NuCana plc (NCNA)
Company Description
NuCana plc, a clinical-stage biopharmaceutical company, engages in the development of medicines to treat patients with cancer.
The company applies its ProTide technology to transform prescribed chemotherapy agents and nucleoside analogs into medicines.
The company, through its technology, is developing medicines, ProTides, to overcome the limitations of nucleoside analogs and generate much higher concentrations of anti-cancer metabolites in cancer cells.
Its pipeline includes NUC-3373, a chemical entity derived from the nucleoside analog 5-fluorouracil, which is in a Phase 1b/2 study in patients with metastatic colorectal cancer.
The company also initiated a randomized Phase 2 study of NUC-3373, in combination with other agents, for the second-line treatment of patients with advanced colorectal cancer; and initiated a Phase 1b/2 modular study of NUC-3373 in combination with the PD-1 inhibitor pembrolizumab for patients with advanced solid tumors and in combination with docetaxel for patients with lung cancer.
Its pipeline also comprises NUC-7738, a transformation of 3'-deoxyadenosine that is in the Phase 2 part of a Phase 1/2 study in patients with advanced solid tumors which is evaluating NUC-7738 as a monotherapy and in combination with pembrolizumab.
It has a research, collaboration, and license agreement with Cardiff University and University College Cardiff Consultants Ltd. for the design, synthesis, characterization, and evaluation of ProTides; and an assignment, license, and collaboration agreement with Cardiff ProTides Ltd. The company was formerly known as NuCana BioMed Limited and changed its name to NuCana plc in August 2017.
NuCana plc was incorporated in 1997 and is headquartered in Edinburgh, the United Kingdom.
Country | United Kingdom |
IPO Date | Sep 28, 2017 |
Industry | Biotechnology |
Sector | Healthcare |
Employees | 28 |
CEO | Hugh Stephen Griffith |
Contact Details
Address: 3 Lochside Way Edinburgh, X0 EH12 9DT United Kingdom | |
Phone | 44-0-131-357-1111 |
Website | nucana.com |
Stock Details
Ticker Symbol | NCNA |
Exchange | NASDAQ |
Fiscal Year | January - December |
Reporting Currency | USD |
CIK Code | 0001709626 |
CUSIP Number | 67022C106 |
ISIN Number | US67022C1062 |
SIC Code | 2834 |
Key Executives
Name | Position |
---|---|
Hugh Stephen Griffith | Founder, Chief Executive Officer and Executive Director |
Donald Munoz | Chief Financial Officer |
David Harrison | Head of Translational Medicine |
Dr. Jeffrey D. Bloss F.A.C.O.G., M.D. | Chief Medical Officer |
Prof. Christopher B. Wood FRCS, M.D., Ph.D. | Chief Medical Officer |
Theresa Bruce | Senior Vice President of Clinical Operations |
Elisabeth Oelmann | Senior Vice President of Medical and Clinical Development |
Martin Quinn | Company Secretary |
Latest SEC Filings
Date | Type | Title |
---|---|---|
Mar 27, 2024 | F-6 POS | Post-effective amendments for immediately effective filing |
Mar 27, 2024 | 424B5 | Filing |
Mar 27, 2024 | 6-K | Report of foreign issuer |
Mar 20, 2024 | 20-F | Annual and transition report of foreign private issuers |
Mar 20, 2024 | 6-K | Report of foreign issuer |
Feb 27, 2024 | SC 13D/A | [Amend] General statement of acquisition of beneficial ownership |
Feb 14, 2024 | SC 13G/A | [Amend] Statement of acquisition of beneficial ownership by individuals |
Jan 26, 2024 | SC 13G/A | [Amend] Statement of acquisition of beneficial ownership by individuals |
Nov 16, 2023 | 6-K | Report of foreign issuer |
Nov 13, 2023 | 6-K | Report of foreign issuer |