

1 day ago - GlobeNewsWire

Lyell Immunopharma Presents Updated Safety Data and Translational Insights for Rondecabtagene Autoleucel (Ronde-Cel) in Patients with Large B-Cell Lymphoma at European Hematology Association 2026 Congress

More than 100 patients treated with ronde-cel in 2L and 3L+ LBCL, with a manufacturing success rate of 97% No Grade ≥ 3 CRS and low rates of Grade ≥ 3 ICANS, supporting outpatient administration Trans...

14 days ago - GlobeNewsWire

Lyell Immunopharma Transcript: AGM 2026

The meeting covered director elections, auditor ratification, and executive compensation, all of which were approved by shareholders. No questions were raised, and voting results will be reported on Form 8-K within four business days.

16 days ago - Transcripts

Lyell Immunopharma Transcript: Goldman Sachs 47th Annual Global Healthcare Conference 2026

Major data updates for dual-targeting CAR T in lymphoma are expected in the second half, with pivotal data and BLA submission targeted for 2027. The colorectal cancer CAR T program shows improved safety and potential for expansion. Strong physician enthusiasm and a solid cash runway support ongoing clinical progress.

18 days ago - Transcripts

Lyell Immunopharma provides update on safety profile of LYL273

Lyell Immunopharma (LYEL) provided an update on the safety profile of LYL273 in its ongoing U.S. Phase 1 clinical trial in patients with relapsed or refractory metastatic colorectal cancer, and…

18 days ago - TheFly

Lyell Immunopharma Provides Update on Safety Profile of LYL273 in Relapsed or Refractory Metastatic Colorectal Cancer and Amends Phase 1 Trial to Phase 1/2 Expansion

SOUTH SAN FRANCISCO, Calif., June 08, 2026 (GLOBE NEWSWIRE) -- Lyell Immunopharma, Inc. (Nasdaq: LYEL), a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor ...

18 days ago - GlobeNewsWire

Lyell Immunopharma to Present Phase 1/2 Safety and Translational Data for Ronde-Cel in Large B-Cell Lymphoma at the European Hematology Association 2026 Congress

SOUTH SAN FRANCISCO, Calif., June 04, 2026 (GLOBE NEWSWIRE) -- Lyell Immunopharma, Inc. (Nasdaq: LYEL), a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor ...

21 days ago - GlobeNewsWire

Lyell Immunopharma Announces Participation in Goldman Sachs 47th Annual Global Healthcare Conference 2026

SOUTH SAN FRANCISCO, Calif., June 01, 2026 (GLOBE NEWSWIRE) -- Lyell Immunopharma, Inc. (Nasdaq: LYEL), a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor ...

25 days ago - GlobeNewsWire

Lyell Immunopharma Transcript: Stifel 2026 Targeted Oncology Virtual Forum

The company is advancing next-generation cell therapies with strong clinical data for ronde-cel in lymphoma and a novel dual CAR for colorectal cancer. Regulatory and manufacturing strategies are robust, with pivotal data and major updates expected soon. Cash reserves support operations through key milestones.

5 weeks ago - Transcripts

Lyell Immunopharma Transcript: H.C. Wainwright 4th Annual BioConnect Investor Conference

Ronde-cel leads the CD19/CD20 CAR T-cell space with strong efficacy, safety, and manufacturing readiness, outpacing competitors and targeting a large third-line lymphoma market. The colorectal cancer program shows promising, durable responses. Key pivotal data updates and regulatory milestones are expected this year and next.

5 weeks ago - Transcripts

Lyell Immunopharma Announces Participation in May Investor Conferences

SOUTH SAN FRANCISCO, Calif., May 12, 2026 (GLOBE NEWSWIRE) -- Lyell Immunopharma, Inc. (Nasdaq: LYEL), a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor (...

6 weeks ago - GlobeNewsWire

Lyell Immunopharma Reports Business Highlights and Financial Results for the First Quarter 2026

PiNACLE pivotal clinical trial evaluating ronde-cel in patients with LBCL in third- or later-line setting on track to report additional data in second half of 2026, with pivotal data expected mid-2027...

7 weeks ago - GlobeNewsWire

Lyell Immunopharma Quarterly report: Q1 2026

Lyell Immunopharma has published its Q1 2026 quarterly earnings report on May 6, 2026.

7 weeks ago - Filings

Lyell Immunopharma Earnings release: Q1 2026

Lyell Immunopharma released its Q1 2026 earnings on May 6, 2026, summarizing the period's financial results.

7 weeks ago - Filings

Lyell Immunopharma initiated with an Outperform at Baird on ronde-cel potential

As previously reported, Baird initiated coverage of Lyell Immunopharma (LYEL) with an Outperform rating and $49 price target Lyell’s pipeline is headlined by ronde-cel, for which a pair of pivotal…

2 months ago - TheFly

Lyell Immunopharma initiated with an Outperform at Baird

Baird initiated coverage of Lyell Immunopharma (LYEL) with an Outperform rating and $49 price target

2 months ago - TheFly

Lyell Immunopharma Proxy statement: Proxy filing

Lyell Immunopharma filed a proxy statement on April 24, 2026, providing details for shareholder voting and corporate governance matters.

2 months ago - Filings

Lyell Immunopharma Proxy statement: Proxy filing

Lyell Immunopharma filed a proxy statement on April 24, 2026, providing details for shareholder voting and corporate governance matters.

2 months ago - Filings

Lyell Immunopharma Transcript: 25th Annual Needham Virtual Healthcare Conference

The company is advancing next-generation CAR T-cell therapies, with ronde-cel showing high response rates and a favorable safety profile in pivotal trials. Manufacturing is fully in-house, and commercial launch is targeted for next year. LYL273 for solid tumors is also progressing, with promising early data and upcoming disclosures.

2 months ago - Transcripts

Lyell Immunopharma Stock (LYEL) Slides Despite Praise from a Top Wall Street Analyst

Lyell Immunopharma stock was down despite praise from a top Wall Street analyst on Friday.

2 months ago - TipRanks

Lyell Immunopharma initiated with a Buy at Needham

Needham initiated coverage of Lyell Immunopharma (LYEL) with a Buy rating and $44 price target The firm says the company’s ronde-cel is in the “pole position” for second-line diffuse large…

2 months ago - TheFly

Lyell Immunopharma Announces Participation in 25th Annual Needham Virtual Healthcare Conference

SOUTH SAN FRANCISCO, Calif., April 07, 2026 (GLOBE NEWSWIRE) -- Lyell Immunopharma, Inc. (Nasdaq: LYEL), a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor...

2 months ago - GlobeNewsWire

Lyell Immunopharma Registration statement: Registration filing

Lyell Immunopharma filed a registration statement on April 3, 2026, providing details about a securities offering with the SEC.

3 months ago - Filings

Lyell Immunopharma price target raised to $39 from $32 at Lucid Capital

Lucid Capital analyst Christopher Liu raised the firm’s price target on Lyell Immunopharma (LYEL) to $39 from $32 and keeps a Buy rating on the shares following the fiscal 2025…

3 months ago - TheFly

Lyell Immunopharma Reports Q4 and Full Year 2025 Business and Financial Results

SOUTH SAN FRANCISCO, Calif., March 12, 2026 (GLOBE NEWSWIRE) -- Lyell Immunopharma, Inc. (Nasdaq: LYEL), a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor...

3 months ago - GlobeNewsWire