Pliant Therapeutics, Inc. (PLRX)

NASDAQ: PLRX · Real-Time Price · USD
1.150
-0.020 (-1.71%)
At close: Jun 5, 2026, 4:00 PM EDT
1.143
-0.007 (-0.60%)
After-hours: Jun 5, 2026, 7:36 PM EDT
Market Cap71.21M -15.3%
Revenue (ttm)n/a
Net Income-113.22M
EPS-1.84
Shares Out 61.92M
PE Ration/a
Forward PEn/a
Dividendn/a
Ex-Dividend Daten/a
Volume409,113
Open1.160
Previous Close1.170
Day's Range1.130 - 1.180
52-Week Range1.090 - 1.950
Beta1.21
AnalystsHold
Price Target2.67 (+132.17%)
Earnings DateMay 11, 2026

About PLRX

Pliant Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing integrin-based therapeutics for the treatment of solid tumors. The company’s lead product candidate is the PLN-101095, an oral, small molecule dual inhibitor of αvß8 and αvß1 integrins that is in Phase 1a/1b for the treatment of solid tumors. It is also developing drug discovery platform comprising proprietary library of over 15,000 integrin binding molecules, focusing on integrin-based target-mediated drug delivery. Pliant Therapeutics,... [Read more]

Industry Biotechnology
Sector Healthcare
IPO Date Jun 3, 2020
Employees 49
Stock Exchange NASDAQ
Ticker Symbol PLRX
Full Company Profile

Financial Performance

Financial Statements

Analyst Summary

According to 6 analysts, the average rating for PLRX stock is "Hold." The 12-month stock price target is $2.67, which is an increase of 132.17% from the latest price.

Price Target
$2.67
(132.17% upside)
Analyst Consensus: Hold
Stock Forecasts

News

Pliant Therapeutics Announces Upcoming Presentation at the 2026 American Society of Clinical Oncology Annual Meeting

Highlights FORTIFY, the Phase 1b indication expansion trial of PLN-101095  enrolling patients with ICI-refractory solid tumors SOUTH SAN FRANCISCO, Calif., May 21, 2026 (GLOBE NEWSWIRE) -- Pliant Ther...

15 days ago - GlobeNewsWire

Pliant Therapeutics Transcript: RBC Capital Markets Global Healthcare Conference 2026

The company presented promising early clinical data for its integrin-blocking oncology program, with durable responses and a robust biomarker strategy. Preclinical siRNA delivery efforts are advancing, with muscle-targeting studies in primates and data expected this year. Key clinical and platform milestones are anticipated in 2026 and 2027.

17 days ago - Transcripts

Pliant Therapeutics reports Q1 EPS (32c), consensus (36c)

“In the first quarter, our team showcased its clinical development capabilities, initiating FORTIFY, the Phase 1b trial of PLN-101095, ahead of schedule and dosing the first patient in April,” said…

25 days ago - TheFly

Pliant Therapeutics Provides Corporate Update and Reports First Quarter 2026 Financial Results

First participant dosed in FORTIFY, a Phase 1b indication expansion trial of PLN-101095 Oral presentation at AACR 2026 featured updated data from Phase 1 trial of PLN-101095 showing deepening of confi...

25 days ago - GlobeNewsWire

Pliant Therapeutics Earnings release: Q1 2026

Pliant Therapeutics released its Q1 2026 earnings on May 11, 2026, summarizing the period's financial results.

25 days ago - Filings

Pliant Therapeutics Quarterly report: Q1 2026

Pliant Therapeutics has published its Q1 2026 quarterly earnings report on May 11, 2026.

25 days ago - Filings

Pliant Therapeutics to Participate in the RBC Capital Markets Global Healthcare Conference

SOUTH SAN FRANCISCO, Calif., May 06, 2026 (GLOBE NEWSWIRE) -- Pliant Therapeutics, Inc. (Nasdaq: PLRX), a clinical-stage biotechnology company focused on the discovery and development of integrin-base...

4 weeks ago - GlobeNewsWire

Pliant Therapeutics doses first participant in FORTIFY expansion trial

Pliant Therapeutics (PLRX) announced the dosing of the first participant in the FORTIFY Phase 1b open-label indication expansion clinical trial of PLN-101095 in combination with pembrolizumab, in pati...

5 weeks ago - TheFly

Pliant Therapeutics Announces First Patient Dosed in FORTIFY, the Phase 1b Indication Expansion Trial Evaluating PLN-101095 in Patients with ICI-Refractory Solid Tumors

SOUTH SAN FRANCISCO, Calif., April 30, 2026 (GLOBE NEWSWIRE) -- Pliant Therapeutics (Nasdaq: PLRX) today announced the dosing of the first participant in the FORTIFY Phase 1b open-label indication exp...

