Palisade Bio, Inc. (PALI)

NASDAQ: PALI · Real-Time Price · USD
1.975
-0.115 (-5.50%)
At close: Jul 1, 2026, 4:00 PM EDT
1.970
-0.005 (-0.25%)
After-hours: Jul 1, 2026, 4:01 PM EDT
Market Cap344.56M +11,124.4%
Revenue (ttm)n/a
Net Income-24.15M
EPS-0.23
Shares Out 173.58M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume3,692,439
Open2.100
Previous Close2.090
Day's Range1.960 - 2.170
52-Week Range0.530 - 2.855
Beta1.49
AnalystsStrong Buy
Price Target10.50 (+428.97%)
Earnings DateAug 10, 2026

About PALI

Palisade Bio, Inc., a clinical-stage biopharmaceutical company, engages in developing oral phosphodiesterase-4 inhibitor prodrugs designed for targeted delivery to the terminal ileum and colon in the United States. Its lead clinical product candidate includes PALI-2108, which is in phase 1b clinical trial to treat patients with inflammatory bowel disease, including ulcerative colitis and Fibrostenotic Crohn’s disease. The company has a research collaboration and license agreement with Giiant Pharma, Inc. for the development, manufacture, and co... [Read more]

Industry Biotechnology
Sector Healthcare
Founded 1996
Employees 14
Stock Exchange NASDAQ
Ticker Symbol PALI
Full Company Profile

Financial Performance

Financial Statements

Analyst Summary

According to 8 analysts, the average rating for PALI stock is "Strong Buy." The 12-month stock price target is $10.5, which is an increase of 428.97% from the latest price.

Price Target
$10.5
(428.97% upside)
Analyst Consensus: Strong Buy
Stock Forecasts

News

Palisade Bio receives FDA clearance to start ulcerative colitis study

Palisade Bio (PALI) announced that the U.S. Food and Drug Administration has cleared its Investigational New Drug application for its oral drug candidate, PALI-2108. The clearance allows the company t...

2 days ago - TheFly

Palisade Bio Receives FDA Clearance of IND for PALI-2108 and Plans to Initiate Global Phase 2 ASCENTRA-UC Study in Ulcerative Colitis

ASCENTRA-UC expected to enroll up to 204 patients with moderately to severely active ulcerative colitis across North America and Europe

2 days ago - GlobeNewsWire

Palisade Bio Welcomes Biopharmaceutical Industry Veterans Robert Baltera and Jordan Zwick to its Board of Directors

Board strengthened with extensive biotechnology leadership, strategic transactions and capital markets expertise Company continues to build on PALI-2108 clinical progress as it advances toward Phase 2...

20 days ago - GlobeNewsWire

Palisade Bio to Present on the Potential of PALI-2108 for Fibrostenotic Crohn's Disease at New York Academy of Sciences Symposium

Presentation to highlight fibrostenotic Crohn's disease biology and the potential of a locally bioactivated PDE4 inhibitor prodrug approach

22 days ago - GlobeNewsWire

Palisade Bio Transcript: Jefferies Global Healthcare Conference 2026

A novel oral PDE4 inhibitor prodrug for IBD demonstrated strong safety and efficacy in early trials, with phase II studies in ulcerative colitis and Crohn's disease set to begin, backed by robust funding and a top-tier clinical team. The drug's targeted delivery and tolerability differentiate it from competitors.

27 days ago - Transcripts

Palisade Bio Slides: Corporate presentation

Palisade Bio has posted slides in relation to its latest quarterly earnings report, which was published on June 4, 2026.

27 days ago - Filings

Palisade Bio to Participate in the Jefferies Global Healthcare Conference

Management presentation to take place on Thursday, June 4 th at 3:45 PM ET Register for the webcast here Denver, CO, May 27, 2026 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (Nasdaq: PALI) (“Palisade” or t...

5 weeks ago - GlobeNewsWire

Palisade Bio Slides: Corporate presentation

Palisade Bio has posted slides in relation to its latest quarterly earnings report, which was published on May 13, 2026.

