Puma Biotechnology, Inc. (PBYI)

NASDAQ: PBYI · Real-Time Price · USD
7.18
-0.06 (-0.83%)
May 29, 2026, 12:21 PM EDT - Market open
Market Cap365.46M +142.2%
Revenue (ttm)227.18M -2.4%
Net Income24.38M -35.9%
EPS0.48 -38.1%
Shares Out 50.90M
PE Ratio15.01
Forward PE26.84
Dividendn/a
Ex-Dividend Daten/a
Volume90,165
Open7.23
Previous Close7.24
Day's Range7.08 - 7.23
52-Week Range3.03 - 7.90
Beta1.23
AnalystsHold
Price Target5.00 (-30.36%)
Earnings DateMay 7, 2026

About PBYI

Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to enhance cancer care in the United States and internationally. It offers NERLYNX, an oral version of neratinib that is used to treat adult patients with early stage HER2-overexpressed/amplified breast cancer; and advanced or metastatic HER2-positive breast cancer when combined with capecitabine. The company also develops alisertib, a small molecule inhibitor of aurora kinase A for the treatment of hormone receptor positive breas... [Read more]

Industry Biotechnology
Sector Healthcare
Founded 2010
Employees 179
Stock Exchange NASDAQ
Ticker Symbol PBYI
Full Company Profile

Financial Performance

In 2025, Puma Biotechnology's revenue was $228.37 million, a decrease of -0.91% compared to the previous year's $230.47 million. Earnings were $31.11 million, an increase of 2.75%.

Financial Statements

Analyst Summary

According to one analyst, the rating for PBYI stock is "Hold" and the 12-month stock price target is $5.0.

Price Target
$5.0
(-30.36% downside)
Analyst Consensus: Hold

News

Puma Biotechnology Q1 Earnings Call Highlights

Puma Biotechnology NASDAQ: PBYI reported first-quarter 2026 total revenue of $44.8 million, driven primarily by NERLYNX product revenue net of $42.0 million and royalty revenue of $2.8 million, accord...

20 days ago - MarketBeat

Puma Biotechnology reports Q1 adjusted EPS (4c) vs (10c) last year

Reports Q1 revenue $44.8M vs $42M last year. “We are very pleased that the first quarter of 2026 marked another quarter of year-over-year demand increase resulting in our raising revenue…

21 days ago - TheFly

Puma Biotechnology sees Q2 revenue $52M-$55M, one estimate $52M

16:58 EDT Puma Biotechnology (PBYI) sees Q2 revenue $52M-$55M, one estimate $52M

21 days ago - TheFly

Puma Biotechnology Earnings Call Transcript: Q1 2026

Q1 2026 saw NERLYNX revenue decline sequentially due to inventory drawdown, but new patient starts rose 25% and the company is now debt-free. Updated guidance raises FY 2026 revenue and net income expectations, with strong clinical progress in biomarker-driven trials.

21 days ago - Transcripts

Puma Biotechnology Earnings release: Q1 2026

Puma Biotechnology released its Q1 2026 earnings on May 7, 2026, summarizing the period's financial results.

21 days ago - Filings

Puma Biotechnology Quarterly report: Q1 2026

Puma Biotechnology has published its Q1 2026 quarterly earnings report on May 7, 2026.

21 days ago - Filings

Puma Biotechnology Slides: Q1 2026

Puma Biotechnology has posted slides in relation to its Q1 2026 quarterly earnings report, which was published on May 7, 2026.

21 days ago - Filings

Puma Biotechnology Reports First Quarter 2026 Financial Results

LOS ANGELES--(BUSINESS WIRE)--Puma Biotechnology hosted a conference call and provided a corporate update on May 7, 2026, following release of its 1Q-2026 financial results.

