Pliant Therapeutics, Inc. (PLRX)

NASDAQ: PLRX · Real-Time Price · USD
1.150
-0.015 (-1.29%)
At close: May 15, 2026, 4:00 PM EDT
1.140
-0.010 (-0.87%)
After-hours: May 15, 2026, 4:54 PM EDT
Market Cap71.20M -26.0%
Revenue (ttm)n/a
Net Income-113.22M
EPS-1.84
Shares Out 61.91M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume439,110
Open1.160
Previous Close1.165
Day's Range1.130 - 1.170
52-Week Range1.090 - 1.950
Beta1.21
AnalystsHold
Price Target2.67 (+132.17%)
Earnings DateMay 11, 2026

About PLRX

Pliant Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing integrin-based therapeutics for the treatment of solid tumors. The company’s lead product candidate is the PLN-101095, an oral, small molecule dual inhibitor of αvß8 and αvß1 integrins that is in Phase 1a/1b for the treatment of solid tumors. It is also developing drug discovery platform comprising proprietary library of over 15,000 integrin binding molecules, focusing on integrin-based target-mediated drug delivery. Pliant Therapeutics,... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Jun 3, 2020
Employees 49
Stock Exchange NASDAQ
Ticker Symbol PLRX
Full Company Profile

Financial Performance

Financial Statements

Analyst Summary

According to 4 analysts, the average rating for PLRX stock is "Hold." The 12-month stock price target is $2.67, which is an increase of 132.17% from the latest price.

Price Target
$2.67
(132.17% upside)
Analyst Consensus: Hold
Stock Forecasts

News

Pliant Therapeutics reports Q1 EPS (32c), consensus (36c)

“In the first quarter, our team showcased its clinical development capabilities, initiating FORTIFY, the Phase 1b trial of PLN-101095, ahead of schedule and dosing the first patient in April,” said…

4 days ago - TheFly

Pliant Therapeutics Provides Corporate Update and Reports First Quarter 2026 Financial Results

First participant dosed in FORTIFY, a Phase 1b indication expansion trial of PLN-101095 Oral presentation at AACR 2026 featured updated data from Phase 1 trial of PLN-101095 showing deepening of confi...

4 days ago - GlobeNewsWire

Pliant Therapeutics to Participate in the RBC Capital Markets Global Healthcare Conference

SOUTH SAN FRANCISCO, Calif., May 06, 2026 (GLOBE NEWSWIRE) -- Pliant Therapeutics, Inc. (Nasdaq: PLRX), a clinical-stage biotechnology company focused on the discovery and development of integrin-base...

9 days ago - GlobeNewsWire

Pliant Therapeutics doses first participant in FORTIFY expansion trial

Pliant Therapeutics (PLRX) announced the dosing of the first participant in the FORTIFY Phase 1b open-label indication expansion clinical trial of PLN-101095 in combination with pembrolizumab, in pati...

15 days ago - TheFly

Pliant Therapeutics Announces First Patient Dosed in FORTIFY, the Phase 1b Indication Expansion Trial Evaluating PLN-101095 in Patients with ICI-Refractory Solid Tumors

SOUTH SAN FRANCISCO, Calif., April 30, 2026 (GLOBE NEWSWIRE) -- Pliant Therapeutics (Nasdaq: PLRX) today announced the dosing of the first participant in the FORTIFY Phase 1b open-label indication exp...

15 days ago - GlobeNewsWire

Pliant announces presentation of updated data from Phase 1 trial of PLN-101095

Pliant Therapeutics (PLRX) announced the presentation of updated data from its Phase 1 trial of PLN-101095, in combination with pembrolizumab, in patients with immune checkpoint inhibitor-refractory a...

26 days ago - TheFly

Pliant Therapeutics Announces Presentation of Updated Data from the Phase 1 Trial of PLN-101095 in Patients with ICI-Refractory Solid Tumors at the 2026 AACR Annual Meeting

Confirmed responses deepened with an average maximum tumor reduction from baseline of 89% and median time on treatment increased to 19 months

27 days ago - GlobeNewsWire

Pliant Therapeutics files $300M mixed securities shelf

18:00 EDT Pliant Therapeutics (PLRX) files $300M mixed securities shelf

6 weeks ago - TheFly

Pliant Therapeutics Announces Upcoming Presentation of Phase 1 Clinical Trial of PLN-101095 in Patients with Solid Tumors at the 2026 AACR Annual Meeting

SOUTH SAN FRANCISCO, Calif., March 18, 2026 (GLOBE NEWSWIRE) -- Pliant Therapeutics, Inc. (Nasdaq: PLRX), a clinical-stage biotechnology company focused on the discovery and development of integrin-ba...