5 weeks ago - GlobeNewsWire

Pliant Therapeutics Proxy statement: Proxy filing

Pliant Therapeutics filed a proxy statement on April 22, 2026, providing details for shareholder voting and corporate governance matters.

6 weeks ago - Filings

Pliant Therapeutics Proxy statement: Proxy filing

Pliant Therapeutics filed a proxy statement on April 22, 2026, providing details for shareholder voting and corporate governance matters.

6 weeks ago - Filings

Pliant announces presentation of updated data from Phase 1 trial of PLN-101095

Pliant Therapeutics (PLRX) announced the presentation of updated data from its Phase 1 trial of PLN-101095, in combination with pembrolizumab, in patients with immune checkpoint inhibitor-refractory a...

6 weeks ago - TheFly

Pliant Therapeutics Announces Presentation of Updated Data from the Phase 1 Trial of PLN-101095 in Patients with ICI-Refractory Solid Tumors at the 2026 AACR Annual Meeting

Confirmed responses deepened with an average maximum tumor reduction from baseline of 89% and median time on treatment increased to 19 months

6 weeks ago - GlobeNewsWire

Pliant Therapeutics files $300M mixed securities shelf

18:00 EDT Pliant Therapeutics (PLRX) files $300M mixed securities shelf

2 months ago - TheFly

Pliant Therapeutics Registration statement: Registration filing

Pliant Therapeutics filed a registration statement on March 30, 2026, providing details about a securities offering with the SEC.

2 months ago - Filings

Pliant Therapeutics Announces Upcoming Presentation of Phase 1 Clinical Trial of PLN-101095 in Patients with Solid Tumors at the 2026 AACR Annual Meeting

SOUTH SAN FRANCISCO, Calif., March 18, 2026 (GLOBE NEWSWIRE) -- Pliant Therapeutics, Inc. (Nasdaq: PLRX), a clinical-stage biotechnology company focused on the discovery and development of integrin-ba...

2 months ago - GlobeNewsWire

Pliant Therapeutics price target lowered to $3 from $4 at Canaccord

Canaccord lowered the firm’s price target on Pliant Therapeutics (PLRX) to $3 from $4 and keeps a Hold rating on the shares. The firm said Pliant reported financial results and…

3 months ago - TheFly

Pliant Therapeutics price target lowered to $3 from $4 at Piper Sandler

Piper Sandler lowered the firm’s price target on Pliant Therapeutics (PLRX) to $3 from $4 and keeps an Overweight rating on the shares. At Q4/FY25 earnings, Pliant provided a thoughtful…

3 months ago - TheFly

Pliant Therapeutics Annual report: Q4 2025

Pliant Therapeutics has published its Q4 2025 annual report on March 11, 2026.

3 months ago - Filings

Pliant Therapeutics Earnings release: Q4 2025

Pliant Therapeutics released its Q4 2025 earnings on March 11, 2026, summarizing the period's financial results.

3 months ago - Filings

Pliant Therapeutics reports Q4 EPS (38c), consensus (38c)

“We ended 2025 with encouraging data from our lead oncology program in ICI-refractory patients, an area of unmet medical need, that informed the initiation of our accelerated development plan for…

3 months ago - TheFly

Pliant Therapeutics Provides Corporate Update and Reports Fourth Quarter 2025 Financial Results

PLN-101095 Phase 1 data showed deep and durable ongoing responses in checkpoint inhibitor refractory solid tumors PLN-101095 accelerated development plan underway with initiation of Phase 1b indicatio...

3 months ago - GlobeNewsWire

Pliant Therapeutics Transcript: Oppenheimer 36th Annual Healthcare Life Sciences Conference

Transitioned focus to oncology with lead integrin-targeting program PLN-101095, showing promising phase I results and a strong safety profile. Phase Ib study starts in Q2, with a robust cash position supporting aggressive development and ongoing evaluation of new pipeline and partnering opportunities.

3 months ago - Transcripts

Pliant Therapeutics to Participate in the Oppenheimer Healthcare Life Science Conference

SOUTH SAN FRANCISCO, Calif., Feb. 23, 2026 (GLOBE NEWSWIRE) -- Pliant Therapeutics, Inc. (Nasdaq: PLRX), a clinical-stage biotechnology company focused on the discovery and development of integrin-bas...

3 months ago - GlobeNewsWire

Pliant Therapeutics Transcript: Piper Sandler 37th Annual Healthcare Conference

Durable responses and a favorable safety profile were observed in the phase 1 study, prompting advancement to a phase 1b trial in non-small cell lung cancer and other tumors. The pipeline will expand with new programs by 2026, supported by a strong cash position through 2028.

6 months ago - Transcripts