21 days ago - Business Wire

Puma Biotechnology Reports Inducement Awards Under Nasdaq Listing Rule 5635(c)(4)

LOS ANGELES--(BUSINESS WIRE)--Puma Biotechnology reported inducement awards granted to six new hires in April 2026, as required under Nasdaq Listing Rule 5635(c)(4) .

22 days ago - Business Wire

Puma Biotechnology Proxy statement: Proxy filing

Puma Biotechnology filed a proxy statement on April 28, 2026, providing details for shareholder voting and corporate governance matters.

4 weeks ago - Filings

Puma Biotechnology Proxy statement: Proxy filing

Puma Biotechnology filed a proxy statement on April 28, 2026, providing details for shareholder voting and corporate governance matters.

4 weeks ago - Filings

Puma Biotechnology to Host Conference Call to Discuss First Quarter 2026 Financial Results

LOS ANGELES--(BUSINESS WIRE)--Puma Biotechnology will host a conference call on May 7 at 1:30 p.m. PT, following release of its first quarter 2026 financial results.

5 weeks ago - Business Wire

Puma Biotechnology Proxy statement: Proxy filing

Puma Biotechnology filed a proxy statement on April 7, 2026, providing details for shareholder voting and corporate governance matters.

7 weeks ago - Filings

Puma Biotechnology Transcript: TD Cowen 46th Annual Health Care Conference

NERLYNX continues to show strong commercial growth, with increasing revenues and improved patient tolerability. Alisertib advances in phase II trials for breast and lung cancers, with interim and full data readouts expected in 2026. Financial stability is supported by profitability and a near debt-free position.

3 months ago - Transcripts

Puma Biotechnology reports Q4 EPS 26c vs. 39c last year

Reports Q4 revenue $75.5M vs. $59.1M last year. “Our financial performance in the fourth quarter and full year 2025 demonstrates continued momentum, with net income marking our third consecutive year…

3 months ago - TheFly

Puma Biotechnology sees Q1 revenue $38M-$42M, one estimate $49M

Sees FY26 revenue $214M-$221M, one estimates $220M.

3 months ago - TheFly

Puma Biotechnology Earnings Call Transcript: Q4 2025

Q4 2025 saw strong revenue growth, with NERLYNX net product revenue and royalties both rising significantly. Clinical trials for alisertib are ahead of schedule, and full-year profitability was achieved for the third consecutive year.

3 months ago - Transcripts

Puma Biotechnology Annual report: Q4 2025

Puma Biotechnology has published its Q4 2025 annual report on February 26, 2026.

3 months ago - Filings

Puma Biotechnology Earnings release: Q4 2025

Puma Biotechnology released its Q4 2025 earnings on February 26, 2026, summarizing the period's financial results.

3 months ago - Filings

Puma Biotechnology Slides: Q4 2025

Puma Biotechnology has posted slides in relation to its Q4 2025 quarterly earnings report, which was published on February 26, 2026.

3 months ago - Filings

Puma Biotechnology Annual report: Q4 2025

Puma Biotechnology has published its Q4 2025 annual report on February 26, 2026.

3 months ago - Filings

Puma Biotechnology Reports Fourth Quarter and Full Year 2025 Financial Results

LOS ANGELES--(BUSINESS WIRE)--Puma Biotechnology issued its 4Q-2025 earnings release on Feb. 26 and followed with a conference call to review results.

3 months ago - Business Wire

Puma Biotechnology to Present at TD Cowen's 46th Annual Health Care Conference

LOS ANGELES--(BUSINESS WIRE)--Puma Biotechnology CEO & President Alan Auerbach will provide a corporate overview at the TD Cowen Health Care Conference on March 2 at 2:30 pm ET.

3 months ago - Business Wire

Puma Biotechnology to Host Conference Call to Discuss Fourth Quarter and Full Year 2025 Financial Results

LOS ANGELES--(BUSINESS WIRE)--Puma Biotechnology will issue its fourth quarter and full year 2025 results, followed be a conference call, after the close on Feb. 26, 2026.

3 months ago - Business Wire