2 months ago - GlobeNewsWire

Pliant Therapeutics price target lowered to $3 from $4 at Canaccord

Canaccord lowered the firm’s price target on Pliant Therapeutics (PLRX) to $3 from $4 and keeps a Hold rating on the shares. The firm said Pliant reported financial results and…

2 months ago - TheFly

Pliant Therapeutics price target lowered to $3 from $4 at Piper Sandler

Piper Sandler lowered the firm’s price target on Pliant Therapeutics (PLRX) to $3 from $4 and keeps an Overweight rating on the shares. At Q4/FY25 earnings, Pliant provided a thoughtful…

2 months ago - TheFly

Pliant Therapeutics reports Q4 EPS (38c), consensus (38c)

“We ended 2025 with encouraging data from our lead oncology program in ICI-refractory patients, an area of unmet medical need, that informed the initiation of our accelerated development plan for…

2 months ago - TheFly

Pliant Therapeutics Provides Corporate Update and Reports Fourth Quarter 2025 Financial Results

PLN-101095 Phase 1 data showed deep and durable ongoing responses in checkpoint inhibitor refractory solid tumors PLN-101095 accelerated development plan underway with initiation of Phase 1b indicatio...

2 months ago - GlobeNewsWire

Pliant Therapeutics Transcript: Oppenheimer 36th Annual Healthcare Life Sciences Conference

Transitioned focus to oncology with lead integrin-targeting program PLN-101095, showing promising phase I results and a strong safety profile. Phase Ib study starts in Q2, with a robust cash position supporting aggressive development and ongoing evaluation of new pipeline and partnering opportunities.

2 months ago - Transcripts

Pliant Therapeutics to Participate in the Oppenheimer Healthcare Life Science Conference

SOUTH SAN FRANCISCO, Calif., Feb. 23, 2026 (GLOBE NEWSWIRE) -- Pliant Therapeutics, Inc. (Nasdaq: PLRX), a clinical-stage biotechnology company focused on the discovery and development of integrin-bas...

2 months ago - GlobeNewsWire

Pliant Therapeutics Transcript: Piper Sandler 37th Annual Healthcare Conference

Durable responses and a favorable safety profile were observed in the phase 1 study, prompting advancement to a phase 1b trial in non-small cell lung cancer and other tumors. The pipeline will expand with new programs by 2026, supported by a strong cash position through 2028.

5 months ago - Transcripts

Pliant Therapeutics announces interim data from PLN-101095

Pliant Therapeutics (PLRX) announced interim data from its Phase 1 dose escalation clinical trial evaluating PLN-101095, in combination with pembrolizumab, in patients with immune checkpoint inhibitor...

5 months ago - TheFly

Pliant Therapeutics Announces Interim Data from PLN-101095 in Patients with Immune Checkpoint Inhibitor-Refractory Advanced Solid Tumors

One complete response and three partial responses observed  in heavily pretreated ICI-secondary refractory patients in high dose cohorts Deep and durable ongoing responses with median time on treatmen...

5 months ago - GlobeNewsWire

Pliant Therapeutics to Participate in the Piper Sandler Healthcare Conference

SOUTH SAN FRANCISCO, Dec. 01, 2025 (GLOBE NEWSWIRE) -- Pliant Therapeutics, Inc. (Nasdaq: PLRX), a clinical-stage biotechnology company focused on the discovery and development of integrin-based thera...

5 months ago - GlobeNewsWire

Pliant Therapeutics reports Q3 EPS (43c), consensus (52c)

“During the third quarter, our team continued to advance our portfolio while winding down activities surrounding the BEACON-IPF trial,” said Bernard Coulie, President and Chief Executive Officer of Pl...

6 months ago - TheFly

Pliant Therapeutics Provides Corporate Update and Reports Third Quarter 2025 Financial Results

Oncology program advancing with data expected in the fourth quarter 2025 BEACON-IPF close out activities to be completed in the fourth quarter 2025 SOUTH SAN FRANCISCO, Calif., Nov. 06, 2025 (GLOBE NE...

6 months ago - GlobeNewsWire

Pliant Therapeutics downgraded to Underweight from Neutral at JPMorgan

JPMorgan downgraded Pliant Therapeutics (PLRX) to Underweight from Neutral without a price target The firm says the investment story “has remained in limbo” since the bexotegrast program for idiopathi...

7 months ago - TheFly

Pliant Therapeutics price target raised to $1.70 from $1.50 at Citi

Citi analyst David Lebowitz raised the firm’s price target on Pliant Therapeutics (PLRX) to $1.70 from $1.50 and keeps a Neutral rating on the shares post the Q2 report. The…

9 months ago - TheFly

Pliant Therapeutics price target lowered to $4 from $17 at Piper Sandler

Piper Sandler analyst Yasmeen Rahimi lowered the firm’s price target on Pliant Therapeutics (PLRX) to $4 from $17 and keeps an Overweight rating on the shares. The firm cites cash…

10 months ago - TheFly

Pliant Therapeutics reports Q2 EPS (71c), consensus (68c)

Reports Q2 cash, cash equivalents and short-term investments of $264.4M. The company has discontinued development of bexotegrast in idiopathic pulmonary fibrosis. “While our activities in the quarter ...

10 months ago - TheFly