Orchestra BioMed Holdings, Inc. (OBIO)

NASDAQ: OBIO · Real-Time Price · USD
4.000
+0.020 (0.50%)
At close: May 19, 2026, 4:00 PM EDT
3.995
-0.005 (-0.13%)
After-hours: May 19, 2026, 6:19 PM EDT
Market Cap239.52M +128.2%
Revenue (ttm)32.72M +1,033.9%
Net Income-54.93M
EPS-1.02
Shares Out 59.88M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume490,675
Open3.980
Previous Close3.980
Day's Range3.956 - 4.155
52-Week Range2.200 - 5.424
Beta0.52
AnalystsBuy
Price Target12.29 (+207.25%)
Earnings DateMay 12, 2026

About OBIO

Orchestra BioMed Holdings, Inc. operates as a biomedical company in the United States. The company’s flagship product candidates include Atrioventricular Interval Modulation, a bioelectronic therapy candidate designed to immediately, substantially, and persistently lower blood pressure; and Virtue Sirolimus AngioInfusion Balloon for the treatment of atherosclerotic artery disease. It also develops Cardiac Neuromodulation Therapy for heart failure, or potential treatment of clinical indications, such as urology or osteoarthritis; and CNT-HF, a b... [Read more]

Industry Biotechnology
Sector Healthcare
Founded 2017
Employees 86
Stock Exchange NASDAQ
Ticker Symbol OBIO
Full Company Profile

Financial Performance

In 2025, Orchestra BioMed Holdings's revenue was $33.48 million, an increase of 1169.22% compared to the previous year's $2.64 million. Losses were -$52.96 million, -13.22% less than in 2024.

Financial Statements

Analyst Summary

According to 8 analysts, the average rating for OBIO stock is "Buy." The 12-month stock price target is $12.29, which is an increase of 207.25% from the latest price.

Price Target
$12.29
(207.25% upside)
Analyst Consensus: Buy
Stock Forecasts

News

Orchestra BioMed price target lowered to $10 from $12 at B. Riley

B. Riley lowered the firm’s price target on Orchestra BioMed (OBIO) to $10 from $12 and keeps a Buy rating on the shares. Orchestra BioMed reported Q1 results alongside key…

11 hours ago - TheFly

Orchestra BioMed to Participate in the Jefferies Global Healthcare Conference

NEW HOPE, Pa., May 19, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO, “Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to patie...

12 hours ago - GlobeNewsWire

Orchestra BioMed price target raised to $13 from $12 at Barclays

Barclays analyst Matt Miksic raised the firm’s price target on Orchestra BioMed (OBIO) to $13 from $12 and keeps an Overweight rating on the shares. The company’s better than expected…

6 days ago - TheFly

Orchestra BioMed reports Q1 EPS (33c), consensus (44c)

Reports Q1 revenue $110,000, consensus $160,830. David Hochman, chairman and CEO of Orchestra BioMed (OBIO) stated, “We continued to make meaningful advancements across our late-stage cardiovascular p...

7 days ago - TheFly

Orchestra BioMed Reports First Quarter 2026 Financial Results and Highlights Recent Business Updates

NEW HOPE, Pa., May 12, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO, “Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to patie...

7 days ago - GlobeNewsWire

Orchestra BioMed gives clinical, regulatory update on BACKBEAT trial timeline

Orchestra BioMed (OBIO) announced an update to the overall clinical and regulatory timeline for the BACKBEAT Trial evaluating Atrioventricular Interval Modulation Therapy in pacemaker-indicated patien...

Other symbols: MDT
7 days ago - TheFly

Orchestra BioMed Targeting BACKBEAT Trial Enrollment Completion By End of Q3 2026 and Data Presentation in Q2 2027

NEW HOPE, Pa., May 12, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to pati...

7 days ago - GlobeNewsWire

Orchestra BioMed Holdings Quarterly report: Q1 2026

Orchestra BioMed Holdings has published its Q1 2026 quarterly earnings report on May 12, 2026.

7 days ago - Filings

Orchestra BioMed Holdings Earnings release: Q1 2026

Orchestra BioMed Holdings released its Q1 2026 earnings on May 12, 2026, summarizing the period's financial results.

7 days ago - Filings

Orchestra BioMed receives $15M payment from Ligand

Orchestra BioMed (OBIO) announced the receipt of a $15M payment from Ligand (LGND) pursuant to the previously disclosed revenue participation right purchase and sale agreement. The payment completes a...

