Company Description
NuCana plc, a clinical-stage biopharmaceutical company, engages in the development of medicines to treat patients with cancer.
It applies its ProTide technology to transform prescribed chemotherapy agents and nucleoside analogs into medicines.
The company is developing medicines to overcome the limitations of nucleoside analogs and generate anti-cancer metabolites in cancer cells.
Its pipeline includes NUC-3373, a chemical entity derived from the nucleoside analog 5-fluorouracil that is in Phase 1b/2 study in patients with metastatic colorectal cancer; Phase 2 clinical trial for the second-line treatment of patients with advanced colorectal cancer; and Phase 1 modular clinical trial for patients with advanced solid tumors and lung cancer.
The company is also developing NUC-7738, a ProTide transformation of 3’-deoxyadenosine, which is in the Phase 2 part of a Phase 1/2 clinical trial for patients with advanced solid tumors.
The company has an assignment, license, and collaboration agreement with Cardiff ProTides Ltd to discover, drug design, and in vitro screen purine and pyrimidine-based nucleosides as potential drug candidates.
The company was formerly known as NuCana BioMed Limited and changed its name to NuCana plc in August 2017.
NuCana plc was incorporated in 1997 and is based in Edinburgh, the United Kingdom.
| Country | United Kingdom |
| Founded | 1997 |
| IPO Date | Sep 28, 2017 |
| Industry | Biotechnology |
| Sector | Healthcare |
| Employees | 22 |
| CEO | Hugh Griffith |
Contact Details
Address: 3 Lochside Way Edinburgh, EH12 9DT United Kingdom | |
| Phone | 44 13 1357 1111 |
| Website | nucana.com |
Stock Details
| Ticker Symbol | NCNA |
| Exchange | NASDAQ |
| Fiscal Year | January - December |
| Reporting Currency | GBP |
| CIK Code | 0001709626 |
| CUSIP Number | 67022C106 |
| ISIN Number | US67022C2052 |
| SIC Code | 2834 |
Key Executives
| Name | Position |
|---|---|
| Hugh Stephen Griffith | Founder, Chief Executive Officer and Executive Director |
| David Harrison | Head of Translational Medicine and Studies |
| Dr. Jeffrey D. Bloss F.A.C.O.G., M.D. | Chief Medical Officer |
| Theresa Bruce | Senior Vice President of Clinical Operations |
| Elisabeth Oelmann | Senior Vice President of Medical and Clinical Development |
| Gordon Kennovin | Senior Vice President of CMC and Development |
| Dr. Stuart Grant | Senior Vice President of Regulatory Affairs |
| Martin Alexander Quinn | Company Secretary |
Latest SEC Filings
| Date | Type | Title |
|---|---|---|
| Jul 16, 2025 | F-6 POS | Post-effective amendments for immediately effective filing |
| Jul 11, 2025 | 6-K | Report of foreign issuer |
| Jul 9, 2025 | 6-K | Report of foreign issuer |
| Jun 30, 2025 | 6-K | Report of foreign issuer |
| Jun 27, 2025 | 424B5 | Filing |
| Jun 27, 2025 | 6-K | Report of foreign issuer |
| Jun 24, 2025 | EFFECT | Notice of Effectiveness |
| Jun 20, 2025 | 6-K | Report of foreign issuer |
| Jun 18, 2025 | F-3/A | Filing |
| Jun 18, 2025 | 6-K | Report of foreign issuer |