7 weeks ago - Filings

Palisade Bio files $300M mixed securities shelf

17:28 EDT Palisade Bio (PALI) files $300M mixed securities shelf

7 weeks ago - TheFly

Palisade Bio Reports First Quarter 2026 Financial Results and Highlights Continued Clinical Progress of PALI-2108

Advancing potentially best-in-class once-daily oral, locally-activated PDE4 inhibitor prodrug for treatment of IBD Phase 2 Ulcerative Colitis (UC) trial expected to commence 3Q 2026 Strong balance she...

7 weeks ago - GlobeNewsWire

Palisade Bio Registration statement: Registration filing

Palisade Bio filed a registration statement on May 12, 2026, providing details about a securities offering with the SEC.

7 weeks ago - Filings

Palisade Bio Quarterly report: Q1 2026

Palisade Bio has published its Q1 2026 quarterly earnings report on May 12, 2026.

7 weeks ago - Filings

Palisade Bio Earnings release: Q1 2026

Palisade Bio released its Q1 2026 earnings on May 12, 2026, summarizing the period's financial results.

7 weeks ago - Filings

Palisade Bio Reports Additional Phase 1a/b Data Demonstrating Colon-Targeted Exposure and Sustained IC90 Coverage Supporting Once-Daily Dosing in Ulcerative Colitis

Data demonstrate colon tissue PDE4/cAMP pathway modulation and sustained active metabolite exposure above IC90 across the dosing interval

2 months ago - GlobeNewsWire

Palisade Bio Proxy statement: Proxy filing

Palisade Bio filed a proxy statement on April 29, 2026, providing details for shareholder voting and corporate governance matters.

2 months ago - Filings

Palisade Bio Proxy statement: Proxy filing

Palisade Bio filed a proxy statement on April 29, 2026, providing details for shareholder voting and corporate governance matters.

2 months ago - Filings

Palisade Bio Proxy statement: Proxy filing

Palisade Bio filed a proxy statement on April 17, 2026, providing details for shareholder voting and corporate governance matters.

2 months ago - Filings

Palisade Bio Transcript: 25th Annual Needham Virtual Healthcare Conference

A novel oral PDE4 inhibitor prodrug for IBD showed strong early efficacy and safety in UC and Crohn's, with 100% response in a UC phase Ib and robust PK/PD in Crohn's. Phase II trials are set for 2024, supported by $135M in cash and a precision medicine approach.

2 months ago - Transcripts

Palisade Bio Announces Abstract Selected for Poster Presentation at Digestive Disease Week (DDW) 2026

Poster presentation scheduled for Tuesday, May 5th at 12:30 PM CDT Denver, CO, April 16, 2026 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (Nasdaq: PALI) (“Palisade” or the “Company”), a clinical-stage biop...

2 months ago - GlobeNewsWire

Palisade Bio initiated with an Outperform at Wolfe Research

Wolfe Research analyst Andy Chen initiated coverage of Palisade Bio (PALI) with an Outperform rating and $7 price target The firm sees a “quiet 2026,” but is bullish into ulcerative…

2 months ago - TheFly

Palisade Bio to Present at the Needham & Co. 25th Annual Healthcare Conference

Virtual presentation scheduled for Thursday, April 16th at 2:15 PM ET Access the webcast here Denver, CO, April 08, 2026 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (Nasdaq: PALI) (“Palisade” or the “Compa...

3 months ago - GlobeNewsWire

Palisade Bio Slides: Corporate presentation

Palisade Bio has posted slides in relation to its latest quarterly earnings report, which was published on April 1, 2026.

3 months ago - Filings

Palisade Bio reaction to PALI-2108 data ‘looks misaligned’, says Clear Street

Clear Street keeps a Buy rating and $12 price target on Palisade Bio (PALI), saying the decline in the stock price after the Phase 1B Clinical Study of PALI-2108 in…

3 months ago - TheFly

Palisade Bio Transcript: Study result

Phase I-B data for PALI-2108 in fibrostenotic Crohn's disease showed strong safety, robust PK/PD, and early clinical activity, with 40% endoscopic response/remission in a refractory population. Once-daily oral dosing and dual anti-inflammatory/anti-fibrotic action support further development in broader Crohn's cohorts.

3 months ago - Transcripts

Palisade Bio Press release: Study result

Palisade Bio issued a press release on March 31, 2026, disclosing material business information to investors.

3 months ago - Filings