Other symbols: LGND
12 days ago - TheFly

Orchestra BioMed Receives $15 Million Investment from Ligand Under Previously Announced Strategic Financing Agreement

NEW HOPE, Pa., May 06, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to pati...

13 days ago - GlobeNewsWire

Orchestra BioMed Receives $20 Million Payment from Medtronic Under Previously Announced Financing Agreement

Payment fulfills previously disclosed funding commitment of $20 million and supports planned completion of the BACKBEAT Global Pivotal Trial (“BACKBEAT Trial”) evaluating Atrioventricular Interval Mod...

Other symbols: MDT
13 days ago - GlobeNewsWire

Orchestra granted additional breakthrough device designation for AVIM therapy

Orchestra BioMed (OBIO) announced that the FDA has granted a second breakthrough device designation, or BDD, for AVIM therapy specific to patients with uncontrolled hypertension despite the use of ant...

Other symbols: MDT
19 days ago - TheFly

FDA Grants Orchestra BioMed Additional Breakthrough Device Designation for AVIM Therapy

Atrioventricular Interval Modulation (“AVIM”) Therapy Food and Drug Administration (“FDA”) Breakthrough Device Designations span the broader population of patients with uncontrolled hypertension despi...

Other symbols: MDT
19 days ago - GlobeNewsWire

Orchestra BioMed Holdings Proxy statement: Proxy filing

Orchestra BioMed Holdings filed a proxy statement on April 29, 2026, providing details for shareholder voting and corporate governance matters.

20 days ago - Filings

Orchestra BioMed Holdings Proxy statement: Proxy filing

Orchestra BioMed Holdings filed a proxy statement on April 29, 2026, providing details for shareholder voting and corporate governance matters.

20 days ago - Filings

Orchestra BioMed to Present AVIM Therapy Clinical and Mechanistic Data at HRS 2026

NEW HOPE, Pa., April 23, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to pa...

26 days ago - GlobeNewsWire

Orchestra BioMed Holdings Slides: Corporate presentation

Orchestra BioMed Holdings has posted slides in relation to its latest quarterly earnings report, which was published on April 1, 2026.

6 weeks ago - Filings

Orchestra BioMed reports FY25 EPS ($1.11), consensus ($1.74)

Reports FY25 revenue $33.482M, consensus $3.47M. David Hochman, Chairman and Chief Executive Officer of Orchestra BioMed (OBIO) stated, “We are very proud of our significant clinical, strategic and fi...

2 months ago - TheFly

Orchestra BioMed Reports Full Year 2025 Financial Results and Provides Fourth Quarter Business Update

NEW HOPE, Pa., March 12, 2026 (GLOBE NEWSWIRE) -- Orchestra BioMed Holdings, Inc. (Nasdaq: OBIO) (“Orchestra BioMed” or the “Company”), a biomedical company accelerating high-impact technologies to pa...

2 months ago - GlobeNewsWire

Orchestra BioMed Holdings Earnings release: Q4 2025

Orchestra BioMed Holdings released its Q4 2025 earnings on March 12, 2026, summarizing the period's financial results.

2 months ago - Filings

Orchestra BioMed Holdings Annual report: Q4 2025

Orchestra BioMed Holdings has published its Q4 2025 annual report on March 12, 2026.

2 months ago - Filings

Orchestra BioMed Holdings Transcript: Barclays 28th Annual Global Healthcare Conference

Two pivotal cardiovascular programs are advancing, with Virtue DEB offering a novel sirolimus-based delivery and AVIM therapy showing strong enrollment and immediate blood pressure benefits. Strategic partnerships have secured funding and minimized dilution, with AVIM commercialization targeted for 2028.

2 months ago - Transcripts

Orchestra BioMed Holdings Transcript: TD Cowen 46th Annual Health Care Conference

Two pivotal trials are underway for AVIM therapy and Virtue SAB, targeting large hypertension and coronary artery disease markets. Strong partnerships with Medtronic and Terumo, robust clinical data, and a royalty-based model position the company for significant growth, with key milestones expected by 2027.

2 months ago - Transcripts

Orchestra BioMed announces two presentations at THT, CRT 2026 meetings

Orchestra BioMed (OBIO) announced two presentations that will be given at the Technology Heart Failure and Therapeutics, THT, and Cardiovascular Research Technologies, CRT, 2026 Meetings highlighting ...

2 months ago - TheFly